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| 1 | Emerging Organic Contaminants in Chinese Surface Water:Identification of Priority Pollutants显示文摘The occurrence and impacts of emerging organic contaminants(EOCs)in the aquatic environment have gained widespread attention over the past two decades.Due to large number of potential contaminants,monitoring campaigns,treatment plants,and proposed regulations should preferentially focus on specific pollutants with the highest potential for ecological and human health effects.In the present study,a multi-criteria screening approach based on hazard and exposure potentials was developed for prioritization of 405 unregulated EOCs already present in Chinese surface water.Hazard potential,exposure potential,and risk quotients for ecological and human health effects were quantitatively analyzed and used to screen contaminants.The hazard potential was defined by contaminant persistence,bioaccumulation,ecotoxicity,and human health effects;similarly,the exposure potential was a function of contaminant concentration and detection frequency.In total,123 compounds passed the preselection process,which involved a priority index equal to the normalized hazard potential multiplied by the normalized exposure potential.Based on the prioritization scheme,11 compounds were identified as top-priority,and 37 chemicals were defined as high-priority.The results obtained by the priority index were compared with four other prioritization schemes based on exposure potential,hazard potential,or risk quotients for ecological effects or human health.The priority index effectively captured and integrated the results from the more simplistic prioritization schemes.Based on identified data gaps,four uncertainty categories were classified to recommend:①regular monitoring,derivation of environmental quality standards,and development of control strategies;②increased monitoring;③fortified hazard assessment;and④increased efforts to collect occurrence and toxicity data.Overall,20 pollutants were recommended as priority EOCs.The prioritized list of contaminants provides the necessary information for authoritative regulations to monitor,control,evaluate,and manage the risks of environmentally-relevant EOCs in Chinese surface water. | Mengmeng Zhong Tielong Wang Wenxing Zhao Jun Huang Bin Wang Lee Blaney Qingwei Bu Gang Yu | 2022 | Engineering2022，8，4： | 3 |
| 2 | Resemblance of osteophytes in experimental osteoarthritts to transforming growth factor beta-induced osteophytes:Limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation显示文摘 | Blaney Davidson EN Vitters EL van Beuningen HM | 2007 | Arthritis Rheum2007，56，12： | 1 |
| 3 | Methadone maintenance: Does dose determine differences in outcome 显示文摘 | Blaney T Craig RJ | 1999 | J Subst Abuse Treat1999，16，3： | 1 |
| 4 | Responses of Spodoptera littoralis larvae to Tunisian plant extracts and to neo-clerodane diterpenoids isolated from Ajuga pseudoiva leaves显示文摘 | H Ben Jannet F Harzallah-Skhiri Z Mighri M.S.J Simmonds W.M Blaney | 2000 | Fitoterapia2000，，2： | 1 |
| 5 | A phase I study of 17 - allylaminogeldanamycin in relapsed/refractory pediatric patients with solid tumors 显示文摘 | Brenda J Weigel Susan M Blaney Joel M Reid | 2007 | Clin Cancer Res2007，13，： | 1 |
| 6 | Atypical teratoid/rhabdoid tumor of the central nervous system:report on workshop显示文摘 | Packer R J Biegel J A Blaney S | 2002 | J Pediatr Hematol Oncol2002，4，5： | 1 |
| 7 | Clinical pharmacology of encapsula- ted sustained release cytarabine 显示文摘 | MURRY DJ BLANEY SM | 2000 | Ann Pharmacother2000，34，10： | 1 |
| 8 | Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD- 2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation显示文摘 | Blaney Davidson EN Vitters EL van der Kraan PM | 2006 | Ann Rheum Dis2006，65，： | 1 |
| 9 | Responses of pigs fedwheat naturally infected with Fusarium gram inearum and containing the mycotoxins 4 - de- ~xynivalenol and zearalenone显示文摘 | William S K C Blaney B J Magee M H | 1988 | Australian Jounal of Agricultural Research1988，39，6： | 1 |
| 10 | Acute reperfusion thera- py in ST-elevation myocardial infarction from 1994 显示文摘 | Nallamothu BK Blaney ME Morris SM | 2007 | Am J Med2007，120，8： | 1 |
| 11 | TGF- beta and osteoarthriti显示文摘 | Blaney - Davidson EN Vander Kraan PM Van den Berg WB | 2007 | Osteoarthritis Cartilage2007，15，： | 1 |
| 12 | A phase I study of 17-allyl- aminogeldanamycin in relapsed/refractory pediatric patients with solid tumors:a Children's Oncology Group study 显示文摘 | Weigel B J Blaney SM Reid JM | 2007 | Clin Cancer Res2007，13，6： | 1 |
| 13 | Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes:limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation显示文摘 | Blaney Davidson EN Vitters EL van Beuningen HM | | 0，，12： | 1 |
| 14 | A phase Ⅰ trial and pharmacokinetic study of aflibercept (VEGF Trap) in children with refractory solid tumors:a children's oncology group phase Ⅰ consortium report显示文摘 | Glade Bender J Blaney SM Borinstein S | | 0，，18： | 1 |
| 15 | Neoplasticmeningtis:diagnosis and treatment considerations显示文摘 | Blaney SM Poplack DG | 2000 | Med 0nco2000，17，： | 1 |
| 16 | Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2(BMP-2)stimulation point toward a role for BMP-2 in cartilage repair and remodeling显示文摘 | Blaney Davidson EN Vitters EL van Lent PL | 2007 | Arthritis Res Ther2007，9，5： | 1 |
| 17 | Responses of pigs fed wheat naturally infected with Fusarium graminearum and containing the mycotoxins 4-deoxynivalenol and zearalenone显示文摘 | Williams K C Blaney B J Magee M H | 1988 | Aus J of Agr Res1988，39，6： | 1 |
| 18 | Methadone maintenance does dose determine differences in outcome显示文摘 | Blaney T Craig R | 1999 | J Subst Abuse Treat1999，16，3： | 1 |
| 19 | Differences in the central nervous system distribution and pharmacology of the mouse 5-hydroxytryp tamine-6 receptor compared with rat and human receptors investigated by radioligand binding,site-directed mutagenesis,and molecular modeling显示文摘 | Hirst WD Abrahamsen B Blaney FE | | 0，，06： | 1 |
| 20 | Vaccine candidates derived from a novel infectious CDNA clone of an American genotype dengue virus type 显示文摘 | Blaney JEJR Hanson CT Hanley KA | 2004 | BMC Infect Dis2004，4，1： | 1 |
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