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| 1 | A deep learning-enabled portable imaging flow cytometer for cost-effective, highthroughput, and label-free analysis of natural water samples显示文摘We report a deep learning-enabled field-portable and cost-effective imaging flow cytometer that automatically captures phase-contrast color images of the contents of a continuously flowing water sample at a throughput of 100 mL/h.The device is based on partially coherent lens-free holographic microscopy and acquires the diffraction patterns of flowing micro-objects inside a microfluidic channel.These holographic diffraction patterns are reconstructed in real time using a deep learning-based phase-recovery and image-reconstruction method to produce a color image of each micro-object without the use of external labeling.Motion blur is eliminated by simultaneously illuminating the sample with red,green,and blue light-emitting diodes that are pulsed.Operated by a laptop computer,this portable device measures 15.5 cm×15 cm×12.5 cm,weighs 1 kg,and compared to standard imaging flow cytometers,it provides extreme reductions of cost,size and weight while also providing a high volumetric throughput over a large object size range.We demonstrated the capabilities of this device by measuring ocean samples at the Los Angeles coastline and obtaining images of its micro-and nanoplankton composition.Furthermore,we measured the concentration of a potentially toxic alga(Pseudo-nitzschia)in six public beaches in Los Angeles and achieved good agreement with measurements conducted by the California Department of Public Health.The cost-effectiveness,compactness,and simplicity of this computational platform might lead to the creation of a network of imaging flow cytometers for largescale and continuous monitoring of the ocean microbiome,including its plankton composition. | Zoltán Gӧrӧcs Miu Tamamitsu Vittorio Bianco Patrick Wolf Shounak Roy Koyoshi Shindo Kyrollos Yanny Yichen Wu Hatice Ceylan Koydemir Yair Rivenson Aydogan Ozcan | 2018 | Light(Science & Applications)2018，7，1： | 14 |
| 2 | Comparison of FCM,PCA and WT techniques for classification ECG arrhythmias using artificial neural network显示文摘 | Ceylan R Ozbay Y | 2007 | Expert Systems with Applications2007，33，2： | 1 |
| 3 | A fuzzy clustering neural network architecture for classification of ECG arrhythmias显示文摘 | Ozbay Y Ceylan R Karlik B | 2006 | Computers in Biology and Medicine2006，36，4： | 1 |
| 4 | Integration of type 2 fuzzy clustering and wavelet transform in a neural network based ECG classifier显示文摘 | ZBAY Y CEYLAN R KARLIK B | 2011 | Expert Systems with Applications2011，38，1： | 1 |
| 5 | Comparison of FCM, PCA and WT tech- niques for classification ECG arrhythmias using artificial neural net- work显示文摘 | R Ceylan Y Ozbay | 2007 | Expert Systems with Applications2007，33，2： | 1 |
| 6 | Neural networks modeling of stress growth in asphalt overlays due to loadand thermal effects during reflection cracking 显示文摘 | Ceylan H Gopalakrishnan K Lytton R L | 2011 | Journal of Materials in Civil Engineering2011，23，3： | 1 |
| 7 | Trace elements and oxidative stress in chronic obstructive pulmonary disease显示文摘 | Isik B Isik R S Ceylan A | 2005 | Saudi Med J2005，26，12： | 1 |
| 8 | Oxidative stress in smokers and nonsmokers 显示文摘 | Isik B Ceylan A Isik R | 2007 | Inhal Toxicol2007，19，： | 1 |
| 9 | A novel approach for classification of ECG arrhythmias:Type-2 fuzzy clustering neural network显示文摘 | Ceylan R Ozbay Y Karlik B | 2009 | Expert Systems with Applications2009，36，32： | 1 |
| 10 | Neural networks modeling of stress growth in asphalt overlays due to load and thermal effects during reflection cracking 显示文摘 | Ceylan H Gopalakrishnan K Lytton R L | 2011 | Journal of Materials in Civil Engineering2011，23，3： | 1 |
| 11 | A novel approach for classification of ECG arrhythmias: Type-2 fuzzy clustering neural network显示文摘 | CEYLAN R OZBAY Y KARLIK B | 2008 | Expert Systems with Applications2008，36，3： | 1 |
| 12 | Recent progress on conventional and non-conventional electrospinning processes显示文摘 | KHAN W S ASMATULU R CEYLAN M | 2013 | Fibers and Polymers2013，14，8： | 1 |
| 13 | Effect of indapamide on urinary calcium excretion in patients with and without urinary stone disease显示文摘 | Ceylan K Topal C Erkoc R | 2005 | Ann Pharmacother2005，39，6： | 1 |
| 14 | Imaging findings of vascular lesions in the head and neck 显示文摘 | Gtineyli S Ceylan N Sava R | 2014 | Diagn Interv Radiol2014，19，3： | 1 |
| 15 | Oxidative stress in smokers and non-smokers显示文摘 | CEYLAN A ISIK R | 2007 | Inhal Toxicol2007，19，9： | 1 |
| 16 | A fuzzy clustering neura/ net- work architecture for classification of ECG arrhythmias 显示文摘 | Ozbay Y Ceylan R Karlik B | 2006 | Computers in Biology and Medicine2006，36，4： | 1 |
| 17 | Neural networks modeling of stress growth in as- phalt overlays due to load and thermal effects during reflection cracking显示文摘 | CEYLAN H GOPALAKRISHNAN K LYTTON R L | 2010 | Journal of Materials in Civil Engineering2010，23，3： | 1 |
| 18 | Work Alienation as a Mediator of the Relationship between Organizational Injustice and Organizational Commitment : Implications for Healthcare Professionals 显示文摘 | Sulu S Ceylan A & Kaynak R | 2010 | Interna- tional Journal of Business and Management2010，5，： | 1 |
| 19 | 显示文摘 | Asraatulu R Ceylan M Nuraje N | 2011 | Langmuir2011，27，2： | 1 |
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