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| 1 | NETosis,complement,and coagulation:a triangular relationship显示文摘NETosis is a regulated form of neutrophil cell death that contributes to the host defense against pathogens and was linked to various diseases soon after its first description in 2004.During NETosis,neutrophils release neutrophil extracellular traps(NETs),which can capture and kill bacteria and other pathogens to prevent them from spreading.Although substantial progress has been made in our understanding of NETosis,the precise mechanism underlying NETosis is still a matter of debate.Research continues to elucidate the molecular pathways involved in NETosis.In recent years,interactions with the complement and coagulation systems have become increasingly apparent.Activated complement proteins can stimulate NET formation,and NETs,in turn,can serve as a platform for complement activation.In addition,NETs can act as a scaffold for thrombus formation during coagulation.While crosstalk between the coagulation and complement systems has been previously described,NETosis appears to be a third important player in this consortium to protect the host against pathogens.This review summarizes our current knowledge on the mutual interactions between NETosis,the complement system and the coagulation system,with an emerging description of their complex triangular relationship. | Cynthia M.de Bont Wilbert C.Boelens Ger J.M.Pruijn | 2019 | Cellular & Molecular Immunology2019，16，1： | 22 |
| 2 | 水通道蛋白对人体皮肤重要性的研究显示文摘目的探讨水通道蛋白(AQPs)在人皮肤表皮上的功能和表达。方法免疫组化法检测30名30~40岁健康的白人女性大腿皮肤AQP3、Claudin-1和CD44表达。检测10名21~60岁亚洲健康妇女的前臂内侧AQP3表达与光暴露关系。结果在人表皮中,AQP3从基底层到粒层均有表达,但在角质层下方开始消失,AQP3和Claudin-1的表达与一种透明质酸盐受体CD44的表达呈负相关。对20~80岁之间的健康女性皮肤间接免疫荧光研究也发现,在衰老和长期慢性光暴露时皮肤AQP3表达会明显减少。结论人类皮肤供水系统缺陷可能与年龄有关,水通道蛋白在维持皮肤正常生理功能等方面具有重要意义。 | Frédéric Bonté Emmanuelle Noblesse Miléne Juan Jean Marc Verbawatz Marc Dumas | 2009 | 中华皮肤科杂志2009，42，5： | 4 |
| 3 | Spectral analysis and fingerprinting for biomedia characterisation显示文摘 | Marie-No?lle Pons Sébastien Le Bonté Olivier Potier | 2004 | Journal of Biotechnology2004，，1： | 2 |
| 4 | Emergence and epidemic occurrence of enterovirus 68 respiratory infections in The Netherlands in 2010显示文摘 | Adam Meijer Sabine van der Sanden Bianca E.P. Snijders Giovanna Jaramillo-Gutierrez Louis Bont Cornelis K. van der Ent Pieter Overduin Shireen L. Jenny Edin Jusic Harrie G.A.M. van der Avoort Gavin J.D. Smith Gé A. Donker Marion P.G. Koopmans | 2011 | Virology2011，，1： | 2 |
| 5 | Eggs of Ephestia kuehniella and Ceratitis capitata, and motile stages of the astigmatid mites Tyrophagus putrescentiae and Carpoglyphus lactis as factitious foods for Orius spp.显示文摘几虚假食物为饲养 anthocorid 食肉动物 Orius thripoborus (Hesse ) 和 Orius naivashae (Poppius ) 被估计(半翅类:Anthocoridae ) 在实验室。当提供了地中海面粉蛾的冻结的鸡蛋时,两 Orius 种的发展、繁殖的特点被检验, Ephestia kuehniella Zeller,冻结的处理鸡蛋 medfly, Ceratitis capitata Wiedemann,或 astigmatid 螨 Tyrophagus putrescentiae (Schrank ) 或 Carpoglyphus lactis (L) 的混合能动阶段。而 C。lactis 和 T。putresecentiae 证明了是为饲养 O 的劣等的食物。thripoborus 和 O。naivashae, C 的鸡蛋。capitata 充分支持了两个食肉动物的开发和复制。结果在上 medfly 鸡蛋类似于 E 上的那些或稍微劣等。kuehniella 鸡蛋,它是为 culturing 的标准食物这些 anthocorid 臭虫。O。thripoborus 能在 C 上为 4 连续的代被维持。capitata 鸡蛋显示那 medfly 处理了鸡蛋能是 E 的一种合适、更便宜的选择。为这些 Orius spp 高耸延长的 kuehniella 鸡蛋。 | Jochem Bonte Anais Van de Walle Des Conlong Patrick De Clercq | 2017 | Insect Science2017，24，4： | 2 |
| 6 | Fitness and predation potential of Macrolophus pygmaeus reared under artificial conditions显示文摘在当植物材料不在时高耸延长以后的 Macrolophus pygmaeus Rambur 的生物参数与通常饲养植物的食肉动物的那些相比。当 Ephestia kuehniella Zeller 的鸡蛋作为食物被提供时, M 的发展、繁殖的健康。用人工的生活和 oviposition 底层为超过 30 连续的代饲养的 pygmaeus 类似于坚持的食肉动物的烟草叶子。饲养 Plantless 食肉动物的第五中间形态也在烟草蚜虫的第二中间形态上有类似的 predation 率, Myzus persicae nicotianae Blackman,他们在植物材料上维持的同伴。在一个进一步的实验,由第五中间形态 M 的蚜虫猎物上的 predation。pygmaeus 喂了二个鸡蛋之一基于蛋黄的人工的食谱与美女的相比喂的 E。kuehniella 鸡蛋。尽管有他们的更低的身体重量,当他们的对应物在鳞翅类的卵上高耸了,食肉动物在人工的饮食杀死了的任何一个上生产了猎物的类似的数字。我们的学习显示人工的高耸系统可能是有用的进一步文饰这个经济地重要的生物控制代理人的生产。 | Bjorn Vandekerkhove Veronic De Puysseleyr Maarten Bonte Patrick De Clercq | 2011 | Insect Science2011，18，6： | 2 |
| 7 | Hyperlipoproteinemia enhances susceptibility to acute disseminated Candida albicans infection in low-density-lipoprotein-receptor-deficient mice 显示文摘 | Netea MG Demacker PN de Bont N | 1997 | Infect Immun1997，65，7： | 2 |
| 8 | 世界家庭医生组织(WONCA)研究论文摘要汇编——帕金森病患者对诊断流程不满意度影响因素的横断面调查研究显示文摘背景帕金森病(PD)的诊断流程通常比较复杂。诊断流程可以影响到患者的自信、就医满意度以及对医务人员的信任情况。尽管诊断结果对患者造成的影响与医务人员无关,但是医务人员可以影响患者在诊断流程中的感受。本研究旨在调查PD患者对诊断流程的不满意度并探究相关影响因素。方法本项横断面研究在902例来自于荷兰帕金森病协会的PD患者中开展。每例患者均被要求书写其诊断流程。采用自行设计的赋值表对数据进行整理。各整理者之间的误差情况采用Cohen's kappa系数进行评价。使用χ~2检验和多因素Logistic回归分析评估患者对诊断流程的不满意度与性别、文化程度、诊断流程时长、患者与全科医生及神经科医生的沟通情况、参与诊断医务人员人数、是否存在二次诊断(包括提出进行二次诊断者)以及延迟诊断(患者认为有人导致了其延迟诊断也考虑在内)之间的关系。采用亚组分析探究不同性别患者对诊断流程不满意度之间的差异。结果 16.4%的PD患者明确表示对诊断流程不满意,4.8%的患者表示对诊断流程很满意。各整理者之间的误差情况Cohen's kappa系数为0.82。患者文化程度较低、参与诊断医务人员超过必要人数1人以上、患者提出进行二次诊断以及由医务人员原因导致的延迟诊断是PD患者对诊断流程不满意的危险因素。当只有全科医生与神经科医生参与诊断时,女性患者对诊断流程的不满意程度超过男性患者。结论 PD患者对诊断流程的不满意度与较低文化程度、患者提出进行二次诊断以及延迟诊断相关。了解这些因素后,如全科医生特别注意与患者进行沟通并且与患者一起进行临床决策,可以减少患者在诊断流程中的不良感受。此举有利于增加患者对医生的信任度,而患者对医生的信任度在以后的治疗过程中极其重要。 | PLOUVIER A O A OLDE HARTMAN T C DE BONT O A 本刊编辑部 | 2017 | 中国全科医学2017，20，29： | 2 |
| 9 | Normal cartilage structure,biochemistry and metabolism显示文摘 | Bont LGM Boering G | 1995 | J Oral Maxillofac Surg1995，53，： | 1 |
| 10 | Recent developments in the biochemistry and ecology of enhanced biological phosphorus removal 显示文摘 | KORTSTEE G J APPELDOORN K J BONTING C F C | 2000 | Biochemistry Moscow2000，65，3： | 1 |
| 11 | Monocyte interleukin-12 production is inversely related to duration of respiratory failure in respiratory syncytial virus bronchiolitis显示文摘 | Bont L Kavelaars A Heijnen CJ | 2000 | J Infect Dis2000，181，5： | 1 |
| 12 | Stimulation of Fibroblasts glycosaminoglycan synthesis by Eriobotrya japonica extact显示文摘 | Bonte Frederic Dumas Marc Petit Veronique | 2001 | Revista Boliviana de Quimica2001，18，1： | 1 |
| 13 | Bone marrow-derived cells and tumor growth:contribution of bone marrow-derived cells to tumor micro-environments with special focus on mesenchymal stem cells显示文摘 | Roorda BD Ter Elst A Kamps WAde Bont ES | 2009 | Critical Reviews in Oncology/Hematology2009，69，3： | 1 |
| 14 | Formation of spinels in cosmic objects during atmospheric entry: A clue to the Cretaceous-Tertiary boundary event显示文摘 | Robin E Bonte P Froget L | 1992 | Earth and Planetary Science Letters1992，108，4： | 1 |
| 15 | Enantioseparation of ben- zoxazolinone aminoalcohols and their aminoketone precur- sors, potential adrenergic ligands, by analytical and prepara- tive liquid chromatography on amylose chiral stationary phases and characterization of the enantiomers 显示文摘 | Lipka E Vaccher C Bonte J P | 2009 | Chirality2009，21，8： | 1 |
| 16 | Monocyte IL-10 production during respiratory syncytial virus bronchiolitis is associated with recurrent wheezing in a one-year follow-up study显示文摘 | Bont L Heijnen CJ Kavelaars A | | 0，，05： | 1 |
| 17 | Evidence based selection of housekeeping genes显示文摘 | de Jonge H J Fehrmann R S de Bont E S Hofstra R M Gerbens F Kamps W A de Vries E G van der Zee A G te Meerman G J ter Elst A | | 0，，： | 1 |
| 18 | Cutaneous bioavailability in hairless rats of tretinoin in liposomes or gel 显示文摘 | MASINI V BONTE F MEYBECK A | 1993 | Pharm Sci1993，82，1： | 1 |
| 19 | Coping style and de- pression level influence outcome in in - vitro fertilization 显示文摘 | Demyttenaere K Bonte L Gbeldof M | 1998 | Fertil Steril1998，69，6： | 1 |
| 20 | Subclassification of fractures of the condylar process of the mandible 显示文摘 | Loukota RA Eckelt U De Bont L | 2005 | Br J Oral Maxillofac Surg2005，43，1： | 1 |
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