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4篇 您的检索式:作者名="Carlson TH"
    题名 作者 年代 出处 被引量
1Zinc protoporphyrin/heme ratio for diagnosis of preanemic iron deficiency显示文摘Rettmer RL Carlson TH Origenes ML 1999Pediatrics1999,104,3:1
2Reconstitution and imaging of a membrane protein in a nanometersize phospholipid bilayer显示文摘Bayburt TH Carlson JW Sligar SG 1998J Struet Biol1998,123,1:1
3Vascular Endothelial Growth Factor (VEGF)—A Possible Mediator of Inflammation and Mucosal Permeability in Patients with Collagenous Colitis显示文摘Yesuf Taha Yngve Raab Anders Larsson Marie Carlson Lars L??f Bengt Gerdin Magnus Th?rn 2004Digestive Diseases and Sciences2004,,1:1
4Steroids reduce local inflammatory mediator secretion and mucosal permeability in collagenous colitis patients显示文摘AIM: To study the effect of oral steroids upon clinical response and rectal mucosa secretion of eosinophil cationic protein (ECP), myeloperoxidase (MPO), basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and albumin in patients with collagenous colitis (CC). METHODS: A segmental perfusion technique was used to collect perfusates from rectum of CC patients once before and twice (one and four weeks) after the start of steroid treatment. Clinical data was monitored and ECP, MPO, bFGF, VEGF and albumin concentrations were analyzed by immunochemical methods in perfusates and in serum. RESULTS: Steroids reduced the number of bowel movements by more than five times within one week and all patients reported improved subjective well- being at wk 1 and 4. At the same time, the median concentrations of ECP, bFGF, VEGF and albumin in rectal perfusates decreased significantly. MPO values were above the detection limit in only 3 patients before treatment and in none during treatment. VEGF, bFGF, ECP and albumin concentrations correlated with each other with the exception of ECP and albumin. A decrease of serum ECP and VEGF concentrations was also seen even if the overtime reduction was not significant.CONCLUSION: Oral steroid treatment in CC patients induced a simultaneous reduction of bowel movements and rectal release of ECP, bFGF, VEGF and albumin, suggesting that these polypeptides and increased mucosal permeability are important components of the pathophysiology in collagenous colitis.Yesuf Taha Yngve Raab Marie Carlson Anders Larsson Mikael Lrdal Lars Lf Magnus Thrn 2006World Journal of Gastroenterology2006,12,43:0
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