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| 1 | Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16" monocyte population via the IL-10/STAT3 axis显示文摘 | Claire Lastrucci Alan Benard Luciana Balboa Karine Pingris Shanti Sourian Renaud Poincloux Talal A Saati Voahangy Rasolofo Pablo Gonzfilez-Montaner Sandra Inwentarz Eduardo Jose Morafia Ivanela Kondova Frank AW Verreck Maria del Carmen Sasiain Olivier Neyrolles Isabelle Maridonneau-Parini Geanncarlo Lugo-Villarino Ce1ine Cougoule | 2015 | Cell Research2015，25，12： | 7 |
| 2 | Genetic and phenological variation of tocochromanol(vitamin E)content in wild(Daucus carota L.var.carota)and domesticated carrot(D.carota L.var.sativa)显示文摘Carrot roots(Daucus carota L.var.sativa)produce tocochromanol compounds,collectively known as vitamin E.However,little is known about their types and amounts.Here we determined the range and variation in types and amounts of tocochromanols in a variety of cultivated carrot accessions throughout carrot postharvest storage and reproductive stages and in wild-type roots(Daucus carota L.var.carota).Of eight possible tocochromanol compounds,we detected and quantified α-,and the combined peak for β-and γ-forms of tocopherols and tocotrienols.Significant variation in amounts of tocochromanol compounds was observed across accessions and over time.Large increases in a-tocopherol were noted during both reproductive growth and the postharvest stages.The variation of tocochromanols in carrot root tissue provides useful information for future research seeking to understand the role of these compounds in carrot root tissue or to breed varieties with increased levels of these compounds. | Claire H Luby Hiroshi A Maeda Irwin L Goldman | 2014 | Horticulture Research2014，1，1： | 6 |
| 3 | Human small intestine is capable of restoring barrier function after short ischemic periods显示文摘AIM To assess intestinal barrier function during human intestinal ischemia and reperfusion(IR).METHODS In a human experimental model,6 cm of jejunum was selectively exposed to 30 min of ischemia(I) followed by 30 and 120 min of reperfusion(R). A sham procedure was also performed. Blood and tissue was sampled at all-time points. Functional barrier function was assessed using dual-sugar absorption tests with lactulose(L) and rhamnose(R). Plasma concentrations of citrulline,an amino acid described as marker for enterocyte function were measured as marker of metabolic enterocytes restoration. Damage to the epithelial lining was assessed by immunohistochemistry for tight junctions( TJs),by plasma marker for enterocytes damage(I-FABP) and analyzed by electron microscopy(EM) using lanthanum nitrate as an electrondense marker.RESULTS Plasma L/R ratio's were significantly increased after 30 min of ischemia(30 I) followed by 30 min of reperfusion(30 R) compared to control(0.75 ± 0.10 vs 0.20 ± 0.09,P < 0.05). At 120 min of reperfusion(120 R),ratio's normalized(0.17 ± 0.06) and were not significantly different from control. Plasma levels of I-FABP correlated with plasma L/R ratios measured at the same time points(correlation: 0.467,P < 0.01). TJs staining shows distortion of staining at 30 I. An intact lining of TJs was again observed at 30 I120 R. Electron microscopy analysis revealed disrupted TJs after 30 I with paracellular leakage of lanthanum nitrate,which restored after 30 I120 R. Furthermore,citrulline concentrations closely paralleled the histological perturbations during intestinal IR.CONCLUSION This study directly correlates histological data with intestinal permeability tests,revealing that the human gut has the ability of to withstand short episodes of ischemia,with morphological and functional recovery of the intestinal barrier within 120 min of reperfusion. | Dirk HSM Schellekens Inca HR Hundscheid Claire AJI Leenarts Joep Grootjans Kaatje Lenaerts Wim A Buurman Cornelis HC Dejong Joep PM Derikx | 2017 | World Journal of Gastroenterology2017，23，48： | 4 |
| 4 | Imaging of liver cancer显示文摘Improvements in imaging technology allow exploitation of the dual blood supply of the liver to aid in the identif ication and characterisation of both malignant and benign liver lesions. Imaging techniques available include contrast enhanced ultrasound, computed tomography and magnetic resonance imaging. This review discusses the application of several imaging techniques in the diagnosis and staging of both hepatocellular carcinoma and cholangiocarcinoma and outlines certain characteristics of benign liver lesions. The advantages of each imaging technique are highlighted, while underscoring the potential pitfalls and limitations of each imaging modality. | Ben Ariff Claire R Lloyd Sameer Khan Mohamed Shariff Andrew V Thillainayagam Devinder S Bansi Shahid A Khan Simon D Taylor-Robinson Adrian KP Lim | 2009 | World Journal of Gastroenterology2009，15，11： | 4 |
| 5 | Colitis cystica profunda of the rectum: An unexpected operative finding显示文摘Colitis cystic profunda is a rare entity benign condition of the colon and rectum that can mimic suspicious polyps or malignancy. The commonest sites of affectation are the rectum and the sigmoid colon but it can be unusually widely distributed in the colon. The aetiology of this condition is not fully elucidated and confident diagnosis can only be made on histological features. We hereby describe a patient who presented with significant rectal symptoms and an unexpected finding of a submucosal mucous cyst mimicking a suspicious rectal polyp and highlighted its significance and the review of the literature. | Abraham A Ayantunde Claire Strauss Malathi Sivakkolunthu Anu Malhotra | 2016 | World Journal of Clinical Cases2016，4，7： | 3 |
| 6 | Liver Fibrosis: Noninvasive Assessment with Acoustic Radiation Force Impulse Elastography—Comparison with FibroScan M and XL Probes and FibroTest in Patients with Chronic Liver Disease显示文摘 | Christophe Cassinotto Bruno Lapuyade Ania A?t-Ali Julien Vergniol Delphine Gaye Juliette Foucher Claire Bailacq-Auder Faiza Chermak Brigitte Le Bail Victor de Lédinghen | 2013 | Radiology2013，，1： | 3 |
| 7 | Outcomes of the Bowel Cancer Screening Programme (BCSP) in England after the first 1 million tests显示文摘 | Richard F A Logan Julietta Patnick Claire Nickerson Lynn Coleman Matt D Rutter Christian von Wagner | 2012 | Gut2012，，10： | 2 |
| 8 | Triterpenes and other constituents of Nassauvia axillaris显示文摘 | CLAUDIA KOTOWICZ CESAR A N CATALAN CLAIRE L GRIFFIN | 2005 | Biochemical Systematics and Ecology2005，33，： | 1 |
| 9 | The Impact of Ultraviolet-B Radiation on the Motility of the Freshwater Epipelic Diatom Nitzschia lineariz 显示文摘 | MOROZ A L EHRMAN J M CLAIR T A et d | 1999 | Global Change Biology1999，5，2： | 1 |
| 10 | Acupuncture use in the UnitedStates : findings from the National Health Interview Survey显示文摘 | Burke A Upchurch D Claire D | 2006 | J AltemComplement Med2006，12，7： | 1 |
| 11 | Dealing with discrep- ant expectations: Response strategies and managerial ef-fectiveness显示文摘 | Tsui A Ashford S Clair L | 1995 | Academy of Management Journal1995，38，6： | 1 |
| 12 | Evaluation of vibration and shock attention preformation of a suspension seat with a semi-active magneto-rheological fluid damper显示文摘 | Mcmanus S J Clair K A S Boileau P E | 2002 | Journal of Sound and Vibration2002，253，1： | 1 |
| 13 | Evaluation of vibration and shock attenuation performance of a suspension seat with a semiactive maghetorheological fluid damper显示文摘 | Mcmanus S J Clair K A S T | 2002 | Journal of Sound and Vibration2002，253，1： | 1 |
| 14 | The Effects of Microbiotic Soil Crustson Soil Water Loss显示文摘 | George D B Roundy B A Clair L L | 2003 | Arid Land Research and Management2003，17，2： | 1 |
| 15 | Circulating transforming growth factor beta 1 (TGF-betal) in Guillain-Barre syndrome : decreased concentrations in the early course and increase with motor function显示文摘 | Crange A Blec L Clair B | 1998 | J Neurol NeurosurgPsychiatry1998，64，2： | 1 |
| 16 | Determination of the oxidation states of manganese in brain, liver, and heart mitochondria 显示文摘 | Thomas E G Lisa M M Claire E G Roman E Jason S Linas B Andrei A Sean H Karlene K G | 2004 | Journal of Neuroehemistry2004，88，： | 1 |
| 17 | Genome-wide Analysis of Arabidpopsis Pentatricopetide Repeat Proteins Reveals their Essential Role in Organelle Biogenesis 显示文摘 | CLAIRE L CHARLES A SEBASTIEN A | 2004 | The Plant Cell2004，16，： | 1 |
| 18 | Association within a family of a balanced autosomal translocation with major mental illness显示文摘 | St Clair D Blackwood D Muir W Carothers A Walker M Spowart G Gosden C Evans H J | | 0，，8706： | 1 |
| 19 | Refraining crisis management显示文摘 | Pearson C M Clair J A | 1998 | Academy of Management Review1998，23，1： | 1 |
| 20 | CTLA4Ig: bridging the basic immunology with clinical application显示文摘 | Bluestone J A St Clair E W Turka L A | 2006 | Immunity2006，24，3： | 1 |
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