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| 1 | Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4显示文摘最近的尖铁 glycoprotein (S) 鉴别中东呼吸症候群 coronavirus (MERS-CoV ) 指向细胞的受体, dipeptidyl peptidase 4 (DPP4 ) 。顺序比较和当模特儿的分析在病毒的尖铁上揭示了一个通常认为的受体绑定领域(RBD ) ,它调停这个相互作用。我们报导 3.0 Å MERS-CoV RBD 的决定水晶结构跳了到人的 DPP4 的细胞外的领域。我们的结果证明 MERS-CoV RBD 由一个核心和受体绑定子域组成。受体绑定子域与 DPP4 β 交往;推进器然而并非它的内在的 hydrolase 领域。MERS-CoV RBD 和相关 SARS-CoV RBD 分享他们的核心子域的结构的类似的高度,但是在受体绑定子域是尤其是分叉的。Mutagenesis 研究在为到 DPP4 和入口的病毒的绑定是批评的进目标房间的受体绑定子域识别了几关键残余。在在 MERS-CoV RBD 和 DPP4 之间的接口的原子细节提供病毒和受体相互作用的结构的理解,它能对 MERS-CoV 感染指导治疗学和疫苗的开发。 | Nianshuang Wang Xuanling Shi Liwei Jiang Senyan Zhang Dongli Wang Pei Tong Dongxing Guo Lili Fu Ye Cui Xi Liu Kelly C Arledge Ying-Hua Chen Linqi Zhang Xinquan Wang | 2013 | Cell Research2013,23,8: | 26 |
| 2 | Unusual life-threatening Rosai-Dorfman disease of the trachea. role of NF-kappa B显示文摘 | Zhou, LF Chen, LA Zhu, QA Wang, C Xu, H Cui, XF Jiang, LF He, Ski Huang, M Yin, KS | 2010 | 南京医科大学学报(自然科学版)2010,30,11: | 21 |
| 3 | Potent antitumor efficacy of an E1B 55kDa-deficient adenovirus carrying murine endostatin in hepatocellular carcinoma显示文摘 | Li G Sham J Yang J Su C Xue H Chua D Sun L Zhang Q Cui Z Wu M Qian Q | 2005 | 第二军医大学学报2005,26,11: | 9 |
| 4 | Environmental and Psycho-social Factors Related to Prostate Cancer Risk in the Chinese Population:a Case-control Study显示文摘Objective To study the risk environmental and psycho-social factors associated to prostate cancer(PCa) in Chinese population. Methods 250 PCa patients and 500 controls were enrolled in this case-control study. Information was collected and logistic regression analysis was used to estimate the odds ratios(OR) and 95% confidence intervals(95% CI) for relationship between lifestyle, eating habits and psycho-social factors with PCa risk. Results Green vegetables and green tea were associated with a decreased risk of PCa(OR=0.39, 95% CI: 0.28-0.53; OR=0.59, 95% CI: 0.40-0.87, respectively). Family history of PCa(OR=7.16, 95% CI: 2.01-25.49), history of prostate diseases(OR=2.28, 95% CI: 1.53-3.41), alcohol consumption(OR=1.97, 95% CI: 1.33-2.90), red meat consumption(OR=1.74, 95% CI: 1.20-2.52), barbecued(OR=2.29, 95% CI: 1.11-4.73) or fried(OR=2.35, 95% CI: 1.24-4.43) foods were related with increased PCa risk. Negative psycho-social factors including occupational setbacks(OR=1.61, 95% CI: 1.00-2.59), marital separation(OR=1.94, 95% CI: 1.29-2.91), self-contained suffering(OR=2.37, 95% CI: 1.58-3.55), and high sensitivity to the personal comments(OR=1.73, 95% CI: 1.18-2.54) were related to PCa. Conclusion Regular consumption of green vegetables and green tea may suggest protective effects on PCa. Alcohol consumption, red meat consumption and barbecued or fried foods were associated with PCa. Negative psycho-social factors may also play a role in the incidence of PCa in Chinese population. | LI Mei Ling LIN Ji HOU Jian Guo XU Lei CUI Xin Gang XU Xing Xing YU Yong Wei HAN Xue WANG Guo Min GUO Jian Ming XU Dan Feng THOMPSON Timothy C CAO Guang Wen ZHANG Hong Wei | 2014 | Biomedical and Environmental Sciences2014,27,9: | 5 |
| 5 | 高血压患者血清磷酸盐与新发高尿酸血症风险的关系显示文摘血清磷酸盐与新发高尿酸血症的关系仍不确定。该研究对中国脑卒中一级预防试验(China stroke primary prevention trial,CSPPT)的尿酸亚组研究进行事后分析,旨在评估血清磷酸盐与新发高血尿酸症的风险之间的关系。研究包括基线尿酸水平正常(<357μmol/L)的参与者共10612人。主要观察指标是新发高血尿酸症,其定义为男性血尿酸浓度≥417或女性≥357μmol/L。在中位数为4.4年的随访期间,1663名(15.7%)参与者发生了新发高尿酸血症。 | 刘莉(译) 叶鹏(摘、审校) Cao J Zhang J Li Q Jiang C Song Y Liu C Liu L Wang B Li J Zhang Y Cui Y Huo Y Wang X Tang G Xu X Qin X | 2019 | 中华高血压杂志2019,27,6: | 2 |
| 6 | Nonlinear Finite Element Simulations to Elucidate the Determinants of Perforator Patency in Propeller Flaps显示文摘 | Chin-Ho Wong Fangsen Cui Bien-Keem Tan Zhuangjian Liu Heow-Pueh Lee C Lu Chee-Liam Foo Colin Song | 2007 | Annals of Plastic Surgery2007,,6: | 2 |
| 7 | Effect of ultrasonic vibration on unmixed zone formation 显示文摘 | Cui Y Xu C L Han Q | 2006 | Scripta Materialia2006,55,11: | 1 |
| 8 | Transfer hydrogenation of activatied C=C bonds catalyzed by ruthenium amido complexes: Reaction scope, limitation, and enantioselectivity 显示文摘 | Xue D Chen Y C Cui X | 2005 | Journal of Organic Chemistry2005,70,9: | 1 |
| 9 | Optical Voltage Sensor Using a Pulse-Controlled Electrooptic Quarter Waveplate 显示文摘 | LI C CUI X YAMAGUCHI I | 2005 | IEEE Transactions on Instrumentation and Measurement2005,54,1: | 1 |
| 10 | Responses of saltcedar (Tamarix chinensis) to water table depth and soil salinity in the Yellow River Delta, China显示文摘 | CUI B S YANG Q C ZHANG K J | 2010 | Plant Ecology2010,209,2: | 1 |
| 11 | Functional nanoscale electronic devices assembled using silicon nanowire buliding blocks显示文摘 | Cui Y Lieber C M | 2001 | Science2001,291,5505: | 1 |
| 12 | The dynamically coursing processes of the microstructures in the nondendritic AlSi7Mg alloy remelted in the semi-solid state 显示文摘 | Mao W M Cui C L Zhao A M | 2000 | Trans Nonferrous Met Soc China2000,10,1: | 1 |
| 13 | Funtional nanoscale electronic devices assembled using silicon nanowire building blocks显示文摘 | Cui Y Lieber C M | 2001 | Science2001,291,: | 1 |
| 14 | Fast Algorithm for Electromagnetic Scattering by Buried 3D Dielectric Objects of Large Size显示文摘 | Cui T J Chew W C | 1999 | IEEE Transactions on Geoscience and Remote Sensing1999,37,5: | 1 |
| 15 | A FAFFA-MLFMA algorithm for electromagnetic scattering 显示文摘 | Chew W C Cui T J Song J M | 2002 | IEEE Trans Antennas and Propagat2002,50,11: | 1 |
| 16 | Reverse osmosis con- centration treatment via a PAC- MF accumulative countercurrent adsorption process显示文摘 | Zhao C X Gu P Cui H Y etal | 2012 | Water Research2012,46,1: | 1 |
| 17 | Molecular detection andsequence analysis of feline Torque teno virus(TTV)in China显示文摘 | ZHU C X SHAN T L CUI L | 2011 | Virus Res2011,156,12: | 1 |
| 18 | Physicochemical propertiesand bactericidal efficiency of neutral and acidic electrolyzed waterunder different storage conditions显示文摘 | CUI X D SHANG Y C SHI Z X | 2009 | Journal of Food Engineering2009,91,4: | 1 |
| 19 | 显示文摘 | Cui Y B Liu C H Hu S Yu X | 2011 | Solar Energy Materials & Solar Cells2011,95,4: | 1 |
| 20 | Removable, fully covered, self- expandable metal stents for the treatment of refractory benign esophagogastric anastomotic strictures 显示文摘 | Liu J Hu Y Cui C | 2012 | Dysphagia2012,27,2: | 1 |