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1Systematic review of the outcomes of surgical resection for intermediate and advanced Barcelona Clinic Liver Cancer stage hepatocellular carcinoma:A critical appraisal of the evidence显示文摘AIM To perform a systematic review to determine the survival outcomes after curative resection of intermediate and advanced hepatocellular carcinomas(HCC).METHODS A systematic review of the published literature was performed using the PubM ed database from 1 st January 1999 to 31 st Dec 2014 to identify studies that reported outcomes of liver resection as the primary curative treatment for Barcelona Clinic Liver Cancer(BCLC) stage B or C HCC. The primary end point was to determine the overall survival(OS) and disease free survival(DFS) of liver resection of HCC in BCLC stage B or C in patients with adequate liver reserve(i.e., Child's A or B status). The secondary end points were to assess the morbidity and mortality of liver resection in large HCC(defined as lesions larger than 10 cm in diameter) and to compare the OS and DFS after surgical resection of solitary vs multifocal HCC.RESULTS We identified 74 articles which met the inclusion criteria and were analyzed in this systematic review. Analysis of the resection outcomes of the included studies were grouped according to(1) BCLC stage B or C HCC,(2) Size of HCC and(3) multifocal tumors. The median 5-year OS of BCLC stage B was 38.7%(range 10.0-57.0); while the median 5-year OS of BCLC stage C was 20.0%(range 0.0-42.0). The collective median 5-year OS of both stages was 27.9%(0.0-57.0). In examining the morbidity and mortality following liver resection in large HCC, the pooled RR for morbidity [RR(95%CI) = 1.00(0.76-1.31)] and mortality [RR(95%CI) = 1.15(0.73-1.80)] were not significant. Within the spectrum of BCLC B and C lesions, tumors greater than 10 cm were reported to have median 5-year OS of 33.0% and multifocal lesions 54.0%.CONCLUSION Indication for surgical resection should be extended to BCLC stage B lesions in selected patients. Further studies are needed to stratify stage C lesions for resection.Ye Xin Koh Hwee Leong Tan Weng Kit Lye Juinn Huar Kam Adrian Kah Heng Chiow Siong San Tan Su Pin Choo Alexander Yaw Fui Chung Brian Kim Poh Goh 2018World Journal of Hepatology2018,10,6:10
2Discrete element method study of shear-driven granular segregation in a slowly rotating horizontal drum显示文摘Ram Chand Sithi V. Muniandy Chiow San Wong Jasbir Singh 2017Particuology2017,15,3:4
3VIBEX : an expert system for vibration fault diagnosis of rotating machinery using decision tree anti decision table 显示文摘Yang Bo-Suk Lim Dong-Soo Tan An(Iv Chit Chiow 2005Expert Systems with Applications2005,28,:1
4A new photon recoil experiment: towards a determination of the fine structure constant显示文摘H. Müller S.-W. Chiow Q. Long C. Vo S. Chu 2006Applied Physics B2006,,4:1
5VIBEX: an expert system for vibration fault diagnosis of rotating machinery using decision tree and decision table显示文摘YANG BoSuk Lin DongSoo & Tan Andy Chit Chiow 2005Expert Systems With Applications2005,28,4:1
6102 k Large Area Atom Interferometers 显示文摘CHIOW SHENG-WEY KOVACHY TIM CHIEN HUI-CHUN 2011Phys Rev Lett2011,107,13:1
7Multi-agent decision fusion for motor fault diagnosis显示文摘Gang Niu Tian Han Bo-Suk Yang Andy Chit Chiow Tan 2006Mechanical Systems and Signal Processing2006,,3:1
8An Expert System for Vibration Fault Diagnosis of Rotating Machinery Us- ing Decision Tree and Decision Table显示文摘Bo-Suk Yang Dong-Soo Lim Andy chit chiow Tan 2005Expert Systems with Applications2005,12,:1
9Does the laparoscopic approach for liver resections for colorectal liver metastasis truly confer improved survival outcomes?显示文摘As an increasing proportion of surgeons mount their learning curves in laparoscopic liver resections,a larger percentage of liver surgery is being performed laparoscopically(1).Syn et al.(2)published an impressive statistical analysis of existing randomized controlled trials(RCT)and propensity-score matched(PSM)studies that model a long-term survival benefit in favor of laparoscopic over open resection for colorectal liver metastases(CRLM).Whilst this is an encouraging outcome,it is critical to analyze the studies included that led to these improved survival outcomes.Nita Thiruchelvam David Cavallucci Adrian Kah Heng Chiow 2020Hepatobiliary Surgery and Nutrition2020,9,6:0
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