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77篇 您的检索式:作者名="Chiu CW"
    题名 作者 年代 出处 被引量
1Correlation and prognostic significance of beta-galactoside alpha-2,6-sialyltransferase and serum monosialylated alpha-fetoprotein in hepatocellular carcinoma显示文摘AIM: To investigate the correlation between tissue ST6Gal I and serum msAFP in HCC patients, and to investigate their prognostic significance.METHODS: Preoperative sera,paired tumorous and non-tumorous tissues were collected from 19 consecutive patients who had undergone surgical resection of HCC.ST6Gal T activities in the tissues were measured by an in vitro microsomal enzyme activity assay. The percentages of tumor-specific msAFP in the sera were also estimated by an isoelectric focusing-immunoblotting assay.RESULTS: The tumor ST6Gal I activity was negatively correlated with serum msAFP percentage (r = -0.53,P = 0.019). Both decreased tumor ST6Gal I activity andincreased serum msAFP percentage were associatedwith poor tumor cell differentiation. Univariate analyses showed that both decreased tumor ST6Gal T activity (P = 0.028), increased serum msAFP percentage (P = 0.034) and poor tumor cell differentiation (P = 0.031)were associated with shorter overall survival. Multivariate analysis using the Cox regression model showed that the preoperative serum msAFP percentage (P = 0.022)and tumor cell differentiation status (P = 0.048) were independent prognostic indicators for patient overall survival.CONCLUSION: Our results indicate that the presence of msAFP in blood circulation is associated with a decreased activity of ST6Gal I activity in HCC. Both tissue ST6Gal I and serum msAFP are potential prognostic markers for patients with operable HCC.Terence CW Poon Clarissa HS Chiu Paul BS Lai Tony SK Mok Benny Zee Anthony TC Chan Joseph JY Sung Philip J Johnson 2005World Journal of Gastroenterology2005,11,42:4
2Solution structure of the dimerization domain of the eukaryotic stalk P1P2 complex reveals the structural organization of eukaryotic stalk complex显示文摘Lee KM Yu CW Chiu TY 2012Nucleic Acids Res2012,40,7:1
3A comparison of dexmedetomidine and midazolam for sedation in third molar surgery显示文摘CHEUNG CW YING CL CHIU WK et d 2007Anaesthesia2007,62,11:1
4Comparing micellar eletrokineticchromatography and microemulsion electrokinetic chromatographyfor the analysis of preservatives in pharmaceutical and cosmetic products显示文摘Huang HY Lai YC Chiu CW 2003J ChmmatogrA2003,993,:1
5Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia 显示文摘Cheung V Chiu CP Law CW 2011Psychol Med2011,41,8:1
6A randomized clinical trial of TENS and exercise for patients with chronic neck pain显示文摘Chiu TT Hui-Chan CW Chein G 2005Clin Rehabil2005,19,8:1
7Radiofrequency catheter ablation of supraventricular tachycardia in infants and toddlers 显示文摘Chiu SN Lu CW Chang CW 2009Circ J2009,73,9:1
8Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulatiou of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NfkappaB显示文摘Chiu WT Lin YL Chou CW 2009Chem Biol Interact2009,181,3:1
9Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis显示文摘Chiu CW Nozawa H Hanahan D 2010Journal of Clinical Oncology2010,28,29:1
10Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia显示文摘Cheung V Chiu CP Law CW 2010Psychol Med2010,41,8:1
11The role of mechani-cal-electrical interaction in ventricular arrhythmia:evidencefrom a novel animal model for repaired tetralogy of Fallot显示文摘Chiu SN Huang SC Chang CW 201170(3):247-2522011,70,3:1
12Inhibitory effect of gluta- mate release from rat cerebrocortical nerve terminals by α2 adrenoeeptor agonist dexmedetomidine 显示文摘Chiu KM Lin TY Lu CW 2011Enr J Pharmacol2011,670,1:1
13Inhibitory effect of gluta- mate release from rat eerebrocortieal nerve terminals by a 2 adrenoceptor agonist dexmedetomidine 显示文摘Chiu KM Lin TY Lu CW 2011Eur J Ph- ramcol2011,670,1:1
14Fundamental techniques for resolution en- hancement of average subsampled images 显示文摘Shen DF Chiu CW 2012Journal of Elec- tronic Imaging2012,21,3:1
15Proteomics analysis of EV71-infected cells reveals the involvement of host protein NEDD4L in EV71 replication 显示文摘Kuo RL Lin YH Wang RY Hsu CW Chiu YT Huang HI Kao LT Yu JS Shih SR Wu CC 2015J Proteome Res2015,14,4:1
16Inhibitory effect of glutamate re- lease from rat cerebrocortical nerve terminals by alpha2 adrenocep- tor agonist dexmedetomidine 显示文摘Chiu KM Lin TY Lu CW 2011Eur J Pharmacol2011,670,1:1
17Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals byα2adrenoceptor agonist dexmedetomidine显示文摘Chiu KM Lin TY Lu CW 2011Eur J Pharmacol2011,670,1:1
18Simvastatin increases serum osteocalcin concentration in patients treated for hypercholesterolaemia显示文摘Chan MH Mak TW Chiu RW Chow CC Chan IH Lam CW 0,,:1
19Inhibitory effect of glutamate release from rat crerbrocortical nerve terminals by 02 adrenoceptor agonist dexmedetomidine显示文摘Chiu KM Lin TY Lu CW 2011European Journal of Pharmacology2011,670,1:1
20Analysis of food colorants by capillary electrophoresis with large-volume sample stacking显示文摘Huang HY Chiu CW Sue SL 2003J Chromatogr A2003,995,12:1
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