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| 1 | Multicenter Evaluation of the Molecular Line Probe Assay for Multidrug Resistant Mycobacterium Tuberculosis Detection in China显示文摘In order to evaluate the performance of a molecular Hain line probe assay(Hain LPA)for rapid detection of rifampicin and isoniazid resistance of Mycobacterium tuberculosis in China。 | LI Qiang DONG Hai Yan PANG Yu XIA Hui OU Xi Chao ZHANG Zhi Ying LI Jun Chen ZHANG Jian Kang HUAN Shi Tong CHIN Daniel P KAM Kai Man ZHAO Yan Lin | 2015 | Biomedical and Environmental Sciences2015,28,6: | 13 |
| 2 | Operative complications and economic outcomes of cholecystectomy for acute cholecystitis显示文摘BACKGROUND Recent management of acute cholecystitis favors same admission(SA)or emergent cholecystectomy based on overall shorter hospital stay and therefore cost savings.We adopted the practice of SA cholecystectomy for the treatment of acute cholecystitis at our tertiary care center and wanted to evaluate the economic benefit of this practice.We hypothesized that the existence of complications,particularly among patients with a higher degree of disease severity,during SA cholecystectomy could negate the cost savings.AIM To compare complication rates and hospital costs between SA vs delayed cholecystectomy among patients admitted emergently for acute cholecystitis.METHODS Under an IRB-approved protocol,complications and charges for were obtained for SA,later after conservative management(Delayed),or elective cholecystectomies over an 8.5-year period.Patients were identified using the acute care surgery registry and billing database.Data was retrieved via EMR,operative logs,and Revenue Cycle Operations.The severity of acute cholecystitis was graded according to the Tokyo Guidelines.TG18 categorizes acute cholecystitis by Grades 1,2,and 3 representing mild,moderate,and severe,respectively.Comparisons were analyzed withχ2,Fisher’s exact test,ANOVA,ttests,and logistic regression;significance was set at P<0.05.RESULTS Four hundred eighty-six(87.7%)underwent a SA while 68 patients(12.3%)received Delayed cholecystectomy.Complication rates were increased after SA compared to Delayed cholecystectomy(18.5%vs 4.4%,P=0.004).The complication rates of patients undergoing delayed cholecystectomy was similar to the rate for elective cholecystectomy(7.4%,P=0.35).Mortality rates were 0.6%vs 0%for SA vs Delayed.Patients with moderate disease(Tokyo 2)suffered more complications among SA while none who were delayed experienced a complication(16.1%vs 0.0%,P<0.001).Total hospital charges for SA cholecystectomy were increased compared to a Delayed approach($44500±$59000 vs$35300±$16700,P=0.019).The relative risk of developing a complication was 4.2x[95%confidence interval(CI):1.4-12.9]in the SA vs Delayed groups.Among eight patients(95%CI:5.0-12.3)with acute cholecystitis undergoing SA cholecystectomy,one patient will suffer a complication.CONCLUSION Patients with Tokyo Grade 2 acute cholecystitis had more complications and increased hospital charges when undergoing SA cholecystectomy.This data supports a selective approach to SA cholecystectomy for acute cholecystitis. | Christopher P Rice Krishnamurthy B Vaishnavi Celia Chao Daniel Jupiter August B Schaeffer Whitney R Jenson Lance W Griffin William J Mileski | 2019 | World Journal of Gastroenterology2019,25,48: | 8 |
| 3 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019,35,6: | 3 |
| 4 | Analysis of assembly through product configuration 显示文摘 | Chao P Y Chen T T | 2001 | Computer in Industry2001,,44: | 2 |
| 5 | Fluorescence and SEM correlative microscopy for nanomanipulation of subcellular structures显示文摘Nanomanipulation under scanning electron microscopy(SEM)enables direct interactions of a tool with a sample.We recently developed a nanomanipulation technique for the extraction and identification of DNA contained within sub-nuclear locations of a single cell nucleus.In nanomanipulation of sub-cellular structures,a key step is to identify targets of interest through correlating fluorescence and SEM images.The DNA extraction task must be conducted with low accelerating voltages resulting in low imaging resolutions.This is imposed by the necessity of preserving the biochemical integrity of the sample.Such poor imaging conditions make the identification of nanometer-sized fiducial marks difficult.This paper presents an affine scale-invariant feature transform(ASIFT)based method for correlating SEM images and fluorescence microscopy images.The performance of the image correlation approach under different noise levels and imaging magnifications was quantitatively evaluated.The optimal mean absolute error(MAE)of correlation results is 68634 nm under standard conditions.Compared with manual correlation by skilled operators,the automated correlation approach demonstrates a speed that is higher by an order of magnitude.With the SEM-fluorescence image correlation approach,targeted DNA was successfully extracted via nanomanipulation under SEM conditions. | Zheng Gong Brandon K Chen Jun Liu Chao Zhou Dave Anchel Xiao Li Ji Ge David P Bazett-Jones Yu Sun | 2014 | Light(Science & Applications)2014,3,1: | 2 |
| 6 | The importance of an indigenous tree to southern African communities with specific relevance to its domestication and commercialization: a case of the marula tree显示文摘Local communities in southern Africa derive many benefits from marula [Sclerocarya birrea(A.Rich.) Hochst.subsp.caffra(Sond.) Kokwaro].These include the contribution of this species towards health,nutrition,food security and conservation by sharing local skills and knowledge related to it.Marula fruits can be eaten fresh,squeezed to make juice,brewed in traditional beer or used to make jam and jelly.The kernels are also edible and can be pressed to extract oil for cooking and cosmetics,i.e.,for skin and hair application.The bark,roots,seeds and leaves are exploited for traditional medicinal purposes.Marula has acquired significant commercial value since its fruits and other products have entered local,regional and international trade in southern Africa.To diver-sify fruit production and satisfy the increasing demands for this resource,several domestication initiatives have been carried out at regional and international levels.The accumulated knowledge and skills relevant to the establishment and commercialization of marula therefore provide an effective guide in areas where marula remains undomesticated or underutilized.We discuss the great importance of marula in southern Africa to reveal its great potential to regions where it remains unexploited. | Neo C MOKGOLODI DING You-fang Moffat P SETSHOGO MA Chao LIU Yu-jun | 2011 | Forestry Studies in China2011,13,1: | 2 |
| 7 | Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis显示文摘 | Mary Eapen Vanderson Rocha Guillermo Sanz Andromachi Scaradavou Mei-Jie Zhang William Arcese Anne Sirvent Richard E Champlin Nelson Chao Adrian P Gee Luis Isola Mary J Laughlin David I Marks Samir Nabhan Annalisa Ruggeri Robert Soiffer Mary M Horowitz Eli | 2010 | Lancet Oncology2010,,7: | 2 |
| 8 | Non-planar dynamic modeling for the optical disk drive spindles equipped with an automatic balancer显示文摘 | Chao P C Huang Y D Sung C K | 2003 | Mechanism and Machine Theory2003,38,: | 1 |
| 9 | Use of a long-acting gonadotropin-releasing hormone agonist for treatment of steroid cell tumors ofthe ovary显示文摘 | Wang P H Chao H T Lee W L | 1998 | Fertil Steri1998,69,2: | 1 |
| 10 | Effects of fertilization promoting peptide,adenosine,and pentoxifylline on thawed human sperm显示文摘 | Huang P T Chen S U Chao K H | 2003 | Arch Androl2003,49,2: | 1 |
| 11 | Neuroprotective effect of osthole against oxygen andglucose deprivation in rat cortical neurons:involvementof mitogen-activated protein kinase pathway显示文摘 | Chen T Liu W Chao X Qu Y Zhang L Luo P | 2011 | Neuro-science2011,183,: | 1 |
| 12 | A previously unknown zinc finger protein DST regulates drought and salt tolerance in rice via stomatal aperture control 显示文摘 | Huang X Y Chao D Y Gao ] P | 2009 | Genes Development2009,23,15: | 1 |
| 13 | Tourism, jobs, capital accumulation and the economy : A dynamic analysis 显示文摘 | Chao C Hazari B Laffargue P ( 2005 ) | 2005 | Department of Economics2005,,: | 1 |
| 14 | Ultrasound assessment of cervical length in pregnancy 显示文摘 | Chao A S Chao A Hsieh P C | 2008 | Taiwan J Obstet Gynecol2008,47,3: | 1 |
| 15 | Production of bacterial cellulose by Acetobacter xylinum with an air-lift reactor显示文摘 | Chao Y P Sugano Y Kouda T | 1991 | Biotechnology Techniques1991,11,: | 1 |
| 16 | Steroid cell tumors of the ovary : clinical, ultrasonic, and MRI diagnosis:a case report 显示文摘 | Wang P H Chao H T Lee R C | 1998 | Eur J Radiol1998,26,3: | 1 |
| 17 | Detection of defects on selected apple cultivars using hyperspectral and multispectral image analysis显示文摘 | Mehl P M Chao K Kim M | 2002 | Applied Engineering in Agriculture2002,18,2: | 1 |
| 18 | Water-to-air mass transfer of VOCs: Lahoratory-scale air sparging system显示文摘 | Chao K P Ong S K Protopapas A | 1998 | Journal of Envi?ronmental Engineering1998,124,11: | 1 |
| 19 | Pathway analysis, engineering, and physiological considerations for redirecting central metabolism 显示文摘 | Liao J C Hou S Y Chao Y P | 1996 | Biotechnol Bioeng1996,52,1: | 1 |
| 20 | Knowing when to grow:signals regulating bud dormancy显示文摘 | HORVATH D P ANDERSON J V CHAO W S FOLEY M E | 2003 | Trends in Plant Science2003,8,: | 1 |