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| 1 | The dynamics of the piglet gut microbiome during the weaning transition in association with health and nutrition显示文摘Background: Understanding the composition of the microbial community and its functional capacity during weaning is important for pig production as bacteria play important roles in the pig's health and growth performance. However,limited information is available regarding the composition and function of the gut microbiome of piglets in early-life.Therefore, we performed 16 S rRNA gene and whole metagenome shotgun sequencing of DNA from fecal samples from healthy piglets during weaning to measure microbiome shifts, and to identify the potential contribution of the early-life microbiota in shaping piglet health with a focus on microbial stress responses, carbohydrate and amino acid metabolism.Results: The analysis of 16 S rR NA genes and whole metagenome shotgun sequencing revealed significant compositional and functional differences between the fecal microbiome in nursing and weaned piglets. The fecal microbiome of the nursing piglets showed higher relative abundance of bacteria in the genus Bacteroides with abundant gene families related to the utilization of lactose and galactose. Prevotel a and Lactobacil us were enriched in weaned piglets with an enrichment for the gene families associated with carbohydrate and amino acid metabolism. In addition, an analysis of the functional capacity of the fecal microbiome showed higher abundances of genes associated with heat shock and oxidative stress in the metagenome of weaned piglets compared to nursing piglets.Conclusions: Overal, our data show that microbial shifts and changes in functional capacities of the piglet fecal microbiome resulted in potential reductions in the effects of stress, including dietary changes that occur during weaning.These results provide us with new insights into the piglet gut microbiome that contributes to the growth of the animal. | Robin B.Guevarra Sang Hyun Hong Jin Ho Cho Bo-Ra Kim Jiwon Shin Jun Hyung Lee Bit Na Kang Young Hwa Kim Suphot Wattanaphansak Richard E.Isaacson Minho Song Hyeun Bum Kim | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 16 |
| 2 | Piglet gut microbial shifts early in life:causes and effects显示文摘The gut microbiome has long been known to play fundamentally important roles in the animal health and the well-being of its host. As such, the establishment and maintenance of a beneficial gut microbiota early in life is crucial in pigs, since early gut colonizers are pivotal in the establishment of permanent microbial community structures affecting the health and growth performance of pigs later in life. Emphasizing this importance of early gut colonizers, it is critical to understand the factors impacting the establishment of the piglet gut microbiome at weaning. Factors include, among others, diet, in-feed antibiotics, probiotics and prebiotic administration. The impact of these factors on establishment of the gut microbiome of piglets at weaning includes effects on piglet gut microbial diversity, structure, and succession. In this review, we thoroughly reviewed the most recent findings on the piglet gut microbiome shifts as influenced by weaning, and how these microbiome changes brought about by various factors that have been shown to affect the development of microbiota in piglets. This review will provide a general overview of recent studies that can help to facilitate the design of new strategies to modulate the gut microbiome in order to enhance gastrointestinal health, growth performance and well-being of piglets. | Robin B.Guevarra Jun Hyung Lee Sun Hee Lee Min-Jae Seok Doo Wan Kim Bit Na Kang Timothy J.Johnson Richard E.Isaacson Hyeun Bum Kim | 2019 | Journal of Animal Science and Biotechnology2019，10，3： | 13 |
| 3 | 浅液深和挡板影响下遭受横摇激励的晃荡问题数值研究显示文摘Sloshing is relevant in several applications like ship tanks,space and automotive industry and seiching in harbours.Due to the relationship between ship and sloshing motions and possibility of structural damage,it is important to represent this phenomenon accurately.This paper investigates sloshing at shallow liquid depths in a rectangular container using experiments and RANS simulations.Free and forced sloshing,with and without baffles,are studied at frequencies chosen specifically in proximity to the first mode natural frequency.The numerically calculated free surface elevation is in close agreement with observations from experiments.The upper limit of the resonance zone,sloshing under different filling depths and roll amplitudes and sloshing with one,two and four baffles are also investigated.The results show that the extent of the resonance zone is reduced for higher filling depth and roll amplitude.It is also found that the inclusion of baffles moves the frequency at which the maximum free surface elevation occurs,away from the fundamental frequency.Finally,a submerged baffle is found to dissipate more energy compared to a surface piercing baffle and that the effect of several submerged baffles is similar to that of a single submerged baffle. | Arm Kamath Erlend Linvdée Grotle Hams Bits | 2021 | Journal of Marine Science and Application2021，20，2： | 2 |
| 4 | Synthesis, characterization and catalytic activity of cobalt phthalocyanine tetrasulphonamide in sweetening of LPG 显示文摘 | Gautam Das Bit Sain Sunil Kumar | 2009 | Catalysis Today2009，141，： | 1 |
| 5 | Tissue engineered regeneration of completely transected spinal cord using human mesenchymal stem cells显示文摘 | Kkot Nim Kang Da Yeon Kim So Mi Yoon Ju Young Lee Bit Na Lee Jin Seon Kwon Hyo Won Seo Il Woo Lee Ha Cheol Shin Young Man Kim Hyun Soo Kim Jae Ho Kim Byoung Hyun Min Hai Bang Lee Moon Suk Kim | 2012 | Biomaterials2012，，19： | 1 |
| 6 | High concentration coal water slurry from Indian coals u-sing newly developed additives显示文摘 | Kaushal K Tiwari Sibendra K Basu Kumaresh C Bit | 2004 | Fuel Processing Tech nology2004，85，1： | 1 |
| 7 | Development of a Symptom Specific Health Status Measure for Patients with Chronic Cough: Leicester Cough Questionnaire ( LCQ ) 显示文摘 | Bitting S S Prudon B Carr A J | 2003 | Thorax2003，58，： | 1 |
| 8 | Feature fusion of side face and gait for videobased human identification 显示文摘 | Zhou Xiao-li Bit Bhanu | 2008 | Pattern Recognition2008，41，3： | 1 |
| 9 | Post stroke depression : epidemiology, pathophysiology,and biological treatment 显示文摘 | Whyte EM Mulsant BIt | 2002 | Biol Psychiatry2002，52，3： | 1 |
| 10 | Evolving treatment strategies for gallbladder cancer 显示文摘 | Hueman biT Vollmer CM Jr Pawlik TIM | 2009 | Ann Surg Oncol2009，16，8： | 1 |
| 11 | Effects of nigrostriatal denervation and L-dope therapy on the GABAergie neurons in the striatum in MPTP - treated monkeys and Parkinson's disease: an in sltu hybridization study of GAD67 mRNA 显示文摘 | Levy R Herrero biT Ruberg M et ul | 1995 | Eur j Neurosei1995，7，6： | 1 |
| 12 | Xenotransplant cardiac chimera : im2mune tolerance of adult stem cells 显示文摘 | Saito T Bruder SP Bit'tim B | 2002 | Ann Thomc Surg2002，74，1： | 1 |
| 13 | Differential expression of matrix metalloproteinases and their tissue inhibitors at the ad- vancing pterygium head显示文摘 | Di Girolamo N Wakefield D Coroneo biT | 2000 | Invest Ophthalmol Vis Sci2000，41，13： | 1 |
| 14 | Fuzzy programming approach to multi -criteria decision making transportation problem显示文摘 | Bit A K Biswal M P Alam S S | | 0，，01： | 1 |
| 15 | Fuzzy programming approach to multi -objective solid transportation problem显示文摘 | Bit A K Biswal M P Alam S S | | 0，，02： | 1 |
| 16 | Emerging role of PKA/eNOS path- way in therapeutic angiogenesis for isehaemie tissue diseases 显示文摘 | Bit SC Xiong Y Kevil CG | 2012 | Cardiovase Res2012，95，1： | 1 |
| 17 | An additive fuzzy programming model for multi -objective transportation problem显示文摘 | Bit A K Biswal M P Alam S S | | 0，，03： | 1 |
| 18 | High-concentration Coal-water Slurry from Indian Coals Using Newly Developed Additives 显示文摘 | Tiwari K K Basu S K Bit K C | 2003 | Fuel Processing Techno- logy2003，85，1： | 1 |
| 19 | Emerging role of PKA/eNOS pathway in therapeutic angiogenesis for ischaemie tissue diseases 显示文摘 | Bit SC Xiong Y Kevil CG | 2012 | Cardiovasc Res2012，95，1： | 1 |
| 20 | The modified 'hanging maneuver' during orthotopic liver transplantation using a technique for conserving the inferior vena cava显示文摘 | Ettorre GM Vennarocci G Lonardo biT | 2003 | Tumori2003，89，4： | 1 |
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