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| 1 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 2 | Genetic transformation of wheat mediated by Agrobacterium tumefaciens显示文摘 | Cheng M Fry J E Pang S Zhou H Hironaka C M Duncan D R Conner T W Wan Y | 1997 | Plant Physiol1997，，： | 2 |
| 3 | Effect of saikosaponin, a triterpene saponin, on apoptosis in lymphocytes: association with c-myc, p53, and bc1-2 mRNA 显示文摘 | Hsu M J Cheng J S Huang H C | 2000 | Br J Pharmacol2000，131，7： | 2 |
| 4 | Telomerase activity in pleural effusions diagnostic significance显示文摘 | CHENG T Y LEE M H LAN R S | 1998 | J Clin Oncol1998，16，4： | 2 |
| 5 | Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor - induced angiogenesis显示文摘 | Cheng N Brantley D M Liu H | 2002 | Mol Cancer Res2002，1，1： | 1 |
| 6 | Damage-based formability analysis for TWBs显示文摘 | Cheng C H Jie M | 2005 | International Journal of Damage Mechanics2005，14，1： | 1 |
| 7 | Inequalities for eigenvalues of a clamped plate problem显示文摘 | Cheng Q M Yang H C | 2006 | Trans Amer Math Soc2006，358，6： | 1 |
| 8 | Northward migration of Helicoverpa armigera and Other motha in early summer observedwith radar in Northern China显示文摘 | Feng H Q Wu K M Cheng D F | 2004 | Journal of Economic Entomology2004，97，6： | 1 |
| 9 | Airborne hyperspectral imagery and linear spectral unmixing for mapping variation in corp yield显示文摘 | Cheng hai Yang James H Everitt Joe M Bradford | 2007 | Precision Agric2007，8，： | 1 |
| 10 | Genetic analysis of a novel dominant rice dwarf mutant 986083D显示文摘 | Qin R Z Qiu Y Cheng Z J Shan X Y Guo X P Zhai H Q Wan J M | 2008 | Euphytica2008，160，： | 1 |
| 11 | Direct observation of short-circuit diffusion during the formation of a single cupric oxide nanowire显示文摘 | Cheng C L Ma Y R Chou M H | 2007 | Nanotechnology2007，18，24： | 1 |
| 12 | Range-based sleep scheduling (RBSS) for wireless sensor networks显示文摘 | YEN L H CHENG Y M | 2009 | Wireless Personal Communications2009，48，3： | 1 |
| 13 | Radar observations of the autumn migration of the beet armyworm Spodoptera exigua (Lepidoptera: Noctuidae) and other moths in northern China显示文摘 | Feng H Q Wu K M Cheng D F | 2003 | Bull Entomol Res2003，93，2： | 1 |
| 14 | Characteristics, apa tire-forming ability and corrosion resistance of NiTi surface modified by AC anodization 显示文摘 | WONG M H CHENG F T MAN H C | 2007 | Appl Surface Sci2007，253，18： | 1 |
| 15 | Benign lymphoepithelial lesion of minor salivary gland:report of a case involving the palatal mucosa显示文摘 | Metwaly H Cheng J Suzuki M | 2004 | Oral Oncol Extra2004，40，10： | 1 |
| 16 | Graphitization behavior of wood ceramics and bamboo ceramics as determined by X-Ray diffraction显示文摘 | Cheng H M | 1999 | Journal of Porous Materials1999，6，： | 1 |
| 17 | Complexities for generalized models of self-assembly显示文摘 | Aggarwal G Cheng Q Goldwasser M H | 2005 | SIAM Journal on Computing2005，34，14： | 1 |
| 18 | Monitoring process mean and variability with one EWMA chart 显示文摘 | Chen G M Cheng S W Xie H S | 2001 | Journal of Quality Technology2001，33，2： | 1 |
| 19 | Cultivation of Acetobacter xylinum for bacterial cellulose production in a modified airlift reactor显示文摘 | Cheng H P Wang P M Chen J W | 2002 | Biotechnology and Applied Biochemistry2002，35，2： | 1 |
| 20 | Fully Functionalized High-dielectric Nanophase Polymers with High Electromechanical Response显示文摘 | Cheng H Zhang Q M | 2005 | Advanced Materials2005，，17： | 1 |
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