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7篇 您的检索式:作者名="Choroomi"
    题名 作者 年代 出处 被引量
1Use of ultrasound in187 infants with suspected infantile hypertrophic pyloricstenosis显示文摘Forster N Haddad RL Choroomi S 2007Australas Radiol2007,51,6:1
2A novel technique of otic barotraumas management using modified intravenous caunulae 显示文摘Zhang Q Banks C Choroomi S 2013Eur Arch Otorhinolaryngol2013,270,:1
3Use of ultrasound in 187 infants with suspected infantile hypertrophic pyloric stenosis 显示文摘Forster N Haddad RL Choroomi S 2007Australas Radiol2007,51,6:1
4Use of ultrasound in 187 infants with suspected infantile hypertrophic pyloric stenosis显示文摘Forster N Haddad RL Choroomi S 0,,06:1
5Use of ultra- sound in 187 infants with suspected infantile hyperrophic pyl- tic stenosis 显示文摘Forster N Haddad RL Choroomi S 2007Australas Radiol2007,51,6:1
6Use of ultrasound in187 infants with suspected infantile hypertrophic pyloficstenosis 显示文摘Forster N Haddad RL Choroomi S 2007Australas Radiol2007,51,6:1
7Tunable hybrid hydrogels with multicellular spheroids for modeling desmoplastic pancreatic cancer显示文摘The tumor microenvironment consists of diverse,complex etiological factors.The matrix component of pancreatic ductal adenocarcinoma(PDAC)plays an important role not only in physical properties such as tissue rigidity but also in cancer progression and therapeutic responsiveness.Although significant efforts have been made to model desmoplastic PDAC,existing models could not fully recapitulate the etiology to mimic and understand the progression of PDAC.Here,two major components in desmoplastic pancreatic matrices,hyaluronic acid-and gelatin-based hydrogels,are engineered to provide matrices for tumor spheroids composed of PDAC and cancer-associated fibroblasts(CAF).Shape analysis profiles reveals that incorporating CAF contributes to a more compact tissue formation.Higher expression levels of markers associated with proliferation,epithelial to mesenchymal transition,mechanotransduction,and progression are observed for cancer-CAF spheroids cultured in hyper desmoplastic matrix-mimicking hydrogels,while the trend can be observed when those are cultured in desmoplastic matrix-mimicking hydrogels with the presence of transforming growth factor-β1(TGF-β1).The proposed multicellular pancreatic tumor model,in combination with proper mechanical properties and TGF-β1 supplement,makes strides in developing advanced pancreatic models for resembling and monitoring the progression of pancreatic tumors,which could be potentially applicable for realizing personalized medicine and drug testing applications.Menekse Ermis Natashya Falcone Natan Roberto de Barros Marvin Mecwan Reihaneh Haghniaz Auveen Choroomi Mahsa Monirizad Yeji Lee Jihyeon Song Hyun-Jong Cho Yangzhi Zhu Heemin Kang Mehmet R.Dokmeci Ali Khademhosseini Junmin Lee Han-Jun Kim 2023Bioactive Materials2023,,7:0
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