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| 1 | Occult sporadic insulinoma: Localization and surgical strategy显示文摘Insulinomas continue to pose a diagnostic challenge to physicians, surgeons and radiologists alike. Most are intrapancreatic, benign and solitary. Biochemical diagnosis is obtained and imaging techniques to localize lesions continue to evolve. Surgical resection is the treatment of choice. Despite all efforts, an occult insulinoma (occult insulinoma refers to a biochemically proven tumor with indeterminate anatomical site before operation) may still be encountered. New localization preoperative techniques decreases occult cases and the knowledge of the site of the mass before surgery allows to determine whether enucleation of the tumor or pancreatic resection is likely to be required and whether the tumor is amenable to removal via a laparoscopic approach. In absence of preoperative localization and intraoperative detection of an insulinoma, blind pancreatic resection is not recommended. | Bassam Abboud Joe Boujaoude | 2008 | World Journal of Gastroenterology2008，14，5： | 21 |
| 2 | Role of endoscopic ultrasound in diagnosis and therapy of pancreatic adenocarcinoma显示文摘Since its advent more than 20 years ago, endoscopic ultrasound (EUS) has undergone evolution from an experimental to a diagnostic instrument and is now established as a therapeutic tool for endoscopists. Endoscopic ultrasound cannot accurately distinguish benign from malignant changes in the primary lesion or lymph node on imaging alone. With the introduction of the curved linear array echoendoscope in the 1990s, the indications for EUS have expanded. The curved linear array echoendoscope enables the visualization of a needle as it exits from the biopsy channel in the same plane of ultrasound imaging in real time. This allows the endoscopist to perform a whole range of interventional applications ranging from fine needle aspiration (FNA) of lesions surrounding the gastrointestinal tract to celiac plexus block and drainage of pancreatic pseudocyst. This article reviews the current role of EUS and EUS-FNA in diagnosis, staging and interventional application of solid pancreatic cancer. | Joseph Boujaoude | 2007 | World Journal of Gastroenterology2007，13，27： | 10 |
| 3 | Acute mesenteric ischemia after cardio-pulmonary bypass surgery显示文摘Acute mesenteric ischemia (AMI) is a highly-lethal surgical emergency. Several pathophysiologic events (arterial obstruction, venous thrombosis and diffuse vasospasm) lead to a sudden decrease in mesenteric blood flow. Ischemia/reperfusion syndrome of the intestine is responsible for systemic abnormalities, leading to multi-organ failure and death. Early diagnosis is difficult because the clinical presentation is subtle, and the biological and radiological diagnostic tools lack sensitivity and specificity. Therapeutic options vary from conservative resuscitation, medical treatment, endovascular techniques and surgical resection and revascularization. A high index of suspicion is required for diagnosis, and prompt treatment is the only hope of reducing the mortality rate. Studies are in progress to provide more accurate diagnostic tools for early diagnosis. AMI can complicate the post-operative course of patients following cardio-pulmonary bypass (CPB). Several factors contribute to the systemic hypo-perfusion state, which is the most frequent pathophysiologic event. In this particular setting, the clinical presentation of AMI can be misleading, while the laboratory and radiological diagnostic tests often produce inconclusive results. The management strategies are controversial, but early treatment is critical for saving lives. Based on the experience of our team, we consider prompt exploratory laparotomy, irrespective of the results of the diagnostic tests, isthe only way to provide objective assessment and adequate treatment, leading to dramatic reduction in the mortality rate. | Bassam Abboud Ronald Daher Joe Boujaoude | 2008 | World Journal of Gastroenterology2008，14，35： | 9 |
| 4 | Hepatocellular carcinoma in Lebanon: Etiology and prognostic factors associated with short-term survival显示文摘瞄准:在黎巴嫩和早死亡预兆的预示的因素学习 HCC 的传染病学。方法:在一个五年的时期上诊断的 HCC 盒子的观察后续队研究被执行。Multivariate 分析被进行与肝意大利的程序(片断) 分数的癌症相比识别预示的因素。包括内在的肝疾病,病人的人口统计的特征,和孩子呸评估的肝疾病的严厉的病原学的多重变量得分被学习。肿瘤参数包括了小瘤,门静脉血栓的存在,和治疗形式的 HCC, alpha-fetoprotein 水平,数字和尺寸的诊断的时间。后续的死亡或损失被看作一个端点事件。结果:92 个病人(平均数 60.5 +/- 22.3 年) 被包括。内在的疾病的病原学分别地是在 67% , 20% ,和 23.5% 的肝炎 B, C,和酒精。在诊断的孩子呸班分别地是在 34.8% , 39.3% 和 25.8% 的 A, B,和 C。全面幸存分别地在 1, 2 和 3 年是 44.8% , 32.8% 和 17.6%( 吝啬的 F/U 40.2 +/- 23.5 瞬间) 。Multivariate 分析识别了早死亡的三个预言者(<
6 瞬间) :胆红素 >
3.2 mg/dL (P <
0.01 ) , HCC 作为肝疾病的第一个演讲(P = 0.035 ) ,并且肌酸酐 >
1 mg/dL (P = 0.017 ) 。一个分数由考克斯基于这些变量超过了片断分数比例的危险。巨鸟曲线显示了两个模型相等、中等精确。结论:HBV 是在黎巴嫩的 HCC 的领先的原因。早死亡的独立预言者是象疾病的第一表明的提高的胆红素,肌酸酐和 HCC。一个分数的未来的确认基于在预言短期的幸存的这些临床的参数被需要。 | César Yaghi Ala I Sharara Paul Rassam Rami Moucari Khalil Honein Joseph BouJaoude Rita Slim Roger Noun Heitham Abdul-Baki Mohamad Khalifeh Sami Ramia Raymond Sayegh | 2006 | World Journal of Gastroenterology2006，12，22： | 3 |
| 5 | Digestive manifestations of parathyroid disorders显示文摘The parathyroid glands are the main regulator of plasma calcium and have a direct influence on the digestive tract.Parathyroid disturbances often result in unknown long-standing symptoms.The main manifestation of hypoparathyroidism is steatorrhea due to a deficit in exocrine pancreas secretion.The association with celiac sprue may contribute to malabsorption.Hyperparathyroidism causes smooth-muscle atony,with upper and lower gastrointestinal symptoms such as nausea,heartburn and constipation.Hyperparathyroidism and peptic ulcer were strongly linked before the advent of proton pump inhibitors.Nowadays,this association remains likely only in the particular context of multiple endocrine neoplasia type 1/Zollinger-Ellison syndrome.In contrast to chronic pancreatitis,acute pancreatitis due to primary hyperparathyroidism is one of the most studied topics.The causative effect of high calcium level is confirmed and the distinction from secondary hyperparathyroidism is mandatory.The digestive manifestations of parathyroid malfunction are often overlooked and serum calcium level must be included in the routine workup for abdominal symptoms. | Bassam Abboud Ronald Daher Joe Boujaoude | 2011 | World Journal of Gastroenterology2011，17，36： | 2 |
| 6 | Chronic treatment of male rats with daidzein and 17beta-oestradiol induces the contribution of EDHF to endothelium-dependent relaxation显示文摘 | Woodman O L Boujaoude M | 2004 | British Journal of Pharmacology2004，141，2： | 1 |
| 7 | Night and day proteinuria in patients with sleep apnea 显示文摘 | Mello P Franger M Boujaoude Z | 2004 | Am J Kidney Dis2004，44，4： | 1 |
| 8 | Chronic treatment of male rats with daidzein and 17beta - oestradiol induces the contribution of EDHF to endothelium - dependent relaxation显示文摘 | Woodman OL Boujaoude M | 2004 | Br J Pharmacol2004，141，2： | 1 |
| 9 | Endobronchial ultrasound with transbronchial needle aspiration in the diagnosis of bilateral hilar and mediastinal lymphadenopathy显示文摘 | Boujaoude Z Dahdel M Pratter M | 2012 | Journal of Bronchology&Interventional Pulmonology2012，19，1： | 1 |
| 10 | Chronic treatment of male rats with daidzein and 17beta-oestradiol induces the contribution of EDHF to endotheliumdependent relaxation显示文摘 | Woodman OL Boujaoude M | 2004 | Br J Pharmacol2004，141，2： | 1 |
| 11 | Oeeult sporadic insulinoma: localization and surgieal strategy 显示文摘 | Abboud B Boujaoude J | 2008 | World J Gastroenterol2008，14，5： | 1 |
| 12 | Chronic treatment of male rats with daidzein and 17 beta-oestradiol induces the contribution of EDHF to endothelium-dependent relaxation 显示文摘 | WOODMAN O L BOUJAOUDE M | 2004 | Br J Pharmacol2004，141，2： | 1 |
| 13 | Balance of science literacy themes in science cur- ricula:The case of Lebanon显示文摘 | BouJaoude S | 2002 | Intemational Journal of Science Education2002，，24： | 1 |
| 14 | Management of clinically relevant bleeding following endoscopic sphincterotomy显示文摘 | Boujaoude J Pelletier G Fritsch J | 1994 | Endoscopy1994，26，2： | 1 |
| 15 | The ethics of blood donation:does altruism suffice?显示文摘 | Campbell AV Tan C Boujaoude FE | 2012 | Biologicals2012，40，3： | 1 |
| 16 | Vasorelax- ant and antioxidant activity of flavonols and flavones: structure- activity relationships显示文摘 | WOODMAN O L MEEKER W F BOUJAOUDE M | 2005 | Journal of cardiovascular pharmacology2005，46，3： | 1 |
| 17 | Hepatobiliary and Pancreatic: Peliosis hepatis associated with multiple myeloma显示文摘 | R Slim N Hachem V Smayra C Yaghi F Daniel J Boujaoude K Honein R Sayegh M Ghosn | 2014 | J Gastroenterol Hepatol2014，，1： | 1 |
| 18 | The effect of using concept maps as study tools on achievement in chemistry显示文摘 | BouJaoude S Attieh M | 2008 | Eurasia Journal of Mathematics Science & Technology Education2008，4，3： | 1 |
| 19 | Endoscopic Ultrasonographic Diagnosis of Pancreatic Cancer Complicating Chronic Pancreatitis显示文摘 | M. Barthet I. Portal J. Boujaoude J.-P. Bernard J. Sahel | 1996 | Endoscopy1996，，06： | 1 |
| 20 | Pleuroscopic Pleurodesis Combined With Tunneled Pleural Catheter for Management of Malignant Pleural Effusion: A Prospective Observational Study 显示文摘 | Boujaoude Z Bartter T Abboud M | 2015 | J Bronchology Interv Pulmonol2015，22，3： | 1 |
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