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2篇 您的检索式:作者名="Chunkang Yang"
    题名 作者 年代 出处 被引量
1Interleukin‐17 enhances the production of interferon‐γ and tumour necrosis factor‐α by bone marrow T lymphocytes from patients with lower risk myelodysplastic syndromes显示文摘Zheng Zhang Xiao Li Juan Guo Feng Xu Qi He Youshan Zhao Yujuan Yang Shucheng Gu Yan Zhang Lingyun Wu Chunkang Chang 2013Eur J Haematol2013,,5:2
2The expression of chemokine MCP-1 in colorectal carcinoma and its relationship to the infiltration of macrophage显示文摘Objective: To study the expression of MCP-1 in colorectal carcinoma and its relationship to the infiltration of the macrophage and to the biological behaviour of infiltration and metastasis of colorectal carcinoma. Methods: The expression of the MCP-1 mRNA was assessed in colorectal carcinoma collected freshly from surgical specimen by RT-PCR and the expres- sion of the MCP-1 protein was assessed in colorectal carcinoma collected from surgical specimen by immunohistochemistry. The tumor infiltrating cell and macrophage were also investigated by immunohistochemistry. Results: All the 12 specimens of colorectal carcinoma detected by RT-PCR expressed the MCP-1 mRNA; MCP-1 protein was detected in 90℅ (36/40) cases of the tumor; The expression of the MCP-1 protein in colorectal carcinoma correlated negatively with its state of metastasis and the Dukes’ stage. But a postive correlation was found between the expression of MCP-1 and the infiltrated macrophage. The stron- ger expression of MCP-1, the more number of the infiltrated macrophage. Conclusion: The expression of chemokine MCP-1 in colorectal carcinoma may influence its biological behaviour of infiltration and metastasis, and can attract the immuno-cell to the local of the tumor, such as Macrophage.Chunkang Yang Daoda Chen Kai Huang Huihao Zhang Dongpo Xu Yuan Tian Jinhui Zhang 2006The Chinese-German Journal of Clinical Oncology2006,5,5:1
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