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| 1 | Oxidative stress in granulosa cells contributes to poor oocytequality and IVF-ET outcomes in women with polycystic ovarysyndrome显示文摘The increased levels of intraceHular reactive oxygen species (ROS) in granulosa cells (GCs) may allectthe pregnancy results in women with polycystic ovary syndrome (PCOS). In this study, we compared the in vitrofertilization and embryo transfer (IVF-ET) results of 22 patients with PCOS and 25 patients with tubal factorinfertility and detected the ROS levels in the GCs of these two groups. Results showed that the PCOS group hadsignificantly larger follicles on the administration day for human chorionic gonadotropin than the tubal factorgroup (P 〈 0.05); however, the number of retrieved oocytes was not significantly different between the two groups(P 〉 0.05). PCOS group had slightly lower fertilization, cleavage, grade IflI embryo, clinical pregnancy, andimplantation rates and higher miscarriage rate than the tubal factor group (P 〉 0.05). We further found asignificantly higher ROS level of GCs in the PCOS group than in the tubal factor group (P 〈 0.05). The increasedROS levels in GCs caused GC apoptosis, whereas NADPH oxidase 2 (NOX2) specific inhibitors (diphenyleneio-donium and apocynin) significantly reduced the ROS production in the PCOS group. In conclusion, the increasedROS expression levels in PCOS GCs greatly induced cell apoptosis, which further affected the oocyte quality andreduced the positive IVF-ET pregnancy results of women with PCOS. NADPH oxidase pathway may be involvedin the mechanism of ROS production in GCs of women with PCOS. | Qiaohong Lai Wenpei Xiang Qing Li Hanwang Zhang Yufeng Li Guijin Zhu Chengliang Xiong Lei Jin | 2018 | Frontiers of Medicine2018，12，5： | 26 |
| 2 | Structure reveals that BAK1 as a co-receptor recognizes the BRIl-bound brassinolide显示文摘 | Yadong Sun Zhlfu Han Jiao Tang Zehan Hu Chengliang Chai Bin Zhou Jijie Chai | 2013 | Cell Research2013，23，11： | 24 |
| 3 | Design and Analysis of Electro-mechanical Hybrid Anti-lock Braking System for Hybrid Electric Vehicle Utilizing Motor Regenerative Braking显示文摘Braking on low adhesion-coefficient roads, hybrid electric vehicle's motor regenerative torque is switched off to safeguard the normal anti-lock braking system(ABS) function.When the ABS control is terminated, the motor regenerative braking is readmitted.Aiming at avoiding permanent cycles from hydraulic anti-lock braking to motor regenerative braking, a novel electro-mechanical hybrid anti-lock braking system using fuzzy logic is designed.Different from the traditional single control structure, this system has a two-layered hierarchical structure.The first layer is responsible for harmonious adjustment or interaction between regenerative system and anti-lock braking system.The second layer is responsible for braking torque distribution and adjustment.The closed-loop simulation model is built.Control strategy and method for coordination between regenerative and anti-lock braking are developed.Simulation braking on low adhesion-coefficient roads with fuzzy logic control and real vehicle braking field test are presented.The results from simulating analysis and experiment show braking performance of the vehicle is perfect, harmonious coordination between regenerative and anti-lock braking function, significant amount of braking energy can be recovered and the proposed control strategy and method are effective. | ZHANG Jianlong YIN Chengliang ZHANG Jianwu | 2009 | Chinese Journal of Mechanical Engineering2009，22，1： | 22 |
| 4 | Synthesis of novel nanomaterials and their application in efficient removal of radionuclides显示文摘With the development of nuclear energy, large amounts of radionuclides are inevitably released into the natural environment. It is necessary to eliminate radionuclides from wastewater for the protection of environment. Nanomaterials have been considered as the potential candidates for the effective and selective removal of radionuclides from aqueous solutions under complicated conditions because of their high specific surface area, large amounts of binding sites, abundant functional groups, pore-size controllable and easily surface modification. This review mainly summarized the recent studies for the synthesis, fabrication and surface modification of novel nanomaterials and their applications in the efficient elimination and solidification of radionuclides,and discussed the interaction mechanisms from batch experiments, spectroscopy analysis and theoretical calculations. The sorption capacities with other materials, advantages and disadvantages of different nanomaterials are compared, and at last the perspective of the novel nanomaterials is summarized. | Xiangxue Wang Long Chen Lin Wang Qiaohui Fan Duoqiang Pan Jiaxing Li Fangting Chi Yi Xie Shujun Yu Chengliang Xiao Feng Luo Jun Wang Xiaolin Wang Changlun Chen Wangsuo Wu Weiqun Shi Shuao Wang Xiangke Wang | 2019 | Science China Chemistry2019，62，8： | 20 |
| 5 | Emerging in-plane anisotropic two-dimensional materials显示文摘Black phosphorus(BP)is a rapidly up and coming star in two-dimensional(2D)materials.The unique characteristic of BP is its in-plane anisotropy.This characteristic of BP ignites a new type of 2D materials that have low-symmetry structures and in-plane anisotropic properties.On this basis,they offer richer and more unique low-dimensional physics compared to isotropic 2D materials,thus providing a fertile ground for novel applications including electronics,optoelectronics,molecular detection,thermoelectric,piezoelectric,and ferroelectric with respect to in-plane anisotropy.This article reviews the recent advance in characterization and applications of in-plane anisotropic 2D materials. | Liang Li Wei Han Lejing Pi Ping Niu Junbo Han Chengliang Wang Bin Su Huiqiao Li Jie Xiong Yoshio Bando Tianyou Zhai | 2019 | InfoMat2019，1，1： | 16 |
| 6 | Melatonin: A master regulator of plant development and stress responses显示文摘Melatonin is a pleiotropic molecule with multiple functions in plants. Since the discovery of melatonin in plants, numerous studies have provided insight into the biosynthesis, catabolism, and physiological and biochemical functions of this important molecule. Here, we describe the biosynthesis of melatonin from tryptophan, as well as its various degradation pathways in plants. The identification of a putative melatonin receptor in plants has led to the hypothesis that melatonin is a hormone involved in regulating plant growth,aerial organ development, root morphology, and the floral transition. The universal antioxidant activity of melatonin and its role in preserving chlorophyll might explain its anti-senescence capacity in aging leaves. An impressive amount of research has focused on the role of melatonin in modulating postharvest fruit ripening by regulating the expression of ethylene-related genes.Recent evidence also indicated that melatonin functions in the plant's response to biotic stress,cooperating with other phytohormones and wellknown molecules such as reactive oxygen species and nitric oxide. Finally, great progress has been made towards understanding how melatonin alleviates the effects of various abiotic stresses, including salt, drought, extreme temperature, and heavy metal stress. Given its diverse roles, we propose that melatonin is a master regulator in plants. | Chengliang Sun Lijuan Liu Luxuan Wang Baohai Li Chongwei Jinand Xianyong Lin | 2021 | Journal of Integrative Plant Biology2021，63，1： | 14 |
| 7 | Series-parallel Hybrid Vehicle Control Strategy Design and Optimization Using Real-valued Genetic Algorithm显示文摘Despite the series-parallel hybrid electric vehicle inherits the performance advantages from both series and parallel hybrid electric vehicle, few researches about the series-parallel hybrid electric vehicle have been revealed because of its complex construction and control strategy. In this paper, a series-parallel hybrid electric bus as well as its control strategy is revealed, and a control parameter optimization approach using the real-valued genetic algorithm is proposed. The optimization objective is to minimize the fuel consumption while sustain the battery state of charge, a tangent penalty function of state of charge(SOC) is embodied in the objective function to recast this multi-objective nonlinear optimization problem as a single linear optimization problem. For this strategy, the vehicle operating mode is switched based on the vehicle speed, and an 'optimal line' typed strategy is designed for the parallel control. The optimization parameters include the speed threshold for mode switching, the highest state of charge allowed, the lowest state of charge allowed and the scale factor of the engine optimal torque to the engine maximum torque at a rotational speed. They are optimized through numerical experiments based on real-value genes, arithmetic crossover and mutation operators. The hybrid bus has been evaluated at the Chinese Transit Bus City Driving Cycle via road test, in which a control area network-based monitor system was used to trace the driving schedule. The test result shows that this approach is feasible for the control parameter optimization. This approach can be applied to not only the novel construction presented in this paper, but also other types of hybrid electric vehicles. | XIONG Weiwei YIN Chengliang ZHANG Yong ZHANG Jianlong | 2009 | Chinese Journal of Mechanical Engineering2009，22，6： | 14 |
| 8 | OPTIMAL TORQUE CONTROL STRATEGY FOR PARALLEL HYBRID ELECTRIC VEHICLE WITH AUTOMATIC MECHANICAL TRANSMISSION显示文摘In parallel hybrid electrical vehicle (PHEV) equipped with automatic mechanical transmission (AMT), the driving smoothness and the clutch abrasion are the primary considerations for powertrain control during gearshift and clutch operation. To improve these performance indexes of PHEV, a coordinated control system is proposed through the analyzing of HEV powertrain dynamic characteristics. Using the method of minimum principle, the input torque of transmission is optimized to improve the driving smoothness of vehicle. Using the methods of fuzzy logic and fuzzy-PID, the engaging speed of clutch and the throttle opening of engine are manipulated to ensure the smoothness of clutch engagement and reduce the abrasion of clutch friction plates. The motor provides the difference between the required input torque of transmission and the torque transmitted through clutch plates. Results of simulation and experiments show that the proposed control strategy performs better than the contrastive control system, the smoothness of driving and the abrasion of clutch can be improved simultaneously. | GU Yanchun YIN Chengliang ZHANG Jianwu | 2007 | Chinese Journal of Mechanical Engineering2007，20，1： | 12 |
| 9 | Numerical simulation of bubble plumes in overlying water of gas hydrate in the cold seepage active region显示文摘To study the seismic responses produced by gas hydrate bubble plumes in the cold seepage active region, we constructed a plume water body model based on random medium theory and acoustic velocity model of bubble medium. The plume water body model was forward simulated by finite difference. Seismic records of single shot show the scattered waves produced by the plume. The scattered wave energy is strong where the plume exists. Where the scattered wave energy is stronger, the minimum of travel time is always above the plume, which has no relationship with the shot's position. Seismic records of shot gathers were processed by prestack time migration. The migration section shows that the scattered waves produced by plumes can be imaged distinctly with higher accuracy. These researches laid a foundation for further study on the seismic responses produced by plumes and provided a new approach for the identification of gas hydrate. | LI CanPing LIU XueWei GOU LiMin WANG XiangChun YIN JunJie XIE ChengLiang | 2013 | Science China Earth Sciences2013，56，4： | 11 |
| 10 | Nitric oxide alleviates aluminum-induced oxidative damage through regulating the ascorbateglutathione cycle in roots of wheat显示文摘The possible association with nitric oxide(NO) and ascorbate-glutathione(As A-GSH) cycle in regulating aluminum(Al) tolerance of wheat(Triticum aestivum L.) was investigated using two genotypes with different Al resistance. Exposure to Al inhibited root elongation, and triggered lipid peroxidation and oxidation of As A to dehydroascorbate and GSH to glutathione disulfide in wheat roots. Exogenous NO significantly increased endogenous NO levels, and subsequently alleviated Al-induced inhibition of root elongation and oxidation of As A and GSH to maintain the redox molecules in the reduced form in both wheat genotypes. Under Al stress, significantly increased activities and gene transcriptional levels of ascorbate peroxidase, glutathione reductase, and dehydroascorbate reductase,were observed in the root tips of the Al-tolerant genotype Jian-864. Nitric oxide application enhanced the activity and gene transcriptional level of these enzymes in both wheat genotypes. g-Glutamylcysteine synthetase was not significantly Researaffected by Al or NO, but NO treatments increased the activity of glutathione peroxidase and glutathione S-transferase to a greater extent than the Al-treated wheat seedlings. Proline was significantly decreased by Al, while it was not affected by NO.These results clearly suggest that NO protects wheat root against Al-induced oxidative stress, possibly through its regulation of the As A-GSH cycle. | Chengliang Sun Lijuan Liu Yan Yu Wenjing Liu Lingli Lu Chongwei Jin Xianyong Lin | 2015 | Journal of Integrative Plant Biology2015，57，6： | 10 |
| 11 | ACTIVE FRONT STEERING DURING BRAKING PROCESS显示文摘An active front steering(AFS) intervention control during braking for vehicle stability is presented. Based on the investigation of AFS mechanism, a simplified model of steering system is established and integrated with vehicle model. Then the AFS control on vehicle handling dynamics during braking is designed. Due to the difficulties associated with the sideslip angle measurement of vehicle, a state observer is designed to provide real time estimation. Thereafter, the controller with the feedback of both sideslip and yaw angle is implemented. To evaluate the system control, the proposed AFS controlled vehicle has been tested in the Hardware-in-the-loop-simulation (HILS) system and compared with that of conventional vehicle. Results show that AFS can improve vehicle lateral stability effectively without reducing the braking performance. | CHEN Deling CHEN Li YIN Chengliang ZHANG Yong | 2008 | Chinese Journal of Mechanical Engineering2008，21，4： | 9 |
| 12 | Single-phase multiferroics: new materials, phenomena,and physics显示文摘Multiferroics,where multiple ferroic orders coexist and are intimately coupled,promise novel applications in conceptually new devices on one hand,and on the other hand provide fascinating physics that is distinctly different from the physics of high-Tc superconductors and colossal magnetoresistance manganites.In this mini-review;we highlight the recent progress of single-phase multiferroics in the exploration of new materials,efficient roadmaps for functionality enhancement,new phenomena beyond magnetoelectric coupling,and underlying novel physics.In the meantime;a slightly more detailed description is given of several multiferroics with ferrimagnetic orders and double-layered perovskite structure and also of recently emerging 2D multiferroics.Some emergent phenomena such as topological vortex domain structure,non-reciprocal response,and hybrid mechanisms for multiferroicity engineering and magnetoelectric coupling in various types of multiferroics will be briefly reviewed. | Chengliang Lu Menghao Wu Lin Lin Jun-Ming Liu | 2019 | National Science Review2019，6，4： | 9 |
| 13 | A pre-generated matrix-based method for real-time robotic drilling chatter monitoring显示文摘Currently, due to the detrimental effects on surface finish and machining system, chatter has been one crucial factor restricting robotic drilling operations, which improve both quality and efficiency of aviation manufacturing. Based on the matrix notch filter and fast wavelet packet decomposition, this paper presents a novel pre-generated matrix-based real-time chatter monitoring method for robotic drilling. Taking vibration characteristics of robotic drilling into account, the matrix notch filter is designed to eliminate the interference of spindle-related components on the measured vibration signal. Then, the fast wavelet packet decomposition is presented to decompose the filtered signal into several equidistant frequency bands, and the energy of each sub-band is obtained. Finally, the energy entropy which characterizes inhomogeneity of energy distribution is utilized as the feature to recognize chatter on-line, and the effectiveness of the presented algorithm is validated by extensive experimental data. The results show that the proposed algorithm can effectively detect chatter before it is fully developed. Moreover, since both filtering and decomposition of signal are implemented by the pre-generated matrices, calculation for an energy entropy of vibration signal with 512 samples takes only about 0.690 ms. Consequently, the proposed method achieves real-time chatter monitoring for robotic drilling, which is essential for subsequent chatter suppression. | Jianfeng TAO Chengjin QIN Dengyu XIAO Haotian SHI Chengliang LIU | 2019 | Chinese Journal of Aeronautics2019，32，12： | 9 |
| 14 | Recent progress in solid-state electrolytes for alkali-ion batteries显示文摘Solid-state electrolytes have a lot of advantages, including the inhibition of alkali metal dendrite growth,the elimination of liquid electrolyte leakage, the improvement of safety, the enhancement of energy density and power density, and the potential application in flexible electronics. Therefore, solid-state electrolytes have become one of the hottest topics in energy-storage research area. An up-to-date review on solid-state electrolytes is of not only scientific significance but also technological imperative. Here,recent progress in solid-state electrolytes for alkali ion batteries is summarized. Through this comprehensive review and the comparison of different solid-state electrolytes, we hope it can give a clear figure of the state-of-art status and the development trend of the future solid-state electrolytes. | cheng jiang huiqiao li chengliang wang | 2017 | Science Bulletin2017，62，21： | 9 |
| 15 | Twenty-five years of progress in geopolitics research: Efforts from China's geographers显示文摘 | DU Debin DUAN Dezhong LIU Chengliang MA Yahua | 2016 | Journal of Geographical Sciences2016，26，8： | 9 |
| 16 | Expression of hIGF-I in the silk glands of transgenic silkworms and in transformed silkworm cells显示文摘To express human insulin-like growth factor-I (hIGF-I) in transformed Bombyx mori cultured cells and silk glands, the transgenic vector pigA3GFP-hIGF-ie-neo was constructed with a neomycin resistance gene driven by the baculovirus ie-1 promoter, and with the hIGF-I gene under the control of the silkworm sericin promoter Ser-1. The stably transformed BmN cells expressing hIGF-I were selected by using the antibiotic G418 at a final concentration of 700-800 μg/mL after the BmN cells were transfected with the piggyBac vector and the helper plasmid. The specific band of hIGF-I was detected in the transformed cells by Western blot. The expression level of hIGF-I, determined by ELISA, was about 7800 pg in 5×105 cells. Analysis of the chromosomal insertion sites by inverse PCR showed that exogenous DNA could be inserted into the cell genome randomly or at TTAA target sequence specifically for piggyBac element transposition. The transgenic vector pigA3GFP-hIGF-ie-neo was transferred into the eggs using sperm-mediated gene transfer. Finally, two transgenic silkworms were obtained after screening for the neo and gfp genes and verified by PCR and dot hybridization. The expression level of hIGF-I determined by ELISA was about 2440 pg/g of silk gland of the transgenic silkworms of the G1 generation. | ZHAO Yue, LI Xi, CAO GuangLi, XUE RenYu & GONG ChengLiang· Medical College, Soochow University, Suzhou 215123, China | 2009 | Science China(Life Sciences)2009，52，12： | 9 |
| 17 | Graphitic carbon nitride/biochar composite synthesized by a facile ball-milling method for the adsorption and photocatalytic degradation of enrofloxacin显示文摘In order to enhance the removal performance of graphitic carbon nitride(g-C_(3)N_(4)) on organic pollutant, a simultaneous process of adsorption and photocatalysis was achieved via the compounding of biochar and g-C_(3)N_(4). In this study, g-C_(3)N_(4) was obtained by a condensation reaction of melamine at 550 °C. Then the g-C_(3)N_(4)/biochar composites were synthesized by ball milling biochar and g-C_(3)N_(4) together, which was considered as a simple, economical, and green strategy. The characterization of resulting g-C_(3)N_(4)/biochar suggested that biochar and g-C_(3)N_(4) achieved effective linkage. The adsorption and photocatalytic performance of the composites were evaluated with enrofloxacin(EFA) as a model pollutant. The result showed that all the g-C_(3)N_(4)/biochar composites displayed higher adsorption and photocatalytic performance to EFA than that of pure g-C_(3)N_(4). The 50% g-C_(3)N_(4)/biochar performed best and removed 45.2% and 81.1% of EFA(10 mg/L) under darkness and light with a dosage of 1 mg/mL, while g-C_(3)N_(4) were 19.0% and 27.3%, respectively. Besides, 50% g-C_(3)N_(4)/biochar showed the highest total organic carbon(TOC) removal efficiency(65.9%). Radical trapping experiments suggested that superoxide radical( ·O_(2)^(-)) and hole(h~+) were the main active species in the photocatalytic process. After 4 cycles, the composite still exhibited activity for catalytic removal of EFA. | Yao Xiao Honghong Lyu Chengliang Yang Beibei Zhao Lan Wang Jingchun Tang | 2021 | Journal of Environmental Sciences2021，33，5： | 8 |
| 18 | Realization and Analysis of Good Fuel Economy and Kinetic Performance of a Low-cost Hybrid Electric Vehicle显示文摘By using high-power and high-efficiency propulsion systems,current hybrid electric vehicles(HEVs) in market can achieve excellent fuel economy and kinetic performance.However,it is the cost of current HEVs that hinders HEVs coming into widespread use.A novel hybrid electric propulsion system is designed to balance HEV cost and performance for developing markets.A battery/supercapacitor-based hybrid energy storage system(HESS) is used to improve energy conversion efficiency and reduce battery size and cost.An all-in-one-controller(AIOC) which integrates engine electronic control unit(ECU),motor ECU,and HESS management system is developed to save materials and energy,and reduce the influence of distribution parameters on circuit.As for the powertrain configuration,four schemes are presented:belt-driven starter generator(BSG) scheme,four-wheel drive HEV scheme,full HEV scheme,and ranger-extender electric vehicle(EV) scheme.Component selection and parameter matching for the propulsion system are performed,and an energy management strategy is developed based on powertrain configuration and selected components.Forward-facing simulation models are built,comprehending the control strategy based on the optimal engine torque for the low-cost hybrid electric propulsion system.Co-simulation of AVL CRUISE and Matlab/Simulink is presented and the best scheme is selected.The simulation results indicate that,for the best design,fuel consumption in urban driving condition is 4.11 L/(100 km) and 0-50 km/h accelerating time is 10.95 s.The proposed research can realize low-cost concept for HEV while achieving satisfactory fuel economy and kinetic performance,and help to improve commercialization of HEVs. | WANG Lei ZHANG Jianlong YIN Chengliang ZHANG Yong WU Zhiwei | 2011 | Chinese Journal of Mechanical Engineering2011，24，5： | 7 |
| 19 | DEVELOPMENT OF THE ENERGY MANAGEMENT STRATEGY FOR PARALLEL HYBRID ELECTRIC URBAN BUSES显示文摘A novel parallel hybrid electrical urban bus (PHEUB) configuration consisting of an extra one-way clutch and an automatic mechanical transmission (AMT) is taken as the study subject. An energy management strategy combining a logic threshold approach and an instantaneous optimization algorithm is proposed for the investigated PHEUB. The objective of the energy management strategy is to achieve acceptable vehicle performance and drivability requirements while simultaneously maximizing the engine fuel consumption and maintaining the battery state of charge in its operation range at all times. Under the environment of Matlab/Simulink, a computer simulation model for the PHEUB is constructed by using the model building method combining theoretical analysis and bench test data. Simulation and experiment results for China Typical Bus Driving Schedule at Urban District (CTBDS_UD) are obtained, and the results indicate that the proposed control strategy not only controls the hybrid system efficiently but also improves the fuel economy significantly. | HUANG Yuanjun YIN Chengliang ZHANG Jianwu | 2008 | Chinese Journal of Mechanical Engineering2008，21，4： | 7 |
| 20 | Study on the structure characterization and moisturizing effect of Tremella polysaccharide fermented from GCMCC5.39显示文摘The structure and moisture retention of Tremella polysaccharide fermented from GCMCC5.39(FTP)were evaluated.After UV,infrared spectrum analysis,HPAEC-PAD,HPSEC and 1 D NMR analysis,the composition of the purifi ed FTP was determined.Purifi ed components of fermented Tremella polysaccharide(FTPS)was made of galactose,mannose,glucose,galactosmine,glucosamine,and contain a large amount of hydroxyl,carbonyl and amino groups.FTPS wasα-neutral pyranose without uronic acid.FTPS-1 and FTPS-2 were obtained after purifi cation by DEAE-Sepharose Fast Flow Column.The molecular weights of FTPS-1 and FTPS-2 were 25722 and 177263 Da.FTPS-2 had a better ability to prevent moisture loss,and the optimal moisture retention period was 0–4 h.FTPS-2 could signifi cantly increase the moisture content of the skin epidermis and showed a dose-concentration relationship.The effect of FTPS-2 on the expression of different moisturizing genes was evaluated in a human skin keratinocyte model.The results showed that FTPS-2 has no cytotoxicity,and could signifi cantly promote AQP3,TGM1,CASP14,HYAL2,FLG gene expression level in HaCaT cells.It has the most signifi cant infl uence at HYAL2 protein expression on 50μg/mL. | Meng Yang Zilong Zhang Yan He Chengliang Li Jinmei Wang Xia Ma | 2021 | Food Science and Human Wellness2021，10，4： | 6 |
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