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| 1 | Estimation of intra-operator variability in perfusion parameter measurements using DCE-US显示文摘AIM:To investigate intra-operator variability of semiquantitative perfusion parameters using dynamic contrast-enhanced ultrasonography(DCE-US),following bolus injections of SonoVue.METHODS:The in vitro experiments were conducted using three in-house sets up based on pumping a fluid through a phantom placed in a water tank.In the in vivo experiments,B16F10 melanoma cells were xenografted to five nude mice.Both in vitro and in vivo,images were acquired following bolus injections of the ultrasound contrast agent SonoVue(Bracco,Milan,Italy) and using a Toshiba Aplio ultrasound scanner connected to a 2.9-5.8 MHz linear transducer(PZT,PLT 604AT probe)(Toshiba,Japan) allowing harmonic imaging('Vascular Recognition Imaging') involving linear raw data.A mathematical model based on the dye-dilution theory was developed by the Gustave Roussy Institute,Villejuif,France and used to evaluate seven perfusion parameters from time-intensity curves.Intra-operator variability analyses were based on determining perfusion parameter coefficients of variation(CV).RESULTS:In vitro,different volumes of SonoVue were tested with the three phantoms:intra-operator variability was found to range from 2.33% to 23.72%.In vivo,experiments were performed on tumor tissues and perfusion parameters exhibited values ranging from 1.48% to 29.97%.In addition,the area under the curve(AUC) and the area under the wash-out(AUWO) were two of the parameters of great interest since throughout in vitro and in vivo experiments their variability was lower than 15.79%.CONCLUSION:AUC and AUWO appear to be the most reliable parameters for assessing tumor perfusion using DCE-US as they exhibited the lowest CV values. | Marianne Gauthier Ingrid Leguerney Jessie Thalmensi Mohamed Chebil Sarah Parisot Pierre Peronneau Alain Roche Nathalie Lassau | 2011 | World Journal of Radiology2011，3，3： | 6 |
| 2 | Superselective embolisation of bilateral superior vesical arteries for management of intractable hematuria in context of metastatic bladder cancer显示文摘Hematuria due to locally advanced or metastatic bladder cancer is a common condition and is often a management problem.Percutaneous embolisation is a mini-invasive option to handle this situation.We report a case of a patient with a metastatic bladder cancer and who presented with an abundant hematuria and severe anemia.After failure of endoscopic resections and“flush”of radiotherapy haemostatic and refusal of cystectomy by the patient,he was treated by superselective embolisation of bilateral superior bladder arteries with excellent immediate results.The technique is safe and effective in the short term.The longterm effectiveness requires further investigation. | Ahmed Saadi Abderrazak Bouzouita Mohamed Hedi Rebai Mohamed Cherif Walid Kerkeni Haroun Ayed Amine Derouiche Hatem Rajhi Riadh Ben Slama Najla Mnif Mohamed Chebil | 2017 | Asian Journal of Urology2017，4，2： | 2 |
| 3 | Bevaeizumab injection in patients with age-related macular degeneration associated with poor initial visual acuity显示文摘 | E1 Matri L Bouraoui R Chebil A | 2012 | J Ophthalmol2012，2012，86： | 1 |
| 4 | Performance evaluation of unified medical language system (R)'s synonyms expansion to query PubMed显示文摘 | Griffon N Chebil W Rollin L | 2012 | BMC Medical Informatics and Decision Making2012，12，12： | 1 |
| 5 | Fracture of the ra- dial head :the role of excision 显示文摘 | Chebil M Kanoun ML Ben Maitigue M etal | 2007 | Tunis Med2007，39，2： | 1 |
| 6 | Enzymatic acylation offlavonoids显示文摘 | CHEBIL L HUMEAU C FALCIMAIGNE A | 2006 | Process Biochemistry2006，41，11： | 1 |
| 7 | Improvement of a rotifer ecosystem culture to promote recycling marine microalga, nannochloropsis sp.显示文摘 | Leila Chebil Shigehisa Yamasaki | 1998 | Aquacultural Engineering1998，，1： | 1 |
| 8 | Biomarker expres- sion and St Gallen molecular subtype classification in primary tumours, synchronous lymph node metastases and asynchronous relapses in primary breast cancer patients with 10 years' follow-up 显示文摘 | Falck AK Bendahl PO Chebil G | 2013 | Breast Cancer Res Treat2013，140，1： | 1 |
| 9 | Urothelial carcinoma in the pros- tatic urethra and prostate: current controversies显示文摘 | Liedberg F Chebil G Mansson W | 2007 | Expert Rev Anti- cancer Ther2007，7，3： | 1 |
| 10 | Dynamic contrast-enhanced ultrasonography (DCE-US) and anti-angiogenictreatments 显示文摘 | Lassau N Chami L Chebil M | 2011 | Discov Med2011，11，56： | 1 |
| 11 | Dynamic contrast-enhanced ultrasonography(DCE-US)and anti-angiogenic treatment显示文摘 | Lassau N Chami L Chebil M | 2011 | Discov Med2011，11，56： | 1 |
| 12 | Wavelet Decomposi- tion for the Detection and Diagnosis of Faults in Rolling Element Bearings 显示文摘 | Chebil J Noel G Mesbah M | 2009 | Jordan Journal of Mechanical and Industrial Engineering2009，3，4： | 1 |
| 13 | Solubility of flavonoids in organic solvents显示文摘 | Chebil L Humeau C Anthoni J | 2007 | Journal of Chemical and Engineering Data2007，52，： | 1 |
| 14 | Fracture of the radial head : the role of excision 显示文摘 | Chebil M Kanoun ML Ben MM | 2007 | Tunis Med2007，85，2： | 1 |
| 15 | Occurrence of ochratoxigenic fungi and ochratoxin A in grapes from a Tunisian vineyard显示文摘 | LASRAM S BELLI N CHEBIL S | 2007 | Int J Food Microbiol2007，114，3： | 1 |
| 16 | Enzymatic acylation of flavonoids 显示文摘 | Chebil L Humeau C Falcimaigne A | 2006 | Process Biochemistry2006，41，11： | 1 |
| 17 | Akt activation corre- lates with the tumor aggressiveness in Tunisian patients with bladder cancer显示文摘 | Ben Bahria-Sediki I Sampaio C Chebil M | 2015 | Tumour Biol2015，，： | 1 |
| 18 | Electrochemical detection of d-dimer as deep vein thrombosis marker using single-chain d-dimer antibody immobilized on functionalized polypyrrole显示文摘 | Chebil S Hafaiedh I Sauriat-Dorizon H | 2010 | Biosensors&Bioelectronics2010，26，2： | 1 |
| 19 | Characteristics of astigmatism in a population of Tunisian school-children显示文摘 | Ahmed Chebil Lina Jedidi Nibrass Chaker Fedra Kort Rym Limaiem Fatma Mghaieth Leila El Matri | 2015 | Middle East African Journal of Ophthalmology2015，，3： | 1 |
| 20 | assessing the efficiency of irrigation water users ' associations and its determinants: evidence from Tunisia显示文摘 | Frija A Speelman S Chebil A | 2009 | Irrigation and Drainage2009，，58： | 1 |
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