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| 1 | Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study显示文摘 | JT Moller P Cluitmans LS Rasmussen P Houx H Rasmussen J Canet P Rabbitt J Jolles K Larsen CD Hanning O Langeron T Johnson PM Lauven PA Kristensen A Biedler H van Beem O Fraidakis JH Silverstein JEW Beneken JS Gravenstein | 1998 | The Lancet . 1998 (9106)1998，，9106： | 2 |
| 2 | Hepatitis B surface antigen and hepatitis B core-related antigen kinetics after adding pegylated-interferon to nucleos(t)ids analogues in hepatitis B e antigen-negative patients显示文摘BACKGROUND Hepatitis B e antigen-negative chronic hepatitis B patients under nucleos(t)ids analogues(NAs)rarely achieve hepatitis B surface antigen(HBsAg)loss.AIM To evaluate if the addition of pegylated interferon(Peg-IFN)could decrease HBsAg and hepatitis B core-related antigen(HBcrAg)levels and increase HBsAg loss rate in patients under NAs therapy.METHODS Prospective,non-randomized,open-label trial evaluating the combination of Peg-IFN 180μg/week plus NAs during forty-eight weeks vs NAs in monotherapy.Hepatitis B e antigen-negative non-cirrhotic chronic hepatitis B patients of a tertiary hospital,under NAs therapy for at least 2 years and with undetectable viral load,were eligible.Patients with hepatitis C virus,hepatitis D virus or human immunodeficiency virus co-infection and liver transplanted patients were excluded.HBsAg and HBcrAg levels(log10 U/mL)were measured at baseline and during ninety-six weeks.HBsAg loss rate was evaluated in both groups.Adverse events were recorded in both groups.The kinetic of HBsAg for each treatment group was evaluated from baseline to weeks 24 and 48 by the slope of the HBsAg decline(log10 IU/mL/week)using a linear regression model.RESULTS Sixty-five patients were enrolled,61%receiving tenofovir and 33%entecavir.Thirty-six(55%)were included in Peg-IFN-NA group and 29(44%)in NA group.After matching by age and treatment duration,baseline HBsAg levels were comparable between groups(3.1 vs 3.2)(P=0.25).HBsAg levels at weeks 24,48 and 96 declined in Peg-IFN-NA group(-0.26,-0.40 and-0.44)and remained stable in NA group(-0.10,-0.10 and-0.10)(P<0.05).The slope of HBsAg decline in Peg-IFN-NA group(-0.02)was higher than in NA group(-0.00)(P=0.015).HBcrAg levels did not change.Eight(22%)patients discontinued Peg-IFN due to adverse events.The HBsAg loss was achieved in 3(8.3%)patients of the Peg-IFN-NA group and 0(0%)of the NA group.CONCLUSION The addition of Peg-IFN to NAs caused a greater and faster decrease of HBsAg levels compared to NA therapy.Side effects of Peg-IFN can limit its use in clinical practice. | Teresa Broquetas Montserrat Garcia-Retortillo Miquel Mico Lidia Canillas Marc Puigvehi Nuria Canete Susana Coll Ana Viu Juan Jose Hernandez Xavier Bessa JoseA Carrion | 2020 | World Journal of Hepatology2020，12，11： | 2 |
| 3 | Piezoresistivity of heterogeneous solids 显示文摘 | Carnoma F Canet R Delhaes P | 1987 | Journal of Applied Physics1987，61，7： | 2 |
| 4 | Changes in physical, chemical and physico-chemical parameters during the composting of municipal solid wastes in two plants in Valencia显示文摘 | Canet R Pomares F | 1995 | Bioresource Technology1995，51，： | 2 |
| 5 | Early postoperative arterial oxygen desaturation显示文摘 | Canet J Ricos M Vidal F | 1989 | Anesth Analg1989，69，2： | 1 |
| 6 | Impact of prone surgical positioning on the scoliotic spine显示文摘 | Driscoll CR Aubin C Canet F | 2012 | J Spinal Disord Tech2012，25，3： | 1 |
| 7 | A neural network method for the analysis of multilayered shielded microwave circuits显示文摘 | Juan Pascual Garcia Fernando Quesada Perira David Canete Rebenaque | 2006 | IEEE Transactions on Microwave Theory and Techniques2006，54，1： | 1 |
| 8 | Prediction of postoperativepulmonary complications in a population-based surgical cohort显示文摘 | Canet J Gallart L Gomar C | 2010 | Anesthesiology2010，113，6： | 1 |
| 9 | Profiling posttransplant circulating antibodies in kidney transplantation using donor endothelial cells显示文摘 | Canet E Devallière J Gérard N | 2012 | Transplantation2012，93，3： | 1 |
| 10 | Agdcultural use of sediments from the Albufera Lake(eastern Spain)显示文摘 | Canet R Chaves C Pomares F | 2003 | Agriculture Ecosystems and Environment2003，95，： | 1 |
| 11 | Effectiveness and long-term results of laparoscopic common bile duct exploration显示文摘 | Riciardi R Islam S Canete JJ | 2003 | Surg Endosc2003，，： | 1 |
| 12 | Insecticidal properties of mushroom and toadstool carpophoresI显示文摘 | Norman Mier Sandrine Canete Alain Klaebe | 1996 | Phytochemrst- ry1996，41，5： | 1 |
| 13 | Cognitive dysfunction after minor surgery in the elderly 显示文摘 | Canet J Raeder J Rasmussen LS | 2003 | Acta Anaesthesiol Stand2003，47，10： | 1 |
| 14 | Prediction of postoperative pulmonary complications in a population-based surgical cohort显示文摘 | Canet J Gallart L Gomar C | | 0，，： | 1 |
| 15 | Innovation in coronary artery dis- ease and heart failure : clinical benefits of pure heart rate reduction with ivabradine显示文摘 | Canet E Lerebours G Vilaine JP | 2011 | Ann N Y Acad Sci2011，1222，： | 1 |
| 16 | Effectiveness and long-term results of laparoscopic common bile duct exploration显示文摘 | Rieiardi R Islam S Canete JJ | 2003 | Surg Endosc2003，17，1： | 1 |
| 17 | Effectiveness and long- term results of laparoseopic common bile duct exploration 显示文摘 | Riciardi R Islam S Canete JJ etal | 2003 | Surg Endosc2003，17，1： | 1 |
| 18 | Early postoperative arterial oxygen desaturation determining factors and response to oxygen therapy 显示文摘 | Ricos M Vidal F | 1989 | Anesth Analg1989，69，： | 1 |
| 19 | Influence of deformation rate and degree of compression on textural parameters of potato and apple tissues in texture profile analysis显示文摘 | ALVAREZ M D CANET W LOPEZ M E | 2002 | Eur Food Res Technol2002，215，5： | 1 |
| 20 | Influence of deformation rate and degree of compression on textural parameters of potato and apple tissue in texture profile analysis显示文摘 | Alvarez M D Canet W Lopez M E | 2002 | Europe Food Research and Technology2002，215，1： | 1 |
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