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| 1 | Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10)显示文摘Tolerogenic dendritic cells(DCs)are key players in maintaining immunological homeostasis,dampening immune responses,and promoting tolerance.DC-10,a tolerogenic population of human IL-10-producing DCs characterized by the expression of HLA-G and ILT4,play a pivotal role in promoting tolerance via T regulatory type 1(Tr1)cells.Thus far,the absence of markers that uniquely identify DC-10 has limited in vivo studies.By in vitro gene expression profiling of differentiated human DCs,we identified CD141 and CD163 as surface markers for DC-10.The coexpression of CD141 and CD163 in combination with CD14 and CD16 enables the ex vivo isolation of DC-10 from the peripheral blood.CD14+CD16+CD141+CD163+cells isolated from the peripheral blood of healthy subjects(ex vivo DC-10)produced spontaneously and upon activation of IL-10 and limited levels of IL-12.Moreover,in vitro stimulation of allogeneic naive CD4+T cells with ex vivo DC-10 induced the differentiation of alloantigen-specific CD49b+LAG-3+Tr1 cells.Finally,ex vivo DC-10 and in vitro generated DC-10 exhibited a similar transcriptional profile,which are characterized by an anti-inflammatory and pro-tolerogenic signature.These results provide new insights into the phenotype and molecular signature of DC-10 and highlight the tolerogenic properties of circulating DC-10.These findings open the opportunity to track DC-10 in vivo and to define their role in physiological and pathological settings. | Michela Comi Daniele Avancini Francesca Santoni de Sio Matteo Villa Molly Javier Uyeda Matteo Floris Daniela Tomasoni Alessandro Bulfone Maria Grazia Roncarolo Silvia Gregori | 2020 | Cellular & Molecular Immunology2020，17，1： | 4 |
| 2 | Effectiveness of music thera- py for anxiety reduction in women with breast cancer in chemother- apy treatment显示文摘 | Bulfone T Quattrin R Renzo Z | 2009 | Holist Nurs Pract2009，23，4： | 1 |
| 3 | Effectiveness of Music Therapy for Anxiety Reduction in Women With Breast Cancer in Chemotherapy Treatment显示文摘 | Teresa Bulfone Rosanna Quattrin Renzo Zanotti Laura Regattin Silvio Brusaferro | 2009 | Holistic Nursing Practice2009，，4： | 1 |
| 4 | Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-l, Dlx-, and Dlx-1 and --2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches显示文摘 | Qiu M Bulfone A Ghattas I | 1997 | Dev Bio11997，185，2： | 1 |
| 5 | A randomized, controlledtrial of early versus late initiation of dialysis 显示文摘 | Cooper BA Branley P Bulfone L | 2010 | N Engl J Med2010，363，7： | 1 |
| 6 | Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system显示文摘 | Compagnone N A Bulfone A Rubenstein J L Mellon S H | 1995 | Endocrinology1995，136，11： | 1 |
| 7 | MAEG, an EGF- repeat containing gene, is a new marker associated with dermatome specification and morphogenesis of its derivatives显示文摘 | Buchner G Broccoli V Bulfone A | 2000 | Mech Dev2000，98，12： | 1 |
| 8 | Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches 显示文摘 | Qiu M Bulfone A Ghattas I | 1997 | Dev Biol1997，185，2： | 1 |
| 9 | Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain显示文摘 | Qiu M Bulfone A Martinez S | 1995 | Genes Dev1995，9，20： | 1 |
| 10 | The interleukin-15/interleukin-15 receptor system as a model for juxtacrine and reverse signaling显示文摘 | BULFONE PAUS S BULANOVA E BUDAGIAN V | 2006 | Bioessays2006，28，4： | 1 |
| 11 | A randomized, controlled trial of early versus late initiation of dialysis显示文摘 | Cooper BA Branley P Bulfone L | 2010 | N Engl J Med2010，363，7： | 1 |
| 12 | The OSCE method (Objective Structured Clinical Examination) in the university course for nurses in Udine显示文摘 | Bulfone G Zanini A Tosolini C | 2006 | Assist Inferm Rio2006，25，3： | 1 |
| 13 | Id gene expression during development and molecular cloning of the human Idl gene 显示文摘 | Zhu W Dahmen J Bulfone A | 1995 | Brain Res Mol Brain Res1995，30，2： | 1 |
| 14 | TLR signaling in mast cells : common and unique features 显示文摘 | Sandig H Bulfone - Paus Front S | 2012 | Immunol2012，3，： | 1 |
| 15 | The mouse Dlx-2(Tes-1) gene is expressed in spatial y restricted domains of the forebrain,face and limbs in midgestation mouse embryos显示文摘 | Bulfone A Kim HJ Puel es L | | 0，，03： | 1 |
| 16 | A randomized, controlled trial of early versus late initiation of dialysis显示文摘 | Cooper BA Branley P Bulfone L | 2010 | N EnglJ Med2010，363，7： | 1 |
| 17 | Mast cells in allergy: innate instructor of adaptive responses 显示文摘 | Stelekati E Orinska Z Bulfone - Paus S | 2007 | Immunobiology2007，212，6： | 1 |
| 18 | Relation between information,anxiety and satisfaction in oncological andsurgical patients显示文摘 | Bulfone G1 Giavon L Cedolin C | 2006 | Prof Inferm2006，59，1： | 1 |
| 19 | The expression pattern of a mouse doublesex -related gene is consistent with a role in gonadal differentiation显示文摘 | Alessandro De Grandi Vladimiro Calvari Veronica Bertini Alessandro Bulfone Giuliana Peverali Giovanna Camerino Giuseppe Borsani Silvana Guioli | 2000 | Mechanisms of Development2000，，2： | 1 |
| 20 | A randomized,controlled trial of early versus late initiation of dialysis显示文摘 | Cooper BA Branley P Bulfone L | | 0，，： | 1 |
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