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| 1 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 2 | Mood and cognitive effects of transcranial direct current stimulation in post-stroke depression显示文摘 | Bueno VF Brunoni AR Boggio PS | 2011 | Neurocase2011，6，： | 1 |
| 3 | The sertraline vs elec- trical current therapy for treating depression clinical study: re- suits from a factorial, randomized, controlled trial显示文摘 | Brunoni AR Valiengo L Baccaro A | 2013 | JAMA psy- chiatry2013，70，4： | 1 |
| 4 | A systematic review and metaanalysis of clinical studies on major depression and BDNF levels:implications for the role of neuroplasticity in depression显示文摘 | Brunoni AR Lopes M Fregni F | 2008 | Int J Neuropsychopharmacol2008，11，： | 1 |
| 5 | A systematic review on report- ing and assessment of adverse effects associated with transcranial direct current stimulation 显示文摘 | Brunoni AR Amadera J Berbel B | 2011 | Int J Neuropsychopharmacol2011，14，8： | 1 |
| 6 | Clinical- research with transcranial direct current stimulatio(tDCS) :chal- lenges and future directions显示文摘 | Brunoni AR Nitsche MA Bolognini N etal | 2012 | BrainStimul2012，5，17： | 1 |
| 7 | A systematic review and meta-analysis of clinical studies on major depression and BDNF levels:Implications for the role of neuroplasticity in depression显示文摘 | Brunoni AR Lopes M Fregni F | | 0，，： | 1 |
| 8 | A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation显示文摘 | Brunoni AR Amadera J Berbel B | 2011 | Int J Neuropsychopharmacol2011，14，： | 1 |
| 9 | A systematic review and meta-analysis of clinical studies on major depression and BDNF levels:implications for the role of neuroplasticity in depression显示文摘 | Brunoni AR Lopes M Fregni F | | 0，，08： | 1 |
| 10 | Pharmacological and combined interventions for the acute depressive episode:focus on efficacy and tolerability 显示文摘 | BRUNONI AR FRAGUAS R JR FREGNI F | 2009 | Ther Clin Risk Manag2009，5，11： | 1 |
| 11 | Ocular and clinical manifestations of Mobius′syndrome显示文摘 | Cronemberger MF de Castro Moreira JB Brunoni D | | 0，，3： | 1 |
| 12 | Neuromodulation approa- ches for the treatment of major depression: challenges and recom- mendations from a working group meeting 显示文摘 | Brunoni AR Teng CT Correa C | 2010 | Arq Neurop- siquiatr2010，68，3： | 1 |
| 13 | A systematic review and recta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression 显示文摘 | Brunoni AR Lopes M Fregni F | 2008 | Int J Neuropsychopharmacol2008，11，8： | 1 |
| 14 | Clinical trial design in non-invasivc brain stimulation psychiatric research显示文摘 | Brunoni AR Fregni F | 2011 | International Jour-nal of Methods in Psychiatric Research2011，20，2： | 1 |
| 15 | Neuromodulation approaches for the treatment of major depression:challenges and recommendations from a working group meeting显示文摘 | Brunoni AR Teng CT Correa C | 2010 | Arq Neuropsiquiatr2010，68，3： | 1 |
| 16 | Mood and cognitive effects of tran- scranial direct current stimulation in post-stroke depression显示文摘 | Bueno VF Brunoni AR Boggio PS | 2011 | Neurocase2011，6，： | 1 |
| 17 | A systematic re- view on reporting and assessment of adverse effects associ- ated with transcranial direct current stimulation显示文摘 | Brunoni AR Amadera J Berbel B | 2011 | Int J Neuropsychopharmacol2011，14，8： | 1 |
| 18 | Mood and cognitive effects of tr-an- seranial direct current stimulation in post-stroke depression 显示文摘 | Bueno VF Brunoni AR Boggio PS | 2011 | Neurocase2011，17，4： | 1 |
| 19 | A patient with tetrasomy 9p,Dandy-Walker cyst and Hirschsprung disease显示文摘 | Melaragno MI Brunoni D Patr(I)cio FR | 1992 | Ann Genet1992，35，2： | 1 |
| 20 | A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation显示文摘 | Brunoni AR Amadera J Berbel B | 2011 | Int J Neuropsychopharmaco12011，14，8： | 1 |
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