|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Early Paleozoic ridge subduction in the Chinese Altai: Insight from the abrupt change in zircon Hf isotopic compositions显示文摘Zircons were separated from granitoids, gneisses, and sedimentary rocks of the Chinese Altai. Those with igneous characteristics yielded U-Pb ages of 280-2800 Ma, recording a long history of magmatic activity in the region. Zircon Hf isotopic compositions show an abrupt change at ~420 Ma, indicating that prior to that time the magmas came from both ancient and juvenile sources, whereas younger magmas were derived mainly from juvenile material. This may imply that the lithosphere was signifi- cantly modified in composition by a rapid addition of melt from the mantle. We suggest that this dramatic change was due to the onset of ridge subduction, which can account not only for the formation of voluminous granitoids, mafic rocks with complex compositions, and the association of adakite + high-Mg andesite + boninite + Nb-enriched basalt, but also for the coeval high-T, low-P metamorphism. | SUN Min LONG XiaoPing CAI KeDa JIANG YingDe WANG BuYun YUAN Chao ZHAO GuoChun XIAO WenJiao WU FuYuan | 2009 | Science China Earth Sciences2009，52，9： | 33 |
| 2 | The prognostic value of preoperative serum levels of CEA,CA19-9 and CA72-4 in patients with colorectal cancer显示文摘INTRODUCTIONCarcinoembryonic antigen ( CEA) , originally described by Gold and Freedman [1] in 1965, is now an acknowledged member of immunoglobulin superfamily[2],with a role as an intracellular adhesion molecule[3].Carbohydrate antigen 19-9(CA19-9), obtained with a monoclonal antibody produced by immunizing a monoclonal antibody produced by immunizing a mouse with a colonic cancer cell line in 1979[4],is a ligand for E-selectin that plays an important role in the addhesion of cancer cells to endothelial cells [5,6]. | Chao Xu Zheng~1 Wen Hua Zhan~1 Ji Zong Zhao~2 Dong Zheng~3 Dong Ping Wang~1 Yu Long He~1 Zhang Qing Zheng~1 ~1Department of General Surgery,~2Laboratory of Surgery,~3Department of Medicine,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,Guangzhou 510080,Guangdong Province,ChinaDr.Chao Xu Zheng now working as a surgeon and lecturer in the Department of General Surgery,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,who is a Ph.D.student,having 7 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 25 |
| 3 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis显示文摘 | Huang Norden E. Shen Zheng Long Steven R. Wu Manli C. Shih Hsing H. Zheng Quanan Yen Nai-Chyuan Tung Chi Chao Liu Henry H | 1998 | Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences . 1998 (1971)1998，，1971： | 22 |
| 4 | Overexpression of P53 and its risk factors in esophageal cancer in urban areas of Xi′an显示文摘OverexpressionofP53anditsriskfactorsinesophagealcancerinurbanareasofXi′anQIAOGuiBin1,HANChengLong2,JIANGRenChao1,SUNChang?.. | QIAO GuiBin1, HAN ChengLong2, JIANG RenChao1, SUN ChangSheng3, WANG Yan3 and WANG YunJie3 | 1998 | World Journal of Gastroenterology1998，4，1： | 21 |
| 5 | Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response显示文摘Background:Patient-derived organoids and xenografts(PDXs)have emerged as powerful models in functional diag-nostics with high predictive power for anticancer drug response.However,limitations such as engraftment failure and time-consuming for establishing and expanding PDX models followed by testing drug efficacy,and inability to subject to systemic drug administration for ex vivo organoid culture hinder realistic and fast decision-making in selecting the right therapeutics in the clinic.The present study aimed to develop an advanced PDX model,namely MiniPDX,for rapidly testing drug efficacy to strengthen its value in personalized cancer treatment.Methods:We developed a rapid in vivo drug sensitivity assay,OncoVee®MiniPDX,for screening clinically relevant regimens for cancer.In this model,patient-derived tumor cells were arrayed within hollow fiber capsules,implanted subcutaneously into mice and cultured for 7 days.The cellular activity morphology and pharmacokinetics were systematically evaluated.MiniPDX performance(sensitivity,specificity,positive and negative predictive values)was examined using PDX as the reference.Drug responses were examined by tumor cell growth inhibition rate and tumor growth inhibition rate in PDX models and MiniPDX assays respectively.The results from MiniPDX were also used to evaluate its predictive power for clinical outcomes.Results:Morphological and histopathological features of tumor cells within the MiniPDX capsules matched those both in PDX models and in original tumors.Drug responses in the PDX tumor graft assays correlated well with those in the corresponding MiniPDX assays using 26 PDX models generated from patients,including 14 gastric cancer,10 lung cancer and 2 pancreatic cancer.The positive predictive value of MiniPDX was 92%,and the negative predictive value was 81%with a sensitivity of 80%and a specificity of 93%.Through expanding to clinical tumor samples,Min-iPDX assay showed potential of wide clinical application.Conclusions:Fast in vivo MiniPDX assay based on capsule implantation was developed-to assess drug responses of both PDX tumor grafts and clinical cancer specimens.The high correlation between drug responses of paired MiniPDX and PDX tumor graft assay,as well as translational data suggest that MiniPDX assay is an advanced tool for personalized cancer treatment. | Feifei Zhang Wenjie Wang Yuan Long Hui Liu Jijun Cheng Lin Guo Rongyu Li Chao Meng Shan Yu Qingchuan Zhao Shun Lu Lili Wang Haitao Wang Danyi Wen | 2018 | Cancer Communications2018，38，1： | 20 |
| 6 | Quantum secure direct dialogue using Einstein-Podolsky-Rosen pairs显示文摘A two-step quantum secure direct dialogue protocol using Einstein-Podolsky-Rosen(EPR)pair block is proposed.In the protocol,the dialogue messages are encoded on series of qubits and sent through a quantum channel directly.The security of the protocol is assured by its connection to the two-step quantum secure direct communication protocol,which has been proved secure.This protocol has several advantages.It is a direct communication protocol that does not require a separate classical communication for the ciphertext.It has high capacity as two bits of secret messages can be transmitted by an EPR pair.As a dialogue protocol,the two parties can speak to each other either simultaneously or sequentially. | ZHENG Chao LONG GuoFei | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，7： | 18 |
| 7 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis显示文摘 | Huang Norden E. Shen Zheng Long Steven R. Wu Manli C. Shih Hsing H. Zheng Quanan Yen Nai-Chyuan Tung Chi Chao Liu Henry H | 1998 | 1998 (1971)1998，，1971： | 18 |
| 8 | The discovery of the oldest rocks in the Kuluketage area and its geological implications显示文摘The basement rocks in the Kuluketage area are composed predominately of tonalite-trondhjemite-granodiorite rocks, and occured mainly in Xinger and Korla. U-Pb dating of TTG gneiss near Korla yielded a late Neoarchean weighted mean 207Pb/206Pb age of 2.65 Ga, which is the oldest published age for the TTG rocks in the Kuluketage area and thus suggests that Archean terrane in the area was formed in the late Neoarchean. The Korla gneiss is much younger than the TTG rocks in the northern Altyn Tagh, eastern Tarim Craton, indicating that the oldest terrane of the Tarim Craton was exposed probably in the northern Altyn Tagh. Until late Neoarchean, the Tarim continent extends to the Kuluketage area and finally had generated a relatively large uniform Archean basement within the craton. Zircon Hf isotopic analyses of the TTG gneiss give low εHf(t) values (-5 to 1) with Paleoarchean to Mesoarchean two-stage model ages (TDM2) between 3.0 and 3.3 Ga, suggesting that the basement rocks in the northern Tarim Craton were derived dominately from partial melting of Paleoarchean to Mesoarchean juvenile crustal material. The Hf model ages, therefore, indicate that no continent crust older than 3.3 Ga existed in the Kuluketage area. | LONG XiaoPing YUAN Chao SUN Min XIAO WenJiao ZHAO GuoChun ZHOU KeFa WANG YuJing HU AiQin | 2011 | Science China Earth Sciences2011，54，3： | 16 |
| 9 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis显示文摘 | Huang Norden E. Shen Zheng Long Steven R. Wu Manli C. Shih Hsing H. Zheng Quanan Yen Nai-Chyuan Tung Chi Chao Liu Henry H | 1998 | Proceedings of the Royal Society A: Mathematical Physical and Engineering Sciences1998，，1971： | 15 |
| 10 | Response-surface-based structural reliability analysis with random and interval mixed uncertainties显示文摘Traditional reliability analysis requires probability distributions of all the uncertain parameters.However,in many practical applications,the variation bounds can be only determined for the parameters with limited information.A complex hybrid reliability problem then will be caused when the random and interval variables coexist in a same structure.In this paper,by introducing the response surface technique,we develop a new hybrid reliability method to efficiently compute the interval of the failure probability of the structure due to the probability-interval hybrid uncertainty.The present method consists of a sequence of iterations.At each step,a response surface model is constructed for the limit-state function by using a quadratic polynomial and a modified axial experimental design method.An approximate hybrid reliability problem is created based on the response surface model,which is subsequently solved by an efficient decoupling approach.An updating strategy is suggested to improve the quality of the response surface and whereby ensure the reliability analysis precision.A computational procedure is then summarized for the whole iterations.Four numerical examples and also a practical application are provided to demonstrate the effectiveness of the present method. | HAN Xu JIANG Chao LIU LiXin LIU Jie LONG XiangYun | 2014 | Science China(Technological Sciences)2014，57，7： | 14 |
| 11 | High-capacity porous carbons prepared by KOH activation of activated carbon for supercapacitors显示文摘High-performance supercapacitor electrode materials are prepared from the commercially available activated carbon(AC) through a facile and low-cost chemical activation method.The obtained results show that AC activated by KOH with an alkali/carbon ratio of 6/1(ACK6) possesses a specific surface area of 3405 m^2/g,a large pore volume of 2.01 cm^3/g,and exhibits the highest initial specific capacitance of335 F/g at the current density of 0.5 A/g in 6 mol/L KOH,and 85%coloumbic efficiency for 5000 cycles at20 mV/s. | Yong Xiao Chao Long Ming-Tao Zheng Han-Wu Dong Bing-Fu Lei Hao-Ran Zhang Ying-Liang Liu | 2014 | Chinese Chemical Letters2014，25，6： | 13 |
| 12 | Facile synthesis of Fe/Ni bimetallic oxide solid-solution nanoparticles with superior electrocatalytic activity for oxygen evolution reaction显示文摘懒惰的氧进化反应(OER ) 是电气化学的切开水的反应的重要一半反应。非结晶的 Fe/Ni 合成氧化物举办高活动。在这个工作,我们修改了喷雾器帮助水花的途径和获得的非结晶的 Fe-Ni-O x 稳固答案的 nanoparticles (Fe-Ni-O x -NPs) 在由作为原料选铁 / 镍为 acetylacetonates 而不是无机的盐的尺寸的约 20 nm。小型的 Fe-Ni-O x -NPs 被扫描电子描绘显微镜学(SEM ) ,传播电子显微镜学(TEM ) , X 光检查衍射(XRD ) 分析,精力散的 X 光检查光谱学(EDX ) ,和 X 光检查光电子光谱学(XPS ) 。而且,电气化学的 OER 性能的调查建议小型的 Fe-Ni-O x -NPs 比大尺寸的 Fe-Ni-O x -MPs 举办更高的活动。0.315 V 的小过电位被要求获得 50 妈 / 厘米 2, 的工作当前的密度, Tafel 斜坡象 38 mV/dec 一样低。 | Lingxiao Wang Jing Geng Wenhai Wang Chao Yuan Long Kuai Baoyou Geng | 2015 | Nano Research2015，8，12： | 12 |
| 13 | Carbon pools and fluxes in the China Seas and adjacent oceans显示文摘The China Seas include the South China Sea, East China Sea, Yellow Sea, and Bohai Sea. Located off the Northwestern Pacific margin, covering 4700000 km^2 from tropical to northern temperate zones, and including a variety of continental margins/basins and depths, the China Seas provide typical cases for carbon budget studies. The South China Sea being a deep basin and part of the Western Pacific Warm Pool is characterized by oceanic features; the East China Sea with a wide continental shelf, enormous terrestrial discharges and open margins to the West Pacific, is featured by strong cross-shelf materials transport; the Yellow Sea is featured by the confluence of cold and warm waters; and the Bohai Sea is a shallow semiclosed gulf with strong impacts of human activities. Three large rivers, the Yangtze River, Yellow River, and Pearl River, flow into the East China Sea, the Bohai Sea, and the South China Sea, respectively. The Kuroshio Current at the outer margin of the Chinese continental shelf is one of the two major western boundary currents of the world oceans and its strength and position directly affect the regional climate of China. These characteristics make the China Seas a typical case of marginal seas to study carbon storage and fluxes. This paper systematically analyzes the literature data on the carbon pools and fluxes of the Bohai Sea,Yellow Sea, East China Sea, and South China Sea, including different interfaces(land-sea, sea-air, sediment-water, and marginal sea-open ocean) and different ecosystems(mangroves, wetland, seagrass beds, macroalgae mariculture, coral reefs, euphotic zones, and water column). Among the four seas, the Bohai Sea and South China Sea are acting as CO_2 sources, releasing about0.22 and 13.86–33.60 Tg C yr^(-1) into the atmosphere, respectively, whereas the Yellow Sea and East China Sea are acting as carbon sinks, absorbing about 1.15 and 6.92–23.30 Tg C yr^(-1) of atmospheric CO_2, respectively. Overall, if only the CO_2 exchange at the sea-air interface is considered, the Chinese marginal seas appear to be a source of atmospheric CO_2, with a net release of 6.01–9.33 Tg C yr^(-1), mainly from the inputs of rivers and adjacent oceans. The riverine dissolved inorganic carbon (DIC) input into the Bohai Sea and Yellow Sea, East China Sea, and South China Sea are 5.04, 14.60, and 40.14 Tg C yr^(-1),respectively. The DIC input from adjacent oceans is as high as 144.81 Tg C yr^(-1), significantly exceeding the carbon released from the seas to the atmosphere. In terms of output, the depositional fluxes of organic carbon in the Bohai Sea, Yellow Sea, East China Sea, and South China Sea are 2.00, 3.60, 7.40, and 5.92 Tg C yr^(-1), respectively. The fluxes of organic carbon from the East China Sea and South China Sea to the adjacent oceans are 15.25–36.70 and 43.93 Tg C yr^(-1), respectively. The annual carbon storage of mangroves, wetlands, and seagrass in Chinese coastal waters is 0.36–1.75 Tg C yr^(-1), with a dissolved organic carbon(DOC) output from seagrass beds of up to 0.59 Tg C yr^(-1). Removable organic carbon flux by Chinese macroalgae mariculture account for 0.68 Tg C yr^(-1) and the associated POC depositional and DOC releasing fluxes are 0.14 and 0.82 Tg C yr^(-1), respectively. Thus, in total, the annual output of organic carbon, which is mainly DOC, in the China Seas is 81.72–104.56 Tg C yr^(-1). The DOC efflux from the East China Sea to the adjacent oceans is 15.00–35.00 Tg C yr^(-1). The DOC efflux from the South China Sea is 31.39 Tg C yr^(-1). Although the marginal China Seas seem to be a source of atmospheric CO_2 based on the CO_2 flux at the sea-air interface, the combined effects of the riverine input in the area, oceanic input, depositional export,and microbial carbon pump(DOC conversion and output) indicate that the China Seas represent an important carbon storage area. | Nianzhi JIAO Yantao LIANG Yongyu ZHANG Jihua LIU Yao ZHANG Rui ZHANG Meixun ZHAO Minhan DAI Weidong ZHAI Kunshan GAO Jinming SONG Dongliang YUAN Chao LI Guanghui LIN Xiaoping HUANG Hongqiang YAN Limin HU Zenghu ZHANG Long WANG Chunjie CAO Yawei LUO Tingwei LUO Nannan WANG Hongyue DANG Dongxiao WANG Si ZHANG | 2018 | Science China Earth Sciences2018，61，11： | 12 |
| 14 | State-of-the-Art Analysis and Perspectives for Peer-to-Peer Energy Trading显示文摘As a promising solution to address the“energy trilemma”confronting human society,peer-to-peer(P2P)energy trading has emerged and rapidly developed in recent years.When carrying out P2P energy trading,customers with distributed energy resources(DERs)are able to directly trade and share energy with each other.This paper summarizes and analyzes the global development of P2P energy trading based on a comprehensive review of related academic papers,research projects,and industrial practice.Key aspects in P2P energy trading are identified and discussed,including market design,trading platforms,physical infrastructure and information and communication technology(ICT)infrastructure,social science perspectives,and policy.For each key aspect,existing research and practice are critically reviewed and insights for future development are presented.Comprehensive concluding remarks are provided at the end,summarizing the major findings and perspectives of this paper.P2P energy trading is a growing field with great potential and opportunities for both academia and industry across the world. | Yue Zhou Jianzhong Wu Chao Long Wenlong Ming | 2020 | Engineering2020，6，7： | 12 |
| 15 | Heterostructured Electrocatalysts for Hydrogen Evolution Reaction Under Alkaline Conditions显示文摘The hydrogen evolution reaction(HER) is a half-cell reaction in water electrolysis for producing hydrogen gas. In industrial water electrolysis, the HER is often conducted in alkaline media to achieve higher stability of the electrode materials. However, the kinetics of the HER in alkaline medium is slow relative to that in acid because of the low concentration of protons in the former.Under the latter conditions, the entire HER process will require additional effort to obtain protons by water dissociation near or on the catalyst surface. Heterostructured catalysts, with fascinating synergistic effects derived from their heterogeneous interfaces, can provide multiple functional sites for the overall reaction process. At present, the activity of the most active known heterostructured catalysts surpasses(platinum-based heterostructures) or approaches (noble-metal-free heterostructures) that of the commercial Pt/C catalyst under alkaline conditions, demonstrating an infusive potential to break through the bottlenecks. This review summarizes the most representative and recent heterostructured HER catalysts for alkaline medium. The basics and principles of the HER under alkaline conditions are first introduced, followed by a discussion of the latest advances in heterostructured catalysts with/without noblemetal-based heterostructures. Special focus is placed on approaches for enhancing the reaction rate by accelerating the Volmer step. This review aims to provide an overview of the current developments in alkaline HER catalysts, as well as the design principles for the future development of heterostructured nano-or micro-sized electrocatalysts. | Jumeng Wei Min Zhou Anchun Long Yanming Xue Hanbin Liao Chao Wei Zhichuan J.Xu | 2018 | Nano-Micro Letters2018，10，4： | 11 |
| 16 | The Coix Genome Provides Insights into Panicoideae Evolution and Papery Hull Domestication显示文摘Coix is a grass crop domesticated as early as the Neolithic era.It is still widely cultivated for both highly nutritional food and medicinal use.However,the genetic study and breeding of this crop are hindered by the lack of a sequenced genome.Here,we report de novo sequencing and assembly of the 1619-Mb genome of Coix,and annotation of 75.39%repeats and 39629 protein-coding genes.Comparative genomics analysis showed that Coix is more closely related to sorghum than maize,but intriguingly only Coix and maize had a recent genome duplication event,which was not detected in sorghum.We further constructed a genetic map and mapped several important traits,especially the strength of hull.Selection of papery hull(thin:easy dehulling)from the stony hull(thick:difficult dehulling)in wild progenitors was a key step in Coix domestication.The papery hull makes seed easier to process and germinate.Anatomic and global transcriptome analysis revealed that the papery hull is a result of inhibition of cell division and wall biogenesis.We also successfully demonstrated that seed hull pressure resistance is controlled by two major quantitative trait loci(QTLs),which are associated with hull thickness and color,respectively.The two QTLs were further fine mapped within intervals of 250 kb and 146 kb,respectively.These resources provide a platform for evolutionary studies and will facilitate molecular breeding of this important crop. | Chao Guo Yanan Wang Aiguo Yang Jun He Chaowen Xiao Shanhua Lv Fengming Han Yibing Yuan Yuan Yuan Xiaolong Dong Juan Guo YawenYang-Hailan Liu Ningzhi Zuo Yaxi Hu Kangxu Zhao Zhengbo Jiang Xing Wang Tingting Jiang Yaou Sherf Moju Cao Yuan Wang Zhaobo Long Tingzhao Rong Luqi Huang Shufeng Zhou | 2020 | Molecular Plant2020，13，2： | 11 |
| 17 | BRAFV600E mutation is not a positive predictor for distant metastasis in sporadic papillary thyroid carcinoma显示文摘 | JING Fan-jing LIANG Jun LIANG Zhi-yong MENG Chao LONG Wen LI Xiao-yi LIN Yan-song | 2013 | Chinese Medical Journal2013，，16： | 11 |
| 18 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis显示文摘 | Huang Norden E. Shen Zheng Long Steven R. Wu Manli C. Shih Hsing H. Zheng Quanan Yen Nai-Chyuan Tung Chi Chao Liu Henry H | 1998 | Proceedings of the Royal Society A: Mathematical Physical and Engineering Sciences1998，，1971： | 10 |
| 19 | A new frame-shifting mutation of UGT1A1 gene causes type I Crigler-Najjar syndrome显示文摘我们在场在一个维吾尔族人婴儿男孩的严重坚持的 unconjugated hyperbilirubinemia 的一个案例,当他 UGT1A1 基因顺序的血的 Crigler-Najjar 症候群类型 I.DNA 分析证明他为与框架移动引起编码 exons 的一个变化的一个插入变化是同型结合的,最后诊断了,在他他的父母的肝的 bilirubin uridine diphosphoglucuronyl transferase enzyme.Both 导致 27 | WANG Jin FANG Ling-juan LI Long WANG Jian-she CHEN Chao | 2011 | Chinese Medical Journal2011，，23： | 10 |
| 20 | Interleukin-22 contributes to liver regeneration in micewith concanavalin A-induced hepatitis after hepatectomy显示文摘AIM: To investigate the therapeutic effects and mechanisms of interleukin(IL)-22 in liver regeneration in mice with concanavalin A(Con A)-induced liver injury following 70% hepatectomy.METHODS: Mice were injected intravenously with Con A at 10 μg/g body weight 4 d before 70% hepatectomy to create a hepatitis model, and recombinant IL-22 was injected at 0.125 μg/g body weight 30 min prior to 70% hepatectomy to create a therapy model. Control animals received an intravenous injection of an identical volume of normal saline.RESULTS: IL-22 treatment prior to 70% hepatectomy performed under general anesthesia resulted in reductions in the biochemical and histological evidence of liver injury, earlier proliferating cell nuclear antigen expression and accelerated recovery of liver mass. IL-22 pretreatment also significantly induced signal transducer and activator of transcription factor 3(STAT3) activation and increased the expression of a variety of mitogenic proteins, such as Cyclin D1. Furthermore, alpha fetal protein m RNA expression was significantly elevated after IL-22 treatment.CONCLUSION: In this study, we demonstrated that IL-22 is a survival factor for hepatocytes and prevents and repairs liver injury by enhancing pro-growth pathways via STAT3 activation. Treatment with IL-22 protein may represent a novel therapeutic strategy for preventing liver injury in patients with liver disease who have undergone hepatectomy. | Ya-Min Zhang Zi-Rong Liu Zi-Lin Cui Chao Yang Long Yang Yang Li Zhong-Yang Shen | 2016 | World Journal of Gastroenterology2016，22，6： | 9 |
您所在的机构暂未开通此部分的功能，请联系管理员