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| 1 | 有机磷农药的使用与污染显示文摘有机磷农药是一类高效、广谱的杀虫剂,广泛地用于农业的防害以及家庭、仓储等的杀虫,但其大量的使用已对地表水、地下水造成普遍污染.本文综述了近年来我国有机磷农药使用状况以及对食物、地表水和地下水污染状况. | 汤亚飞 王焰新 蔡鹤生 Broder J.Merkel | 2004 | 武汉化工学院学报2004，26，1： | 58 |
| 2 | 砷酸盐的溶解度及其稳定性随pH值的变化显示文摘本文讨论了铁、钙和钡的砷酸盐在水环境中的溶解度与稳定性 ,着重分析了砷酸盐在水中发生不一致性溶解与稳定性的关系 .同时藉助PHREEQC程序 ,探讨了砷酸铁溶解时 ,其溶解度、砷的存在形式与pH值的关系 ,以及共存的氢氧化铁对稳定性的影响 ,并作出了Ca As 水和Ba As 水体系的lg[As] | 朱义年 张学洪 解庆林 陈余道 王敦球 Broder Merkel | 2003 | 环境化学2003，22，5： | 35 |
| 3 | 武汉市区第四系含水层地下水有机污染敏感性研究显示文摘在详细调查武汉市水文地质条件和地下水污染现状的基础上 ,获得了高精度的武汉市水环境中微量有机污染物的组成数据 .所检测出的有机组分达 3 0余种 ,以苯及相关苯系物为主 ,污染程度较高的地下水主要分布在人口密集区和工业、商业区 .应用改进的DRASTIC模型———地下水污染敏感性评价模型 ,在GIS平台上 ,编制了武汉市区地下水污染敏感性分区图 .根据其评价结果 ,建议集中对那些敏感性相对较高的区域采取有效的环保措施 。 | 王焰新 李义连 付素蓉 蔡鹤生 Broder Merkel Dana Ihm | 2002 | 地球科学(中国地质大学学报)2002，27，5： | 27 |
| 4 | Gastrointestinal neuroendocrine tumors treated with high dose octreotide-LAR:A systematic literature review显示文摘AIM:To review literature on efficacy and safety of octreotide-long-acting repeatable(LAR)used at doses higher than the Food and Drug Administration(FDA)-approved 30 mg/mo for treatment of neuroendocrine tumors(NETs).METHODS:We searched Pub Med and Cochrane Library from 1998-2012,5 conferences(American Society of Clinical Oncology,Endocrine Society,European Neuroendocrine Tumor Society,European Society for Medical Oncology,North American Neuroendocrine Tumor Society)from 2000-2013 using Me SH and keyterms including neuroendocrine tumors,carcinoid tumor,carcinoma,neuroendocrine,and octreotide.Bibliographies of accepted articles were also searched.Two reviewers reviewed titles,abstracts,and full-length articles.Studies that reported data on efficacy and safety of≥30 mg/mo octreotide-LAR for NETs in human subjects,published in any language were included in the review.RESULTS:The search identified 1086 publications,of which 238 underwent full-text review(20 were translated into English);17 were included in the review.Studies varied in designs,subjects,octreotide-LAR regimens,and definition of outcomes.Eleven studies reported use of higher doses to control symptoms and tumor progression,although symptom severity and formal quality-of-life analysis were not quantitatively measured.Ten studies reported efficacy,describing 260 subjects with doses ranging from 40 mg/mo or 30 mg/3 wk up to 120 mg/mo.Eight studies reported expert clinical opinion that supported dose escalation of octreotide-LAR up to 60 mg/mo for symptom control and suggested increased doses may be effective at preventing tumor progression.Eight studies reported safety;there was no evidence of increased toxicity associated with doses of octreotide-LAR>30 mg/mo.CONCLUSION:As reported in this review,octreotide-LAR at doses>30 mg/mo is being prescribed for symptom and tumor control in NET patients.Furthermore,expert clinical opinion provided support for escalation of somatostatin analogs for refractory hormonal symptoms. | Michael S Broder David Beenhouwer Jonathan R Strosberg Maureen P Neary Dasha Cherepanov | 2015 | World Journal of Gastroenterology2015，21，6： | 8 |
| 5 | 脉冲火焰光度检测器分析水中有机磷农药显示文摘介绍一种新的有机磷农药GC分析检测器PFPD,考查了积分时间、柱流速、进样溶剂对GC/PFPD测定的影响。结果表明,在注入量0.04~2000ng范围内,注入量与GC响应间呈良好的线性关系,最低检出量为甲基对硫磷和对硫磷0.01ng,乐果和敌敌畏0.02ng。GC/PFPD结合固相萃取技术可满足环境水样中微量有机磷农药残留的分析要求。 | 汤亚飞 王焰新 蔡鹤生 Broder J.Merkel | 2005 | 农业环境科学学报2005，24，1： | 8 |
| 6 | 活性炭纤维萃取浓缩水样中微量有机磷农药显示文摘采用活性炭纤维(ACF)为固相萃取剂填料,萃取测定水样中微量有机磷农药。研究分析了ACF用量、洗脱剂类型、农药初始质量浓度、水样过柱速度及pH等因素对萃取回收率的影响。结果表明:洗脱剂类型和ACF用量是显著的影响因素。最佳萃取条件为:含0 1μg L有机磷农药的1L加标水样,需0 2gACF和8mL二氯甲烷,水样过柱速度40mL min。pH对萃取影响不大。萃取回收率为80 7%~118%。 | 汤亚飞 王焰新 蔡鹤生 Broder J.Merkel | 2005 | 环境科学研究2005，18，3： | 5 |
| 7 | 有机磷农药微污染水处理研究显示文摘以活性碳纤维为吸附剂 ,进行了水中微量有机磷农药去除研究 .分批实验结果表明 :活性碳纤维具有良好的吸附性能 ,1 0μg/L混标模拟水 5 L连续通过 0 .2 g ACF吸附柱 ,平均残余质量浓度在 0 .0 2~ 0 .1 | 汤亚飞 王焰新 蔡鹤生 Broder J.Merkel | 2004 | 武汉化工学院学报2004，26，2： | 3 |
| 8 | Appropriateness of systemic treatments in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors显示文摘AIM:To evaluate systemic treatment choices in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors(PNETs)and provide consensus treatment recommendations.METHODS:Systemic treatment options for pancreatic neuroendocrine tumors have expanded in recent years to include somatostatin analogs,angiogenesis inhibitors,inhibitors of mammalian target of rapamycinand cytotoxic agents.At this time,there is little data to guide treatment selection and sequence.We therefore assembled a panel of expert physicians to evaluate systemic treatment choices and provide consensus treatment recommendations.Treatment appropriateness ratings were collected using the RAND/UCLA modified Delphi process.After studying the literature,a multidisciplinary panel of 10 physicians assessed the appropriateness of various medical treatment scenarios on a 1-9 scale.Ratings were done both before and after an extended discussion of the evidence.Quantitative measurements of agreement were made and consensus statements developed from the second round ratings.RESULTS:Specialties represented were medical and surgical oncology,interventional radiology,and gastroenterology.Panelists had practiced for a mean of15.5 years(range:6-33).Among 202 rated scenarios,disagreement decreased from 13.2%(26 scenarios)before the face-to-face discussion of evidence to 1%(2)after.In the final ratings,46.5%(94 scenarios)were rated inappropriate,21.8%(44)were uncertain,and30.7%(62)were appropriate.Consensus statements from the scenarios included:(1)it is appropriate to use somatostatin analogs as first line therapy in patients with hormonally functional tumors and may be appropriate in patients who are asymptomatic;(2)it is appropriate to use everolimus,sunitinib,or cytotoxic chemotherapy therapy as first line therapy in patients with symptomatic or progressive tumors;and(3)beyond first line,these same agents can be used.In patients with uncontrolled secretory symptoms,octreotide LAR doses can be titrated up to 60 mg every4 wk or up to 40 mg every 3 or 4 wk.CONCLUSION:Using the Delphi process allowed physician experts to systematically obtain a consensus on the appropriateness of a variety of medical therapies in patients with PNETs. | Jonathan R Strosberg George A Fisher Al B Benson Lowell B Anthony Bulent Arslan John F Gibbs Edward Greeno Renuka V Iyer Michelle K Kim William J Maples Philip A Philip Edward M Wolin Dasha Cherepanov Michael S Broder | 2015 | World Journal of Gastroenterology2015，21，8： | 2 |
| 9 | A taxonomy of web search显示文摘 | Andrei Broder | 2002 | ACM SIGIR Forum2002，，2： | 2 |
| 10 | Network applications of Bloom Filters : asurvey显示文摘 | Broder A Mitzenmacher M | 2004 | Internet Mathematics2004，1，4： | 1 |
| 11 | Artefill: a permanent skin filler显示文摘 | Broder KW Cohen SR | 2006 | Ex- pert Rev Med Devices2006，3，3： | 1 |
| 12 | Prevention and Control of Influenza with Vaccines Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010显示文摘 | Fiore Anthony E Uyeki Timothy M Broder Karen Finelli Lyn Euler Gary L Singleton James A Iskander John K Wortley Pascale M Shay David K Bresee Joseph S Cox Nancy J | 2010 | MMWR. Morbidity and Mortality Weekly Report2010，，： | 1 |
| 13 | Min-wise independent permutations 显示文摘 | Broder A Z Charikar M Frieze A M | 2000 | Journal of Computer and System Sciences2000，60，3： | 1 |
| 14 | Reliability and convergent and discriminant validity of the Child Oral Health Impact Profile (COHIP Child's version) 显示文摘 | Broder HL Wilson-Genderson M | 2007 | Community Dent Oral Epidemiol2007，35，1： | 1 |
| 15 | Excess lactate: an index ofreversibility of shock in human patients显示文摘 | Broder G Weil MH | 1964 | Science1964，143，3613： | 1 |
| 16 | Impaired synthesis of polyclonal (non-paraprotein) immtmoglobulins by circulating lymphocytes from patients with multiple myeloma: role of suppressor ceils 显示文摘 | Broder S Humphrey R Durm M | 1975 | New Engl J Med1975，293，18： | 1 |
| 17 | Traumatic-induced neuro-toxicity in rat hippocampal neurons显示文摘 | Yoon KW Mitchell HL Broder LD | 1996 | Stroke1996，27，1： | 1 |
| 18 | Questionnaire development:face validity and item impact testing of the Child Oral Health Impact Profile显示文摘 | Broder HL McGrath C Cisneros GJ | 2007 | Community Dent Oral Epidemiol2007，35，1： | 1 |
| 19 | Summary cache: a scalable wide-area Web cache sharing protocol显示文摘 | FAN L CAO P ALMEIDA J BRODER A Z | 2000 | IEEE-ACM Trans on Networking2000，8，3： | 1 |
| 20 | The development of antiretroviraltherapy and its impact on the HIV - 1/AIDSpandemic 显示文摘 | Broder S | 2010 | Antiviral Res2010，85，1： | 1 |
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