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7篇 您的检索式：作者名="Bortsov"

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		题名	作者	年代	出处	被引量
	1	Substantial postopera- tive pain is common among children undergoing laparoscopic ap- pendectomy 显示文摘	Tomecka MJ Bortsov AV Miller NR	2012	Paedialr Anaesth2012，22，2：	1
	2	Association of DASH diet with cardiovascular risk factors in youth with diabetes mellitus: the SEARCH for Diabetes in Youth study 显示文摘	LIESE AD BORTSOV A GUNTHER AL	2011	Circulation2011，123，13：	1
	3	Association of DASH diet with cardiovascular risk factors in youth with diabetes mellitus: the SEARCH for Diabetes in Youth study 显示文摘	Liese A D Bortsov A Gunther A L		Circulation0，123，13：	1
	4	Features of mul- ti-electrode submerged arc welding in the production of high- strength thick-walled pipes显示文摘	Bortsov A N Shabalov I P Velichko A A	2013	METALLURGIST2013，57，34：	1
	5	μ-Opioid Receptor Gene A118G Polymorphism Predicts Survival in Patients with Breast Cancer显示文摘	Andrey V. Bortsov Robert C. Millikan Inna Belfer Richard L. Boortz-Marx Harendra Arora Samuel A. McLean	2012	Anesthesiology2012，，4：	1
	6	Association of DASH diet with cardiovascular risk factors in youth with diabetes mellitus显示文摘	Liese AD Bortsov A Günther AL	2011	Circulation2011，123，13：	1
	7	ApoB-containing lipoproteins promote infectivity of chlamydial species in human hepatoma cell line显示文摘AIM:To evaluate the direct binding of two main chlamydial biovars(C.trachomatis and C.pneumoniae) to plasma lipoproteins and its effect on chlamydial infection rate in human hepatoma cell line(HepG2 cells). METHODS:Murine plasma lipoproteins were fractionated and isolated using fast-performance liquid chromatography(FPLC),spotted on nitrocellulose membrane and incubated with chlamydial suspensions. Direct binding of chlamydial particles to lipoprotein fractions has been studied using lipopolysaccharide-specific antibodies in immuno-dot blot binding assay and immunoprecipitation analysis.Immunostaining protocol as well as flow cytometry analysis have been employed to study the infectivity rate of chlamydial species in HepG2 cells. RESULTS:Elementary bodies of both C.trachomatis and C.pneumoniae bind ApoB-containing fractions of plasma lipoproteins.That binding becomes stronger when heat-denatured FPLC fractions are used, suggesting a primary role of apolipoproteins in interaction between chlamydial particle and lipoprotein. Both chlamydial biovars efficiently propagate in human hepatoma cell line-HepG2 cells even in serum free conditions forming late-stage inclusion bodies and releasing extracellular elementary bodies.Preincubation of C.trachomatis and C.pneumoniae with native ApoB-containing lipoproteins enhances the rate of chlamydial infection in HepG2 cells.CONCLUSION:A productive infection caused by C. trachomatis and C.pneumoniae may take place in human-derived hepatocytes revealing hepatic cells as possible target in chlamydial infection.Obtained results may suggest the participation of lipoprotein receptors in the mechanism of attachment and/or entry of chlamydial particles into target cells.	Yuriy K Bashmakov Nailia A Zigangirova Alexander L Gintzburg Petr A Bortsov Ivan M Petyaev	2010	World Journal of Hepatology2010，2，2：	0

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