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| 1 | Clarifying sub-genomic positions of QTLs for flowering habit and fruit quality in U.S. strawberry (Fragaria×ananassa) breeding populations using pedigree-based QTL analysis显示文摘The cultivated strawberry(Fragaria×ananassa)is consumed worldwide for its flavor and nutritional benefits.Genetic analysis of commercially important traits in strawberry are important for the development of breeding methods and tools for this species.Although several quantitative trait loci(QTL)have been previously detected for fruit quality and flowering traits using low-density genetic maps,clarity on the sub-genomic locations of these QTLs was missing.Recent discoveries in allo-octoploid strawberry genomics led to the development of the IStraw90 single-nucleotide polymorphism(SNP)array,enabling high-density genetic maps and finer resolution QTL analysis.In this study,breeder-specified traits were evaluated in the Eastern(Michigan)and Western(Oregon)United States for a common set of breeding populations during 2 years.Several QTLs were validated for soluble solids content(SSC),fruit weight(FWT),pH and titratable acidity(TA)using a pedigree-based QTL analysis approach.For fruit quality,a QTL for SSC on linkage group(LG)6A,a QTL for FWT on LG 2BII,a QTL for pH on LG 4CII and two QTLs for TA on LGs 2A and 5B were detected.In addition,a large-effect QTL for flowering was detected at the distal end of LG 4A,coinciding with the FaPFRU locus.Marker haplotype analysis in the FaPFRU region indicated that the homozygous recessive genotype was highly predictive of seasonal flowering.SNP probes in the FaPFRU region may help facilitate marker-assisted selection for this trait. | Sujeet Verma Jason D Zurn Natalia Salinas Megan M Mathey Beatrice Denoyes James F Hancock Chad E Finn Nahla V Bassil Vance M Whitaker | 2017 | Horticulture Research2017，4，1： | 10 |
| 2 | Case of hepatocellular carcinoma in a patient with hereditary tyrosinemia in the post-newborn screening era显示文摘Hereditary tyrosinemia type 1(HT-1) is a metabolic disorder caused by a defect in tyrosine degradation. Without treatment, symptoms of hepatomegaly, renal tubular dysfunction, growth failure, neurologic crises resembling porphyrias, rickets and possible hepatocellular carcinoma can develop. The use of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione and early diagnosis through newborn screening initiatives have resulted in a sharp decline in morbidity and mortality associated with this disease. We present a case report of a 7-year-old patient with HT-1 who was born prior to the addition of tyrosinemia to the newborn screening in her birth area. At her time of diagnosis, the patient had developed many of the symptoms associated with her disease, including chronic kidney disease, rickets, and myopathy that left her non-ambulatory. During her initial evaluation, she was also noted to have hepatocellular carcinoma. With cadaveric liver transplantation and nutritional support, her symptoms all either resolved or stabilized. Her case il ustrates the severity of the disease if left untreated, the need for vigilance in populations who do not routinely receive newborn screens, and the markedly improved outcomes in patients following transplant. | Essam M Imseis John S Bynon Chad Thornhill | 2017 | World Journal of Hepatology2017，9，9： | 2 |
| 3 | Landscape features and weather influence nest survival of a ground-nesting bird of conservation concern,the greater sage-grouse,in humanaltered environments显示文摘Introduction:Ground-nesting birds experience high levels of nest predation.However,birds can make selection decisions related to nest site location and characteristics that may result in physical,visual,and olfactory impediments to predators.Methods:We studied daily survival rate[DSR]of greater sage-grouse(Centrocercus urophasianus)from 2008 to 2010 in an area in Wyoming experiencing large-scale alterations to the landscape.We used generalized linear mixed models to model fixed and random effects,and a correlation within nesting attempts,individual birds,and years.Results:Predation of the nest was the most common source of nest failure(84.7%)followed by direct predation of the female(13.6%).Generally,landscape variables at the nest site(≤30 m)were more influential on DSR of nests than features at larger spatial scales.Percentage of shrub canopy cover at the nest site(15-m scale)and distances to natural gas wells and mesic areas had a positive relationship with DSR of nests,whereas distance to roads had a negative relationship with DSR of nests.When added to the vegetation model,maximum wind speed on the day of nest failure and a 1-day lag in precipitation(i.e.,precipitation the day before failure)improved model fit whereby both variables negatively influenced DSR of nests.Conclusions:Nest site characteristics that reduce visibility(i.e.,shrub canopy cover)have the potential to reduce depredation,whereas anthropogenic(i.e.,distance to wells)and mesic landscape features appear to facilitate depredation.Last,predators may be more efficient at locating nests under certain weather conditions(i.e.,high winds and moisture). | Stephen L Webb Chad V Olson Matthew R Dzialak Seth M Harju Jeffrey B Winstead Dusty Lockman | 2012 | Ecological Processes2012，1，1： | 2 |
| 4 | Using events as a mapping concept that complement existing ROS methods显示文摘 | Chad D PierskaUaa Jason M Siniscalchia Steven W Selina | 2007 | Leisure Sciences2007，29，1： | 1 |
| 5 | First Flush Concepts for Suspended and Dissolved Solids in Small Impervious Water-sheds显示文摘 | John J Sansalone Chad M Cristina | 2004 | Journal of Environmental Engineering2004，130，11： | 1 |
| 6 | Stratigraphic controls on vertical fracture patterns in Silarian dolomite,northeastern Wisconsin显示文摘 | Chad A Underwood M L Cooke J A | 2003 | AAPG Bulletin2003，87，1： | 1 |
| 7 | Ecological foot- print time series of Austria, the Phil- ippines, and South Korea for 1961--1999: Comparing the conventional ap- proach to ' actual land area' approach显示文摘 | Wackernagel M Chad M Erb K H | 2004 | Land Use Policy2004，21，3： | 1 |
| 8 | Perineural dexme- detomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hy- perpolarization-activated cation current显示文摘 | Chad M Brummett Elizabeth K | 2011 | Anesthesiology2011，115，4： | 1 |
| 9 | Strategies for the construction of supramolecular compounds through coordination chemistry显示文摘 | Chad A M | 2000 | Angew Chem Int Ed2000，40，： | 1 |
| 10 | 显示文摘 | Trewyn Brian G Whitman Chad M Lin Victor S Y | 2004 | Nanoletters2004，11，4： | 1 |
| 11 | First flush concepts for suspended and dissolved solids in small impervious watersheds显示文摘 | John J S Chad M C | 2004 | Journal of Environmental Engineering2004，130，： | 1 |
| 12 | Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease 显示文摘 | Moorhead JF Chad MK El-nabas M | 1982 | Lancet1982，2，8311： | 1 |
| 13 | Extraction and analysis of trifluoroacetic acid in environmental waters显示文摘 | Chad E Wujcik Thomas M Cahill | | 0，，： | 1 |
| 14 | Effects of six-week clarithromycin therapy in corticosteroid-dependent asthma :a randomized,double-blind,placebo-controlled pilot study 显示文摘 | GOTFRIED M H ROSE J CHAD R M | 2004 | Cuit Ther Res2004，65，2： | 1 |
| 15 | Continuum thermodynamics of ferroelectric domain evolution: Theory, finite ele- ment implementation, and application to domain wall pinning显示文摘 | Su Y Landis Chad M | 2007 | J Mech Phys Solids2007，55，： | 1 |
| 16 | Determination of trifluoroacetic acid in 1996-1997 precipitation and surface waters in California and Nevada显示文摘 | Chad E Wujcik Thomas M Cahill | | 0，，： | 1 |
| 17 | Why do Internet commerce firms in-corporate logistics service providers in their distributionchannels-显示文摘 | Elliot R CHAD M M | 2007 | Journal of operations management2007，25，3： | 1 |
| 18 | Electrospun Nanofibrous Polyurethane Membrane as Wound Dressing 显示文摘 | KHIL M S CHAD I KIM H Y | 2003 | Journal of Biomedical Material Research Part B2003，67，2： | 1 |
| 19 | Ecological footprint time series of Austria,the Philippines,and South Korea for 1961-1999:comparing the conventional approach to an 'actual land area' approach显示文摘 | Mathis W Chad M Karl H B Helmut H Niels N B Schulz B | 2004 | Land Use Policy2004，21，： | 1 |
| 20 | What Makes Bloggers Share Knowledge? An In- vestigation on the Role of Trust 显示文摘 | Chad S Kim M | 2010 | International Journal of In- formation Management2010，30，5： | 1 |
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