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| 1 | Review on the Tectonic Terranes Associated with Metallogenic Zones in Southeast Asia显示文摘The paper presents an overview of the relationships between the interior structures of tectonic terranes and the distribution of tectonic-metallogenic zones in Southeast Asia. Episodic tectonic activities occurred in this archipelagic area, generating metallogenic belts in multi-terranes. Since the Late Paleozoic, opening and closure of the Paleotethys and Neotethys led to multiple suture zones between different blocks, mainly between the Indochina terrane, the Nambung terrane, the Sibumasu terrane and the West Myanmar terrane. During the Mesozoic to Cenozoic, the formation of accreted terranes and their related islands was caused by subduction and collision processes between the Pacific and Australian plates toward the Eurasian Continent, forming Sundaland and its affiliated islands, the Philippines and its subsidiary islands, the Papua New Guinea terrane and its related islands and the Sunda epicontinental arc system. Within the margin of terranes resulted in the structural transfer zones, their secondary tectonic units can be divided into island arc belts, back-arc basins, suture zones, marginal fold belts and orogenic belts. The metallogenic assemblages are mainly distributed within these structural zones of the terranes. According to the relationship between these tectonic units and the distribution of mineral resources, the tectonic-metallogenic belts can be divided into 24 metallogenic belts in Southeast Asia. They are characterized by a diversity and frequency of metallogenic material combination which is likely to reflect the complexity of the material distribution during mineralization processes, mostly by the structural transformation during the dissociation-convergence process between multiple terranes. Therefore, the formation of ore deposits was not only restricted by the evolution(opening and closure) of Paleo-and Neotethys, but may also be controlled by the interaction of the terranes with different tectonic attributes which provided multiple sources of metallogenic material. | Zhengwei Zhang Qiao Shu Xiaoyong Yang Chengquan Wu Chaofei Zheng Jinhong Xu | 2019 | Journal of Earth Science2019，30，1： | 1 |
| 2 | Mechanoresponsive MiR-138-5p Targets MACF1 to Inhibit Bone Formation显示文摘Mechanical stimuli play an essential role in maintaining bone remodeling and skeletal integrity.Meanwhile,bone can respond to the changes of mechanical condition to adjust its mass and architecture.Clinical studies discover that bedridden patients showed osteoporotic T-scores and low bone mineral density,and long-term immobilized patients presented reduced markers of bone formation.However,as bone formation mediated by osteoblast differentiation is a complex process,the underlying molecular mechanism of mechanical stimuli regulating bone formation is still unclear.Recent evidences show that microRNAs(miRNAs)are involved in mechanical stimuli regulating bone formation or osteoblast differentiation.Nevertheless,no direct evidence identifies mechanoresponsive miRNA in both human and animal bones,and clarifies its mechanoresponsive role under different mechanical conditions(e.g.mechanical unloading,reloading,loading).In the current study,we screened for differentially expressed miRNAs in bone specimens of bedridden patients with fractures,then identified that the expression of miR-138-5p,but not the other miRNAs,altered withbedridden time and was negatively correlated with the expression of the bone formation marker genes Alp(alkaline phosphatase).Moreover,miR-138-5p was up-regulated with reduced bone formation during unloading and down-regulated with increased bone formation during reloading in hind4imb unloaded mice.In addition,miR-138-5p was verified to be responsive to different mechanical unloading condition and cyclic mechanical stretch condition in primary osteogenic cells,respectively.Further in vitro data suggested that mechanoresponsive miR-138-5p directly targeted microtubule actin crosslinking factor 1(MACF1)to inhibit osteoblast differentiation.In vivo,we constructed an osteoblastic miR-138-5p transgenic mice model(TG138)with the Runx2promoter,and found that overexpression miR-138-5p supressed bone formation.Moreover,osteoblast-targeted inhibition of miR-138-5p sensitized bone anabolic response to mechanical loading in TG138 mice.Predominantly,the osteoblast-targeted inhibition of miR-138-5p could counteract bone formation reduction induced by hind limb unloading.Taken together,the mechanoresponsive miR-138-5p inhibited bone anabolic response for developing a novel bone anabolic sensitization strategy. | Zhihao Chen Zhao Fan Liang Chao Lifang Hu Chen Lei Zhang Yan Yin Chong Dijie Li Tian Ye Wuxia Qiu Kewen Zhang Chaofei Yang Xiaona Li Li Yu Weiyi Chen Zhang Ge Qian Airong | 2019 | 医用生物力学2019，34，A01： | 1 |
| 3 | The trinity pattern of Au deposits with porphyry, quartz–sulfide vein and structurally-controlled alteration rocks in Ciemas, West Java, Indonesia显示文摘 | Zhengwei Zhang Chengquan Wu Xiaoyong Yang Chaofei Zheng Junhua Yao | 2015 | Ore Geology Reviews2015，，： | 1 |
| 4 | Validation and accuracy analysis of wind products from scatterometer onboard the HY-2B satellite显示文摘The Chinese marine dynamic environment satellite HY-2B was launched in October 2018 and carries a Ku-band scatterometer.This paper focuses on the accuracies of HY-2B scatterometer wind data during the period from November 2018 to May 2021.The HY-2B wind data are validated against global moored buoys operated by the U.S.National Data Buoy Center and Tropical Atmosphere Ocean,numerical model data by the National Centers for Environmental Prediction,and the Advanced Scatterometer data issued by the Remote Sensing System.The results showed that the wind speeds and directions observed by the HY-2B scatterometer agree well with these buoy wind measurements.The root-mean-squared errors(RMSEs)of the HY-2B wind speed and direction are 0.74 m/s and 11.74°,respectively.For low wind speeds(less than 5 m/s),the standard deviation of the HY-2B-derived wind direction is higher than 20°,which implies that the HY-2B wind direction for low wind speeds is less accurate than that for moderate to high wind speed ranges.The RMSE of the HY-2B wind speed is slightly larger in high latitude oceans(60°–90°S and 60°–90°N)than in low latitude regions.Furthermore,the dependence of the residuals on the cross-track location of wind vector cells and the stability of the HY-2B scatterometer wind products are discussed.The wind stability assessment results indicate that a clear yearly oscillation is observed for the HY-2B wind speed bias which is due to seasonal weather variations.In general,the accuracy of HY-2B winds meets the operational precision requirement and is consistent with other wind data. | Sheng Yang Bo Mu Haoqiang Shi Chaofei Ma Wu Zhou Juhong Zou Mingsen Lin | 2023 | Acta Oceanologica Sinica2023，42，2： | 0 |
| 5 | Microtubule actin crosslinking factor 1 functions as a novel therapeutic target in lung metastasis of osteosarcoma显示文摘Lung metastasis is the primary cause of death in osteosarcoma(OS)patients.1 A better understanding of the molecular mechanisms underlying OS tumorigenesis and metastasis is urgently needed to identify therapeutic targets.Microtubule actin crosslinking factor 1(MACF1),which belongs to the spectraplakin family of cytoskeletal crosslinking proteins,2 is critical for cell migration and polarization due to its regulation of the cytoskeleton.Recently,MACF1 was indicated to be involved in the metastatic invasion of some human cancers,3 but the function of MACF1 in OS is still unclear. | Chaofei Yang Ye Tian Fan Zhao Qian Huang Zhiyong Liu Chenyang He Hui Li Yu li Zhiping Miao Airong Qian | 2023 | Genes & Diseases2023，10，2： | 0 |
| 6 | LAND DEGRADATION AND ITS CONTROL STRATEGIES IN CHINA显示文摘Human induced land degradation refers to decline or loss of biological or economic productivity resulting from a process or combination of processes, including displacement of soil matreial, terrain deformation and loss of nutrients and/or orgnic matter through wind erosion, water erosion, secondary salinization and pollution. Wind erosion is a major problem in the dry land of China and the area of sandy desertified land caused by wind erosion has reached 371,000 km 2. Water erosion frequently occurs in hilly and mountainous areas where 1.79 million km 2 of land have been observed and degraded land area affected by secondary salinization now covers 63,000 km 2 in China. Statistical data indicated that depletion of soil nutriution is a serious problem in China. Some 460,000 km 2 of cultivated or 46 percent of the total cultivated land area is deficient in P, and 330,000 km 2 of cultivated land or one-third of nation′s total is deficient in K. Adverse human activities are recognized as a principal reason of land degradation. In northern China, 30.1 percent of land degradation caused by over grazing, 26.9 percent by over reclamation, 33.7 percent by excessive fuel collection, 9.6 percent by mis-use of water resources, as well as 0.7 percent by industrial, mining and transportation construction. In southern China, 37 percent of degraded land caused by deforestation, 35 percent by slopeland reclamation, 18 percent by improper afforestation, and 10 percent by industrial, mining and transportation construction. Following the discussion of the causes and disasters of land degradation, this paper presents the achievements gained in prevention and control of land degradation since 1949. The several control strategic measures in combating land degradation such as prompting public awareness and people’s participation, strengthening national laws and policies formulation, carrying out projects on rehabilization and monitoring, are proposed by the end of this paper. | Yang Chaofei Dapartment of Natural Conservation, National Environmental Protection Agency, Beijing 100035 People’s Republic of China | 1997 | Journal of Geographical Sciences1997，7，2： | 0 |
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