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21篇 您的检索式:作者名="Calcagno D"
    题名 作者 年代 出处 被引量
1Vascular endothelial growth factor stimulates organ2specific host mat rix metalloproteinase-9 expression and ovarian cancer invasion显示文摘Belotti D Calcagno C Garofalo A 2008Mol Cancer Res2008,6,4:1
2Clinical response to Thalidomide and colchicine in two siblings with Behcet’s disease carrying a single mutated MEFV allele显示文摘Rigante D La Torre F Calcagno G A 2012Rheumatol Int2012,32,6:1
3Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics显示文摘Calcagno A M Salcido C D Gillet J P 2010J Natl Cancer Inst2010,102,21:1
4Brcal breast tumours contain distinct CD44+/CD24 and CD133^+ cells with cancer stem cell characteristics显示文摘Wright M H Calcagno A M Salcido C D 2008Breast Cancer Res2008,10,:1
5Brca1 breast tumors contain distinct CD44+/CD24-and CD133+ cells with cancer stem cell characteristics显示文摘Wright M H Calcagno A M Salcido C D 2008Breast Cancer Res2008,10,1:1
6Clinical response to thalidomide and colchicine in two siblings with Behcet's disease carrying a single mutated MEFV allele显示文摘Rigante D La Torre F Calcagno G 2012Rheumatol Int2012,32,6:1
7Abdominal aortic aneurysm surgery: the basic evaluation of cardiac risk显示文摘Perry MO Calcagno D 1998Ann Surg1998,208,7:1
8Breal breast tumors eontain distinct CD44^+/CD24 and CD133^+ eells with eaneer stem cell characteristics显示文摘Wright M H Calcagno A M Saleido C D 2008Breast Cancer Res2008,10,1:1
9High-fat feeding stimulates endocrine, glucose-dependent insalinotropie polypeptide (GIP)- expressing cell hyperplasia in the duodenum of Wistar rats 显示文摘Gniuli D Calcagno A Dalla L 2010Diabetologia2010,53,10:1
10Glutamate and glutathione interplay in a motor neuronal model of amyotrophic lateral sclerosis reveals altered energy metabolism 显示文摘D'Alessandro G Calcagno E Tartari S 2011Neurobiol Dis2011,43,2:1
11Semiautomatic permeance tester for thick magnetic films显示文摘Calcagno P A Thompson D A 1975Rev Sci Instrurn1975,46,:1
12Brca1 breast tumors contain distinct CD44+/CD24-and CD133+ cells with cancer stem cell characteristics显示文摘Wright M H Calcagno A M Salcido C D 2008Breast Cancer Res2008,10,1:1
13Brcalbreast tumors contain distinct CD44 + /CD24 - andCD133 + cells with cancer stem cell characteristics 显示文摘Wright M H Calcagno A M Salcido C D al 2008Breast Cancer Res2008,10,1:1
14Aortic pseudoaneurysm from aortic penetration with a bird's nest vena cava filter显示文摘Campbell JJ Calcagno D 0,,03:1
15Vascular endothelial growth factor stimulates organ-specific host matrix metalloproteinase-9 expression and ovarian cancer invasion显示文摘Belotti D Calcagno C Garofalo A 2008Mol Cancer Res2008,6,4:1
16Vascular endothelial growth factor stimulates organ-specific host matrix metallopro- teinase-9 expression and ovarian cancer invasion 显示文摘Belotti D Calcagno C Garofalo A 2008Mol Cancer Res2008,6,4:1
17High plant diversity is needed to maintain ecosystem services显示文摘Isbell F Calcagno V Hector A Connolly J Harpole WS Reich PB Scherer-Lorenzen M Schmid B Tilman D van Ruijven J Weigelt A Wilsey B J Zavaleta ES Loreau M 0,,:1
18Brca1 breast tumors contain distinct CD44+/CD24-and CD133+ cells with cancer stem cell characteristics显示文摘Wright M H Calcagno A M Salcido C D 2008Breast Cancer Res2008,10,1:1
19Effects of High-fat Diet Exposure During Fetal Life on Type 2 Diabetes Development in the Progeny显示文摘Gniuli D Calcagno A Caristo ME 2008J Lipid Res2008,49,9:1
20FOLFOXIRI vs FOLFIRINOX as first-line chemotherapy in patients with advanced pancreatic cancer: A population-based cohort study显示文摘BACKGROUND FOLFIRINOX regimen is the first-line reference chemotherapy(L1)in advanced pancreatic ductal adenocarcinoma(aPDAC).FOLFOXIRI,a schedule with a lower dose of irinotecan and no bolus 5-fluorouracil,has demonstrated efficacy and feasibility in colorectal cancer.AIM To investigate the potential clinical value of FOLFOXIRI in patients with aPDAC in routine clinical practice.METHODS Analyses were derived from all consecutive aPDAC patients treated in L1 between January 2011 and December 2017 in two French institutions,with either FOLFOXIRI(n=165)or FOLFIRINOX(n=124)regimens.FOLFOXIRI consisted of irinotecan(165 mg/m2),oxaliplatin(85 mg/m2),leucovorin(200 mg/m2)and 5-fluorouracil(3200 mg/m2 as a 48-h continuous infusion)every 2 wk.Ninety-six pairs of patients were selected through propensity score matching,and clinical outcomes of the two treatment regimens were compared.RESULTS Median overall survival was 11.1 mo in the FOLFOXIRI and 11.6 mo in the FOLFIRINOX cohorts,respectively.After propensity score matching,survival rates remained similar between the two regimens in terms of overall survival(hazard ratio=1.22;P=0.219)and progression-free survival(hazard ratio=1.27;P=0.120).The objective response rate was 37.1%in the FOLFOXIRI group vs 47.8%in the FOLFIRINOX group(P=0.187).Grade 3/4 toxicities occurred in 28.7%of patients in the FOLFOXIRI cohort vs 19.5%in the FOLFIRINOX cohort(P=0.079).FOLFOXIRI was associated with a higher incidence of grade 3/4 digestive adverse events.Hematopoietic growth factors were used after each chemotherapy cycle and the low hematological toxicity rates were below 5%with both regimens.CONCLUSION FOLFOXIRI is feasible in L1 in patients with aPDAC but does not confer any therapeutic benefit as compared with FOLFIRINOX.The low hematological toxicity rates strengthened the relevance of primary prophylaxis with hematopoietic growth factors.Angélique Vienot Hortense Chevalier Clément Bolognini Elisabeta Gherga Elodie Klajer Aurélia Meurisse Marine Jary Stefano Kim Christelle d’Engremont Thierry Nguyen Fabien Calcagno Hamadi Almotlak Francine Fein Meher Nasri Syrine Abdeljaoued Anthony Turpin Christophe Borg Dewi Vernerey 2020World Journal of Gastrointestinal Oncology2020,12,3:0
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