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| 1 | Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation显示文摘The objectives of this study were to(1) determine the distribution and synthesis of pericellular matrix(PCM) molecules(collagen VI, collagen IV and laminin) in rat temporomandibular joint(TMJ) and(2) investigate the effects of PCM molecules on chondrocytes against inflammation in osteoarthritis. Four zones(fibrous, proliferating, mature and hypertrophic) of condylar cartilage and three bands(anterior, intermediate and posterior) of disc were analysed by immunohistochemistry for the presence of PCM molecules in rat TMJs. Isolated chondrocytes were pre-treated with PCM molecules before being subjected to interleukin(IL)-1β treatment to stimulate inflammation. The responses of the chondrocytes were analysed using gene expression, nitric oxide release and matrix metalloproteinase(MMP)-13 production measures. Histomorphometric analyses revealed that the highest areal deposition of collagen VI(67.4%), collagen IV(45.7%) and laminin(52.4%) was in the proliferating zone of TMJ condylar cartilage. No significant difference in the distribution of PCM molecules was noted among the three bands of the TMJ disc. All three PCM molecules were expressed intracellularly by chondrocytes cultured in the monolayer. Among the PCM molecules, pre-treatment with collagen VI enhanced cellular proliferation, ameliorated IL-1β-induced MMP-3, MMP-9, MMP-13 and inducible nitric oxide synthase gene expression, and attenuated the downregulation of cartilage matrix genes, including collagen I, aggrecan and cartilage oligomeric matrix protein(COMP). Concurrently, collagen VI pretreatment inhibited nitric oxide and MMP-13 production. Our study demonstrates for the first time the distribution and role of PCM molecules, particularly collagen VI, in the protection of chondrocytes against inflammation. | Wern Cui Chu Shipin Zhang Timothy J Sng Yu Jie Ong Wen-Li Tan Vivien Y Ang Casper B Foldager Wei Seong Toh | 2017 | International Journal of Oral Science2017，9，1： | 5 |
| 2 | 高血压患者血清磷酸盐与新发高尿酸血症风险的关系显示文摘血清磷酸盐与新发高尿酸血症的关系仍不确定。该研究对中国脑卒中一级预防试验(China stroke primary prevention trial,CSPPT)的尿酸亚组研究进行事后分析,旨在评估血清磷酸盐与新发高血尿酸症的风险之间的关系。研究包括基线尿酸水平正常(<357μmol/L)的参与者共10612人。主要观察指标是新发高血尿酸症,其定义为男性血尿酸浓度≥417或女性≥357μmol/L。在中位数为4.4年的随访期间,1663名(15.7%)参与者发生了新发高尿酸血症。 | 刘莉(译) 叶鹏(摘、审校) Cao J Zhang J Li Q Jiang C Song Y Liu C Liu L Wang B Li J Zhang Y Cui Y Huo Y Wang X Tang G Xu X Qin X | 2019 | 中华高血压杂志2019，27，6： | 2 |
| 3 | Effect of a feeding stimulant on feeding adaptation of gibel carp Carassius auratus gibelio (Bloch),fed diets with replacement of fish meal by meat and bone meal显示文摘 | Xue M Xie S Q Cui Y B | 2004 | Aquaculture Research2004，35，： | 1 |
| 4 | Passivity analysis of integro-differential neural networks with time-varying delays显示文摘 | Lou X Y Cui B T | 2007 | Neurocomputing2007，70，： | 1 |
| 5 | 显示文摘 | Cui Y B Liu C H Hu S Yu X | 2011 | Solar Energy Materials & Solar Cells2011，95，4： | 1 |
| 6 | Linkage analysis suggests a locus of ichthyosis vulgaris on lq22显示文摘 | Zhong W Cui B Zhang Y | 2003 | J Hum Genet2003，48，7： | 1 |
| 7 | A Peptides Based Cationic Liposomes Mediated Gene Delivery显示文摘 | ZHAO Y N ZHANG S B CUI S H | | 0，，01： | 1 |
| 8 | 2013, Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011显示文摘 | Qi x Cui L Jiao Y Pan Y Li X Zu R Huo X Wu B Tang F Song Y Zhou M Wang H Cardona C J Xing Z | 2013 | Archives of Virology2013，158，1： | 1 |
| 9 | MicroRNA-145:a potent tumour suppressor that regulates multiple cellular pathways显示文摘 | Cui S Y Wang R Chen L B | 2014 | J Cell Mol Med2014，18，10： | 1 |
| 10 | Transforming agriculture in China:From solely high yield to both high yield and high resource use efficiency显示文摘 | Shen J B Cui Z L Miao Y X | 2013 | Global Food Security2013，2，1： | 1 |
| 11 | A homochiral nanotubular crystalline framework of metallomacrocycles for enantioselective recognition and separation 显示文摘 | Li G Yu W B Cui Y | 2008 | J Am Chem Soc2008，130，： | 1 |
| 12 | A homochiral nanotubular crystalline framework of metallomacrocycles for enantioseleclive recognition and separation显示文摘 | Li G Yu W B Cui Y | 2008 | Journal of the American Chemical Society2008，130，14： | 1 |
| 13 | Energy budget of Nile tilapia (Oreochromis niloticus) in relation to ration size显示文摘 | Xie S Q Cui Y B Liu J K | 1997 | Aquaculture1997，154，： | 1 |
| 14 | Embedded clustering in Cr-doped A1N evidence for general behavior in dilute magnetic Ⅲ-nitride semiconductors显示文摘 | Cui X Y Fernandez-Hevia D Delley B | 2007 | J Appl Phys2007，101，10： | 1 |
| 15 | Fabricalion and interfacial modification of woodrecycled plastic composite materlals显示文摘 | Cui Y H Lee S Noruziaan B Cheung M Tao J | 2008 | Composites: Part A2008，，39： | 1 |
| 16 | Effect of a feeding stim- ulant on feeding adaptation of gibel carp Carassius au- ratus gibelio ( Bloch), fed diets with replacement of fish meal by meat and bone meal显示文摘 | XUE M XIE S Q CUI Y B | 2004 | Aquaculture Re- search2004，35，5： | 1 |
| 17 | Strong Allee effect in a diffusive predator-prey system with a protection zone显示文摘 | Cui R H Shi J P Wu B Y | 2014 | J Differential Equations2014，256，： | 1 |
| 18 | Effects of Asparagus Officinalis Extracts on Liver Cell Toxicity and Ethanol Metabolism显示文摘 | Kim B Y Cui Z G Lee S R | 2009 | J Food Sci2009，74，7： | 1 |
| 19 | TLR3signaling in macrophages is indispensable for the protective immunity of invariant natural killer T cells against enterovirus 71infection显示文摘 | Zhu K Yang J Luo K Yang C Zhang N Xu R Chen J Jin M Xu B Guo N Wang J Chen Z Cui Y Zhao H Wang Y Deng C Bai L Ge B Qin C F Shen H Yang C F Leng Q | 2015 | PLoS Pathog2015，11，10： | 1 |
| 20 | Deeolorization of azo dyes in dual-chamber biocatalyzed electrolysis systems seeding with enriched inoculum 显示文摘 | Cui D Kong F Y Liang B | 2011 | Journal of Environmental & Analytical Toxicology2011，，： | 1 |
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