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| 1 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005，，19： | 6 |
| 2 | Anti-N-methyl-D-aspartate receptor encephalitis that aggravates after acinetobacter baumannii pneumonia:A case report显示文摘We report an atypical case of anti-N-methyl-D-aspartate receptor encephalitis(ANMDARE). A 27-year-old man diagnosed with ANMDARE received immunotherapy and had a good recovery. However, within one month, he developed severe status epilepticus and decreased level of conscience with new hyperpyrexia and dyspnea, and was admitted to the emergency intensive care unit. Acinetobacter baumanii were found in the sputum culture; and anti-NMDAR antibodies were positive(titer: 1/80) in the cerebrospinal fluid. Repeated immunotherapy was administered with antibacterial agents, and the patient recovered except for mild psychiatric sequelae. This is the first report of ANMDARE that aggravates after acinetobacter baumannii pneumonia. Awareness and knowledge of this disorder should be extended, especially in the emergency medicine community. | Cheng C Wang Da J Li Yi Q Xia Kai Liu | 2017 | World Journal of Clinical Cases2017，5，9： | 3 |
| 3 | Single machine scheduling with deadlines and increasing rates of processing times显示文摘 | Cheng T C E Ding Q | 2000 | Acta Informatica2000，36，910： | 2 |
| 4 | Effects of the phase-separated melt on crystallization behavior and morphology in short chain branched metallocene polyethylenes显示文摘 | Fu Q Chiu F C McCreight K W Guo M Tseng W W Cheng S Z Keating M Y Hsieh E T and DesLauriers P J | | 0，，： | 2 |
| 5 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，： | 1 |
| 6 | NF-κB is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells显示文摘 | Howard E F Chen Q Cheng C | 1998 | Neurosci Lett1998，248，3： | 1 |
| 7 | Inequalities for eigenvalues of a clamped plate problem显示文摘 | Cheng Q M Yang H C | 2006 | Trans Amer Math Soc2006，358，6： | 1 |
| 8 | Effects of ECAE process on microstructure and transformation behavior of TiNi shape memory alloy 显示文摘 | LI Z H XIANG C Q CHENG X H | 2006 | Materials and Design2006，27，4： | 1 |
| 9 | Oral administration of exopolysaccharide from Aphanothece halophytica (Chroo coecales) significantly inhibits influenza virus (H1N1)-in- duced pneumonia in mice 显示文摘 | Zheng W Chen C Cheng Q | 2006 | Int Immunopharmacol2006，6，： | 1 |
| 10 | Hydrogen storage in carbon nanotubes显示文摘 | Cheng H M Yang Q H Liu C | 2001 | Carbon2001，39，10： | 1 |
| 11 | ANew Way to Calculate Radiative Intensity and Solve Radiative Transfer Equation through Using the Monte Carlo Method 显示文摘 | ZHOU H C CHEN D L CHENG Q | 2004 | JQSRT2004，，83： | 1 |
| 12 | Transgenic rice with a synthetic crylAb gene from Bacillus thuringiensis is highly resistant to eight lepidopteran insects显示文摘 | Shu Q Y Ye G Y Cui H R Cheng X Xiang Y Wu D Gao M Xia Y Hu C Sardana R Altosaar I | 2000 | Mol Breed2000，，6： | 1 |
| 13 | Co and Fe-based multi-component bulk metallic glasses designed by cluster line and minor-alloying 显示文摘 | Wang Q Cheng X Zhu C L | 2007 | J Mater Res2007，，： | 1 |
| 14 | Synthesis and characterization of carbon-coated LiNil/3Col/3Mnl/3Oz cathode material prepared by polyvinyl alcohol pyrolysis route 显示文摘 | GUO R SHIP F CHENG X Q DU C Y | 2009 | Journal of Alloys and Compounds2009，473，： | 1 |
| 15 | The bounded single-machine parallel-batching schedulingproblem with family jobs and release dates to minimize makespan显示文摘 | Nong Q Q Ng C T and Cheng T C E | 2008 | Operations Research Letters2008，，111： | 1 |
| 16 | Lectin-Based Nanoprobes Functionalized with Enzyme for Highly Sensitive Electrochemical Monitoring of Dynamic Carbohydrate Expression on Living Cells显示文摘 | Ding L Ji Q J Qian R C Cheng W Ju H X | | 0，，04： | 1 |
| 17 | Increasing the visible light absorption of graphitic carbon nitride(melon)photocatalysts by homogeneous self-modification with nitrogen vacancies显示文摘 | Niu P Yin L C Yang Y Q Liu G Cheng H M | 2014 | Advanced Materials2014，26，47： | 1 |
| 18 | Electroki- netic remediation and its combined technologies for re- moval of organic pollutants from contaminated soils 显示文摘 | Huang D Xu Q Cheng J Lu X C Zh H | 2012 | International Journal of Electrochemical Science2012，7，： | 1 |
| 19 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，： | 1 |
| 20 | Autophagy gene-dependent clearance of apoptotic cells during embryonic development显示文摘 | Qu X Zou Z Sun Q Luby-Phelps K Cheng P Hogan RN Gilpin C Levine B | 2007 | Cell2007，128，5： | 1 |
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