|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Capecitabine with radiation is an effective adjuvant therapy in gastric cancers显示文摘AIM:To analyze the outcome of patients who received concurrent capecitabine(Xeloda) and radiation(XRT) compared to the established concurrent 5-fluorouracil(5-FU) with radiation(5FU-RT) and fluoropyrimidine-based chemotherapy alone as adjuvant treatment in gastric cancers.METHODS:All patients with gastric cancers who received adjuvant treatment at the National Cancer Centre Singapore between 1996 and 2006 were reviewed.Treatment outcomes of patients who received XRT were compared with those who had 5FU-RT or chemotherapy alone as adjuvant therapy for gastric cancers.RESULTS:A total of 108 patients were reviewed.Median age at diagnosis was 60.The majority of the patients(64.8%) had advanced stage Ⅲ and Ⅳ disease(with no distant metastasis).All except 4 patients had D2 gastrectomy.Twenty one patients(19.4%) had positive surgical resection margins.Thirty three patients received XRT compared with 52 who had 5FU-RT and 23 who received chemotherapy alone.For the patients in the chemotherapy-only group,all had fluoropyrimidine-based therapy,with added cisplatin in 7 patients and epirubicin in 2 patients.Median recurrence-free survival was longer for the XRT group(52 mo) compared to the 5FU-RT(35 mo) and chemotherapy-only groups(25 mo)(P=0.48).The patients in the XRT group achieved similar median overall survival(53 mo) as the 5FU-RT(54 mo) and the chemotherapy-only groups(44 mo)(P=0.5).CONCLUSION:Capecitabine with concurrent radiation was as effective as concurrent 5FU with radiation or fluoropyrimidine-based chemotherapy alone when used as adjuvant treatment in patients with gastric cancers. | Chee Kian Tham Su Pin Choo Donald Yew Hee Poon Han Chong Toh Simon Yew Kuang Ong Sze Huey Tan Michael Lian Chek Wang Kian Fong Foo | 2010 | World Journal of Gastroenterology2010，16，29： | 6 |
| 2 | Public policy, political connections, and effective tax rates: Longitudinal evidence from Malaysia显示文摘 | Ajay Adhikari Chek Derashid Hao Zhang | 2006 | Journal of Accounting and Public Policy2006，，5： | 6 |
| 3 | Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts显示文摘TGF-β并且 myostatin 是肌肉生长的二个很重要的管理者。两个生长因素被显示了通过一条 Smad3 依赖的小径发信号。不管多么迄今为止,在肌肉生长和区别的 Smad3 的角色没被调查。这里,我们证明 Smad3 空的老鼠减少了肌肉质量和显著骨胳的肌肉萎缩。与这一致,我们也在从 Smad3 空的老鼠孤立的肌肉织物发现增加的蛋白质 ubiquitination 和 ubiquitin E3 ligase 的提高的层次 MuRF1。Smad3 的损失也导致了有缺点的卫星房间(SC ) 功能。Smad3 空的 SC 为自强显示出减少的倾向,它可以导致 SC 数字的进步损失。确实,减少了 SC 数字从显示出严重肌肉浪费的症状的 Smad3 空的老鼠在骨胳的肌肉被观察。进一步,在主要 myoblast 的 vitro 分析,文化鉴别那 Smad3 空的 myoblasts 展览损害了增长,区别和熔化,导致萎缩的 myotubes 的形成。为分子的机制的搜索表明 Smad3 的损失在 Smad3 空的肌肉和 myoblasts 导致增加的 myostatin 表示。给那 myostatin 是一个否定管理者,我们假设增加那 myostatin 层次为在 Smad3 空的老鼠的衰退显型负责。与这个理论一致,在 Smad3 空的老鼠的 myostatin 的 inactivation 救肌肉萎缩显型。 | XiaojiaGe CraigMcFarlane AnuradhaVajjala SudarsanareddyLokireddy Zhi HuiNg Chek KunTan Nguan SoonTan WalterWahli MridulaSharma RaviKambadur | 2011 | Cell Research2011，21，11： | 5 |
| 4 | Matricellular Proteins: A Sticky Affair with Cancers显示文摘 | Han Chung Chong Chek Kun Tan Royston-Luke Huang Nguan Soon Tan Dominic Fan | 2012 | Journal of Oncology2012，，： | 2 |
| 5 | Chemical myofascial necrosis: a rare com- plication of laparoscopic nephrectomy 显示文摘 | Samantha Chek Hou Kiat | 2013 | Aaz Journal of Surgery2013，83，12： | 1 |
| 6 | Metadiscourse in English and Chinese research article introductions显示文摘 | Kim Loi Chek and Lim Jason Miin-Hwa | 2013 | Discourse Studies2013，，2： | 1 |
| 7 | Theoretical analysis of the electrical and magnetic field distributions in a toroidal eore with circular cross section 显示文摘 | Darning Zhang Chek Fok Foo | 1999 | IEEE Transactions on Magnetics1999，35，3： | 1 |
| 8 | Formal specification of design pattern combination using BPSL显示文摘 | Toufik Taibi David Chek Ling Ngo | 2003 | Information and Software Technology2003，45，3： | 1 |
| 9 | Leaf rust resistance genes of wheat:identification in cultivars and resistance sources 显示文摘 | Stepie:6 L Golka L Chek]owskJ J | 2003 | J Ap- pl Genet2003，44，： | 1 |
| 10 | Detection of diverse viruses in alimentary specimens of bats in Macao显示文摘Bats carry a variety of viruses, and some of them cause public health problems. Macao, which is famous for its gambling industry, has a complex population structure. The globalization in such an international metropolis has enhanced the chance of disease transmission. Therefore, surveillance of zoonotic viruses is necessary for the early warning of potential emerging infectious diseases.Here, we report the first surveillance of bat viruses in Macao. In this study, we collected 1004 samples involving 10 bat species from 7 sites from April 2015 to May 2016, and examined the presence of viruses using nucleic acid-based methods. Coronaviruses, adenoviruses and paramyxoviruses were detected in these samples, with a high prevalence of coronaviruses. While,none was positive for hepatitis A virus, hepatitis E virus or hantavirus. Co-infections are not common in those bat species, but coronavirus HKU6 and adenovirus can be found commonly occurred in Myotis ricketti. | Jie Liang Xing-Lou Yang Bei Li Qi Liu Qin Zhang Hui Liu Hon-Pio Kan Kai-Chin Wong Si-Nga Chek Xiangyang He Xingwen Peng Zheng-Li Shi Yi Wu Libiao Zhang | 2017 | Virologica Sinica2017，32，3： | 1 |
| 11 | Scalable multiparticle entanglement of trapped ions显示文摘 | H Hfner W Hsel C F Roos J Benhelm D Chek al kar M Chwalla T Kber U D Rapol M Riebe P O Schmidt C Becher O Ghne W Dr R Blatt | 2005 | Nature2005，438，7068： | 1 |
| 12 | Stepwise advancement versus maximum jumping with headgear activator 显示文摘 | Mang Chek Wey Margareta Bendeus Li Pang | 2007 | Europ J Orthod2007，29，： | 1 |
| 13 | Public policy, political connections, and effective tax rates: Longitudinal evidence from Malaysia显示文摘 | Ajay Adhikari Chek Derashid Hao Zhang | 2006 | Journal of Accounting and Public Policy2006，，5： | 1 |
| 14 | The losses of microwave ferrites at communication frequencies显示文摘 | Chek Pin Yang P.A. Smith J. Krupka T.W. Button | 2006 | Journal of the European Ceramic Society2006，，8： | 1 |
| 15 | Puhlie Policy, Political Connections, and Effective Tax Rates: ion@m- dinal Evidence from Malaysia 显示文摘 | Ajay Adhikari Chek Derashid Hao Zhnng | 2006 | Journal of Accounting andPublic Policy2006，25，5： | 1 |
| 16 | Role of ischemia - modified albu- min in estimating the extent and scope of cardiac ischemia in pa- tients with ST elevation myocardial infarction 显示文摘 | Chek J Dusek J Stasek J | 2011 | Heart Vessels2011，26，6： | 1 |
| 17 | Swiss ball exercises for swimming,soccer and basketball显示文摘 | Chek P | 1999 | Sports Coach1999，21，4： | 1 |
| 18 | Aesthetic measures for assessing graphic screen显示文摘 | David Chek Ling Azman Samsudin Rosni Abduliah | 2000 | Journal of Information Science and Engineering2000，16，： | 1 |
| 19 | Public policy, political connections, and effective tax rates: Longitudinal evidence from Malaysia显示文摘 | Ajay Adhikari Chek Derashid Hao Zhang | 2006 | Journal of Accounting and Public Policy2006，，5： | 1 |
| 20 | Data hiding based on the similarity between neighboring pixels with reversibility显示文摘 | LI YU-CHIANG YEH CHIA-MING CHANG CHIN- CHEK | 2010 | Digital Signal Processing2010，20，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员