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| 1 | Role of receptor tyrosine kinases in gastric cancer: New targets for a selective therapy显示文摘受体酷氨酸家族 ases (RTK ) 象表皮的生长因素受体家庭那样包括增长和变形传播参予肿瘤形成的几步。几已知的 RTK 起来在是主要的胃的癌症调整了定制的治疗的目标。仅仅初步的数据然而,在使用上存在当前临床上可得到的药象在胃的癌症的背景的 trastuzumab, cetuximab, bevacizumab, gefitinib, erlotinib,和 imatinib 那样。现出症状之前的潜的数据建议他们的使用的一个潜在的好处,特别在有“常规”的抑制细胞的联合治疗。这评论象新途径和药一样在癌症治疗关于他们的使用总结当前的知识优化治疗成功。 | JC Becker C Müller-Tidow H Serve W Domschke T Pohle | 2006 | World Journal of Gastroenterology2006，12，21： | 19 |
| 2 | 家庭锻炼对跌倒后的高危社区老年人后续跌倒的影响:一项随机临床试验显示文摘锻炼是否减少已经历跌倒的高风险老年人后续发生跌倒的风险尚不清楚。为评估家庭锻炼计划被转诊到跌倒预防诊所的老年人再发生跌倒风险的效果,本研究在2009年4月22日至2018年6月5日期间,在过去12个月内发生过跌倒的70岁以上的人群中招募研究对象进行为期12个月的单盲随机临床试验,参与者被随机分配到干预组和常规护理组,干预组(n=173)接受常规护理和物理治疗师提供的家庭力量和平衡再训练计划,常规护理组(n=172)接受老年病医生提供的防跌护理。 | Liu-Ambrose T Davis JC Best JR 袁淑娟(编译) 胡国清(编译) | 2019 | 中华预防医学杂志2019，53，9： | 8 |
| 3 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 4 | Mechanism of frost heave by film water migration under temperature gradient显示文摘IT is well known that there exists unfrozen film water in frozen soils due to the action of sur-face energy among soil particles and frost heave occurs by water migration under the tempera-ture gradient. The problem is how to determine the amount of frost heave quantitatively. The amount of frost heave induced by ice segregation can be calculated by the following e-quations: | Xu, XZ Wang, JC Zhang, LX Deng, YS Chuvilin, EM Yershov, ED Ishizaki, T Fukuda, M | 1997 | Chinese Science Bulletin1997，42，15： | 6 |
| 5 | Multiple lymphomatous polyposis of the gastrointestinal tract: Prospective clinicopathologic study of 31 cases显示文摘 | A Ruskone-Fourmestraux A Delmer A Lavergne T Molina N Brousse J Audouin JC Rambaud | 1997 | Gastroenterology1997，，1： | 2 |
| 6 | Hepatic stem-like cells in hepatoblastoma: expression of cytokeratin 7, albumin and oval cell associated antigens detected by OV-1 and Ov-6显示文摘 | Xiao JC Pietsch T | 1997 | Histopathology1997，31，： | 1 |
| 7 | The effect of interleukin-6 on polymorphonuclear leukocytes in the circulation and bone显示文摘 | English D Hogg JC | 2000 | Am J Respir Crit Care Med2000，161，： | 1 |
| 8 | Cell cycle progression and apoptosis after irradiation in an acidic environment cell death 显示文摘 | Park H J Lyons JC Ohtsubo T | 2000 | Differ2000，7，： | 1 |
| 9 | Factors predictive of liver cirrhosis in patients with chronic hepatitis B:a multivariate analysis in a longitudinal study显示文摘 | Huo T Wu JC Hwang SJ | 2000 | Eur J Gastroenterol Hepatol2000，12，6： | 1 |
| 10 | High levels of serum fibroblast growth factor(FGF)-23 are associated with increased mortality in long haemodialysis patients显示文摘 | Jean G Terrat JC Vanel T | 2009 | Nephrol Dial Transplant2009，24，： | 1 |
| 11 | Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in ahuman leukemia cell line显示文摘 | Miyashita T Reed JC | 1993 | Blood1993，81，： | 1 |
| 12 | Tumor suppressor p53 is a direct transcriptional activator of the human bax gene显示文摘 | Miyashita T Reed JC | 1995 | Cell1995，80，12： | 1 |
| 13 | Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines 显示文摘 | Flohr T Dai JC Buttner J | 1999 | Int J Cancer1999，80，6： | 1 |
| 14 | Effects of mechanical insufflation-exsufflation in preventing respiratory failure after extubation:a randomized controlled trial显示文摘 | Gonalves MR Honrado T Winck JC | 2012 | Crit Care2012，16，2： | 1 |
| 15 | The effect of presentation and mode of delivery on neonatal outcome in the second twin显示文摘 | Greig PC Veille JC Morgan T | 1992 | Am J Obstet Gynecol1992，167，4： | 1 |
| 16 | Microvascular changes in the diabetic foot显示文摘 | Schramm JC Dinh T Veves A | 2006 | Int J Low Extrem Wounds2006，5，3： | 1 |
| 17 | Photodynamic therapy for palliation of nonresectable bile duct cancer-preliminary results with a new diode laser system显示文摘 | Zoepf T Jakobs R Arnold JC | 2001 | Am J Gastroenterol2001，96，： | 1 |
| 18 | World Health Organization Pulmonary Hypertension Group2:pulmonary hypertension due to left heart disease in the adult-a summary statement from the Pulmonary Hypertension Council of the International Society for Heart and Lung Transplantation显示文摘 | Fang JC DeMarco T Givertz MM | | 0，，09： | 1 |
| 19 | Thrombin-activatable fibrinolysis inhibitor (TAFI) deficient mice are susceptible to intracerebral thrombosis and ischemic stroke 显示文摘 | Kraft P Schwarz T Meijers JC | 2010 | PLoS One2010，5，11： | 1 |
| 20 | Mycoplasmapneumoniae-associated encephalitis in childhood--nervoussystem disorder during or after a respiratory tract infection显示文摘 | Meyer Sauteur PM Streuli JC Iff T | 2011 | Klin Padiatr2011，223，4： | 1 |
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