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| 1 | Somatostatin adjunctive therapy for non-variceal upper gastrointestinal rebleeding after endoscopic therapy显示文摘AIM:To evaluate the effect of pantoprazole with a somatostatin adjunct in patients with acute non-variceal upper gastrointestinal bleeding(NVUGIB).METHODS:We performed a retrospective analysis of a prospective database in a tertiary care university hospital.From October 2006 to October 2008,we enrolled 101 patients with NVUGIB that had a high-risk stigma on endoscopy.Within 24 h of hospital admission,all patients underwent endoscopic therapy.After successful endoscopic hemostasis,all patients received an 80-mg bolus of pantoprazole followed by continuous intravenous infusion(8 mg/h for 72 h).The somatostatin adjunct group(n=49)also received a 250-μg bolus of somatostatin,followed by continuous infusion (250μg/h for 72 h).Early rebleeding rates,disappearance of endoscopic stigma and risk factors associated with early rebleeding were examined.RESULTS:Early rebleeding rates were not significantly different between treatment groups(12.2%vs 14.3%,P=0.766).Disappearance of endoscopic stigma on the second endoscopy was not significantly different between treatment groups(94.2%vs 95.9%,P=0.696).Multivariate analysis showed that the complete Rockall score was a significant risk factor for early rebleeding(P =0.044,OR:9.080,95%CI:1.062-77.595).CONCLUSION:The adjunctive use of somatostatin was not superior to pantoprazole monotherapy after successful endoscopic hemostasis in patients with NVUGIB. | Cheol Woong Choi Dae Hwan Kang Hyung Wook Kim Su Bum Park Kee Tae Park Gwang Ha Kim Geun Am Song Mong Cho | 2011 | World Journal of Gastroenterology2011，17，29： | 15 |
| 2 | Significant risk and associated factors of active tuberculosis infection in Korean patients with inflammatory bowel disease using anti-TNF agents显示文摘AIM:To evaluate the incidence and risk factors of Korean tuberculosis(TB) infection in patients with inflammatory bowel disease(IBD) undergoing anti-TNF treatment.METHODS:The data of IBD patients treated with anti-TNFs in 13 tertiary referral hospitals located in the southeastern region of Korea were collected retrospectively.They failed to show response or were intolerant to conventional treatments,including steroids or immunomodulators.Screening measures for latent TB infection(LTBI)and the incidence and risk factors ofactive TB infection after treatment with anti-TNFs were identified.RESULTS:Overall,376 IBD patients treated with antiTNF agents were recruited(male 255,mean age of anti-TNF therapy 32.5±13.0 years);277 had Crohn’s disease,99 had ulcerative colitis,294 used infliximab,and 82 used adalimumab.Before anti-TNF treatment,screening tests for LTBI including an interferon gamma release assay or a tuberculin skin test were performed in 82.2%of patients.Thirty patients(8%)had LTBI.Sixteen cases of active TB infection including one TB-related mortality occurred during 801 personyears(PY)follow-up(1997.4 cases per 100000 PY)after anti-TNF treatment.LTBI(OR=5.76,95%CI:1.57-21.20,P=0.008)and WBC count<5000 mm3(OR=4.5,95%CI:1.51-13.44,P=0.007)during follow-up were identified as independently associated risk factors.CONCLUSION:Anti-TNFs significantly increase the risk of TB infection in Korean patients with IBD.The considerable burden of TB and marked immunosuppression might be attributed to this risk. | Eun Soo Kim Geun Am Song Kwang Bum Cho Kyung Sik Park Kyeong Ok Kim Byung Ik Jang Eun Young Kim Seong Woo Jeon Hyun Seok Lee Chang Heon Yang Yong Kook Lee Dong Wook Lee Sung Kook Kim Tae Oh Kim Jonghun Lee Hyung Wook Kim Sam Ryong Jee Seun Ja Park Hyun Jin Kim | 2015 | World Journal of Gastroenterology2015，21，11： | 5 |
| 3 | EMR for early gastric cancer in Korea: a multicenter retrospective study显示文摘 | Jae J. Kim Jun Haeng Lee Hwoon-Yong Jung Gin Hyug Lee Joo Yong Cho Chang Beom Ryu Hoon Jai Chun Jong Jae Park Wan Sik Lee Hyun Soo Kim Moon Gi Chung Jeong Seop Moon Seok Reyol Choi Geun Am Song Hyun Yong Jeong Sam Ryong Jee Sang Yong Seol Yong Bum Yoon | 2007 | Gastrointestinal Endoscopy2007，，4： | 2 |
| 4 | Cyclooxygenase-2inhibitor reduces simvastatin-induced bone morphogenetic protein-2and bone formation in vivo 显示文摘 | Bradley JD Cleverly DG Bums AM | 2007 | J Periodontal Res2007，，： | 1 |
| 5 | EMR for early gastric cancer in Korea: a multicenter retrospective study显示文摘 | Jae J. Kim Jun Haeng Lee Hwoon-Yong Jung Gin Hyug Lee Joo Yong Cho Chang Beom Ryu Hoon Jai Chun Jong Jae Park Wan Sik Lee Hyun Soo Kim Moon Gi Chung Jeong Seop Moon Seok Reyol Choi Geun Am Song Hyun Yong Jeong Sam Ryong Jee Sang Yong Seol Yong Bum Yoon | 2007 | Gastrointestinal Endoscopy2007，，4： | 1 |
| 6 | Differential gene expression and genomic patient stratification following left ventricular assist device support显示文摘 | Bums CB Bryn MT Canto AM | 2003 | J Am Coll Cardiol2003，41，6： | 1 |
| 7 | Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer:an analysis from the CAPP2 randomised controlled trial显示文摘 | Bum J Gerdes AM Macrae F | 2011 | Lancet2011，378，9809： | 1 |
| 8 | Respiratory protection com- petencies for the occupational health nurse显示文摘 | Bums C Lachat AM Gordon K | 2014 | Workplace Health Saf2014，62，3： | 1 |
| 9 | Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers显示文摘 | Sieuwerts AM Willis S Bums MB | 2014 | Horm Cancer2014，5，6： | 1 |
| 10 | High level expression of p27 (kipl) and cyclin D1 in some human breast cancer cells:inverse correlation between the expression of p27 (kipl) and degree of malignancy inhuman breast and colorectal cancers 显示文摘 | Fredersdorf S Bums J Milne AM et al | 1997 | Proc Natl Acad Sci USA1997，94，12： | 1 |
| 11 | Missed opportunities for earlier HIV diagnosis within primary and secondary healthcare settings in the UK显示文摘 | Bums FM Johnson AM Nazroo J | 2008 | AIDS2008，22，1： | 1 |
| 12 | Missed opportunities for earlier HIV diagnosis within primary and secondary heahhcare settings in the UK显示文摘 | Bums FM Johnson AM Nazroo J | 2008 | AIDS2008，22，1： | 1 |
| 13 | Outcomes of laparoscopic verse open appendectomy显示文摘 | Carboncll AM Bums JM Lincourt AE | | 0，，09： | 1 |
| 14 | Birth of canine offspring following insemination of a bitch with flow-sorted spermatozoa 显示文摘 | Meyers MA Bums G Am D | 2007 | Reprod Fertil Dev2007，20，1： | 1 |
| 15 | Microbial alteration of subsurface natural gas accumulations 显示文摘 | AMES A T BUMS B J | 1984 | AAPG Bulletin1984，68，： | 1 |
| 16 | The applicability of digital PCR for the assessment of detection limits in GMO analysis 显示文摘 | Bums MJ Burrell AM Foy C | 2010 | Eur Food Res Teehnol2010，231，3： | 1 |
| 17 | Cognitive-behavioral therapy for medication-resistant psychosis: a meta-analytic review 显示文摘 | Bums AM Erickson DH Brenner CA | 2014 | Psychiatr Serv2014，65，7： | 1 |
| 18 | Outcomes of laparo- scopic versus open appendectomy 显示文摘 | CarboneII AM Bums JM Lincourt AE | 2004 | Am Surg2004，70，9： | 1 |
| 19 | Staff nurses and students:the good, the bad, and the ugly显示文摘 | Koontz AM Mallory JL Bums JA | 2010 | Med Surg Nurs2010，19，4： | 1 |
| 20 | Response of serum interleukin-6 in patients undergoing elective surgery of varying severity显示文摘 | Cmickshank AM Fraser WD Bums HJ | 1990 | Clin Sci (Lond)1990，79，2： | 1 |
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