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| 1 | Increased expression of the nitric oxide synthase gene and protein in corpus cavernosum by repeated dosing of udenafil in a rat model of chemical diabetogenesis显示文摘可勃起的机能障碍(编辑) 是糖尿病 mellitus (DM ) 的主要复杂并发症。这研究在糖尿病的老鼠的阴茎海绵体(CC ) 调查在编辑和组成的氮的氧化物 synthase (cNOS ) 的 downregulation 之间的关系。它也检验 udenafil 的效果,一种 phosphodiesterase 类型 5 (PDE5 ) 禁止者,在编辑和 cNOS 表示层次上。在 16 星期有在糖尿病的老鼠的 udenafil 的每日的口头的处理以后, intracavernous 压力 / 平均数动脉的压力(ICP/MAP ) 比率被记录测量可勃起的功能,并且 cNOS 表示用反向的 transcriptase (RT ) 被测量 -PCR 和 immunoblots。尽管 ICP/MAP 比率和 endothelial NOS (eNOS ) 和在 CC 的 neuronal NOS (nNOS ) 的表达式层次显著地在糖尿病的老鼠被减少,长期的 udenafil 处理改进了可勃起的函数并且与糖尿病的控制相比增加了 cNOS 表示。这些调查结果建议在 DM 的编辑是仔细,与减少的 cNOS 有关,在 CC 和那 udenafil 的表示有能力由 modulating cNOS 补偿这个病理学的变化表示。Udenafil 也在 cGMP (周期的 guanosine monophosphate ) 有一个禁止的角色降级。 | GJ Ahn HK Chung CH Lee KK Kang BO Ahn | 2009 | Asian Journal of Andrology2009，11，4： | 2 |
| 2 | Real-time imaging of trapping and ureasedependent transmigration of Cryptococcus neoformans in mouse brain显示文摘 | Shi M Li SS Zheng C Jones GJ Kim KS Zhou H Kubes P Mody CH | 2010 | J Clin Invest2010，120，5： | 1 |
| 3 | Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central rentinal vein occlusion显示文摘 | Park CH Jutffe GJ Fekrat S | 2003 | Am J Ophthalmol2003，136，： | 1 |
| 4 | Two primary brain tumours, meningioma and glioblastoma multiforme, in opposite hemispheres of the same patient显示文摘 | Lee GJ Chang CH Wang LC | 2002 | J Clin Neurosci2002，9，： | 1 |
| 5 | Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts:role of the Jun NH2-terminal kinase显示文摘 | Frost RA Nystrom GJ Lang CH | 2003 | Am J Physiol2003，285，5： | 1 |
| 6 | Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output显示文摘 | Lang CH Dobrescu C Bagby GJ | 1992 | Endocrinology1992，130，1： | 1 |
| 7 | Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion显示文摘 | Jaffe GJ Fekrat S | 2003 | Am J Ophthalmol2003，136，3： | 1 |
| 8 | Regulation of neural stem cell differentiation in the forebrain 显示文摘 | Bartlett PF Brooker GJ Faux CH | 1998 | Immunol Cell Biol1998，76，5： | 1 |
| 9 | Aerobic plate counts as a measure of hazard analys is critical control point effectiveness in a pork processing plant 显示文摘 | Hong CH Todd EC Bahk GJ | 2008 | J Food Prot2008，71，： | 1 |
| 10 | Factors that influence the induction dose of propofol显示文摘 | Mecleame GJ Fogarty DF Wattens CH | 1991 | Anaesthesia1991，46，1： | 1 |
| 11 | Simultaneous determinationof ginsenoside Rgl,Re,Rd,Rbl and ophiopogonin D in ratplasma by liquid chromatography/electrosprayionization massspectrometric method and its applicationto pharmacokineticstudy of SHENMAI, injection显示文摘 | Xia CH Wang GJ Sun ]G | 2008 | J Chromatogr B2008，862，2： | 1 |
| 12 | Venousthromboembolism:diagnosis andmanagement of deepvenous thrombosis显示文摘 | Lee CH Hankey GJ Ho WK | 2005 | Med J Aust2005，182，9： | 1 |
| 13 | Out-of-hospital delays in patients with acute stroke 显示文摘 | Rossnagel K Jungehtilsing GJ Nolte CH | 2004 | Ann Emerg Med2004，44，5： | 1 |
| 14 | Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output显示文摘 | Lang CH C Dobrescu GJ Bagby | 1992 | Endocrinology1992，130，1： | 1 |
| 15 | The detection of unknown primary tumors in patients with cervical metastases by dual-head positron emission tomography显示文摘 | Stokkel MP Terhaard CH Hordijk GJ | 1999 | Oral Oncol1999，35，4： | 1 |
| 16 | In vitro drug sensitivity of normal peripheral blood lymphocytes and childhood leukaemic from bone marrow and peripheral blood显示文摘 | KASPERS GJ PIETERS R van ZANTWIJK CH | 1991 | Br J Cancer1991，64，3： | 1 |
| 17 | Factors that influence the induction dose ofpropofol显示文摘 | Mccleane GJ Fogarty DF Watters CH | 1991 | Anaesthesia1991，46，1： | 1 |
| 18 | Pharmacokinetics of the fluocinolone /5-fluorouracil codrug in the gas-filled eye显示文摘 | Perkins SL Gallemore RP Yang CH Guo H Ashton P Jaffe GJ | 2000 | Retina2000，20，： | 1 |
| 19 | Herb-drug interactions:in vivo and in vitro effect of Shenmai injection,a herbal preparation,on the metabolic activities of hepatic cyochrome P450 3A1/2,2C6,1A2,and 2E1 in rats显示文摘 | Xia CH Sun JH Wang GJ | 2010 | Planta Med2010，76，3： | 1 |
| 20 | Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output显示文摘 | Lang CH Dobrescu C Bagby GJ | 1992 | En- docrinology1992，130，1： | 1 |
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