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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Treatment of peri-implant defects with guided bone regeneration:A comparative clinical study with various membranes and bone grafts显示文摘 | Martin L Christof P Clemens K | 1998 | Int J OralMaxillofac Implants1998，13，： | 1 |
| 3 | A saliency - based search mechanism for overt and covert shifts of visual attention 显示文摘 | LAURENT I CHRISTOF K | 2000 | Vision Research2000，，40： | 1 |
| 4 | Hypertonic hyperoncotic solutions reduce the release of cardiac troponin Ⅰ and S-100 after successful cardiopulmonary resuscitation in pigs 显示文摘 | Heiner K Christof D Christoph J | 2002 | Anesth Analg2002，95，： | 1 |
| 5 | A model of saliency-based visual attention for rapid scene analysis显示文摘 | Laurent I Christof K Emst N | 1998 | IEEE Transactions on Pattern Analysis and Machine Intelligence1998，20，11： | 1 |
| 6 | Health related quality of life in coronary patients and its association with their cardiovascular risk profile: Results from the EUROASPIRE III survey显示文摘 | Delphine De Smedt Els Clays Lieven Annemans Frank Doyle Kornelia Kotseva Andrzej Paj?k Christof Prugger Catriona Jennings David Wood Dirk De Bacquer | 2012 | International Journal of Cardiology2012，，： | 1 |
| 7 | A model of saliency-based visual attention for rapid scene analysis 显示文摘 | LAURENT I CHRISTOF K ERNST N | 1998 | IEEE Transactions on Pattern Analysis and Machine Intelligence1998，20，11： | 1 |
| 8 | Oil the or- igin of the extracellular action potential waveform: A modeling study显示文摘 | GOLD C HENZE D A CHRISTOF K | 2006 | Journal of Neurophysiology2006，95，5： | 1 |
| 9 | Image Signature: Highlighting Sparse Salient Regions 显示文摘 | Hou X D Jonathan H Christof K | 2012 | IEEE Trans Pattern Anal2012，34，1： | 1 |
| 10 | Modeling attention to salient proto-objects 显示文摘 | DIRK W CHRISTOF K | 2006 | Neural Networks2006，19，9： | 1 |
| 11 | Getting Groups to Develop Good Strate- gies : Effects of Reflexivity Interventions on Team Process, Team Performance, and Shared Mental Models 显示文摘 | Andrea Gurtner Franziska Tschan Norbert K Semmer Christof Ngele | 2007 | Or- ganizational Behavior and Human Decision Processes2007，102，2： | 1 |
| 12 | Randomized, double - blind, con- trolled study of glycy - 1 glutamine - dip eptide in the parenteral nutrition of patients with acute leukemia undergoing intensive chemotherapy显示文摘 | Christof S Karin H Gisela K | 2004 | Nutrition2004，20，3： | 1 |
| 13 | Image Signature: Highlighting Sparse Salient Regions 显示文摘 | Hou X D Jonathan H Christof K | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，1： | 1 |
| 14 | Advances in Digital Radiography:Physical Principles and System Overview显示文摘 | Markus K Christof HW Stefan W | 2007 | Radiograp hics2007，27，3： | 1 |
| 15 | Modes of initiation of paroxysmal atrial fibrillation from analysis of spontaneously occurring episodes using a 12-lead Holler monitoring system 显示文摘 | Christof K Susanna N Gjin N | 2001 | Am J Cardiol2001，88，： | 1 |
| 16 | A Model of Sliency-based Visual Attention for Raid Scene Analysis显示文摘 | Laurent I Christof K Ernst N | 1998 | IEEE Transactions on PAMI1998，20，11： | 1 |
| 17 | Competing dissociation channels in the photolysis of S2Clz at 235 nm显示文摘 | Einfeld T S Christof M Gerieke K H | 2002 | J Cbem Phys2002，117，9： | 1 |
| 18 | Randomized,double-blind,controlled study of glycyl-glutamine-dipeptide in the parenteral nutrition of patients with acute leukemia undergoing intensive chemotherapy显示文摘 | CHRISTOF S KARIN H GISELA K | 2004 | Nutrition2004，20，3： | 1 |
| 19 | A model of saliency-based visual attention for rapid scene analysis显示文摘 | Laurent I Christof K Emst N | 1998 | IEEE Transactions on Pattern Analysis and Machine Intelligence1998，20，11： | 1 |
| 20 | A saliency-based search mechanism for overt and covert shifts of visual attention显示文摘 | Laurent I Christof K | 2000 | Vision Research2000，40，10： | 1 |
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