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| 1 | 醌氧化还原酶1抑制剂双香豆素促进HBV X蛋白降解进而抑制cccDNA转录的机制研究显示文摘【据Journal of Hepatology2021年3月报道】题:醌氧化还原酶1抑制剂双香豆素促进HBV X蛋白降解进而抑制ccc DNA转录的机制研究(作者Cheng ST等)HBV ccc DNA在肝细胞核内持续稳定的存在,被认为是HBV感染慢性化、抗病毒治疗无法彻底清除以及停药后肝炎复发的最主要原因。HBV X蛋白(HBx)对HBV ccc DNA的转录过程发挥关键作用;促进HBx降解,则可能抑制ccc DNA转录。因此,开发靶向HBx的小分子化合物是达到'ccc DNA沉默清除'这一重要目标的可能途径。 | 陈娟 黄爱龙 CHENG ST HU JL REN JH | 2021 | 临床肝胆病杂志2021，37，4： | 12 |
| 2 | TOTAL SYNTHESIS OF CLAUSENAMIDE显示文摘TOTAL SYNTHESIS OF CLAUSENAMIDETOTALSYNTHESISOFCLAUSENAMIDE￥ErChangRAO;HaoHONG;JiaChongCHENG;GuangZhongYANG;HanSenLIN;andLian... | Er Chang RAO Hao HONG Jia Chong CHENG Guang Zhong YANG Han Sen LIN andLiang HUANG(Institute of Mareia Medica. Chinese Academy of Medical Sciences1 Xian Nong Tan St .Beijing 100050) | 1994 | Chinese Chemical Letters1994，5，4： | 4 |
| 3 | Comprehensive evaluation of mechanism of 'chimney effect' using principles of magnetism, geochemistry and mineralogy显示文摘Study of forming mechanism of 'chimney-effect' (CE) has important significance for basic theory and applications of non-seismic geophysical and geochemical methods locating oil/gas reservoirs. The theoretical basis of comprehensive evaluation of mechanism of CE using principles of magnetism, geochemistry and mineralogy has been reviewed, with the problems to be solved: (ⅰ) study for the relationship between process of oil/gas migration and geochemical field; (ⅱ) analysis of genesis of magnetic, geochemical and mineralogical anomaly; (ⅲ) interpretation of surface soil magnetism and geochemical anomaly combined with seismic data. | LIU Qingsheng 1, CHENG Tongjin 2 and LIU Shugen 3 1. Department of Applied Geophysics, China University of Geosciences, Wuhan 430074, China 2. Center of Petroleum Geochemistry, China National Star Petroleum Corporation, Hefei 230022, China 3. The St | 1998 | Chinese Science Bulletin1998，43，9： | 3 |
| 4 | Light induced retinal damage involves tyrosine 33 phosphorylation, mitochondrial and nuclear translocation of WW domain-containing oxidore-ductase in vivo 显示文摘 | Chen ST Chuang Jf Cheng CL | 2005 | Neuroscience2005，130，2： | 1 |
| 5 | Systemic high-sensitivity C-reactive protein levels in normal-tension glaucoma and primary open-angle glaucoma显示文摘 | Su WW Ho WJ Cheng ST | 2007 | J Glaucoma2007，16，3： | 1 |
| 6 | Efficacy of dilute betadine solution imigation in the prevention of postoperative infection of spinal surgery显示文摘 | Cheng MT Chang MC Wang ST | 2005 | spine2005，，： | 1 |
| 7 | Breast cancer risk associated with genotype polymorphism of the catechol estrogen metabolizing genes : a multigenic study on cancer susceptibility 显示文摘 | Cheng TC Chen ST Huang CS | 2005 | Int J Cancer2005，113，3： | 1 |
| 8 | Serum CA125 in preoperative patients at high risk for endometriosis显示文摘 | Cheng YM Wang ST Chou CY | 2002 | Obstet Gynecol2002，99，3： | 1 |
| 9 | Factorial structure of a short version of the Center for Epidemiologic Studies Depression Scale显示文摘 | Cheng ST Chan A Fung HH | 2006 | Int J Geriatr Psychiatry2006，21，4： | 1 |
| 10 | Evolution of microbiological trends and treatment outcomes in peritoneal dialysis-related peritonitis 显示文摘 | Huang ST Chuang YW Cheng CH | 2011 | Clin Nephrol2011，75，5： | 1 |
| 11 | The Center for Epidemiologic Studies Depression Scale in older Chinese:thresholds for long and short forms显示文摘 | Cheng ST Chan A | 2005 | hat J Geriatr Psychiatry2005，20，5： | 1 |
| 12 | Leisure activities alle-viate depressive symptoms in nursing home residents withvery mild or mild dementia显示文摘 | Cheng ST Chow PK Edwin CS et aZ | 2012 | Am J Geriat Psych2012，20，10： | 1 |
| 13 | A brief version of the Geriatric Depression Scale for the Chinese显示文摘 | Cheng ST Chan A | 2004 | Psychol Assess2004，16，2： | 1 |
| 14 | Neuropsychiatric symptom clusters of Alzheimer disease in Hong Kong Chinese:correlates with caregiver burden and depression显示文摘 | Cheng ST Lam LC Kwok T | | 0，，10： | 1 |
| 15 | Magmatic hydrothermal superlarge metallogenic systems-a case study of the Nannihu ore field 显示文摘 | Wang CM Cheng QM Zhang ST | 2008 | Journal of China University of Geoseiences2008，19，： | 1 |
| 16 | Facilitation d fiberoptic nasotracheal intubation by simultaneous direct laryngoscopy in anesthetized patient 显示文摘 | Cheng CH Wong CS Ho ST | 2001 | Acta Anaesthesiol Sin2001，39，2： | 1 |
| 17 | The information content of panoramic images I:The rotational errors and the similarity of views in rectangular experimental arenas显示文摘 | Stürzl W Cheung A Cheng K Zeil J | | 0，，： | 1 |
| 18 | Mental and physical activities de- lay cognitive decline in older persons with dementia显示文摘 | Cheng ST Chow PK Song YQ | 2014 | Am J Geriatr Psychiatry2014，22，1： | 1 |
| 19 | Glaucoma is associated with peripheral vascular endothelial dysfunction显示文摘 | Su WW Cheng ST Ho WJ | 2008 | Ophthalmology2008，115，7： | 1 |
| 20 | Self-efficacy Is Associated With Less Burden and More Gains From Behavioral Problems of Alzjeimer’s Disease in Hong Kong Chinese Care-givers显示文摘 | Cheng ST Lam LCW Kwok T | 2012 | Gerontologist2012，53，1： | 1 |
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