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| 1 | Microstructure and Properties of Low Temperature Composite Chromized Layer on H13 Tool Steel显示文摘Low temperature composite chromizing is a process composed of a plain ion-carbonitriding or ion-nitriding at 550~580℃, followed by a low-temperature chromizing in a salt-bath of 590℃. The microstructure and properties of the low temperature composite chromized layer on H13 tool steel were investigated using metallography,X-ray diffraction, microanalysis, hardness and wear tests. It was found that this low temperature process was thermodynamically and kinetically possible, and the composite chromized layer on H13 steel, with a thickness of 3~6μm,consisted of three sub-layers (bands), viz. the outer Cr-rich one, the intermediate (black) one, and the inner, original white layer. After chromizing, the former diffusion layer was thickened. The results of X-ray diffraction showed that the composite chromized layer contained such nitrides and carbides of chromium as CrN, Cr2N, (Cr, Fe)23C6, and (Cr, Fe)7C3, as well as plain α-(Fe, Cr). A high surface microhardness of 1450~1550 HV0.025, which is much higher than that obtained by the conventional ion carbonitriding and ion nitriding, was obtained. In addition, an excellent wear resistance was gained on the composite chromized layer. | Cuilan WU, Chengping LUO and Ganfeng ZOU College of Mechanical Engineering, South China University of Technology, Guangzhou 510641, China | 2005 | Journal of Materials Science & Technology2005，21，2： | 9 |
| 2 | Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study显示文摘 | Caicun Zhou Yi-Long Wu Gongyan Chen Jifeng Feng Xiao-Qing Liu Changli Wang Shucai Zhang Jie Wang Songwen Zhou Shengxiang Ren Shun Lu Li Zhang Chengping Hu Chunhong Hu Yi Luo Lei Chen Ming Ye Jianan Huang Xiuyi Zhi Yiping Zhang Qingyu Xiu Jun Ma Li Zhang C | 2011 | Lancet Oncology2011，，8： | 7 |
| 3 | A Novel Duplex Low-temperature Chromizing Process at 500℃显示文摘在 500 °C 的一个优化低温度的渗铬过程经由由先锋血浆 nitriding 组成的一个双渗铬过程与 0.45 wt %碳在平凡的中等碳的钢上被认识到,并且跟随的盐洗澡 thermoreactive 免职和散开( TRD )有薄散开层的渗铬 process.CrN 层在下面被形成。双渗铬过程被光显微镜学(OM ) 学习,扫描电子显微镜学(SEM ) ,精力散 X 光检查光谱学(版本) , X 光检查衍射(XRD ) ,和传播电子显微镜学(TEM ) 。在 500 °C 的渗铬速度被增加更多的 Cr-Fe 粉末进盐洗澡成功地提高,这被发现,并且 CrN 层在厚度与一般水准 8.1 亩 m 以优先的氮化物混合物 layer.A CrN 层的成本形成了,在微坚硬的 1382 HV_( 0.01 )被双渗铬更为 24 h.Further 在 500 °C 在底层上形成, CrN 层由 nanocrystalline CrN 谷物组成了。 | Huiliang CAO Cuilan WU Jiangwen LIU Chengping LUO Ganfeng ZOU | 2007 | Journal of Materials Science & Technology2007，23，6： | 3 |
| 4 | Effect of molybdenum on diamond deposition and adhesion显示文摘 | Huang Yuansheng Qiu Wanqi Luo Chengping | 2005 | Thin Solid Films2005，472，： | 1 |
| 5 | Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study显示文摘 | Caicun Zhou Yi-Long Wu Gongyan Chen Jifeng Feng Xiao-Qing Liu Changli Wang Shucai Zhang Jie Wang Songwen Zhou Shengxiang Ren Shun Lu Li Zhang Chengping Hu Chunhong Hu Yi Luo Lei Chen Ming Ye Jianan Huang Xiuyi Zhi Yiping Zhang Qingyu Xiu Jun Ma Li Zhang C | 2011 | Lancet Oncology2011，，8： | 1 |
| 6 | Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study显示文摘 | Caicun Zhou Yi-Long Wu Gongyan Chen Jifeng Feng Xiao-Qing Liu Changli Wang Shucai Zhang Jie Wang Songwen Zhou Shengxiang Ren Shun Lu Li Zhang Chengping Hu Chunhong Hu Yi Luo Lei Chen Ming Ye Jianan Huang Xiuyi Zhi Yiping Zhang Qingyu Xiu Jun Ma Li Zhang C | 2011 | Lancet Oncology2011，，8： | 1 |
| 7 | Fabrication and microstructure of in situ Al2O3 decomposed from Al2(SO4)3-reinforced aluminum matrix composites 显示文摘 | Ouyang Liuzhang Luo Chengping Sui Xiandong | 2002 | Materials Letters2002，57，： | 1 |
| 8 | 显示文摘 | Chen Xianming Luo Chengping Liu Jiangwen | 2010 | Journal of Functional Materials2010，41，12： | 1 |
| 9 | Effect of molybdenum on diamond deposition and adhesion 显示文摘 | Huang Yuansheng Qiu Wanqi Luo Chengping | 2005 | Thin Solid Films2005，472，12： | 1 |
| 10 | Study on the formation mechanism of micro-arc oxidation coatings on magnesium显示文摘 | Chen Xianming Luo Chengping Liu Jiangwen | 2010 | Alloys Materials Science Forum2010，650，： | 1 |
| 11 | Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study显示文摘 | Caicun Zhou Yi-Long Wu Gongyan Chen Jifeng Feng Xiao-Qing Liu Changli Wang Shucai Zhang Jie Wang Songwen Zhou Shengxiang Ren Shun Lu Li Zhang Chengping Hu Chunhong Hu Yi Luo Lei Chen Ming Ye Jianan Huang Xiuyi Zhi Yiping Zhang Qingyu Xiu Jun Ma Li Zhang C | 2011 | Lancet Oncology2011，，8： | 1 |
| 12 | Effect of molybdenum on diamond deposition and adhesion显示文摘 | Huang Yuansheng Qiu Wanqi Luo Chengping | 2005 | Thin Solid Films2005，472，12： | 1 |
| 13 | MORPHOLOGY AND CRYSTALLOGRAPHY OF ALLOY NITRIDES IN STEEL 4Cr5MoV1Si(H13)显示文摘A TEM investigation was made on the morphology,orientation relationship and habit plane ofthree alloy nitrides,namely CrN,VN and Mo2N simultaneously formed within thediffussional nitrided layers in an H13 steel nitrided at 580℃.It was.found that the nitrideswere precipitated by continuous clustering and subsequent ordering of both interstitial(N)andsubstitutional(Cr,V,Mo)solutes on {001} habit plane,and that the observed morphologyand crystallography of the nitrides were in good agreement with the predictions from theinvariant line stain model proposed for precipitation transformations. | LUO Chengping(C.P.Luo) ZHAO Fang South China University of Technology,Guangzhou,China | 1991 | Acta Metallurgica Sinica(English Letters)1991，4，3： | 0 |
| 14 | B1-cell-produced anti-phosphatidylserine antibodies contribute to lupus nephritis development via TLR-mediated Syk activation显示文摘Autoantibodies produced by B cells play a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE). However, both the cellular source of antiphospholipid antibodies and their contributions to the development of lupus nephritis (LN) remain largely unclear. Here, we report a pathogenic role of anti-phosphatidylserine (PS) autoantibodies in the development of LN. Elevated serum PS-specific IgG levels were measured in model mice and SLE patients, especially in those with LN. PS-specific IgG accumulation was found in the kidney biopsies of LN patients. Both transfer of SLE PS-specific IgG and PS immunization triggered lupus-like glomerular immune complex deposition in recipient mice. ELISPOT analysis identified B1a cells as the main cell type that secretes PS-specific IgG in both lupus model mice and patients. Adoptive transfer of PS-specific B1a cells accelerated the PS-specific autoimmune response and renal damage in recipient lupus model mice, whereas depletion of B1a cells attenuated lupus progression. In culture, PS-specific B1a cells were significantly expanded upon treatment with chromatin components, while blockade of TLR signal cascades by DNase I digestion and inhibitory ODN 2088 or R406 treatment profoundly abrogated chromatin-induced PS-specific IgG secretion by lupus B1a cells. Thus, our study has demonstrated that the anti-PS autoantibodies produced by B1 cells contribute to lupus nephritis development. Our findings that blockade of the TLR/Syk signaling cascade inhibits PS-specific B1-cell expansion provide new insights into lupus pathogenesis and may facilitate the development of novel therapeutic targets for the treatment of LN in SLE. | Kongyang Ma Wenhan Du Shiyun Wang Fan Xiao Jingyi Li Jie Tian Yida Xing Xiaodan Kong Ke Rui Rencai Qin Xiaoxia Zhu Jing Wang Cainan Luo Haijing Wu Yun Zhang Chengping Wen Lan He Dongzhou Liu Hejian Zou Qianjin Lu Lijun Wu Liwei Lu | 2023 | Cellular & Molecular Immunology2023，20，8： | 0 |
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