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| 1 | End of Life Experience of Symptom Cluster and Their Management in Hong Kong Chinese Patients with Lung Cancer Who Receive Palliative Radiotherapy显示文摘Breathlessness, fatigue, and anxiety are distressing symptoms for patients with advanced lung cancer, however, they are not relieved by palliative RT and are often viewed as neglected areas of clinical practice. This paper aims to review def initions of, and explore patients' experiences of, breathlessness, fatigue, and anxiety. Further, it will outline existing approaches, both pharmacological and non-pharmacological, to treat them. Current treatments and perceptions of these symptoms will be discussed in the context of Hong Kong health care service. The review of literature also shows that breathlessness, fatigue and anxiety appears to have similar emotional origins. A contemporary approach of using a common pyschoeducational intervention to treat these symptoms together as a cluster in end of life care will be discussed. | Carmen W.H. CHAN S.Y. CHAIR Y.Y. CHUI | 2009 | 中国肺癌杂志2009，12，5： | 20 |
| 2 | 血管性认知障碍的诊断标准:国际血管性行为与认知障碍学会的申明显示文摘长期以来,脑血管病(CVD)就被认为是认知损害的一个重要原因,但是有关脑血管病后认知障碍的概念化却有着一段多变的历史。'动脉变硬'或脑的动脉粥样硬化是'老化'的原因,是存在已久的观点,在20世纪60年代受到了来自英格兰纽卡斯尔的神经病理学研究的质疑。这些研究表明,血管性痴呆(vascular dementia,Va D)与超过一定程度的多发性脑梗死有关。 | 徐岩 郭起浩 Sachdev P Kalaria R O'Brien J Skoog I Alladi S Black SE Blacker D Blazer DG Chen C Chui H Ganguli M Jellinger K Jeste DV Pasquier F Paulsen J Prins N Rockwood K Roman G Scheltens P | 2014 | 神经病学与神经康复学杂志2014，11，3： | 19 |
| 3 | 皮质下小血管病诊断的共识声明显示文摘血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病(Binswanger's disease, BD)的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组,存在缺氧缺血、腔隙性梗死和炎症,它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物,这将有助于诊断以及将来协作性治疗试验的患者选择。 | Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师 张劼 陈涵丰 俞娅美 徐子奇 罗本燕 | 2016 | 国际脑血管病杂志2016，24，6： | 18 |
| 4 | Speciation of heavy metals in surface sediments from Suzhou Creek显示文摘九个元素(作为, Cd , Cr , Cu , Fe , Mn , Ni , Pb , Zn )在在从苏州的 7 个地点(地点 1 鈥?)的沉积样品,在上海的溪与参考( BCR )(顺序的抽取( SE ))的社区 Bareau 被分析协议和同时提取的金属( SEM ) /acid 估计金属 bioavailability 的不稳定的硫化物( AVS )过程并且在这个区域的毒物学。结果证明 BCR 抽取能为在沉积估计金属的潜在的 bioavailability 和毒性与 AVS 方法作为一个另外的工具被利用。从 S5 (地点 5 ) 的污染比从另外的地点,特别 Pb, Cu 和 Zn 更严重。在所有这些地点之中,, Fe 的超过 80% 全部的集中在剩余部分存在 Cr,也在剩余部分(超过 50%) 统治的 Mn。当 Cd, Ni 和 Zn (超过 35%) 主要在非稳定的阶段时。Cu 与可氧化的阶段有一种强壮的亲密关系, Pb 从地点变化了到地点。SEM/AVS 比率是在这些沉积的不到一个,结果暗示 Zn 和 Ni 的多数(>40%) 被绑在 AVS。相反, Pb, Cu 和 Cd 由于他们 SEM-Pb, Cu,到相应全部的集中的 Cd 和相对高的 porewater 集中的低定量是到 AVS 的小界限。 | 陈炜 钱光人 LIM Teik Thye CHUI Peng-cheong | 2007 | Journal of Shanghai University(English Edition)2007，11，4： | 10 |
| 5 | SHIFT-INVARIANT BI-INNER PRODUCT FUNCTIONALS ARE INNER PRODUCTS显示文摘Bi-inner product functionals generated by a pair of Bessel sequences of L2 functions are introduced. It is shown that these functionals are constant multiples of the inner products of L2 and l2, if and only if they are shift-invariant both in space (or time) and in Phase. This result is then applied to characterize dual frames and bi-orthogonal Riesz bases of | Charles K. Chui (1) Xianliang Shi (1) | 1999 | Analysis in Theory and Applications1999，15，1： | 10 |
| 6 | Autophagy is involved in oral rAAV/Aβ vaccine-induced Aβ clearance in APP/PS1 transgenic mice显示文摘The imbalance between β-amyloid(Aβ) generation and clearance plays a fundamental role in the pathogenesis of Alzheimer 's disease(AD). The sporadic form of AD is characterized by an overall impairment in Aβ clearance. Immunotherapy targeting Aβ clearance is believed to be a promising approach and is under active clinical investigation. Autophagy is a conserved pathway for degrading abnormal protein aggregates and is crucial for Aβ clearance. We previously reported that oral vaccination with a recombinant AAV/Aβ vaccine increased the clearance of Aβ from the brain and improved cognitive ability in AD animal models, while the underlying mechanisms were not well understood. In this study, we first demonstrated that oral vaccination with rAAV/Aβ decreased the p62 level and up-regulated the LC3BII/LC3B-I ratio in APP/PS1 mouse brain, suggesting enhanced autophagy. Further, inhibition of the Akt/m TOR pathway may account for autophagy enhancement. We also found increased anti-Aβ antibodies in the sera of APP/PS1 mice with oralvaccination, accompanied by elevation of complement factors C1 q and C3 levels in the brain. Our results indicate that autophagy is closely involved in oral vaccination-induced Aβ clearance, and modulating the autophagy pathway may be an important strategy for AD prevention and intervention. | He-Cheng Wang Tao Zhang Bolati Kuerban Ying-Lan Jin Weidong Le Hideo Hara Dong-Sheng Fan Yan-Jiang Wang Takeshi Tabira De-Hua Chui | 2015 | Neuroscience Bulletin2015，31，4： | 8 |
| 7 | Physics towards next generation Li secondary batteries materials:A short review from computational materials design perspective显示文摘The physics that associated with the performance of lithium secondary batteries(LSB)are reviewed.The key physical problems in LSB include the electronic conduction mechanism,kinetics and thermodynamics of lithium ion migration,electrode/electrolyte surface/interface,structural(phase)and thermodynamics stability of the electrode materials,physics of intercalation and deintercalation.The relationship between the physical/chemical nature of the LSB materials and the batteries performance is summarized and discussed.A general thread of computational materials design for LSB materials is emphasized concerning all the discussed physics problems.In order to fasten the progress of the new materials discovery and design for the next generation LSB,the Materials Genome Initiative(MGI)for LSB materials is a promising strategy and the related requirements are highlighted. | OUYANG ChuYing CHEN LiQuan | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，12： | 6 |
| 8 | 数字化重构行业价值链显示文摘中国作为全球数字科技大国,未来拥有巨大潜力。数字化的伟力正在颠覆现状、重构价值链,并催生出大量充满活力的中国数字企业,从而不断增强着中国经济的国际竞争力。不过,未来还有更多变化值得期待。随着中国的数字化进程逐步推进,各个行业的价值链都将迎来收入和利润池的彻底变革。虽然这种创造性颠覆将发生在世界每一个角落,但由于中国的传统行业效率低下、新技术和业务的商业化潜力巨大,这一变化在中国将显得尤为迅猛和激烈。在本报告中,麦肯锡全球研究院(MGI)对中国的数字化体系以及各行业的数字化程度进行了评估。为了解数字化如何颠覆现状、决定竞争输赢,麦肯锡研究院探究了去中介化(Disintermediation)、分散化(Disaggregation)和非物质化(Dematerialization)这三种数字化推动力将如何帮助企业重塑价值链、加速变革步伐。本报告也将探讨政策制定者应如何推动支持数字经济转型,以及企业如何抉择才能为即将到来的变革浪潮做好准备。 | 华强森 成政珉 王玮 James Manyika Michael Chui 黄家仪 | 2018 | 科技中国2018，，3： | 6 |
| 9 | 中国数字经济如何引领全球新趋势显示文摘中国取得的数字化成就远超多数关注者的预期:中国目前已是全球领先的数字技术投资与应用大国,孕育了全世界三分之一的“独角兽”公司;市场体量庞大,能够推动数字商业模式迅速投入商用, | 华强森 成政珉 王玮 James Manyika Michael Chui 黄家仪 | 2017 | 科技中国2017，，11： | 6 |
| 10 | Duration-dependent regulation of autophagy by isoflurane exposure in aged rats显示文摘Current evidence suggests a central role for autophagy in many inflammatory brain disorders, including Alzheimer's disease(AD). Furthermore, it is also well accepted that some inhalation anesthetics, such as isoflurane, may cause ADlike neuropathogenesis and resultant postoperative cognitive dysfunction, especially in the elderly population. However, the impact of inhalation anesthetics on autophagic components in the brain remains to be documented. Hence, our objective was to investigate the effects of different durations of isoflurane exposure on hippocampus-dependent learning and hippocampal autophagy in aged rats. Aged Sprague-Dawley rats(20 months old) were randomly exposed to 1.5% isoflurane or 100% oxygen for 1 or 4 h. Animals were then trained in the Morris water maze(4 trials/day for 5 consecutive days). Hippocampal phagophore formation markers, beclin 1 and protein microtubule-associated protein 1 light chain-3B(LC3B), as well as p62, an indicator of autophagic flux, were quantified by western blotting. There was no significant difference in the escape latencies and time spent in the target quadrant, as well as hippocampal expression of beclin 1, LC3 BII, and p62 at 24 h post-anesthesia between the1-h isoflurane-exposed rats and their controls(P >0.05). Four-hour exposure to isoflurane resulted in spatial learning and memory deficits, as evidenced by prolonged escape latencies on days 4 and 5 postanesthesia and less time spent in the target quadrant than sham-exposed animals(P <0.05). These events were accompanied by a decline in hippocampal expression of LC3B-I, LC3B-II, and beclin 1 24 h after isoflurane(P <0.01 and P <0.05). Nevertheless, no significant change in p62 expression was found. Further kinetics study of autophagic changes induced by 4 h of isoflurane showed a transient upregulation of LC3B-I, LC3B-II, and beclin 1 at the end of exposure and a subsequent striking decrease w ithin 12–24 h post-anesthesia(P <0.05). Hippocampal p62 p eaked at 6 h but subsequently resolved. These results from our pilot in vivo study support a durationdependent relationship between 1.5% isoflurane exposure, and s patial cognitive function as well as hippocampal phagophore formation. | Zheng-Qian Li Lun-Xu Li Na Mo Yi-Yun Cao Bolati Kuerban Yao-Xian Liang Dong-Sheng Fan De-Hua Chui Xiang-Yang Guo | 2015 | Neuroscience Bulletin2015，31，4： | 5 |
| 11 | 结构性异体骨移植在髋臼假体翻修术中的应用显示文摘 | 姜文学 Myung Chui Yoo | 2002 | 中国矫形外科杂志2002，9，11： | 5 |
| 12 | Cross-sectional evaluation of the adequacy of guardianship by family members of community-residing persons with mental disorders in Changning District, Shanghai显示文摘 | Qiongting ZHANG Hao CHEN Kang JU Xin NIU Lanjun SONG Jia CHUI | 2015 | 上海精神医学2015，27，1： | 4 |
| 13 | BOUNDED LINEAR OPERATORS THAT COMMUTE WITH SHIFTS ARE SCALED IDENTITY显示文摘We prove that every bounded linear operator on, that commutes with both the spatial shift operator and the phase shaift operator must be a constant multiple of the identity. Wealso apply this result to identify analysis-synthesis dual Lq-Lp pairs and to characterize bi-orthogonal unconditional bases of Lq-Lp, where p-1 | C. K. Chui (1) Xianliang Shi (1) | 1999 | Analysis in Theory and Applications1999，15，3： | 4 |
| 14 | First-principles study of lithium intercalated bilayer graphene显示文摘Lithium intercalated bilayer graphene has been investigated using first-principles density functional theory calculations. Results show that there exist AB and AA stacking sequences for bilayer graphene in which the latter is more favorable for the Li storage and the former will evolve into the latter with the intercalation of Li ions. The relationship between the interlayer distance of two graphene sheets and the intercalated capacity of Li ions is discussed. It is found that structural defect is identified to store Li ions more favorably than pristine bilayer graphene and an isolated C atom vacancy in bilayer graphene can capture three Li ions between two graphene sheets. | ZHOU JingJing ZHOU WeiWei GUAN ChunMei SHEN JingQin OUYANG ChuYing LEI MinSheng SHI SiQi TANG WeiHua | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，8： | 4 |
| 15 | Phase-controlled synthesis of thermally stable nitrogen-doped carbon supported iron catalysts for highly efficient Fischer-Tropsch synthesis显示文摘Iron-based nan oparticles with un iform and high particle dispersi on,which are supported on carb on structures,have been used for various applications.However,their preparation still suffers from complicated synthesis involving multiple steps and from the high price of precursors and solve nts.In the prese nt work,a new carbon en capsulated iron-carbide nano particle supported on n itroge rvdoped porous carbon(Fe5C2@C/NPC)structure was introduced.It was made using a simple solid-state reaction with sequential thermal treatments.Fe5C2@C/NPC is a highly active and stable catalyst for the high-temperature Fischer-Tropsch synthesis reaction.It showed very high hydrocarbon productivity(4.71 gHc gcat^-1·h^-1)with high CO conversions(up to 96%). | Jin Hee Lee Hack-Keun Lee Dong Hyun Chun Hyunkyung Choi Geun Bae Rhim Min Hye Youn Heondo Jeong Shin Wook Kang Jung-ll Yang Heon Jung Chui Sung Kim Ji Chan Park | 2019 | Nano Research2019，12，10： | 4 |
| 16 | 基于静态弯曲性能的木质工字梁设计计算方法探讨显示文摘参照钢质工字梁静态弯曲理论,对木质工字梁(IJ)的'荷载-位移'曲线、IJ正应力理论计算值与实测值、IJ整梁挠度理论计算值与实测值的对比分析,结果认定:1)钢质工字梁的静态弯曲理论计算公式,可用于IJ弹性段应力和挠度的分析计算;2)IJ整梁静态弯曲性能的分析计算时,应注意IJ上翼缘压缩特性和下翼缘拉伸特性的差异。 | 张宏健 董春雷 Ying Hei Chui 袁福兴 | 2009 | 木材工业2009，23，4： | 3 |
| 17 | 云计算、海量数据和智能设施:值得关注的十种由技术带动的商业趋势显示文摘不断发展并迅速投入运用的各种技术正在颠覆传统的商业模式。企业高管必须从战略高度上思考问题,考虑如何使自己的组织为迎接充满挑战性的新环境而未雨绸缪。 | Jacques Bughin Michael Chui James Manyika | 2010 | 海峡科技与产业2010，23，11： | 3 |
| 18 | Sustainable Application of a Novel Water Cycle Using Seawater for Toilet Flushing显示文摘 | Xiaoming Liu Ji Dai Di Wu Feng Jiang Guanghao Chen Ho-Kwong Chui Mark C. M. van Loosdrecht | 2016 | Engineering2016，2，4： | 3 |
| 19 | Spatial modulation of nanopattern dimensions by combining interference lithography and grayscale-patterned secondary exposure显示文摘Functional nanostructures are exploited for a variety of cutting-edge fields including plasmonics,metasurfaces,and biosensors,just to name a few.Some applications require nanostructures with uniform feature sizes while others rely on spatially varying morphologies.However,fine manipulation of the feature size over a large area remains a substantial challenge because mainstream approaches to precise nanopatterning are based on low-throughput pixel-by-pixel processing,such as those utilizing focused beams of photons,electrons,or ions.In this work,we provide a solution toward wafer-scale,arbitrary modulation of feature size distribution by introducing a lithographic portfolio combining interference lithography(IL)and grayscale-patterned secondary exposure(SE).Employed after the high-throughput IL,a SE with patterned intensity distribution spatially modulates the dimensions of photoresist nanostructures.Based on this approach,we successfully fabricated 4-inch wafer-scale nanogratings with uniform linewidths of<5%variation,using grayscale-patterned SE to compensate for the linewidth difference caused by the Gaussian distribution of the laser beams in the IL.Besides,we also demonstrated a wafer-scale structural color painting by spatially modulating the filling ratio to achieve gradient grayscale color using SE. | Zhuofei Gan Hongtao Feng Liyang Chen Siyi Min Chuwei Liang Menghong Xu Zijie Jiang Zhao Sun Chuying Sun Dehu Cui Wen-Di Li | 2022 | Light(Science & Applications)2022，11，5： | 3 |
| 20 | 木结构楼板托梁用木质工字梁静曲性能的设计显示文摘为了探知木结构建筑用木质工字梁的设计方法,本文以用杨木LVL作翼缘、竹定向刨花板作腹板的楼面托梁用竹木工字梁(IJ)为研究对象,分析讨论了设计荷载、木结构建筑结构规范尺寸、IJ的截面尺寸和包括蠕变在内的IJ的静曲性能及其它们之间的关系并得到了试验验证。研究结果表明:钢质工字梁的科学理论可以作为工程用IJ弹性段静曲性能的设计依据,并可满足木结构建筑楼面托梁用IJ的设计、制造要求。同时提出尽快建立健全我国木结构建筑和木质建筑材料统一规范、标准,以正确指导IJ及其翼缘、腹板材料设计、制造和应用的若干建议。 | 张宏健 Ying Hei Chui 董春雷 袁福兴 冯琦 | 2009 | 中国建材科技2009，，6： | 2 |
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