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| 1 | Alcoholism: A systemic proinflammatory condition显示文摘Excessive ethanol consumption affects virtually any organ,both by indirect and direct mechanisms.Considerable research in the last two decades has widened the knowledge about the paramount importance of proinflammatory cytokines and oxidative damage in the pathogenesis of many of the systemic manifestations of alcoholism.These cytokines derive primarily from activated Kupffer cells exposed to Gram-negative intestinal bacteria,which reach the liver in supra-physiological amounts due to ethanol-mediated increased gut permeability.Reactive oxygen species(ROS)that enhance the inflammatory response are generated both by activation of Kupffer cells and by the direct metabolic effects of ethanol.The effects of this increased cytokine secretion and ROS generation lie far beyond liver damage.In addition to the classic consequences of endotoxemia associated with liver cirrhosis that weredescribed several decades ago,important research in the last ten years has shown that cytokines may also induce damage in remote organs such as brain,bone,muscle,heart,lung,gonads,peripheral nerve,and pancreas.These effects are even seen in alcoholics without significant liver disease.Therefore,alcoholism can be viewed as an inflammatory condition,a concept which opens the possibility of using new therapeutic weapons to treat some of the complications of this devastating and frequent disease.In this review we examine some of the most outstanding consequences of the altered cytokine regulation that occurs in alcoholics in organs other than the liver. | Emilio González-Reimers Francisco Santolaria-Fernández María Candelaria Martín-González Camino María Fernández-Rodríguez Geraldine Quintero-Platt | 2014 | World Journal of Gastroenterology2014，20，40： | 12 |
| 2 | On the Restricted Arc-connectivity of s-geodetic Digraphs显示文摘为强烈连接的两个字母并成的一个单音 D 限制弧连接位鈥 ? D ) 在所有弧切割 S 上被定义为弧切割的最小的集的势令人满意那 D - S 有重要强壮的部件 D 1 以便 D-V (D 1 ) 包含一条弧。让 S 是 D 的顶点的一个子集。我们与 u 鈭 ? S 和 v 由蠅 +(S) 表示弧 uv 的集合吗?S,并且由蠅 ?(S) 有 u 的弧 uv 的集合?S 和 v 鈭 ? S。两个字母并成的一个单音 D =(V,一) 被说是位鈥 ? 最佳如果位鈥 ? D )= 尉鈥 ? D ) ,在此尉鈥 ? D ) D 的最小的弧度被定义为尉(D )= min { 尉鈥 ? xy ) :xy 鈭 ? A } ,并且尉鈥 ? xy )= min {| 蠅 +({ x, y })| , | 蠅 ?({ x, y })| , | 蠅 +(x) 鈭 ? 蠅 ?(y)| , | 蠅 -(x) 鈭 ?(y)|} 。为是位鈥 ? 的 s 测地学的强烈连接的两个字母并成的一个单音 D 在这糊一个足够的条件最佳以它的直径被给。而且,我们看到 s 测地学的两个字母并成的一个单音的重申 h 的线两个字母并成的一个单音 L h (D) 是为某些重复 h 最佳的位鈥 ? 。关键词限制了弧连接-弧切割-直径-s测地学的两个字母并成的一个单音-线两个字母并成的一个单音 k ]先生( 2000 )题目分类 05C35 -教育部和科学,西班牙,和欧洲地区性的发展资金( ERDF )在工程 MTM2008-06620-C03-02 下面支持的 05C40 ,并且由在工程 P06-FQM-01649 下面的 Andalusian | Camino BALBUENA Pedro GARCíA-VZQUEZ | 2010 | Acta Mathematica Sinica,English Series2010，26，10： | 4 |
| 3 | Right Living Donor Liver Transplantation: An Option for Adult Patients: Single Institution Experience With 74 Patients显示文摘 | Massimo Malagó Giuliano Testa Andrea Frilling Silvio Nadalin Camino Valentin-Gamazo Andreas Paul Hauke Lang Ulrich Treichel Vito Cicinnati Guido Gerken Christoph Erich Broelsch | 2003 | Annals of Surgery2003，，6： | 2 |
| 4 | Fire retardant halogen - antimony - clay synergism in polypropylene layered ailicate nanocomposites 显示文摘 | Zanetti M Camino G Canavese D | 2002 | Chemical Material2002，14，： | 1 |
| 5 | Study of the Mechanism of Intumescence in Fire Retardant Polymers: Mechanism of Action in Polypropylene-Ammonium Polyphosphate- Pentaerythritol Mixture显示文摘 | Camino G Costa L Trossarelli L | 1984 | Polymer Degradation and Stability1984，，7： | 1 |
| 6 | Mechanism of condensed phase action in fire retardant bismuth compound-chloroparaflin-poly- propylene mixtures: Part I -The role ofbismuth trichloride and oxy- chloride 显示文摘 | Costa L Camino G Cortemiglia M P L | 1986 | Polym Degrad Stab1986，14，： | 1 |
| 7 | Effect of hydroxides and hydroxycarbonate strcture on fire retardant effectiveness and mechanical properties in ethylene-vinyl acetate copolymer 显示文摘 | Camino G Maffezzoli A Braglia M De Lazzaro M Zammarano M | 2001 | Polymer Degradation and Stability2001，，74： | 1 |
| 8 | Bordetella bronchiseptica pneumonia in patients with HIV显示文摘 | VALENCIA M E ENRIQUEZ A CAMINO N | 2004 | Enferm Infecc Microbiol Clin2004，22，： | 1 |
| 9 | Overview of Fire Retardant Meehanisms显示文摘 | Camino G Cost L Luda Di Cortemiglia M P | 1991 | Polymer Degradation and Stability1991，33，2： | 1 |
| 10 | On the syn- thesis of a-zirconium phosphate 显示文摘 | CAMINO T SERGEI A K JOSE R G | 2000 | Chem Mater2000，12，6： | 1 |
| 11 | Bordetellabronchiseptica pneumonia in patients with HIV显示文摘 | Valencia ME Enriquez A Camino N | 2004 | EnfermInfecc Microbiol Clin2004，22，8： | 1 |
| 12 | Youth leadership:Linking research and program theory to exemplary practice显示文摘 | Zeldin S Camino L | | 0，，： | 1 |
| 13 | Deposition and tribological behaviour of sputtered carbon hard coatings显示文摘 | Yang S Camino D Jones A H S | | 0，，2： | 1 |
| 14 | Oncogenie potential of EAGK(+) channels 显示文摘 | Pardo LA del Camino D S6nchez A | 1999 | EMBO J1999，18，20： | 1 |
| 15 | Mechanistic Study of Thermal Behaviour and Combustion Performance of Carbon Fibre-epoxy Resin Composites Fire Retarded with a Phosphorus-based Curing System显示文摘 | Sergei V Levchik Giovanni Camino Maria Paola Luda | 1996 | Polymer Degradation and Stability1996，54，3： | 1 |
| 16 | Ghrelin, a novel placental, derived hormone 显示文摘 | GUALILLO O CAMINOS J BLANCO M et at | 2001 | Endocrinology2001，142，2： | 1 |
| 17 | Thermal Degradtion of Pentaerythritol Diphosphate Model Compoud for Fire Retardant Instumescent System 显示文摘 | Camino G Martinasso G Costa L | 1990 | Polymer Degradtion and Stability1990，27，： | 1 |
| 18 | Thermal degradation and fire retardancy of antimony and bismuth trihalides-melamine complexes 显示文摘 | L Costa G Camino G Bertelli | 1991 | Polymer Degradation and Stability1991，34，13： | 1 |
| 19 | High performance sputtered carbon coatings for wear resistant applications显示文摘 | Camino D Jones A H S Mercs D | 1999 | Vacuum1999，52，： | 1 |
| 20 | Supplementation of oils with oleanolic acid from the olive leaf (Olea europaea)显示文摘 | GUINDA A ALBI T CAMINO M C P | 2004 | European Journal of Lipid Science and Technology2004，106，： | 1 |
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