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139篇 您的检索式:作者名="Chen Weiqiang"
    题名 作者 年代 出处 被引量
1Prognostic factors of refractory NSCLC patients receiving anlotinib hydrochloride as the third-or further-line treatment显示文摘Objective:Anlotinib hydrochloride is a multitarget tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor,fibroblast growth factor receptor,platelet-derived growth factor receptor,c-Kit,and c-MET;therefore,it exhibits both antitumor and anti-angiogenetic activities.A phase III trial has shown that anlotinib improved progression-free survival(PFS)and overall survival(OS)in patients with advanced non-small cell lung cancer(NSCLC),who presented with progressive disease or intolerance after standard chemotherapy.This study aimed to analyze the characteristics of patients receiving anlotinib treatment to determine the dominant populations who are fit for the treatment.Methods:Data were collected from March 2015 to January 2017 from a randomized,double-blind,placebo-controlled,multicenter,phase III trial of anlotinib(ALTER0303).A total of 437 patients were enrolled and randomly allocated(2:1)to the anlotinib and placebo groups.Kaplan–Meier analysis and log-rank test were performed to compare PFS and OS.Cox proportional hazards model was adopted for multivariate prognostic analysis.Results:Multivariate analysis indicated that high post-therapeutic peripheral blood granulocyte/lymphocyte ratio and elevated alkaline phosphatase levels were independent risk factors for PFS.Meanwhile,elevated thyroid-stimulating hormone,blood glucose,and triglyceride levels;hypertension;and hand–foot syndrome were independent protective factors of PFS.High posttherapeutic peripheral blood granulocyte/lymphocyte ratio,an Eastern Cooperative Oncology Group(ECOG)score≥2,and the sum of the maximal target lesion length at baseline were independent risk factors of OS,and hypertriglyceridemia was an independent protective factor of OS.Conclusions:This study preliminarily explored the possible factors that affected PFS and OS after anlotinib treatment in patients with advanced refractory NSCLC,and the baseline characteristics of the therapeutically dominant populations were then identified.Jing Wang Yizhuo Zhao Qiming Wang Li Zhang Jianhua Shi Zhehai Wang Ying Cheng Jianxing He Yuankai Shi Hao Yu Yang Zhao Weiqiang Chen Yi Luo Xiuwen Wang Kejun Nan Faguang Jin Jian Dong Baolan Li Zhujun Liu Baohui Han Kai Li 2018Cancer Biology & Medicine2018,15,4:46
2The 1997-1998 warm event in the South China Sea显示文摘A strong warm event happens during spring 1997 to spring 1999 in the South China Sea. Its intensity and duration show that it is the strongest event on the record over the past decades. It also corresponds with the severe flood over the valley of the Yangtze River and a couple of marine environmental events. This note addressed the evolution process by using several data sets, such as sea surface temperature, height and wind stress in addition to subsurface temperature. The onset of the warm event almost tele-connects with the El Nino event in the tropical Pacific Ocean. Summer monsoon is stronger and winter monsoon is weaker in 1997 so that there are persistent westerly anomalies in the South China Sea. During the development phase, the warm advection caused by southerly anomalies is the major factor while the adjustment of the thermocline is not obvious. Subsequently, the southerly anomalies decay and even northerly anomalies appear in the summer of 1998 resulting from the weaker than normal summerWANG Dongxiao XIE Qiang DU Yan WANG Weiqiang CHEN Ju 2002Chinese Science Bulletin2002,47,14:24
3The development and function of follicular helper T cells in immune responses显示文摘小囊的助手 T 房间(Tfh ) 作为提供帮助让 B 房间增殖并且在幼芽的中心经历抗体亲密关系成熟的一个系被提交了。证据支持了那个 Tfh 子集开发象另外的系一样,依赖于一个特别 transcriptional 节目被开始的微型环境。它为 Tfh 房间的开发和函数作为主人管理者被看了那 Bcl-6 和 IL-21 行为。Tfh dysregulation 涉及自体免疫的病理的发展,例如全身的豺狼座 erythematosus,风湿性关节炎和另外的自体免疫的疾病。现在的评论在在他们的开发和函数的 Tfh 房间和焦点的域里加亮最近的进展。Maogen Chen Zhiyong Guo Weiqiang Ju Bernhard Ryffel Xiaoshun He Song Guo Zheng 2012Cellular & Molecular Immunology2012,9,5:18
4Nonintubated uniportal video-assisted thoracoscopic surgery for primary spontaneous pneumothorax显示文摘Objective:The objective of the current study was to evaluate the feasibility and safety of nonintubated uniportal video-assisted thoracoscopic surgery(VATS) for the management of primary spontaneous pneumothorax(PSP).Methods:From November 2011 to June 2013,32 consecutive patients with PSP were treated by nonintubated uniportal thoracoscopic bullectomy using epidural anaesthesia and sedation without endotracheal intubation.An incision 2 cm in length was made at the 6^(th) intercostal space in the median axillary line.The pleural space was entered by blunt dissection for placement of a soft incision protector.Instruments were then inserted through the incision protector to perform thoracoscopic bullectomy.Data were collected within a minimum follow-up period of 10 months.Results:The average time of surgery was 49.0 min(range,33-65 min).No complications were recorded.The postoperative feeding time was 6 h.The mean postoperative chest tube drainage and hospital stay were19.3 h and 41.6 h,respectively.The postoperative pain was mild for 30 patients(93.75%) and moderate for two patients(6.25%).No recurrences of pneumothorax were observed at follow-up.Conclusions:The initial results indicated that nonintubated uniportal video-assisted thoracoscopic operations are not only technically feasible,but may also be a safe and less invasive alternative for select patients in the management of PSP.This is the first report to include the use of a nonintubated uniportal technique in VATS for such a large number of PSP cases.Further work and development of instruments are needed to define the applications and advantages of this technique.Shuben Li Fei Cui Jun Liu Xin Xu Wenlong Shao Weiqiang Yin Hanzhang Chen Jianxing He 2015Chinese Journal of Cancer Research2015,27,2:15
5TALEN-based generation of a cynomolgus monkey disease model for human microcephaly显示文摘基因在非人类的首领编辑可以为在人探索病原学和遗传上基于的神经病学的混乱的治疗学的策略导致珍贵模型。然而,仔细在人模仿病理学、行为的赤字的神经病学的混乱的一个猴子模型成功地还没被产生了。Microcephalin 1 (MCPH1 ) 在人的大脑,和智力迟钝伴随的 MCPH1 变化原因头小畸型的进化被含有。这里,我们产生了用抄写带 biallelic MCPH1 变化的一只 cynomolgus 猴子(Macaca fascicularis ) 像使活跃之物的受动器核酸酶。猴子概括了大多数在病人观察的重要临床的特征,包括在头圆周,早熟的染色体冷凝作用(PCC ) ,语料库 callosum 的发育不全和上面的手足 spasticity 的显著减小。而且,在变异的真皮的成纤维细胞的 MCPH1 的 overexpression 救了 PCC 症候群。这个猴子模型可以帮助我们阐明在人的头小畸型并且更好的致病的 MCPH1 的角色在首领大脑尺寸的进化理解这蛋白质的功能。Qiong Ke Weiqiang Li Xingqiang Lai Hong Chen Lihua Huang Zhuang Kang Kai Li Jie Ren Xiaofeng Lin Haiqing Zheng Weijun Huang Yunhan Ma Dongdong Xu Zheng Chen Xinming Song Xinyi Lin Min Zhuang Tao Wang Fengfeng Zhuang Jianzhong Xi Frank Fuxiang Mao Huimin Xia Bruce T Lahn Qi Zhou Shihua Yang Andy Peng Xiang 2016Cell Research2016,26,9:13
6Safety and feasibility of video-assisted thoracoscopic surgery for stage IIIA lung cancer显示文摘Objective: The current study was prospectively designed to explore the application of video-assisted thoracoscopic surgery(VATS) radical treatment for patients with stage IIIA lung cancer, with the primary endpoints being the safety and feasibility of this operation and the second endpoints being the survival and complications after the surgery.Methods: A total of 51 patients with radiologically or mediastinoscopically confirmed stage IIIA lung cancer underwent VATS radical treatment, during which the standard pulmonary lobectomy and mediastinal lymph node dissection were performed after pre-operative assessment. The operative time, intraoperative blood loss/complications, postoperative recovery, postoperative complications, and lymph node dissection were recorded and analyzed. This study was regarded as successful if the surgical success rate reached 90% or higher.Results: A total of 51 patients with non-small cell lung cancer(NSCLC) were enrolled in this study from March 2009 to February 2010. The median post-operative follow-up duration was 50.5 months. Of these 51 patients, 41(80.4%) had N2 lymph node metastases. All patients underwent the thoracoscopic surgeries, among whom 50(98%) received pulmonary lobectomy and mediastinal lymph node dissection completely under the thoracoscope, 6 had their incisions extended to about 6 cm due to larger tumor sizes, and 1 had his surgery performed using a 12 cm small incision for handling the adhesions between lymph nodes and blood vessels. No patient was converted to conventional open thoracotomy. No perioperative death was noted. One patient received a second surgery on the second post-operative day due to large drainage(>1,000 mL), and the postoperative recovery was satisfactory. Up to 45 patients(88.2%) did not suffer from any perioperative complication, and 6(11.8%) experienced one or more complications.Conclusions: VATS radical treatment is a safe and feasible treatment for stage IIIA lung cancer.Wenlong Shao Jun Liu Wehua Liang Hanzhang Chen Shuben Li Weiqiang Yin Xin Zhang Jianxing He 2014Chinese Journal of Cancer Research2014,26,4:12
7Porous LiFePO_(4)/NiP Composite Nanospheres as the Cathode Materials in Rechargeable Lithium Ion Batteries显示文摘We report the synthesis of porous LiFePO4/NiP composite nanospheres and their application in rechargeable lithium-ion batteries.A simple one-step spraying technique was developed to prepare LiFePO_(4)/NiP composite nanospheres with an electrical conductivity 10^(3)-10^(4) times that of bulk particles of LiFePO_(4).Electrochemical measurements show that LiFePO_(4) nanospheres with a uniform loading of 0.86 wt%1.50 wt%NiP exhibit high discharge capacity,good cycling reversibility,and low apparent activation energies.The superior electrode performance of the as-prepared composite nanospheres results from the greatly enhanced electrical conductivity and porous structure of the materials.Chunsheng Li Shaoyan Zhang Fangyi Cheng Weiqiang Ji Jun Chen 2008Nano Research2008,1,3:12
8IL-37b suppresses T cell priming by modulating dendritic cell maturation and cytokine production via dampening ERK/NF-κB/S6K signalings显示文摘Interleukin 37b (IL-37b ) 在压制有免疫力的回答起一个关键作用,部分由 modulating 树枝状的房间(DC ) 的功能。然而,精确机制大部分仍然是未知的。这里,我们在回答由 DC 导致了的 DC 成熟和 T 房间上调查了 IL-37b 的效果,并且探索了深奥发信号的小径。它被发现那 IL-37b 下面调整在 vitro 的 DC 上的 co-stimulatory 分子 CD80 和 CD86 的表情。同时,支持 inflammatory cytokines 的表情例如 TNF-6, 和 IL-6,被压制,当时 T 房间的表示禁止的 cytokine TGF- 在 IL-37b-treated DC 被增加。另外, T 房间上的 DC 的激活效果被 IL-37b 损害。我们进一步表明细胞外的调整单人赛的 kinase (英皇家空军之阶级最低之兵) ,原子 factor-B (NF-B ) ,和表明小径的 mTOR-S6K 涉及 IL-37b 导致的 DC 的抑制。这被化学禁止者的同样镇压的效果在 DC 在 IL-6 和 TNF- 的表情上对 NF-B,英皇家空军之阶级最低之兵,和 S6K 证实。在结论,这些结果证明 IL-37b 由在英皇家空军之阶级最低之兵, NF-B,和基于 S6K 的禁止的发信号小径包含在 T 房间 priming 压制了 DC 成熟和 immunostimulatory 能力。Wantong Wu Weiqiang Wang Yun Wang Wenwen Li Gang Yu Zhonglong Li Chunmin Fang Yue Shen Zhina Sun Ling Han Juan Yu Lijun Fang Song Chen Kui Dong Zhongchao Han Hanzhi Liu Yuechen Luo Xiaoming Feng 2015Acta Biochimica et Biophysica Sinica2015,47,8:8
9Long-distance ranging with high precision using a soliton microcomb显示文摘Laser-based light detection and ranging(lidar)plays a significant role in both scientific and industrial areas.However,it is difficult for existing lidars to achieve high speed,high precision,and long distance simultaneously.Here,we demonstrate a high-performance lidar based on a chip-scaled soliton microcomb(SMC)that can realize all three specialties simultaneously.Aided by the excellent properties of ultrahigh repetition rate and the smooth envelope of the SMC,traditional optical frequency comb(OFC)-based dispersive interferometry is heavily improved and the measuring dead zone induced by the mismatch between the repetition rate of the OFC and resolution of the optical spectrum analyzer is totally eliminated.Combined with an auxiliary dual-frequency phase-modulated laser range finder,the none-dead-zone measurable range ambiguity is extended up to 1500 m.The proposed SMC lidar is experimentally implemented in both indoor and outdoor environment.In the outdoor baseline field,real-time,high-speed(up to 35 k Hz)measurement of a long distance of^1179 m is achieved with a minimum Allan deviation of 5.6μm at an average time of 0.2 ms(27 nm at an average time of 1.8 s after high-pass filtering).The present SMC lidar approaches a compact,fast,high-precision,and none-dead zone long-distance ranging system,aimed at emerging applications of frontier basic scientific research and advances in industrial manufacturing.JINDONG WANG ZHIZHOU LU WEIQIANG WANG FUMIN ZHANG JIAWEI CHEN YANG WANG JIHUI ZHENG SAI T.CHU WEI ZHAO BRENT E.LITTLE XINGHUA QU WENFU ZHANG 2020Photonics Research2020,8,12:8
10Aboveground biomass and corresponding carbon sequestration ability of four major forest types in south China显示文摘We estimated aboveground biomass carbon (TABC) and net carbon accumulation rates (TNEP) for trees in four major forest types based on national forest inventory data collected in 1994-1998 and 1999-2003. The four types were Pinus massoniana forest, Cunninghamia lanceolata forest, hard broad-leaved evergreen forest and soft broad-leaved evergreen forest. We analyzed variations in TABC and TNEP for five stand ages (initiation, young, medium, mature and old). In both time periods, estimated TABC in all four forest types increased consistently with forest stand age and the oldest stage had the largest TABC compared with other stages. Broad-leaved forests (hard and soft) had higher TABC than needle-leaved forests (Pinus massoniana and Cunninghamia lanceolata) for each of the five age stages. The difference of TABC between broad-leaved and needle-leaved forests increased with forest stand age. Comparison of estimated TNEP by age category indicated TNEP increased from the initiation stage to the young stage, and then decreased from the mature stage to old stage in all four forest types. TNEP for any particular stage depended on the forest type; for instance, broad-leaved forests at both the mature and old stages had greater TNEP than in needle-leaved forests. A logistic curve was applied to fit the relationship between TABC and forest stand age. In each period, correlations in all four forest types were all statistically significant (P < 0.01) with R2 > 0.95. TABC was therefore predicted by these regression functions from 2000 to 2050 and the mean TNEP during the predicted period was estimated to be about 41.14, 31.53, 75.50 and 75.68 gCm-2a-1 in Pinus massoniana forest, Cunninghamia lanceolata forest, hard broad-leaved forest and soft broad-leaved forest, respectively. Results from both forest inventory and regression prediction suggest broad-leaved forests are greater carbon sinks, and hence have greater carbon sequestration ability especially in the mature and old stages when compared to needle-leaved forests. Broad-leaved forests should have high levels of carbon sequestration when compared with needle-leaved forests in south China.CHEN QingQing XU WeiQiang LI ShengGong FU ShengLei YAN JunHua 2013Chinese Science Bulletin2013,58,13:8
11Nonintubated thoracoscopic lobectomy plus lymph node dissection following segmentectomy for central type pulmonary masses显示文摘IntroductionLung cancer is the most common cancer worldwide.In the United States,it causes more cancer-related deaths than the next four causes(breast cancer,prostate cancer,colon cancer,and pancreatic cancer)of cancer-related mortality combined(1).About 30% of people have alreadyWenlong Shao Wei Wang Weiqiang Yin Zhihua Guo Guilin Peng Ying Chen Jianxing He 2013Chinese Journal of Cancer Research2013,25,1:7
12Developer social networks in software engineering:construction,analysis,and applications显示文摘With the increasing popularity of Internet,more and more developers are collaborating together for software development.During the collaboration,a lot of information related to software development,including communication and coordination information of developers,can be recorded in software repositories.The information can be employed to construct Developer Social Networks(DSNs)for facilitating tasks in software engineering.In this paper,we survey recent advances of DSNs and examine three fundamental steps of DSNs,namely construction,analysis,and applications.We summarize the state-of-the-art methods in the three steps and investigate the relationships among them.Furthermore,we discuss the main issues and point out the future opportunities in the study of DSNs.ZHANG WeiQiang NIE LiMing JIANG He CHEN ZhenYu LIU Jia 2014Science China(Information Sciences)2014,57,12:7
13The Chinese Hα Solar Explorer(CHASE) mission: An overview显示文摘The Chinese Hα Solar Explorer(CHASE), dubbed “Xihe”—Goddess of the Sun, was launched on October 14, 2021 as the first solar space mission of China National Space Administration(CNSA). The CHASE mission is designed to test a newly developed satellite platform and to acquire the spectroscopic observations in the Hα waveband. The Hα Imaging Spectrograph(HIS)is the scientific payload of the CHASE satellite. It consists of two observational modes: raster scanning mode and continuum imaging mode. The raster scanning mode obtains full-Sun or region-of-interest spectral images from 6559.7 to 6565.9 ? and from 6567.8 to 6570.6 ? with 0.024 ? pixel spectral resolution and 1 min temporal resolution. The continuum imaging mode obtains photospheric images in continuum around 6689 ? with the full width at half maximum of 13.4 ?. The CHASE mission will advance our understanding of the dynamics of solar activity in the photosphere and chromosphere. In this paper, we present an overview of the CHASE mission including the scientific objectives, HIS instrument overview, data calibration flow, and first results of on-orbit observations.Chuan Li Cheng Fang Zhen Li MingDe Ding PengFei Chen Ye Qiu Wei You Yuan Yuan MinJie An HongJiang Tao XianSheng Li Zhe Chen Qiang Liu Gui Mei Liang Yang Wei Zhang WeiQiang Cheng JianXin Chen ChangYa Chen Qiang Gu QingLong Huang MingXing Liu ChengShan Han HongWei Xin ChangZheng Chen YiWei Ni WenBo Wang ShiHao Rao HaiTang Li Xi Lu Wei Wang Jun Lin YiXian Jiang LingJie Meng Jian Zhao 2022Science China(Physics,Mechanics & Astronomy)2022,65,8:7
14Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity显示文摘Dear Editor,Pancreatic cancer (PCa) is a high-grade gastrointestinal malignancy more commonly occurring in elderly populations with lower than 5% overall 5-year survival rate (Hidalgo, 2010). PCa responds poorly to most chemotherapeutic agents, and therefore it is imperative to develop novel therapeutic agents that have anti-cancer activities against PCa.Juanjuan Feng Mingjin Rao Man Wang Lin Liang Zhi Chen Xiufeng Pang Weiqiang Lu Zhenliang Sun 2019Science China(Life Sciences)2019,62,10:6
15Long-term survival outcomes of video-assisted thoracic surgery for patients with non-small cell lung cancer显示文摘Background: Video-assisted thoracic surgery(VATS) has been shown to be a safe alternative to conventional thoracotomy for patients with non-small cell lung cancer(NSCLC). However, popularization of this relatively novel technique has been slow, partly due to concerns about its long-term outcomes. The present study aimed to evaluate the long-term survival outcomes of patients with NSCLC after VATS, and to determine the significant prognostic factors on overall survival.Methods: Consecutive patients diagnosed with NSCLC referred to one institution for VATS were identified from a central database. Patients were treated by either complete-VATS or assisted-VATS, as described in previous studies. A number of baseline patient characteristics, clinicopathologic data and treatment-related factors were analyzed as potential prognostic factors on overall survival.Results: Between January 2000 and December 2007, 1,139 patients with NSCLC who underwent VATS and fulfilled a set of predetermined inclusion criteria were included for analysis. The median age of the entire group was 60 years, with 791 male patients(69%). The median 5-year overall survival for Stage I, II, III and IV disease according to the recently updated TNM classification system were 72.2%, 47.5%, 29.8% and 28.6%, respectively. Female gender, TNM stage, pT status, and type of resection were found to be significant prognostic factors on multivariate analysis.Conclusions: VATS offers a viable alternative to conventional open thoracotomy for selected patients with clinically resectable NSCLC.Wenlong Shao Xinguo Xiong Hanzhang Chen Jun Liu Weiqiang Yin Shuben Li Xin Xu Xin Zhang Jianxing He 2014Chinese Journal of Cancer Research2014,26,4:5
16Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells显示文摘Nengquan Sheng Li Yan Weiqiang You Gewen Tan Jianfeng Gong Hongqi Chen Yi Yang Landian Hu Zhigang Wang 2017Acta Biochimica et Biophysica Sinica2017,49,10:4
17Multi-scale variability of the tropical Indian Ocean circulation system revealed by recent observations显示文摘The tropical Indian Ocean circulation system includes the equatorial and near-equatorial circulations, the marginal sea circulation, and eddies. The dynamic processes of these circulation systems show significant multi-scale variability associated with the Indian Monsoon and the Indian Ocean dipole. This paper summarizes the research progress over recent years on the tropical Indian Ocean circulation system based on the large-scale hydrological observations and numerical simulations by the South China Sea Institute of Oceanology(SCSIO), Chinese Academy of Sciences. Results show that:(1) the wind-driven Kelvin and Rossby waves and eastern boundary-reflected Rossby waves regulate the formation and evolution of the Equatorial Undercurrent and the Equatorial Intermediate Current;(2) the equatorial wind-driven dynamics are the main factor controlling the inter-annual variability of the thermocline in the eastern Indian Ocean upwelling;(3) the equatorial waves transport large amounts of energy into the Bay of Bengal in forms of coastal Kelvin and reflected free Rossby waves. Several unresolved issues within the tropical Indian Ocean are discussed:(i) the potential effects of the momentum balance and the basin resonance on the variability of the equatorial circulation system, and(ii) the potential contribution of wind-driven dynamics to the life cycle of the eastern Indian Ocean upwelling. This paper also briefly introduces the international Indian Ocean investigation project of the SCSIO, which will advance the study of the multi-scale variability of the tropical Indian Ocean circulation system, and provide a theoretical and data basis to support marine environmental security for the countries around the Maritime Silk Road.Ke HUANG Dongxiao WANG Weiqiang WANG Qiang XIE Ju CHEN Lingfang CHEN Gengxin CHEN 2018Science China Earth Sciences2018,61,6:4
18A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease显示文摘Chronic kidney disease(CKD)poses a great burden to global public health as current therapies are generally ineffective.Early detection and effective therapy are crucial for the future prevention and progression of CKD.Nanoparticles(NPs)vary by particle size,charge,shape and the density of targeting ligands and are associated with enhancement of the pharmacokinetic properties,targetability,or the bioavailability of drugs.Thus,the emergence of NPs in medicine has provided novel solutions to the potential diagnosis and treatment of CKD.This review describes the current experimental research,clinical applications of NPs,the current challenges,and upcoming opportunities in the diagnosis and treatment of CKD.Yanhong Ma Fanghao Cai Yangyang Li Jianghua Chen Fei Han Weiqiang Lin 2020Bioactive Materials2020,5,3:3
19Levitated-body ultra-high pointing accuracy and stability satellite platform of the CHASE mission显示文摘The CHASE satellite is designed based on the novel ultra-high pointing accuracy and stability levitated-body satellite platform,which breaks the traditional idea of rigidly connecting the satellite platform and payload. When operating in orbit, the platform and payload are non-connected and spatially levitated. By separately arranging the “noisy” and “quiet” devices, the complicated influence of platform vibration on the payload pointing direction is effectively avoided. Using the novel master-slave collaborative control method, the pointing accuracy and stability of the payload are improved considerably. In this paper, the basic principles, overall scheme, control method, and engineering implementation of a levitated-body satellite platform are discussed.Combined with the CHASE mission in-orbit data, the actual attitude pointing precision and stability of a levitated-body satellite platform are analyzed and evaluated.Wei Zhang WeiQiang Cheng Wei You Xiao Chen Jian Zhang Chuan Li Cheng Fang 2022Science China(Physics,Mechanics & Astronomy)2022,65,8:3
20True random coded photon counting Lidar显示文摘A true random coded photon counting Lidar system is proposed in this paper,in which a single photon detector acts as the true random sequence signal generator instead of the traditional function generator.Compared with the traditional pseudo-random coded method,the true random coded method not only improves the anti-crosstalk capability of the system,but more importantly,it effectively overcomes the adverse effect of the detector’s dead time on the ranging performance.The experiment results show that the ranging performance of the true random coded method is obviously better than that of the pseudo-random coded method.As a result,a three-dimensional scanning imaging of a model car is completed by the true random coded method.Bo Liu Yang Yu Zhen Chen Weiqiang Han 2020Opto-Electronic Advances2020,3,2:3
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