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| 1 | Protective effects of a new metalloporphyrin on paraquat-induced oxidative stress and apoptosis in N27 cells显示文摘Paraquat (PQ, 1,1'-dimethyl-4,4'-bipyridinium ) ,使用得广泛地的除草剂,为 Parkinson 的疾病的发展作为一个潜在的 etiologic 因素被建议了。在最近的年里,许多研究集中于 PQ neurotoxicity 的机制。在这研究,我们检验了锰( III )的 neuroprotective 效果 meso-tetrakis ( N , N'-diethylimidazolium )卟啉( MnTDM ),超级氧化物 dismutase/catalase 模仿,在在 1RB ( 3 )的 导致PQ 的氧化应力和 apoptosis 上一( 27 )( N27 )房间,一根 dopaminergic neuronal 房间线。结果显示 MnTDM 显著地稀释了房间生存能力,谷胱甘肽弄空,和反应的氧种类生产的导致 PQ 的损失。MnTDM 也改善了 apoptosis 的导致 PQ 的词法原子变化和 apoptosis 的增加的率。另外,我们的数据提供 MnTDM 压制了导致 PQ 的 caspase-3 劈开的直接证据,可能 PQ neurotoxicity 的一个关键事件。这些观察建议了那个氧化压力, apoptosis 在导致 PQ 的 neurotoxicity 被含有,这毒性能被 MnTDM 阻止。这些调查结果也为 Parkinson 与氧化应力联系的疾病和另外的混乱建议了一条新奇治疗学的途径。 | Ping Chen Ang Li Mengjie Zhang Meilan He Zhen Chen Xiaokang Wu Chunjun Zhao Shilong Wang Liping Liang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，2： | 4 |
| 2 | Enhanced electroluminescence of europium (Ⅲ) complex by terbium (Ⅲ) substitution in organic light emitting diodes显示文摘 | Zhao Dongxu Hong Ziruo Liang Chunjun Dan Zhao Liu Xingyuan Li Wenlian Lee C S Lee S T | 2000 | Thin Soild Films2000，363，： | 1 |
| 3 | Enhanced electroluminescence of europium(Ⅲ)complex by terbium(Ⅲ)substitution in organic light emitting diodes显示文摘 | Zhao Dongxu Hong Ziruo Liang Chunjun et al. | | 0，，： | 1 |
| 4 | Partners selection process and optimization model for virtual corporations based on genetic algorithms显示文摘 | Feng Weidong Chen Jian Zhao Chunjun | 2000 | Journal of Tsinghua Univ (Sci &Tech)2000，40，10： | 1 |
| 5 | Enhanced electroluminescence of europium ( Ⅲ ) complex by terbium (Ⅲ)substitution in organic light emitting diodes 显示文摘 | Zhao Dongxu Hong Ziruo Liang Chunjun | 2000 | Thin Soild Films2000，363，： | 1 |
| 6 | Enhanced electroluminescence of europium(Ⅲ)complex by terbium(Ⅲ)substitution in organic light emitting diodes 显示文摘 | Zhao Dongxu Hong Ziruo Liang Chunjun | 2000 | Thin Solid Film2000，363，： | 1 |
| 7 | Partners selection process and optimization model for virtual corporations based on genetic algorithms显示文摘 | Feng Weidong Chen Jian Zhao Chunjun | 2000 | Journal of Tsinghua Univ(Sci &Tech)2000，40，10： | 1 |
| 8 | Effect on vibration of the complementary gas flow between centrifugal compressor stages 显示文摘 | JI Chunjun LI Jiana ZHAO Heng | 2007 | Journal of Vibration Measurement & Diagnosis2007，，： | 1 |
| 9 | Partners selection process and optimization model for virtual corporations based on genetic algorithms显示文摘 | Feng Weidong Chen Jian Zhao Chunjun | 2000 | Journal of Tsinghua Univ (Sci & Tech)2000，40，10： | 1 |
| 10 | A high-density intervarietal map of the wheat genome enriched with markers derived from expressed sequence tags显示文摘 | Shulin Xue Zhengzhi Zhang Feng Lin Zhongxin Kong Yong Cao Chunjun Li Hongying Yi Mingfeng Mei Huilan Zhu Jizhong Wu Haibin Xu Dongmei Zhao Dagang Tian Caiqin Zhang Zhengqiang Ma | 2008 | Theoretical and Applied Genetics2008，，2： | 1 |
| 11 | A high-density intervarietal map of the wheat genome enriched with markers derived from expressed sequence tags显示文摘 | Shulin Xue Zhengzhi Zhang Feng Lin Zhongxin Kong Yong Cao Chunjun Li Hongying Yi Mingfeng Mei Huilan Zhu Jizhong Wu Haibin Xu Dongmei Zhao Dagang Tian Caiqin Zhang Zhengqiang Ma | 2008 | Theoretical and Applied Genetics2008，，2： | 1 |
| 12 | Immunological Exploration of Helicobacter pylori Serotype O2 O-Antigen by Using a Synthetic Glycan Library显示文摘Helicobacter pylori(H.pylori)infection is a threat to human health.The lipopolysaccharide(LPS)O-antigen holds promise for developing vaccines.It is meaningful to explore the immunological activity of oligosaccharides with different lengths and frameshifts for antigen development.Herein,a glycan library of H.pylori O2 O-antigen containing eight fragments is constructed.After screening with anti-H.pylori O2 LPS sera and patients’sera by glycan microarray,the disaccharide HPO2G-2b and trisaccharide HPO2G-3a show strong antigenicity and then are separately conjugated with carrier protein CRM197.Both glycoconjugates elicit a robust immunoglobulin G(IgG)immune response in rabbits.The anti-HPO2G-3a IgG antibodies possess a much stronger binding affinity with the LPS and bacteria of H.pylori O2 than the anti-HPO2G-2b IgG antibodies.There is no cross-reaction between both sera IgG antibodies with LPS and bacteria of H.pylori O1,O6,and E.coli.The results demonstrate the trisaccharide HPO2G-3a is a promising candidate for H.pylori vaccine development. | Ming Zhao Guangzong Tian Chunjun Qin Xiaopeng Zou Peter H. Seeberger Jing Hu Jian Yin | 2024 | Chinese Journal of Chemistry2024，42，3： | 0 |
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