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| 1 | Primary hepatic carcinoid:A case report and literature review显示文摘Carcinoids are tumors derived from neuroendocrine cells and often produce functional peptide hormones.Approximately 54.5% arise in the gastrointestinal tract and frequently metastasize to the liver.Primary hepatic carcinoid tumors(PHCT) are extremely rare;only 95 cases have been reported.A 65-year-old man came to our attention due to occasional ultrasound findings in absence of clinical manifestations.His previous medical history,since 2003,included an echotomography of the dishomogeneous parenchymal area but no focal lesions.A computed tomography scan performed in 2005 showed an enhanced pseudonodular-like lesion of about 2 cm.Cholangio-magnetic resonance imaging identified the lesion as a possible cholangiocarcinoma.No positive findings were obtained with positron emission tomography.Histology suggested a secondary localization in the liver caused by a low-grade malignant neuroendocrine tumor.Immunohistochemistry was positive for anti chromogranin antibodies,Ki67 antibodies and synaptophysin.Octreoscan scintigraphy indicated intense activity in the lesion.Endoscopic investigations were performed to exclude the presence of extrahepatic neoplasms.Diagnosis of PHCT was established.The patient underwent left hepatectomy,followed by hormone therapy with sandostatine LAR.Two months after surgery he had a lymph nodal relapse along the celiac trunk and caudate lobe,which was histologically confirmed.The postoperative clinical course was uneventful,with a negative follow-up for hematochemical,clinical and radiological investigations at 18 mo post-surgery.Diagnosis of PHCT is based principally on the histopathological confi rmation of a carcinoid tumor and the exclusion of a non-hepatic primary tumor.Surgical resection is the recommended primary treatment for PHCT.Recurrence rate and survival rate in patients treated with resection were 18% and 74%,respectively. | Luigi Maria Fenoglio Sara Severini Domenico Ferrigno Giovanni Gollè Cristina Serraino Christian Bracco Elisabetta Castagna Chiara Brignone Fulvio Pomero Elena Migliore Ezio David Mauro Salizzoni | 2009 | World Journal of Gastroenterology2009，15，19： | 14 |
| 2 | Venous Lower-Limb Evaluation in Patients With Acute Pulmonary Embolism显示文摘 | Fulvio Pomero Chiara Brignone Cristina Serraino Sergio Panzone Christian Bracco Elena Migliore Paola Dalmasso Paolo Cavallo Perin Luigi Maria Fenoglio | 2011 | Southern Medical Journal2011，，6： | 2 |
| 3 | A phase I pharmaeoki- netic and biological eorrelative study of IMP321, a novel MHC class II agonist, in patients with advanced renal cell carcinoma显示文摘 | Brignone C Escudier B Grygar C | 2009 | Clin Cancer Res2009，15，19： | 1 |
| 4 | SEPIA a Simulator for Electric Power Industry Agents显示文摘 | S A Harp S Brignone B F Wollenberg | 2000 | IEEE Control Systems Magazine2000，20，4： | 1 |
| 5 | Polyubiquitination of p53 by a ubiquitin ligase activity of p300显示文摘 | Grossman S R Deato M E Brignone C | 2003 | Science2003，300，5617： | 1 |
| 6 | Venous lower-limb evalu- ation in patients with acute pulmonary embolism显示文摘 | Pomero F Brignone C Serraino C | 2011 | South Med J2011，104，6： | 1 |
| 7 | The use of the linear sampling method for obtaining super-resolution effects in Born approximation显示文摘 | BRIGNONE M COYLE J PIANA M | 2007 | Journal of Computational and Applied Mathematics2007，203，1： | 1 |
| 8 | Two-dimensional gelanalysis of the proteome of lager brewing yeasts显示文摘 | Joubert R Brignon P Lehmann C | 2000 | Yeast2000，16，6： | 1 |
| 9 | Calculation of energy transacti on allocation factors 显示文摘 | FRADI A BRIGNONE S WOLLENBERG B F | 2001 | IEEE Trans on Power Systems2001，16，2： | 1 |
| 10 | A simulator for electric power industry agents 显示文摘 | HARP S A BRIGNONE S WOLLENBERG B F | 2000 | IEEE Control Systems Magazine2000，20，4： | 1 |
| 11 | Direct detection of viable bacteria, molds, and yeasts by reverse transcriptase PCR in contaminated milk samples after heat treatment显示文摘 | Vaitilingom M Gendre F Brignon P | 1998 | Applied and Environmental Microbiology1998，64，3： | 1 |
| 12 | Polyubiquitination of p53 by a ubiquitin ligase activity of p300 显示文摘 | Grossman SR Deato ME Brignone C | 2003 | Science2003，300，5617： | 1 |
| 13 | Calculation of energy transaction allocation factors 显示文摘 | FRADI A BRIGNONE S WOLLENBERG B F | 2001 | IEEE Transaction on Power Systems2001，16，2： | 1 |
| 14 | An effective approach for high-frequency electromagnetic field- to-line coupling analysis based on regularization techniques 显示文摘 | Brignone M Delfino F Procopio R | 2012 | IEEE Trans Electr Compati2012，54，6： | 1 |
| 15 | Calculation of energy transaction allocation factors显示文摘 | Aniss Fradi Sergio Brignone and Bruce E Wollenberg | 2001 | IEEE Trans on Power Systems2001，16，2： | 1 |
| 16 | Direct detection of viable bacteria,molds,and yeasts by reverse transcriptase PCR in contaminated milk samples after heat treatment显示文摘 | VAITILINGOM M GENDRE F BRIGNON P | 1998 | Appl Environ Microbiol1998，3，64： | 1 |
| 17 | Optimal control and operation of grid-connected photovoltaic production units for voltage support in medium-voltage networks显示文摘 | BONFIGLIO A BRIGNONE M DELFINO F | 2014 | IEEE Trans on Sustainable Energy2014，5，1： | 1 |
| 18 | Influence of aberrations on fundamental mode of high power rod solid-state lasers显示文摘 | Bourderionnet J Brignon A Huignard J P | 2002 | Opt Commun2002，204，： | 1 |
| 19 | Real-time quantitative PCR detection of genetically modified maximizer maize and roundup ready soybean in some representative foods显示文摘 | Pijnenburg H Gendre F Brignon P | 1999 | Agric Food Chem1999，47，： | 1 |
| 20 | Processing valence and intensity of infant expression: The roles of expertise and gender显示文摘 | Proverbio AM Brignone V Matarazzo S | 2007 | Seand J Psychol2007，48，6： | 1 |
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