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| 1 | In vitro effects of Salvia officinalis L.essential oil on Candida albicans显示文摘Objective:To determine the anticandidal activities of Salvia officinalis L.(S.officinalis)essential oil against Candida albicans(C.albicans)and the inhibitory effects on the adhesion of C.albicans to polymethyl methacrylate(PMMA)resin surface.Methods:Disc diffusion method was first used to test the anticandidal activities of the S.officinalis L.essential oil against the reference strain(ATCC 90028)and 2 clinical strains of C.albicans.Then the minimal inhibitory concentration(MIC)and minimal lethal concentration(MLX)were determined by modified membrane method.The adhesion of C.albicans to PMMA resin surface was assessed after immersion with S.officinalis L.essential oil at various concentrations of 1XMIC.0.5XMIC and 0.25XMIC at room temperature for30 min.One-way ANOVA was used to compare the Candida cell adhesion with the pretreatment agents and Tukey's test was used for multiple comparisons.Results:5.officinalis L.essential oil exhibited anticandidal activity against all strains of C.albicans with inhibition zone ranging from 40.5 mm to 19.5 mm.The MIC and MLC of the oil were determined as 2.780 g/L against all test strains.According to the effects on C.albicans adhesion to PMMA resin surface,it was found that immersion in the essential oil at concentrations of 1XMIC(2.780 g/L).0.5XMIC(1.390 g/L)and0.25XMIC(0.695 g/L)for 30 min significantly reduced the adhesion of all 3 test strains to PMMA resin surface in a dose dependent manner(P<0.05).Conclusions:S.officinalis L.essential oil exhibited anticandidal activities against C.albicans and had inhibitory effects on the adhesion of the cells to PMMA resin surface.With further testing and development,S.officinalis essential oil may be used as an antifungal denture cleanser to prevent candidal adhesion and thus reduce the risk of candida-associated denture stomatitis. | Tularat Sookto Theerathavaj Srithavaj Sroisiri Thaweboon Boonyanit Thaweboon Binit Shrestha | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，5： | 2 |
| 2 | In vitro antimicrobial effects of grape seed extract on peri-implantitis microflora in craniofacial implants显示文摘Objective:To determine the antimicrobial effects of grape seed on peri-implantitis microflora.Methods:The grape seed extract was tested against peri-implantitis microflora most commonly found in craniofacial implants including reference strains of Staphylococcus aureus(S.aureus),Escherichia coli(E.coli),Candida albicans(C.albicans)and clinical strains of S.aureus,Klebsiella pneumonia(K.pneumonia)and Candida parapsilosis(C.parapsilosis)by disk diffusion test.Minimum inhibitory concentrations(MIC)and minimum cidal concentrations(MCC)were determined using modified agar dilution millpore method.The extract was further combined with polyethylene glycol and propylene glycol,and was tested for antimicrobial effects.Results:Grape seed extract showed positive inhibitory effects with S.aureus at MIC of 0.625 mg/mL and MCC of1.25 mg/mL respectively.However the extracts showed minimal or no reactivity against strains of E.coli,K.pneumonia,C.parapsilosis and C.albicans.The use of grape seed extract in combination with polyethylene glycol and propylene glycol also showed dose dependent inhibitory effect on S.aureus.Conclusions:The results of the study showed that grape seed has potential antimicrobial effects which can be further studied and developed to be used in the treatment of infected skinabutment interface of craniofacial implants. | Binit Shrestha M.L.Srithavaj Theerathavaj Sroisiri Thaweboon Boonyanit Thaweboon | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，10： | 1 |
| 3 | Analysis of geometric errors associated with five-axis machining centre in improving the quality of cam profile显示文摘 | Binit Kumar Jha Anjani Kumar | 2003 | International Journal of Machine Tools and Manufacture2003，，6： | 1 |
| 4 | Analysis of geometric errors associated with five-axis machining centre in improving the quality of cam profile显示文摘 | Binit Kumar Jha Anjani Kumar | 2003 | International Journal of Machine Tools & Manufacture2003，43，6： | 1 |
| 5 | 急性胰腺炎的影像学术语:基于2012亚特兰大分类标准的解读显示文摘2012年,在多个国家及国际学会的支持下,亚特兰大工作组基于网络共识对急性胰腺炎Atlanta分类系统(1992年版)进行了修订。修订版明确了急性胰腺炎的两个病期:早期和晚期。急性胰腺炎可分为间质水肿性胰腺炎和坏死性胰腺炎两类。其严重程度可依照器官衰竭和局部/系统并发症情况分为轻度、中重度和重度三个水平。根据胰腺炎的类型,胰周积聚可分为急性胰周积液、胰腺假性囊肿和包裹性坏死。熟悉修订版中的术语对于影像学结果的准确交流是十分必要的。本文将对这些更新的术语进行总结,并通过图例来呈现相应的影像学结果。 | Binit Sureka Kalpana Bansal Yashwant Patidar Ankur Arora | 2016 | Gastroenterology Report2016，4，1： | 1 |
| 6 | Analysis of geometric errors associated with five-ax is machining centre in improving the quality of cam profile显示文摘 | Binit K J Anjani K | 2003 | International Journal ofequipment Tools & Manufacture2003，43，6： | 1 |
| 7 | Analysis of geometric errors associ- ated with five-axis machining centre in improving the quality of cam profile显示文摘 | Binit Kumar Jha Anjani Kumar | 2003 | International Journal of Machine Tools &Manufacture2003，43，6： | 1 |
| 8 | Analysis of geometric errors associated with five-axis machining centre in improving the quality of cam profile显示文摘 | BINIT K J ANJANI K | 2003 | International Journal of Machine Tools & Manufacture2003，43，6： | 1 |
| 9 | Analysis of geometric errors associated with five-axis machining centre in improving the quality of cam profile显示文摘 | BINIT K J ANJANI K | 2003 | International Journal of Machine Tools & Manufacture2003，43，6： | 1 |
| 10 | Arc of riolan显示文摘 | Binit S Mittal MK | 2014 | Indian J Med Res2014，139，6： | 1 |
| 11 | 肝内假性囊肿自发破裂溃入下腔静脉显示文摘We present an extremely rare case of caudate lobe intrahepatic pancreatic pseudocyst with spontaneous rupture into the inferior vena cava(IVC).A 58-year-old male,a chronic alcoholic,presented with features of pancreatitis for which imaging was done.Ultrasound and contrast-enhanced computed tomography were carried out,which revealed intrahepatic pancreatic pseudocyst in the caudate lobe of the liver.There was suggestion of spontaneous rupture of the pseudocyst into the IVC,which was well delineated on imaging. | Yashwant Patidar Binit Sureka Vaibhav Pratap Singh Kalpana Bansal Rakhi Maiwall | 2018 | Gastroenterology Report2018，6，3： | 0 |
| 12 | 更低通胀水平、更高利润增长率、更高波动性 BRICs高增长影响的“双高一低”显示文摘以购买力平价汇率计算的各国和全球趋势增长率显示,以BRICs(巴西、俄罗斯、印度、中国)为代表的新兴市场国家对全球经济增长率的影响自上世纪90年代以来显著超过以G7为代表的发达市场国家。这表明,近期全球化趋势开始让新兴市场国家特别是BRICs受益。BRICs贡献的趋势增长率的高增长给全球市场带来的是更低的通胀水平、更高的利润增长率和更高的波动性。 | Binit Patel Mo nica Fuentes Anna Stupnytska 于欣(译) | 2005 | 新财富2005，，11： | 0 |
| 13 | Thoracic perspective revisited in chronic liver disease显示文摘A variety of chest manifestations are seen in patients with chronic liver diseases,namely hepatopulmonary syndrome,portopulmonary hypertension,intrathoracic portosystemic collaterals,hepatic hydrothorax,infections,drug-induced changes,manifestations of hepatocellular carcinoma,gynecomastia,acute respiratory distress syndrome,autoimmune changes,aspiration pneumonitis and changes due to a1-antitrypsin deficiency.Gastroenterologists and radiologists should be aware of these entities;knowledge of the imaging findings specific to each condition is of prime importance for managing such patients. | Binit Sureka Kalpana Bansal Yashwant Patidar Sachin Kumar Ankur Arora | 2015 | Gastroenterology Report2015，3，3： | 0 |
| 14 | Cinnamomum camphora: a long history for epidemics control显示文摘Camphor(C_(10)H_(16)O)is a white crystalline solid exist in enantiomeric form R and S camphor.It is a terpenoid obtained from turpentine oil.Synthetically it is synthesized by catalytic process as alpha pinene.Naturally camphor is obtained by steam distillation of woods of Cinnamomum camphora tree,also known as Camphor tree,camphor laure and camphor wood.Camphor has many pharmacological properties.It acts as antiviral,anticancerous,antimicrobial,insecticidal,anticoccidial,anti-nociceptive and antitussive drug.In addition,it can be used as skin penetrating enhancer.Camphor gives a soothing and cooling effect,which helps to reduce pain.The reason behind its soothing effect is camphor act as a counter-irritant by activating heat sensitive transient receptor potential vanilloid subtype 1 and transient receptor potential vanilloid subtype 3 receptors and inhibits the transient receptor potential melastatin-subfamily member 8 receptor.As a result,these receptors provide a sensation of scalding heat and pain(nociception)and could be used to treat neuropathic pain associated with multiple sclerosis,chemotherapy,or amputation,as well as pain associated with the inflammatory response of damaged tissue such as in osteoarthritis.Camphor has a history of epidemics cure.During leishmaniosis(kala-azar)pandemic in 14th century,camphor was used as fumigant to control the spread of plague in European countries.In 19th century when cholera,small pox and influenza spreads,camphor was used as mothballs in Indian subcontinent as a(cough reliever)agent.During 18th century Russian influenza“flu pandemic”founder of Homeopathy Hahnemann in 1831,published his research work on camphor and suggested camphor as a“divine remedy”for influenza given in extremely small doses.In the same year,several companies launched to sell menthol rub as natural rub ointment consisting camphor as prevention measures for spread of influenza.As the recent epidemic of COVID-19 arises,prevention and control of spread of disease is an alarming issue.This article covered the glimpse of uses and importance of camphor in the history of epidemic cure. | Rakhi Mishra Binit Dwivedi | 2021 | TMR Integrative Medicine2021，5，31： | 0 |
| 15 | Reaction mechanism of hydrogen activation by frustrated Lewis pairs显示文摘Typically, a Lewis acid and a Lewis base can react with each other and form a classical Lewis adduct. The neutralization reaction can however be prevented by ligating the acid and base with bulky substituents and the resulting complex is known as a 'frustrated Lewis pair'(FLP). Since the Lewis acid and base reactivity remains in the formed complex, FLPs can display interesting chemical activities, with promising applications in catalysis. For example, FLPs were shown to function as the first metal-free catalyst for molecular hydrogen activation. This, and other recent applications of FLPs, have opened a new thriving research field. In this short-review, we recapitulate the computational and experimental studies of the H_2 activation by FLPs. We discuss the thus-far uncovered mechanistic aspects, including pre-organization of FLPs,the reaction paths for the activation, the polarization of He H bond and other factors affecting the reactivity. We aim to provide a rather complete mechanistic picture of the H_2 activation by FLPs, which has been under debate for decades since the first discovery of FLPs. This review is meant as a starting point for future studies and a guideline for industrial applications. | Lei Liu Binit Lukose Pablo Jaque Bernd Ensing | 2019 | Green Energy & Environment2019，4，1： | 0 |
| 16 | 肝移植术后并发症的影像学诊断全景显示文摘肝脏是第二常见的移植器官,仅次于肾脏,显然,肝脏疾病是全球范围内一种常见且严重的疾病。随着外科学、肿瘤学及影像学技术的发展,原位肝移植已经成为许多终末期肝病患者的一线治疗方案。超声和多普勒彩超是评估肝移植术后液体积聚和血管并发症最经济、性价比最高的影像学方法。CT可用以进一步证实超声检查结果,并可用于肺部并发症的诊断。磁共振成像可用于发现肝管并发症、胆漏及神经系统并发症。本文论述了对于肝移植术后各种可能的并发症,如何进行影像学技术的选择。 | Binit Sureka Kalpana Bansal S Rajesh Amar Mukund Viniyendra Pamecha Ankur Arora | 2016 | Gastroenterology Report2016，4，2： | 0 |
| 17 | 通过核心蛋白簇分析鉴定导致甲硝唑耐药的幽门螺杆菌变异位点显示文摘背景:在根治幽门螺杆菌(Hp)的标准三联治疗中,甲硝唑是其中的一种一线药物。因此,甲硝唑耐药是一个重大健康问题。RdxA失活被认为是甲硝唑耐药的主要机制。然而,表达功能性RdxA蛋白的Hp菌珠更容易对甲硝唑耐药,提示还存在其他一些导致甲硝唑耐药的机制。方法:我们对121份Hp菌珠进行了全基因组测序,其中73份是甲哨唑耐药菌珠。对包含全长RdxA基因的Hp临床菌珠的核心蛋白簇进行序列比对分析。对耐药菌珠与敏感菌珠的差异位点进行分析,以鉴定出差异基因及其导致甲硝唑耐药的氨基酸改变。结果:在73份甲硝唑耐药菌珠中,25份(34%)是由于RdxA无义突变所导致。对来自剩余48份甲硝唑耐药菌珠和48份甲硝唑敏感菌株的核心蛋白簇进行分析发现,有4个差异位点与甲硝唑耐药显著相关。这4个位点包括RdxA的R16H/C位点、内膜蛋白RclC(HP0565)的D85N位点、biotin carboxylase蛋白(HP0370)的V265I位点和putative threonylcarbamoyl-AMP合酶(HP0918)的A51V/T位点。结论:我们发现了Hp对甲硝唑耐药的一些新的潜在机制,值得进一步研究。 | Eng-Guan Chua Aleksandra W.Debowski KMary Webberley Fanny Peters Binit Lamichhane Mun-Fai Loke Jamuna Vadivelu Chin-Yen Tay Barry J.Marshall Michael J.Wise | 2019 | Gastroenterology Report2019，7，1： | 0 |
| 18 | Outcomes and efficacy of magnetic resonance imaging-compatible sacral nerve stimulator for management of fecal incontinence: A multi-institutional study显示文摘BACKGROUND Fecal incontinence(FI)is an involuntary passage of fecal matter which can have a significant impact on a patient’s quality of life.Many modalities of treatment exist for FI.Sacral nerve stimulation is a well-established treatment for FI.Given the increased need of magnetic resonance imaging(MRI)for diagnostics,the In-terStim which was previously used in sacral nerve stimulation was limited by MRI incompatibility.Medtronic MRI-compatible InterStim was approved by the United States Food and Drug Administration in August 2020 and has been widely used.AIM To evaluate the efficacy,outcomes and complications of the MRI-compatible InterStim.METHODS Data of patients who underwent MRI-compatible Medtronic InterStim placement at UPMC Williamsport,University of Minnesota,Advocate Lutheran General Hospital,and University of Wisconsin-Madison was pooled and analyzed.Patient demographics,clinical features,surgical techniques,complications,and outcomes were analyzed.Strengthening the Reporting of Observational studies in Epidemiology(STROBE)cross-sectional reporting guidelines were used.RESULTS Seventy-three patients had the InterStim implanted.The mean age was 63.29±12.2 years.Fifty-seven(78.1%)patients were females and forty-two(57.5%)patients had diabetes.In addition to incontinence,overlapping symptoms included diarrhea(23.3%),fecal urgency(58.9%),and urinary incontinence(28.8%).Fifteen(20.5%)patients underwent Peripheral Nerve Evaluation before proceeding to definite implant placement.Thirty-two(43.8%)patients underwent rechargeable InterStim placement.Three(4.1%)patients needed removal of the implant.Migration of the external lead connection was observed in 7(9.6%)patients after the stage I procedure.The explanation for one patient was due to infection.Seven(9.6%)patients had other complications like nerve pain,hematoma,infection,lead fracture,and bleeding.The mean follow-up was 6.62±3.5 mo.Sixty-eight(93.2%)patients reported significant improvement of symptoms on follow-up evaluation.CONCLUSION This study shows promising results with significant symptom improvement,good efficacy and good patient outcomes with low complication rates while using MRI compatible InterStim for FI.Further long-term follow-up and future studies with a larger patient population is recommended. | Binit Katuwal Amy Thorsen Kunal Kochar Ryba Bhullar Ray King Ernesto Raul Drelichman Vijay K Mittal Jasneet Singh Bhullar | 2024 | World Journal of Radiology2024，16，2： | 0 |
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