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| 1 | A study of preoperative methionine-depleting parenteral nutrition plus chemotherapy in gastric cancer patients显示文摘AIM To investigate the interference ofmethionine.free parenteral nutrition plus 5-Fu(-MetTPN+5-Fu)in gastric cancer cell kineticsand the side effects of the regimen.METHODS Fifteen patients with advancedgastric cancer were randomly divided into twogroups,7 patients were given preoperatively aseven-day course of standard parenteralnutrition in combination with a five-day courseof chemotherapy(sTPN+5-Fu),while the other8 patients were given methionine-deprivedparenteral nutrition and 5-Fu(-MetTPN+5-Fu).Cell cycles of gastric cancer and normal mucosawere studied by flow cytometry(FCM).Bloodsamples were taken to measure the serumprotein,methionine(Met)and cysteine(Cys)levels,and liver and kidney functions.RESULTS As compared with the resultsobtained before the treatment,the percentage ofG0/G1 tumor cells increased and that of S phasedecreased in the-MetTPN+5-Fu group,while thecontrary was observed in the sTPN+5-Fu group.Except that the ALT,AST and AKP levels wereslightly increased in a few cases receiving-MetTPN+5-Fu,all the other biochemicalparameters were within normal limits.Serum Cys level decreased slightly after the treatmentin both groups.Serum Met level of patientsreceiving sTPN+5-Fu was somewhat higher aftertreatment than that before treatment;however,no significant change occurred in the -MetTPN+5-Fu group,nor operative complications in bothgroups.CONCLUSION -MetTPN+5-Fu exerted asuppressive effect on cancer cell proliferation,probably through a double mechanism ofcreating a state of'Met starvation'adverse tothe tumor cell cycle,and by allowing 5-Fu to killspecifically cells in S phase.Preoperative short-term administration of -MetTPN+5-Fu had littleundesirable effect on host metabolism. | Cao WX Cheng QM Fei XF Li SF Yin HR Lin YZ | 2000 | World Journal of Gastroenterology2000，6，2： | 22 |
| 2 | Effects of psychological nursing intervention on personality characteristics and quality oflife of patients with esophageal cancer显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clin Res Hepatol Gastroenterol2013，37，3： | 1 |
| 3 | Magmatic hydrothermal superlarge metallogenic systems-a case study of the Nannihu ore field 显示文摘 | Wang CM Cheng QM Zhang ST | 2008 | Journal of China University of Geoseiences2008，19，： | 1 |
| 4 | Enteric nervous system,interstitial cells of cajal,and smooth muscle vacuolization in segmental dilatation of jejunum显示文摘 | Lui VCH Chen QM | 2001 | J Pediatr Surg2001，36，6： | 1 |
| 5 | Effects of psychological nursing in- tervention on personality characteristics and quality of life of patients with esophageal cancer显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clin Res Hepatol Gastroenterol2013，37，3： | 1 |
| 6 | Effects of psychological nursing intervention on personality characteristics and quality of life of patients with esophageal cancer显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clinics and research in hepatology and gastroenterology2013，37，3： | 1 |
| 7 | Effects of psychological nurs- ing intervention on personality characteristics and quality of life of patients withesophageal cancer显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clin Res Hepatol Gastroenterol2013，37，3： | 1 |
| 8 | Substrate specificity of the AmpG permease required for recycling of cell wall anhydro-muropeptides显示文摘 | Cheng QM ParkJT | 2002 | Journal of Bacteriology2002，184，23： | 1 |
| 9 | Effects of psychological nursing intervention on personality characteristics and quality of life of patients with esophageal cancer 显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clin Res Hepatol Gastroen- terol2013，37，3： | 1 |
| 10 | Effects of psychological nurs- ing intervention on personality characteristics and quality of life of pa- tients with esophageal cancer 显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clin Res Hepatroenterol2013，37，3： | 1 |
| 11 | Good multifractal modeling of fractures in the Lac Du Bonnet Botholith,Manitoba显示文摘 | Agterberg F P Cheng QM Brown A | 1996 | Computers & Geosciences1996，22，5： | 1 |
| 12 | Effects of psychological nursing?intervention on personality characteristics and quality of life of patients with esophageal cancer显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clin Res Hepatol Gastroenterol2013，37，： | 1 |
| 13 | the separation of geochemical anomalies from background by fractal methods显示文摘 | Cheng QM Agterberg FP Ballantyne SB | 1994 | Journal of geochemical exploration1994，51，2： | 1 |
| 14 | Fractal geometry of element distribution on mineral surfaces显示文摘 | Zheng Z Mao H Cheng QM | 2001 | mathematical of geology2001，33，2： | 1 |
| 15 | Effects of psychological nursing intervention on personality characteristics and quality of life of patients with esophageal cancer显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clin Res Hepatol Gastroenterol2013，37，3： | 1 |
| 16 | Effects of psycho- logical nursing intervention on personality characteristics and quality of life of patients with esophageal cancer显示文摘 | Cheng QM Kong CQ Chang SY | 2013 | Clin Res Hepatol Gastroenterol2013，37，3： | 1 |
| 17 | Evaluation of ZnO Nanorod Arrays with Dandelion-Like Morphology as Negative Electrodes for Lithium-Ion Batteries 显示文摘 | Wang HB Pan QM Cheng YX | 2009 | ElectrochimicaActa2009，54，： | 1 |
| 18 | Effects of psychological nursing intervention on personality characteristics and quality of life of patients with esophageal cancer显示文摘 | Cheng QM Kong CQ Chang SY | | 0，，03： | 1 |
| 19 | Ferroelectric and electro-mechanical properties of poly(vinylidene-fluoride-trifluoroethylene-chlorotrifluoro-ethylene) terpolymer显示文摘 | Xu H Cheng Z-Y Olson D Mai T Zhang QM Kavarnos | 2001 | Appl Phys Lett2001，78，22： | 1 |
| 20 | Corticosteroids for fat embolism after multiple fractures显示文摘 | CHENG HS ZHANG QM WEN JM | 2007 | Chin J Traumatol2007，10，3： | 1 |
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