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| 1 | m^6A mRNA methylation sustains Treg suppressive functions显示文摘 | Jiyu Tong Guangchao Cao Ting Zhang Esen Sefik Maria Carolina Amezcua Vesely James P Broughton Shu Zhu Huabin Li Bin Li Lei Chen Howard Y Chang Bing Su Richard A Flavell Hua-Bing Li | 2018 | Cell Research2018，28，2： | 30 |
| 2 | Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms显示文摘协调的子宫胚胎的轴形成并且蜕膜的改变是哺乳动物的培植以后的胚胎开发的特点。胚胎子宫的取向在起始的培植被决定并且与蜕膜的开发同步。然而,控制这些事件的分子的机制留下尽管有它的发现逃犯很长时间以前。在现在的学习,我们发现了 Rbpj 的那子宫特定的删除,槽口发信号的原子变换器,在培植以后的阶段导致了反常胚胎子宫的取向和蜕膜的 patterning,导致实质的胚胎损失。我们进一步表明在胚胎附件以前, Rbpj 授与在时间上经由身体上与子宫的雌激素受体交往的子宫的腔形状转变(ERα) 以一种槽口小径无关的方式,它为在有子宫的轴的排列的胚胎取向的起始的建立是必要的。当时在培植以后的阶段, Rbpj 直接以一种槽口小径依赖者方式调整子宫的矩阵 metalloproteinase 的表示,它为正常被要求培植以后的蜕膜的改变。这些结果证明子宫的 Rbpj 为经由指示起始的胚胎子宫的取向并且以一种阶段特定的方式保证正常蜕膜的 patterning 的正常胚胎开发是必要的。我们的数据也证实正常哺乳动物的胚胎子宫的取向要求的概念合适的指导从发展地控制了子宫的发信号。 | Shuang Zhang Shuangbo Kong Bingyan Wang Xiaohong Cheng Yongjie Chen Weiwei Wu Qiang Wang Junchao Shi Ying Zhang Shumin Wang Jinhua Lu John P Lydon Francesco DeMayo Warren S Pear Hua Han Haiyan Lin Lei Li Hongmei Wang Yan-ling Wang Bing Li Qi Chen Enkui Duan Haibin Wang | 2014 | Cell Research2014，24，8： | 12 |
| 3 | A gene expression estimator of intramuscular fat percentage for use in both cattle and sheep显示文摘Background:The expression of genes encoding proteins involved in triacyglyceride and fatty acid synthesis and storage in cattle muscle are correlated with intramuscular fat(IMF)%.Are the same genes also correlated with IMF%in sheep muscle,and can the same set of genes be used to estimate IMF%in both species?Results:The correlation between gene expression(microarray) and IMF%in the longissimus muscle(LM) of twenty sheep was calculated.An integrated analysis of this dataset with an equivalent cattle correlation dataset and a cattle differential expression dataset was undertaken.A total of 30 genes were identified to be strongly correlated with IMF%in both cattle and sheep.The overlap of genes was highly significant,8 of the 13 genes in the TAG gene set and 8 of the 13 genes in the FA gene set were in the top 100 and 500 genes respertively most correlated with IMF%in sheep,P-value = 0.Of the 30 genes,CIDEA,THRSP,ACSM1,DGAT2 and FABP4 had the highest average rank in both species.Using the data from two small groups of Brahman cattle(control and Hormone growth promotant-treated[known to decrease IMF%in muscle]) and 22 animals in total,the utility of a direct measure and different estimators of IMF%(ultrasound and gene expression) to differentiate between the two groups were examined.Directly measured IMF%and IMF%estimated from ultrasound scanning could not discriminate between the two groups.However,using gene expression to estimate IMF%discriminated between the two groups.Increasing the number of genes used to estimate IMF%from one to five significantly increased the discrimination power;but increasing the number of genes to 15 resulted in little further improvement.Conclusion:We have demonstrated the utility of a comparative approach to identify robust estimators of IMF%in the LM in cattle and sheep.We have also demonstrated a number of approaches(potentially applicable to much smaller groups of animals than conventional methods) to using gene expression to rank animals for IMF%within a single farm/treatment,or to estimate differences in IMF%between two farms/treatments. | Bing Guo Kritaya Kongsuwan Paul L Greenwood Guanghong Zhou Wangang Zhang Brian P Dalrymple | 2014 | Journal of Animal Science and Biotechnology2014，5，4： | 6 |
| 4 | Estimating saturated hydraulic conductivity in spatially variable fields using neural network ensembles 显示文摘 | KAMBAN P AMIN E BING C S | 2006 | Soil Science Society of America Journal2006，70，6： | 1 |
| 5 | Online information search: vacation planning process 显示文摘 | Bing P Daniel R | 2006 | Annals of Tourism Research2006，33，3： | 1 |
| 6 | Performance of sub- pixel registration algorithms in digital image correlation 显示文摘 | Bing P Hui-Min X Bo-Qin X | 2006 | Measurement Science and Technology2006，17，6： | 1 |
| 7 | Integration of microfabricated devices to capillary electrophoresis-electrospray mass spectrometry using a low dead volume connection: application to rapid analysis of proteolytic digests显示文摘 | Li J J Thibault P Bings N H | 1999 | Analytical Chemistry1999，71，15： | 1 |
| 8 | Impact of sodium sulfate on soil frost heaving in an open system显示文摘 | Bing H He P Yang C | 2007 | Applied Clay Science2007，35，34： | 1 |
| 9 | Synthesis and Characteriza- tion of Aminate Poly(2,6-dimethyl-l,4-phenylene ether)显示文摘 | Yan P Yuhui H Bing L | 1996 | Journal of Polymer Science1996，，61： | 1 |
| 10 | SketchPadN-D : WYDI- WYG sculpting and editing in high-dimensional space 显示文摘 | Wang Bing Ruchikachom P Mueller K | 2013 | IEEE Transactions on Visualization and Computer Graphics2013，19，12： | 1 |
| 11 | Involvement of protein kinase C in 5-HT-evoked thermal hyperalgesia and spinal fos protein expression in the rat显示文摘 | Chen X Bing F Dai P | 2006 | Pharmacol Biochem Behav2006，84，1： | 1 |
| 12 | Experimental investigations on the influence of cyclical freezing and thawing on physical and mechanical properties of saline soil显示文摘 | Bing H He P | 2011 | Environmental Earth Sciences2011，64，2： | 1 |
| 13 | 显示文摘 | Zhu L P Liao G H Bing N C | 2011 | Journal of Solid State Chemistry2011，184，： | 1 |
| 14 | Microbubble dynamics visualized in the intact capillary circulation 显示文摘 | Feinstein S B Shah P M Bing R J | 1984 | J Am Coil Cardiol1984，4，3： | 1 |
| 15 | Optimizing deployment of Internet gateway in Wireless Mesh Networks 显示文摘 | He Bing Xie Bin Agrawal D P | 2008 | Computer Communications2008，31，7： | 1 |
| 16 | The allocation of risk in PPP/PFI construction pro-jects in the UK显示文摘 | LI Bing AKINTOYE K EDWARDS P J | 2005 | International Journal of ProjectManagement2005，23，1： | 1 |
| 17 | Endothelium - dependent vascular effects of pycnogenol 显示文摘 | FITZPATRICK D F BING B ROHDEWALD P | 1998 | Cardiovasc Pharmacol1998，32，4： | 1 |
| 18 | DUROS technology delivers peptides and proteins at consistent rate continuously for 3 to 12 months 显示文摘 | Catherine M R Thomas R A Bing Y Janice D John P C Scott D L | 2008 | Journal of Diabetes Science and Technology2008，2，3： | 1 |
| 19 | 1,25-Dihydroxyvitamin D3 inhibits the cy- tokine-induced secretion of MCP-1 and reduces monocyte recruitment by human preadipocytes 显示文摘 | Gao D Trayhurn P Bing C | 2013 | Int J Obes ( Lond )2013，37，3： | 1 |
| 20 | Synthesis and characterization of folate-PEG-grafted-hyperbranched-PEI for tumor-targeted gene delivery 显示文摘 | BING L MING L H ZHONG P X | 2008 | Biochemical and Biophysicial Research Commtmication2008，14，1： | 1 |
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