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| 1 | Prostate volume does not provide additional predictive value to prostate health index for prostate cancer or clinically significant prostate cancer:results from a multicenter study in China显示文摘To evaluate whether prostate volume(PV)would provide additional predictive utility to the prostate health index(phi)for predicting prostate cancer(PCa)or clinically significant prostate cancer,we designed a prospective,observational multicenter study in two prostate biopsy cohorts.Cohort 1 included 595 patients from three medical centers from 2012 to 2013,and Cohort 2 included 1025 patients from four medical centers from 2013 to 2014.Area under the receiver operating characteristic curves(AUC)and logistic regression models were used to evaluate the predictive performance of PV-based derivatives and models.Linear regression analysis showed that both total prostate-specific antigen(tPSA)and free PSA(fPSA)were significantly correlated with PV(all P<0.05).[-2]proPSA(p2PSA)was significantly correlated with PV in Cohort 2(P<0.001)but not in Cohort 1(P=0.309),while no significant association was observed between phi and PV.When combining phi with PV,phi density(PHID)and another phi derivative(PHIV,calculated as phi/PV°5)did not outperform phi for predicting PCa or clinically significant PCa in either Cohort 1 or Cohort 2.Logistic regression analysis also showed that phi and PV were independent predictors for both PCa and clinically significant PCa(all P<0.05);however,PV did not provide additional predictive value to phi when combining these derivatives in a regression model(all models vs phi were not statistically significant,all P>0.05).In conclusion,PV-based derivatives(both PHIV and PHID)and models incorporating PV did not improve the predictive abilities of phi for either PCa or clinically significant PCa. | Da Huang Yi-Shuo Wu Ding-Wei Ye Jun Qi Fang Liu Brian T Helfand Siqun L Zheng Qiang Ding Dan-Feng Xu Rong Na Jian-Feng Xu Ying-Hao Sun | 2020 | Asian Journal of Andrology2020，22，5： | 2 |
| 2 | Mutations in HBV DNA Polymerase Associated with Nucleos(t)ide resistance are Rare in Treatment-na?ve Patients显示文摘 | Philip Vutien Huy N. Trinh Ruel T. Garcia Huy A. Nguyen Brian S. Levitt Khanh Nguyen Eduardo da Silveira Tami Daugherty Aijaz Ahmed Gabriel Garcia Glen A. Lutchman Mindie H. Nguyen | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 1 |
| 3 | Tandem placement of a coronavirus promoter results in enhanced mRNA synthesis from the downstream-most initiation site显示文摘 | Chang RY Brian DA | 1996 | Virology1996，218，2： | 1 |
| 4 | Common RNA replication signals exist among group 2 eoro- naviruses: evidence for in vivo recombination between ani- mal and human eoronavirus molecules 显示文摘 | Wu HY Guy JS Yoo D Vlasak R Urbach E Brian DA | 2003 | Virology2003，315，1： | 1 |
| 5 | Coronavirus genome structure and replication 显示文摘 | Brian DA Baric RS | 2005 | Curr Top Microbiol Immunol2005，287，： | 1 |
| 6 | Tandem placement of a coronavirus promoter results in enhanced mRNA synthesis from the downstream-most initiation site显示文摘 | Chang RY Brian DA | 1996 | Virology1996，218，2： | 1 |
| 7 | Sequence analysis of the bovine coronavirus nucleocapsid and matrix protein genes 显示文摘 | Lapps W Hogue BG Brian DA | 1987 | Virology1987，157，1： | 1 |
| 8 | Chemoim munotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt type lymphoma or acute lymphoblastie leukemia 显示文摘 | Thomas DA Faderl S O' Brian S | 2006 | Cancer2006，106，7： | 1 |
| 9 | Aphylogenetically conserved hairpin-type 3'untranslated region pseudoknot functions in coronavirus RNA replication 显示文摘 | Wlillianms GD Chang RY Brian DA | 1999 | J Virol1999，73，： | 1 |
| 10 | Bovine coronavirus structural proteins 显示文摘 | King B Brian DA | 1982 | J Virol1982，42，2： | 1 |
| 11 | Reconstruction for DRUJ Instability显示文摘 | Ericka L Brian DA | 2007 | HAND2007，2，3： | 1 |
| 12 | A new computational method for hepatic fat microvesicles counting in histological study in rats显示文摘 | Céphora Maria Sabarense Keller Sullivan Oliveira Rocha Damiana Diniz Rosa José Helvecio Martins Marina Maria Lelis da Silva Pereira Fabyano Fonseca Silva Brian Lynn Steward | 2012 | Biochemical and Biophysical Research Communications2012，，2： | 1 |
| 13 | High-risk stress fractures显示文摘 | Steven R. Murray DA Michael T. Reeder Brian E. Udermann Robert W. Pettitt | 2006 | Comprehensive Therapy2006，，1： | 1 |
| 14 | The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP- glucuronosyhransferases 显示文摘 | Brian TE Gail DA Brian B | 2003 | Biochemical Pharmaeology2003，65，： | 1 |
| 15 | Antibiotic prophylaxis and the prevention of surgical site infection显示文摘 | Brian BT Brad WW Patrick DA | 2011 | Current Opinion in Pediatrics2011，23，6： | 1 |
| 16 | Forage production and persistence characteristics of grazed native warm-season grass mixtures with or without nitrogen fertilizer显示文摘Background:Native warm-season grass(NWSG)mixtures may provide a lownitrogen(N)-input summer perennial forage option to extensively managed forage-livestock systems.Methods:Mixed pastures of big bluestem(Andropogon gerardii Vitman),little bluestem(Schizachyrium scoparium Michx.),and indiangrass(Sorghastrum nutans L.)fertilized with 0 or 67 kgNha−1 were continuously stocked with beef heifers and cows.Forage mass,nutritive value,and canopy heights were determined every 2 weeks during the grazing season.Stand persistence measures included the canopy cover and leaf area index(LAI)and plant crown density at spring emergence following 3 years of grazing management.Results:Forage mass,canopy height,and stocking densities were greater for N-fertilized NWSG than unfertilized NWSG for the first 30 days of the growing season across the 3-year study.Forage NWSG fertilized with N had a greater decrease in LAI during the growing season(51%decrease)than unfertilized NWSG.Spring NWSG plant density estimates following 3 years of grazing did not differ across N management strategies.Conclusions:Forage NWSG mixtures supported superior forage attributes and greater stocking densities early in the grazing season under low-level N than zero-N-input systems and may provide a low-N-input alternative for improved species use in southeastern US forage-livestock systems. | Caroline Nicole Chappell Marty Landon Marks Katie Michelle Mason Liliane Severino da Silva Joshua Luke Jacobs Mary Kimberly Mullenix Sandra Leanne Dillard Russell Brian Muntifering | 2022 | Grassland Research2022，1，3： | 0 |
| 17 | 连锁混凝土路面砖透水性路面结构:掺水泥稳定基层材料的研究显示文摘迄今为止,针对混凝土路面砖透水路面(PICP)结构透水基层材料的研究,绝大多集中于采用非粘结颗粒材料上。本文则介绍用于PICP基层、掺水泥作为稳定颗粒材料的试验研究。对一系列使用相同级配集料的水泥稳定颗粒材料,试验研究所得到的路基性能,均优于目前为PICP推荐的基层材料性能。为确定这些因素对路面结构水文和结构性能的影响,对不同颗粒尺寸集料和不同水泥掺加量进行试验。测量孔隙率、渗透率、抗压强度、抗拉强度,以及在三轴荷载反复作用下所获得拉伸弹性模量值,进行了详细叙述;并将这些性能,与以前采用的传统路基材料和透水路基材料的性能,进行了对比。讨论这些研究结果,在PICP设计和施工中有指导意义。结果表明,掺水泥稳定基层材料具有高孔隙率和高渗透率,以及支撑路面足够交通荷载所需要的力学性能。 | OESER Markus SHACKEL Brian DE OLIVEIRA DA LUZ.Glaoco KABITZKE Ute 崔玉忠(译) 杜建东(校) | 2016 | 建筑砌块与砌块建筑2016，，6： | 0 |
| 18 | Outcomes of radical prostatectomy in a 20-year localized prostate cancer single institution series in China显示文摘The long-term survival outcomes of radical prostatectomy(RP)in Chinese prostate cancer(PCa)patients are poorly understood.We conducted a single-center,retrospective analysis of patients undergoing RP to study the prognostic value of pathological and surgical information.From April 1998 to February 2022,782 patients undergoing RP at Queen Mary Hospital of The University of Hong Kong(Hong Kong,China)were included in our study.Multivariable Cox regression analysis and Kaplan–Meier analysis with stratification were performed.The 5-year,10-year,and 15-year overall survival(OS)rates were 96.6%,86.8%,and 70.6%,respectively,while the 5-year,10-year,and 15-year PCa-specific survival(PSS)rates were 99.7%,98.6%,and 97.8%,respectively.Surgical International Society of Urological Pathology PCa grades(ISUP Grade Group)≥4 was significantly associated with poorer PSS(hazard ratio[HR]=8.52,95%confidence interval[CI]:1.42–51.25,P=0.02).Pathological T3 stage was not significantly associated with PSS or OS in our cohort.Lymph node invasion and extracapsular extension might be associated with worse PSS(HR=20.30,95%CI:1.22–336.38,P=0.04;and HR=7.29,95%CI:1.22–43.64,P=0.03,respectively).Different surgical approaches(open,laparoscopic,or robotic-assisted)had similar outcomes in terms of PSS and OS.In conclusion,we report the longest timespan follow-up of Chinese PCa patients after RP with different approaches. | Xiao-Hao Ruan Tsun Tsun Stacia Chun Da Huang Hoi-Lung Wong Brian Sze-Ho Ho Chiu-Fung Tsang Terence Chun-Ting Lai Ada Tsui-Lin Ng Rong Na James Hok-Leung Tsu | 2023 | Asian Journal of Andrology2023，25，3： | 0 |
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