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| 1 | Efficacy of cap-assisted colonoscopy according to lesion location and endoscopist training level显示文摘AIM: To evaluate the efficacy of cap-assisted colonoscopy(CAC) for detection of colorectal polyps and adenomas according to the lesion location and endoscopist training level.METHODS: Patients 20 years or older, who underwent their first screening colonoscopy in a single tertiary center from May 2011 to December 2012 were enrolled in this study. All patients underwent either CAC or standard colonoscopy(SC), and all of the procedures were performed by 11 endoscopists(8 trainees and 3 experts). All procedures were performed with highdefinition colonoscopes and narrow band imaging. The eight trainees had experiences of performing 150 to 500 colonoscopies, and the three experts had experiences of performing more than 3000 colonoscopies. A 4-mmlong transparent cap was attached to the end of a colonoscope in the CAC group. We retrospectively evaluated the number of polyps and adenomas, polyp detection rate(PDR), and the number of adenomas and adenoma detection rate(ADR) according to the lesion location and endoscopist training level between CAC and SC. We also evaluated the number of polyps and adenomas according to their size between CAC and SC.RESULTS: Overall, PDR and ADR using CAC were significantly higher than those using SC for both whole colon(48.5% vs 40.7%, P = 0.012; 35.7% vs 28.3%, P = 0.012) and right-side colon(35.3% vs 26.6%, P = 0.002; 27.0% vs 16.9%, P < 0.001). The number of polyps and adenomas per patient using CAC was significantly higher than that using SC for both the whole colon(1.07 ± 1.59 vs 0.82 ± 1.31, P = 0.008; 0.72 ± 1.32 vs 0.50 ± 1.01, P = 0.003) and right-side colon(0.66 ± 1.18 vs 0.41 ± 0.83, P < 0.001; 0.46 ± 0.97 vs 0.25 ± 0.67, P < 0.001). In the trainee group, the PDR and ADR using CAC were significantly higher than those using SC for both the whole colon(46.7% vs 39.7%, P = 0.040; 33.9% vs 26.0%, P =0.012) and right-side colon(34.2% vs 26.5%, P = 0.015; 25.3% vs 15.9%, P = 0.001). In the expert group, the PDR and ADR using CAC were significantly higher than those using SC only for the right-side colon(42.1% vs 27.0%, P =0.035; 36.8% vs 21.0%, P = 0.020).CONCLUSION: CAC is more effective than SC for detection of colorectal polyps and adenomas, especially when performed by trainees and when the lesions are located in the right-side colon. | Dong Jun Kim Hyung Wook Kim Su Bum Park Dae Hwan Kang Cheol Woong Choi Joung Boom Hong Byoung Hoon Ji Chang Seok Lee | 2015 | World Journal of Gastroenterology2015，21，20： | 8 |
| 2 | 左氧氟沙星、加替沙星及莫西沙星对肺结核患者的早期及延长早期杀菌活性显示文摘目的:评估左氧氟沙星、加替沙星及莫西沙星等新氟喹诺酮类药物对肺结核患者的早期杀菌活性及延长早期杀菌活性。设计:随机开放临床试验。40例成年新诊断的涂阳肺结核患者(每组10例)分别每日单一接受异烟肼300mg,或左氧氟沙星1000mg,或加替沙星400mg,或莫西沙星400mg的7天治疗。治疗前2天及单药治疗7天期间,每日收集痰液进行定量培养。计量单药治疗开始的头2天(0-2天)及治疗后5天(2-7天)的菌量下降情况,以评估各药的早期及延长早期杀菌活性。对实验室工作人员关于病人治疗分组信息采用单盲法。结果:异烟肼的早期杀菌活性为0.67log10cfu/毫升/天,高于莫西沙星(0.33log10cfu/毫升/天)及加替沙星(0.35log10cfu/毫升/天)。与每日1000mg左氧氟沙星的早期杀菌活性(0.45log10cfu/毫升/天)相比,无统计学差异(P=0.14)。3种氟喹诺酮类药物的早期杀菌活性(0-2天)与延长早期杀菌活性(2-7天)相似。总体说来,氟喹诺酮类药物的延长早期杀菌活性高于异烟肼。结论:莫西沙星、加替沙星及高剂量左氧氟沙星,虽然略低于异烟肼,但均有良好的早期杀菌活性,并具有较高的延长早期杀菌活性。有理由对这些药物敏感的结核病人进行进一步的治疗研究。 | J. L. Johnson D. J. Hadad W. H. Boom C. L. Daley C. A. Peloquin K. D. Eisenach D. D. Jankus S. M. Debanne E. D. Charlebois E. Maciel M. Palaci R. Dietzet 马玙(译) 屠德华(校) 张立兴(审) | 2006 | 国际结核病与肺部疾病杂志2006，1，2： | 5 |
| 3 | Oxygen and Iron-and Steelmaking:Best Friends and Arch-Enemies显示文摘Ironmaking is the art of removal the arch-enemy oxygen from iron ore by means of carbon reduction and thus producing hot metal.Steelmaking is the art of removing carbon from liquid hot metal by means of best friend pure oxygen,followed by alloying and deoxidation-where oxygen returns to be the arch-enemy.Non-metallic particles in steel such as oxides can have a detrimental effect on the steel product properties in terms of formability,strength and surface properties.An overview of the battle for clean steel production is given based on the experience of the author in industry as well as university research. | BOOM Rob | 2011 | Journal of Iron and Steel Research(International)2011，18，S2： | 4 |
| 4 | Hydro-pyrolysis of lignocellulosic biomass over alumina supported Platinum, Mo2C and WC catalysts显示文摘 | Songbo He Jeffrey Boom Rolf van der Gaast K. Seshan | 2018 | Frontiers of Chemical Science and Engineering2018，12，1： | 4 |
| 5 | Endoscopic resection using band ligation for esophageal SMT in less than 10mm显示文摘AIM:To evaluate the safety and feasibility of endoscopic resection using band ligation(EMR-B) for the diagnostic and therapeutic removal of tumors located in the esophageal subepithelial region having originated from the submucosa.METHODS:From May 2009 to September 2014,after medical chart and endoscopic ultrasonography report review,a total of 15 esophageal tumors located in the submucosal layer were resected by EMR-B.Previous symptom,location,pathology,complete resection rate,incidence of complications,incidence of minor complication,size,length of procedures time and follow up months were evaluated.To evaluate local recurrence at the resection site,periodic follow-up endoscopic examination was undertaken in all of the patients.The first endoscopic examination was performed about 6 mo after the endoscopic resection.Thereafter,the endoscopic follow up were scheduled annually.RESULTS:The mean age was 50.3 ± 9.67 years.The mean tumor size was 6.93 ± 3.15 mm and most of the lesions size was between 5-10 mm in diameter(10/15,66.6%).In all patients,endoscopic en bloc resection was achieved.In one patient,the vertical margin was involved.The mean procedural time was 8.86 ± 3.66 min.In all patients,no evidence of severe complications such as perforation or bleeding occurred.Minor complications such as chest pain(2/15,13.3%) and heartburn(3/15,13.3%) were reported but they symptoms were controlled by proton pump inhibitors,ulcermin and/or analgesics.Histologic assessments of the removed specimens revealed 10 granular cell tumors(66.6%),4 leiomyomas(16.6%) and one lipoma(6.6%).No recurrence was observed during the mean follow up period of 45 ± 3.5 mo(range:5-64 mo).CONCLUSION:EMR-B might be considered safe and effective for the diagnosis and treatment of lesions measuring less than 10 mm in diameter. | Joung Boom Hong Cheol Woong Choi Hyung Wook Kim Dae Hwan Kang Su Bum Park Su Jin Kim Dong Jun Kim | 2015 | World Journal of Gastroenterology2015，21，10： | 3 |
| 6 | Rectal tonsil:A case report and literature review显示文摘The rectal tonsil,a reactive proliferation of lymphoidtissue located in the rectum,is rare.Histologically,benign lymphoid hyperplasia of the rectum is usuallycharacterized by large lymphoid follicles with activegerminal centers and a narrow surrounding mantlezone and marginal zone.This lesion is benign,but must be differentiated from the polypoid type of mucosaassociated lymphoid tissue lymphomas.In the current paper,we present a case of rectal tonsil in a 59-yearold woman.We describe the endoscopic ultrasound imaging findings with literature review. | Joung Boom Hong Hyung Wook Kim Dae Hwan Kang Cheol Woong Choi Su Bum Park Dong Jun Kim Byoung Hoon Ji Kyung Won Koh | 2015 | World Journal of Gastroenterology2015，21，8： | 3 |
| 7 | Analysis of the in vitro degradation and the in vivo tissue response to bi-layered 3D-printed scaffolds combining PLA and biphasic PLA/bioglass components--Guidance of the inflammatory response as basis for osteochondral regeneration显示文摘The aim of the present study was the in vitro and in vivo analysis of a bi-layered 3D-printed scaffold combining a PLA layer and a biphasic PLA/bioglass G5 layer for regeneration of osteochondral defects in vivo Focus of the in vitro analysis was on the(molecular)weight loss and the morphological and mechanical variations after immersion in SBF.The in vivo study focused on analysis of the tissue reactions and differences in the implant bed vascularization using an established subcutaneous implantation model in CD-1 mice and established histological and histomorphometrical methods.Both scaffold parts kept their structural integrity,while changes in morphology were observed,especially for the PLA/G5 scaffold.Mechanical properties decreased with progressive degradation,while the PLA/G5 scaffolds presented higher compressive modulus than PLA scaffolds.The tissue reaction to PLA included low numbers of BMGCs and minimal vascularization of its implant beds,while the addition of G5 lead to higher numbers of BMGCs and a higher implant bed vascularization.Analysis revealed that the use of a bi-layered scaffold shows the ability to observe distinct in vivo response despite the physical proximity of PLA and PLA/G5 layers.Altogether,the results showed that the addition of G5 enables to reduce scaffold weight loss and to increase mechanical strength.Furthermore,the addition of G5 lead to a higher vascularization of the implant bed required as basis for bone tissue regeneration mediated by higher numbers of BMGCs,while within the PLA parts a significantly lower vascularization was found optimally for chondral regeneration.Thus,this data show that the analyzed bi-layered scaffold may serve as an ideal basis for the regeneration of osteochondral tissue defects.Additionally,the results show that it might be able to reduce the number of experimental animals required as it may be possible to analyze the tissue response to more than one implant in one experimental animal. | Mike Barbeck Tiziano Serra Patrick Booms Sanja Stojanovic Stevo Najman Elisabeth Engel Robert Sader Charles James Kirkpatrick Melba Navarro Shahram Ghanaati | 2017 | Bioactive Materials2017，2，4： | 3 |
| 8 | Discrete element method-computational fluid dynamic simulation of the materials flow in an iron making blast furnace显示文摘 | ADEMA A T YANG Y BOOM R | 2010 | ISIJ International2010，50，7： | 1 |
| 9 | Generalised insights in droplet formation at T-junctions through statistical analysis 显示文摘 | Steegmans M L J Schroen C G P H Boom R M | 2009 | Chemical EngineeringScience2009，64，： | 1 |
| 10 | Preparation of double emulsions by membrane emulsification-a review 显示文摘 | van der Graaf S Schroen CGPH Boom RMS | 2005 | J Membr Sci2005，251，12： | 1 |
| 11 | Extended-duration prophylaxis against venous thromboembolism after total hip or knee replacement:a meta anlysis of the randomized trials显示文摘 | Eikel boom JW Quinlan DJ Douketis JD | 2001 | Lancet2001，358，： | 1 |
| 12 | Thermozymes and their applications: a review of recent literature and patents显示文摘 | Bruins M E Janssen A E Boom R M | 2001 | Appl Biochem Biotechnol2001，90，2： | 1 |
| 13 | Current insights into ocular graft-versus-host disease 显示文摘 | Riemens A te Boome L Imhof S | 2010 | Curt Opin Ophthalmol2010，21，6： | 1 |
| 14 | New directions towards structure formation and stability of protein-rich foods from globular proteins显示文摘 | Nanik Purwanti Atze Jan van der Goot Remko Boom Johan Vereijken | 2009 | Trends in Food Science & Technology2009，，2： | 1 |
| 15 | Human cytomegalovirus DNA in plasma and serum speciems of renal transplant reciplents is highly fragmented显示文摘 | Boom R Sol CJ Schuurman T | 2002 | J Clin Microbiol2002，40，11： | 1 |
| 16 | Permit Trading and Credit Trading:A Comparison of Cap-Based and Rate-Based Emissions Trading Under Perfect and Imperfect Competition显示文摘 | Jan-Tjeerd Boom Bouwe R.Dijkstra | | 0，，44： | 1 |
| 17 | The service encounter: di- agnosing favorable and unfavorable incidents 显示文摘 | Bitner M J Booms B H Tetreault M S | 1990 | The Journal of Marketing1990，54，： | 1 |
| 18 | Vertical product differentiation, network externalities, and compatibility decisions 显示文摘 | Baake P Boom A | 2001 | International Journal of Industrial organization2001，19，12： | 1 |
| 19 | Recent advances in the formation of phase inversion membranes made from amorphous or semi-crystalline polymers显示文摘 | Boom R M Beerlage M A M | 1996 | J Membr Sci1996，113，： | 1 |
| 20 | Dynamic externl fixator for pilon fractures in the proximak interphalangeal joints:a simple fixtor for a complex fracture显示文摘 | SYED A A AGARWAL M BOOME R | 2003 | J Hand Surg Br2003，28，2： | 1 |
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