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| 1 | 澳大利亚临床共识指南:儿童卒中的诊断和急性期处理显示文摘卒中是导致儿童死亡的十大原因之一,幸存的致残患儿将面临几十年的残疾生活,给患儿及其家庭带来了巨大负担。由于安全性和有效性的证据有限,以及诊断的延误,目前卒中患儿无法接受再灌注治疗。儿童卒中诊断和急性期处理的澳大利亚临床共识指南,旨在最大限度地减少临床诊疗中的不确定性,并记录与成人卒中不同的危险因素、病因和假性卒中情况的最佳证据。临床问题的阐述来自于对2007年至2017年数据库的系统检索,但仅限于英语和儿科研究。该指南应用SIGN方法和国家健康与医学研究委员会系统对证据进行筛选和分类,通过推荐、评估、发展和评价系统(GRADE系统)对推荐进行强弱分级。该指南提供了60多项基于证据的推荐,以帮助参与院前和急症处理的临床医师快速识别儿童卒中,选择最合适的初步检查方案来确定诊断、明确病因,并选择最恰当的干预措施以挽救脑组织、预防复发。同时,指南也提供了颅内压和先天性心脏病管理方面的推荐。该指南的实施需要将院前和急诊系统重组,包括建立区域性卒中网络,建立儿科卒中疾病编码,快速MRI,以及对能够提供再灌注治疗的初级儿科卒中中心进行认证。该指南能够审核治疗的基准时间线,获得急性期的干预措施及预后判断。它还将促进澳大利亚儿童卒中登记的发展,并与国际登记处建立数据联系,以便准确收集卒中发病率、治疗和结果相关的数据。 | Medley TL Miteff C Andrews I Ware T Cheung M Monagle P Mandelstam S Wray A Pridmore C Troedson C Dale RC Fahey M Sinclair A Walsh P Stojanovski S Macka MT 徐佳丽(译) 吴川杰(译) 肖潇(译) 吕俊萱(译) 张博维(译) 吉训明(译) | 2019 | 中国脑血管病杂志2019，16，4： | 9 |
| 2 | 儿童期肥胖、成年期肥胖和心血管风险因子显示文摘过去30年,儿童超重或肥胖的发生率明显增加[1]。儿童期肥胖是死亡率增加的预测因子,这主要是由于儿童期肥胖可导致心血管疾病发生率增加。相关的预测研究提示"肥胖流行症"可能改变目前心血管疾病死亡率下降的趋势,使现今儿童的寿命缩短。 | Juonala M Magnussen CG Berenson GS Venn A Burns TL Sabin MA Srinivasan SR Daniels SR Davis PH Chen W Sun C Cheung M Viikari JS Dwyer T Raitakari OT 叶鹏 | 2012 | 中华高血压杂志2012，20，1： | 6 |
| 3 | Ammonia stripping as a pretreatment for landfill leachate显示文摘 | Cheung K C Chu L M Wong M H | 1997 | Water Air and Soil Pollution1997，94，： | 2 |
| 4 | Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes显示文摘The term 'neurodevelopmental disorder' broadly encompasses conditions thought to arise early in development and includes schizophrenia, bipolar disorder and autism among others. These conditions share a number of genetic and environmental risk factors postulated to lead to common difficulties in socio-emotional processing, communication and cognitive function. The alternative position is that, while the same traits are affected across these conditions, the nature or direction in which they are modified may be distinct. MRI studies provide a rapidly expanding and rich database which we propose can be used to contribute to this debate. Anatomical likelihood estimation (ALE) is a method of meta-analysis applied to voxel-based MRI studies. We have adapted this method to explore the extent to which schizophrenia and bipolar disorder and schizophrenia and autism share a common brain structural phenotype. We will review this work here and discuss whether there is sufficient other evidence to justify a common framework for further research into the inter-relatedness of such conditions. | MCALONAN Grainne M YU Kevin K CHAN Raymond C K CHUA Siew E CHEUNG Charlton | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 5 | RAC/ROP GTPases:hubs for signal integration and diversification in plants显示文摘 | Nibau C Wu H M Cheung A Y | 2006 | Trends Plant Sci2006，11，： | 1 |
| 6 | Pollutants in Hong Kong soils: Potycyclic aromatic hydrocarbons显示文摘 | CHUNG M K HU R CHEUNG K C | 2007 | Chemosphere2007，67，3： | 1 |
| 7 | Relationshipsbetween tissue concentrations of polycyclic aromatic hydro-carbons and antioxidative responses of marine musselsPerna viridis显示文摘 | Cheung C C C Zheng G J Li A M Y | 2001 | Aquatic Toxicology2001，52，34： | 1 |
| 8 | A prospective randomized controlled trial on ureteral stenting after ureteroscopic holmium laser lithotripsy显示文摘 | CHEUNG M C LEE F LEUNG Y L | 2003 | J Urol2003，169，4： | 1 |
| 9 | Regulation of exoprotein expression in Staphylococcus aureus by a locus (sat) distinct from agr显示文摘 | Cheung A L Koomey J M Butler C A | 1992 | Proc Natl Acad Sci1992，89，： | 1 |
| 10 | Retinal micro-vasculature as a model to study the manifestations of hyperten- sion显示文摘 | Cheung C Y Ikram M K Sabanayagam C | 2012 | Hypertension2012，60，5： | 1 |
| 11 | , manipulation of insulin-like growth factor binding protein-3 levels显示文摘 | CHEUNG C W TAYLOR P J KIRKPATRICK C M et aL Therapeutic value of orally administered silibinin in renal cell carcinoma | 2007 | Br J Urol Inter2007，100，2： | 1 |
| 12 | Carbene and isocya- nide ligation at luminescent eyclometalated 6-phenyl-2,2-bipyr- idyl platinum ( Ⅱ ) complexesStruetural and spectroseopic显示文摘 | Lai S W Chan M C W Cheung K K | 1999 | Organometallics1999，18，17： | 1 |
| 13 | The cyp2e1-humanized transgenic mouse:role of cyp2e1 in acetaminophen hepatotoxicity显示文摘 | CHEUNG C YU A M WARD J M | 2005 | Drug Metab Dispos2005，33，3： | 1 |
| 14 | Knowledge - based Treatment Planning for Adolescent Early Intervention of Mental Healthcare : A Hybrid Case - based Reasoning Approach 显示文摘 | Wang W M Cheung C F | 2007 | Expert System2007，24，4： | 1 |
| 15 | A theoretical model of intentional social action in online social networks 显示文摘 | Cheung C M K Lee M K O | 2010 | Decision Support Systems2010，49，1： | 1 |
| 16 | Composition and genetic diversity of picoeukaryotes in subtropical coastal waters as revealed by 454 pyrosequencing 显示文摘 | Cheung M K Au C H Chu K H | 2010 | The ISME Journal2010，4，8： | 1 |
| 17 | Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice显示文摘 | Cheung C Yu A M Chen C S | 2006 | J Pharmacol Exp Ther2006，316，3： | 1 |
| 18 | Adaptive motion tracking block matching algorithms for video coding显示文摘 | XU J B PO L M CHEUNG C K | 1999 | IEEE Trans on Circuits and System for Video Technology1999，9，7： | 1 |
| 19 | The Utility of the Revised Life Orientation Test to Measure Optimism among Hong Kong Chinese显示文摘 | Lai J C L Cheung H Lee W M | 1998 | International Journal of Psychology1998，33，1： | 1 |
| 20 | Effects of fish protein hydrolysate and freeze-thaw treatment on physicochemical and gel properties of natural actomyosin from Pacific cod显示文摘 | KORZENIOWSKA M CHEUNG I W Y LI-CHAN E C Y | 2013 | Food Chemistry2013，138，2： | 1 |
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