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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | A phase I study of 17 - allylaminogeldanamycin in relapsed/refractory pediatric patients with solid tumors 显示文摘 | Brenda J Weigel Susan M Blaney Joel M Reid | 2007 | Clin Cancer Res2007，13，： | 1 |
| 3 | Stress and the effects of airtransport on flight crews显示文摘 | Brenda JH Ruby M | 2001 | Air ned J2001，20，6： | 1 |
| 4 | An Antifungal Tetrapeptide from the culture of Penicillium canescens 显示文摘 | Brenda V B Nora I P Gabriela M C | 2009 | Chem Biod2009，6，8： | 1 |
| 5 | Rencet Advances on the Nutritional Effects Associated with the Use of Garlic as a Supplement显示文摘 | Harunobu A Brenda LP Hiromichi M et a l | 2001 | American Society for Nutritional Sciences2001，35，： | 1 |
| 6 | Effect of postharvest processing on texture profile analysis of cooked rice 显示文摘 | Elaine T C Brenda G L Bong K M | 1995 | Crereal Chemistry1995，75，2： | 1 |
| 7 | Use of an Arrhenius model to predict rheological behaviour in some australian honeys显示文摘 | BRENDA M BHESH B BRUCE D | 2000 | Lebensm-Wiss u-Technol2000，33，： | 1 |
| 8 | Beneficial effects of breast milk in the neonatal intensive care unit on the developmental outcome of extremely low birth weight infants at 18 months of age显示文摘 | Betty R Brenda B Anna M | 2006 | Pediatrics2006，118，1： | 1 |
| 9 | Why Zijinshan copper bioheapleaching plant works efficiently at low microbial activity-study on leaching kinetics of copper sulfides and its implications 显示文摘 | Ruan R M Zou G Zhong S P Wu Z L Chan Brenda Wang D Z | 2013 | Minerals Engineering2013，48，4： | 1 |
| 10 | Universal parametric geometry repre- sentation method 显示文摘 | Brenda M Kulfan | 2008 | Journal of Aircraft2008，45，1： | 1 |
| 11 | Dynamic changes in the cervical pithelial tight junction complex and differentiation occur during cervical ripening and parturition 显示文摘 | Brenda C Timmon S Shannon M | 2007 | Endocrinology2007，148，3： | 1 |
| 12 | Microbial indicators of faecal contamination in water: a current perspective 显示文摘 | PAM T BRENDA M CASSANDRA L | 2005 | Water Air SoilPollu2005，166，： | 1 |
| 13 | AOT reverse microemulsions in scCO2-a further investigation 显示文摘 | Hutton Brenda H Perera Jilska M | 2001 | Colloidsand Surfaces:2001，189，： | 1 |
| 14 | Communication,love andrelationship satisfaction显示文摘 | Brenda S M Susan S H Clyde Hendrick | 1998 | Journal of Social and PersonalRelationships1998，15，6： | 1 |
| 15 | Economic, Social and Political Globalization and Terrorism显示文摘 | Lutz Brenda J Lutz James M | 2014 | The Journal of Social, Political, and Economic Studies2014，，： | 1 |
| 16 | Single-incision laparoscopic surgery: feasibility for pediat- ric appendectomies 显示文摘 | Sarah C Ohmann Nilda M Garcia Brenda Ventura | 2010 | J Pediatr Surg2010，45，6： | 1 |
| 17 | Attributions to discrimination and self-esteem: Impact of group identification and situational ambiguity 显示文摘 | Brenda M Wendy JQ Toni S | 2003 | JExpSoc Psychol2003，29，3： | 1 |
| 18 | Cytogenetic findings in a case of nodular fasciitis of the breast显示文摘 | Sandra H B Janet M S Brenda M S | 1995 | Cancer Genet Cytogenet1995，81，： | 1 |
| 19 | The costs of caring : Gender identi- fication increases threat following exposure to sexism显示文摘 | Dina E Brenda M Wendy BM | 2010 | J Exp Soe Psychol2010，36，1： | 1 |
| 20 | Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children显示文摘 | Brenda E Amy R M Asa B | 2007 | Environmental Health Perspectives2007，115，5： | 1 |
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