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| 1 | Endoscopy in inflammatory bowel disease: Role in diagnosis, management, and treatment显示文摘Endoscopy plays a fundamental role in the diagnosis, management, and treatment of inflammatory bowel dis-ease(IBD). Colonoscopy, flexible sigmoidoscopy, and esophagogastroduodenoscopy have long been used in the care of patients with IBD. As endoscopic technologies have progressed, tools such as endoscopic ultrasound, capsule endoscopy, and balloon-assisted enteroscopy have expanded the role of endoscopy in IBD. Furthermore, chromoendoscopy has enhanced our ability to detect dys-plasia in IBD. In this review article, we will focus on the roles, indications, and limitations of these tools in IBD. We will also discuss the most commonly used endoscopic scoring systems, as well as special considerations in post-surgical patients. Lastly, we will discuss the role of endoscopy in the diagnosis and management of fistulae and strictures. | Clayton M Spiceland Nilesh Lodhia | 2018 | World Journal of Gastroenterology2018，24，35： | 23 |
| 2 | 肝癌乙型肝炎病毒X抗原相关基因的克隆显示文摘目的 观察HepG2细胞因乙型肝炎病毒X抗原 (HBx)转染导致的基因表达差异。 方法①用逆转录病毒感染的方法建立表达乙型肝炎病毒X抗原 (HepG2X)及氯霉素乙酰转移酶 (HepG2Cat)的细胞模型。②用抑制差减杂交的方法做HepG2X和对照细胞 (HepG2Cat)的cDNA文库差示筛选。③用3 2 P随机引物标记法标记探针做NorthernBlot杂交及地高辛缺口翻译标记法做原位分子杂交以筛选基因探针。结果 经cDNA文库差减杂交及抑制性PCR扩增共得到 10个cDNA探针 ,其中 8个被HBx所启动 ,2个因HBx而表达下降。经检测 ,这些基因在HepG2X和对照细胞中的表达均有差异。在被HBx所抑制的 2个差示表达基因中 ,1个与人的蛋白翻译起始因子同源 ,同时发现 ,此基因在正常组织中表达较强 ,而在肿瘤组织中表达被抑制。结论 HBx能够改变宿主细胞的基因表达 。 | 刘杰 LIAN Zhaorui PAN Jinbo Clayton M 胡家露 朱明华 窦科峰 丁杰 吴开春 樊代明 Feitelson M | 2000 | 中华消化杂志2000，20，3： | 7 |
| 3 | 近期呼吸道感染与心血管疾病风险间关系初探显示文摘 | Clayton TC Thompson M Meade TW 袁志敏(摘译) 刘运德(校) | 2008 | 心血管病学进展2008，29，5： | 2 |
| 4 | Increased CD3 lymphocytes and inos :further evidence of an inflammatory response in irritable bowelsyndrome显示文摘 | Osullivan M Clayton N Wong T | 2000 | Gut2000，47，3： | 2 |
| 5 | Modeling flight activity and population dynamics of the pine engraver, Ips pini, in the Great Lakes region: effects of weather and predators over short time scales显示文摘 | Aukema B H Clayton M K Raffa K F | 2005 | Population Ecology2005，47，1： | 1 |
| 6 | The Impact of CEO Turnover on Equity Volatility 显示文摘 | Clayton M C Hartzell J C Rosenberg J | 2005 | Journal of Business2005，，78： | 1 |
| 7 | Liver-specific RNA metabolism in hepatoma cells:variations in transcription rates and mRNA levels显示文摘 | Clayton DF Weiss M Darnell JE | 1985 | Molecular Cellular Biology1985，5，： | 1 |
| 8 | Experimental investigations of ligamentous healing 显示文摘 | Clayton ML Miles JS Abdulla M | 1968 | Clin Orthop Relat Res1968，61，： | 1 |
| 9 | Post - transcriptional regulation of geneexpression in trypanosomes and leishmanias 显示文摘 | Clayton C Shapira M | 2007 | Mol BiochemParasitol2007，156，2： | 1 |
| 10 | Topical negative pressure stimulates endothelial migration and proliferation: a suggested mechanism for improved integration of integra显示文摘 | Baldwin C Potter M Clayton E | 2009 | Ann Plast Surg2009，62，1： | 1 |
| 11 | Application of geostatistics to characterize leaf area index (LAI) from flux tower to landscape scales using a cyclic sampling design显示文摘 | Burrows S N Gower S T Clayton M K | 2005 | Ecosystems2005，5，： | 1 |
| 12 | A randomized controlled trim of laser treatment among hirsute women with polycystic ovarysyndrome显示文摘 | Clayton WJ Lipton M Elford J | 2005 | Br J Dermatol2005，152，5： | 1 |
| 13 | A statistical evaluation of animal and nutrional factors influencing concentrations of milk urea ni- trogen显示文摘 | Broderick G A Clayton M C | 1997 | J Dairy Sci1997，80，： | 1 |
| 14 | Debt Investment, and Product Market Competition : A Note on the Limited Liability Effect 显示文摘 | Clayton M J | 2009 | Journal of Banking & Finance2009，33，4： | 1 |
| 15 | HIV is a virus,not a crime显示文摘 | Cameron E Burds S Clayton M | 2008 | HIV AIDS Policy Law Rev2008，13，64： | 1 |
| 16 | Comparison of a new colorimetric assay with the NCCLS broth microdilution method(M27-A) for antifungal drug MIC determination显示文摘 | LI R K ELIE C M CLAYTON G E | 2000 | J Clin Microbiol2000，38，6： | 1 |
| 17 | Reinventing Your Business Model 显示文摘 | Mark W Johnson Clayton M Christensen Henning Kagermann | 2008 | Harvard Business Review2008，，12： | 1 |
| 18 | The mechanism of galactosamine toxicity revisited;a metabonomic study显示文摘 | COEN M HONG Y S CLAYTON T A | | 0，，： | 1 |
| 19 | White on autonomy, neutrality and well- being 显示文摘 | Clayton M | 1993 | Journal of Philosophy of Education1993，27，2： | 1 |
| 20 | Solar induced currents in power system:cause and effects显示文摘 | ALBERTSON V D THORSON J M CLAYTON R E | 1973 | IEEE Transactions on Power Apparatus and System1973，92，2： | 1 |
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