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| 1 | Caveolin-1 gene silencing promotes the activation of PI3K/AKT dependent on Erα36 and the transformation of MCF10A^(CE)显示文摘ERα36,a variant of estrogen receptor-α,acts as a dominant-negative factor in both estrogen-dependent and estrogen-independent transactivation signaling pathways,and is a key factor in the promotion,progression and prognosis of breast cancers.Caveolin-1,a 22-to 24-kD integral membrane protein,may function as a tumor suppressor in inhibiting of many growth-promoting signaling pathways.It was shown that downregulation of Caveolin-1 strengthens the interaction of ERα and Caveolin-1.In conclusion,Caveolin-1 gene silencing activated the PI3K/AKT signaling pathway in an ERα36-dependent way.Our finding may provide a promising therapeutic target of breast cancer. | FENG Shuang1,WANG Yang1,WANG Xi1,WANG ZhaoYi3,CUI YuYing1,LIU Jing4,ZHAO ChunHui1,JIN Mei1,2 & ZOU Wei1,2 1 College of Life Science,Liaoning Normal University,Dalian 116029,China 2 Liaoning Key Laboratory of Biotechnology and Molecular Drug R&D,Dalian 116029,China 3 Cancer Center,Creighton University,2500 California Plaza,Omaha,NE 68178,USA 4 First Clinical Hospital of Dalian Medical University,Dalian 116011,China | 2010 | Science China(Life Sciences)2010，53，5： | 16 |
| 2 | Potent antitumor efficacy of an E1B 55kDa-deficient adenovirus carrying murine endostatin in hepatocellular carcinoma显示文摘 | Li G Sham J Yang J Su C Xue H Chua D Sun L Zhang Q Cui Z Wu M Qian Q | 2005 | 第二军医大学学报2005，26，11： | 9 |
| 3 | Distortion control of conjugacies between quadratic polynomials显示文摘We use a new type of distortion control of univalent functions to give an alternative proof of Douady-Hubbard’s ray-landing theorem for quadratic Misiurewicz polynomials. The univalent maps arise from Thurston’s iterated algorithm on perturbation of such polynomials. | CUI GuiZhen 1, & TAN Lei 2 1 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China 2 Laboratoire de Mathmatiques, UMR du CNRS 6093, Universit d’Angers, 2 bd. Lavoisier, 49045 Angers cedex 01, France | 2010 | Science China Mathematics2010，53，3： | 3 |
| 4 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 3 |
| 5 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 2 |
| 6 | Influence of Coal Nature and Structure on Ash Size Formation Characteristic and Related Pollutant Emissions During CFB Combustion显示文摘The size distribution of coal particles in a Circulating Fluidized Bed (CFB) boiler plays a crucial role in the complicated combustion, heat exchange and pollutant emissions in such a plat. Therefore, it is fundamental to study the different factors having influence on the size distribution of coal particles. Above all, the coal itself and in particular, the coal combination phenomenon is a very influent factor. In the frame of this work, the coal nature (elementary composition) and coal internal structure (mineral components) are studied in detail. At this intermediary stage, experiments on three typical Chinese coals on a l.5 MWt CFBC pilot plant have been made. Some primary fragmentation tests have also been made in a small lab scale fluidized bed reactor. The results from the hot pilot test show i) the variation of coal ash distributions and other CFB performance data due to the cyclone and the coal characteristics and ii) the variation of desulfurization efficiency with limestone. Whereas the bench scale primary fragmentation test, likely linked to the caking propriety of a coal, does not seem to change considerably the char size distribution. | Min QIAN Arnaud BOELLE Philippe JAUD ( Electricite de France Division R&D, 6 quai Watier B.P.49 78401 Chatou, France ) Yongjie NA Qinggang LU Shaolin BAO ding CUI Weihong JIAO Huanming ZHAO (Institute of Engineering Thermophysics, Chinese Academ | 2000 | Journal of Thermal Science2000，9，3： | 2 |
| 7 | Investigation of flow in a steam turbine exhaust hood with/without turbine exit conditions simulated显示文摘 | LIU J J CUI Y Q JIANG H D | 2003 | Journal of Engineering for Gas Turbines and Power2003，125，1： | 1 |
| 8 | Transfer hydrogenation of activatied C=C bonds catalyzed by ruthenium amido complexes: Reaction scope, limitation, and enantioselectivity 显示文摘 | Xue D Chen Y C Cui X | 2005 | Journal of Organic Chemistry2005，70，9： | 1 |
| 9 | Studies on CdSalen immobilized onto N-(4-pyridylmethylidene) chitosan显示文摘 | Hu D Cui Y L Dong X L | 2001 | Reactive and Functional Polymers2001，48，13： | 1 |
| 10 | Characterization of the human multi- drug resistance protein isoform MRP3 localized to the basolateral hepatocytemembrane显示文摘 | Konig J Rost D Cui Y | 1999 | Hepatolagy1999，29，4： | 1 |
| 11 | Effect of microwave-vacuum drying on the carotenoids retention of carrot slices and chlorophyll reten- tion of Chinese chive leaves显示文摘 | Cui Z W Xu S Y Sun D W | 2003 | Drying Technology2003，22，3： | 1 |
| 12 | Relations Among Notions of Security for Identity Based Encryption Schemes显示文摘 | ATTRAPADUNG N CUI Y GALINDO D | 2006 | Lect Notes Comput SC2006，3887，： | 1 |
| 13 | Physicochemical propertiesand bactericidal efficiency of neutral and acidic electrolyzed waterunder different storage conditions显示文摘 | CUI X D SHANG Y C SHI Z X | 2009 | Journal of Food Engineering2009，91，4： | 1 |
| 14 | Com porous starch :Preparation,characterization and adsorption property显示文摘 | Zhang B Cui D Liu M | 2012 | International Journal of Biological Macromole-cules2012，50，1： | 1 |
| 15 | Peer relationship and suicide ideation and attempts among Chinese adolescents显示文摘 | Cui S Cheng Y Chen D | 2011 | Child Care Health Dev2011，37，5： | 1 |
| 16 | Computational prediction of human proteins that can be secreted into the bloodstream 显示文摘 | Cui J Liu Q Puett D | 2008 | Bioinformatics2008，25，20： | 1 |
| 17 | Ligands Dominate Highly Syndioselective Polymerization of Styrene by Using Constrained-geometry-configuration Rare-earth Metal Precursors显示文摘 | Pan Y P Rong W F Cui D M | | 0，，03： | 1 |
| 18 | Secure and efficient localization scheme in ultra-wideband sensor networks显示文摘 | He D J Cui L Huang H J | | 0，，04： | 1 |
| 19 | A computational improvement to the dynamic programming algorithm for the optimal cutting of equal rectangles显示文摘 | Cui Y D | | 0，，03： | 1 |
| 20 | Enzymatic epoxidationof Sapindus mukurossi seed oil by perstearic acid optimizedusing response surface methodology 显示文摘 | SUN S D KE X Q CUI L I | 2011 | Industrial Crops Prod-ucts2011，33，3： | 1 |
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