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| 1 | 经皮冠状动脉介入的遥控操作:概念、验证和首次人体临床试验显示文摘OBJECTIVES: This study was designed to assess the feasibility and safety of a Remote Navigation System(RNS, NaviCath, Haifa, Israel) in which the angioplasty guidewire, the balloon, and the stent are navigated via a computerized system. BACKGROUND: Percutaneous coronary interventions(PCIs) are manually performed under fluoroscopic guidance, requiring lead protection for the operators. A system in which the operator can remotely, safely, and precisely navigate the procedure during PCI would have clear advantages. METHODS: The RNS involves a computer-controlled wire and delivery system navigator. Following preclinical validation, the system was assessed in patients undergoing single-vessel PCI. RESULTS: The study involved 18 patients(age 55.9 years, 16% women). The RNS successfully crossed lesions with the guidewire in 17 patients. The stent was then advanced by the advance/rotate mode and adequately positioned in 15 of 17 cases. Technical malfunction was encountered in three patients in whom the procedure was successfully completed manually. Direct stenting was employed in 10 of 18 patients,pre-dilation in 7 patients, and after-stent balloon dilation in 5 patients. The total fluoroscopy time for 17 RNS patients was compared with the corresponding time of 20 consecutive patients who underwent standard single lesion PCI. Fluoroscopy time was similar for both procedures, with 8.8± 4.8 min with the RNS versus 9.1± 3.5 min with the standard techniques(p=NS). Clinical success was 100% and technical success 94% for the guidewire and 83% for the overall procedure. CONCLUSIONS: The use of the RNS for guidewire, balloon, and stent manipulation during PCI appears safe and feasible for the treatment of patients with coronary stenosis. The system offers operator radiation safety and may enhance precision of stent placement and balloon dilation strategies. | Beyar R Gruberg L Deleanu D. 徐永城 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，5： | 3 |
| 2 | Influence of pleural pressure variations on cardiovascular system dynamics:a model study显示文摘 | GOLDSTEIN Y BEYAR R SIDEMAN S | 1988 | Med & Biol Eng & Comput1988，26，： | 1 |
| 3 | Intermediate coronary artery stenosis: evidence- based decisions in interventions to avoid the oculostenotic reflex 显示文摘 | Patil CV Beyar R | 2000 | Int J Cardiovasc Intervent2000，3，： | 1 |
| 4 | Coronary perforation 2006-watch for the wire显示文摘 | Roguin A Beyar R | 2005 | J Invasive Cardiol2005，17，11： | 1 |
| 5 | The ' jaundiced heart': a possible explanation for postoperative shock in ob- structive jaundice 显示文摘 | Green J Beyar R Sideman S | 1986 | Surgery1986，100，： | 1 |
| 6 | Real case virtual reality training prior to carotid artery stenting显示文摘 | Roguin A Beyar R | 2010 | Catheter Cardiovasc Interv2010，75，2： | 1 |
| 7 | “No‐reflow” phenomenon during percutaneous carotid angioplasty in a scleroderma patient显示文摘 | Sergey Yalonetsky Luis Gruberg Rafael Beyar | 2004 | Acute Cardiac Care2004，，2： | 1 |
| 8 | 'No-reflow' Phenomenon dur- ing Percutaneous carotid angioplasty in a selemderma patient显示文摘 | Yalonetsky S Gmberg L Beyar R | 2004 | Int J Cardiovasc lntervent2004，6，1： | 1 |
| 9 | Novel approaches to reduce restenosis显示文摘 | | 2004 | Ann N Y Acad Sci2004，1015，： | 1 |
| 10 | The 'jaundiced heart': a possible explanation for postoperative shock in obstruc- tive jaundice显示文摘 | GREEN J BEYAR R SIDEMAN S | 1986 | Surgery1986，100，1： | 1 |
| 11 | Model studies of the effects of the thoracic pressure on the circulation 显示文摘 | Beyar R Goldstein Y | 1987 | Annals of Biomedical Engineering1987，15，： | 1 |
| 12 | Serum blood urea nitrogen and long-term mortality in acute ST-elevation myocardial infarction显示文摘 | Aronson D Hammerman H Beyar R | 2008 | Int J Cardiol2008，127，3： | 1 |
| 13 | Cerebral embolic protection devices and percu-taneous carotid artery stenting显示文摘 | Gruberg L Beyar R | 2005 | Int J Cardiovasc Intervent2005，7，3： | 1 |
| 14 | Effects of load manipulations,heart rate,and contractility on left ventricular apical rotation experimental study in anesthetized dogs显示文摘 | Kroeker CA Tyberg JV Beyar R | 1995 | Circulation1995，92，： | 1 |
| 15 | Hemodynamics anf Left Ventricular Contraction: Effects of Load Manipulations, Heart Rate, and Contractility on Left Ventricular Apical Rotation: An Experimental Study in Anesthetized Dogs显示文摘 | Carol A. Gibbons Kroeker John V. Tyberg Rafael Beyar | 1995 | Circulation1995，，1： | 1 |
| 16 | 'No-reflow'phenomenon during percutaneous carotid angioplasty in a scleroderma patient显示文摘 | Gruberg L Beyar R | 2004 | Int J Cardiovasc Intervent2004，6，： | 1 |
| 17 | Recommendations on stent manufacture, implantation and utilization显示文摘 | Balcon R Beyar R Chierchia S | 1997 | European Heart Journal1997，18，： | 1 |
| 18 | Real case virtual reality training prior to carotid artery stenting显示文摘 | Roguin A Beyar R | | 0，，2： | 1 |
| 19 | Predictive value of white blood cell subtypes for long-term outcome following myocardial infarction显示文摘 | Robert Dragu Shafik Huri Robert Zuckerman Mahmoud Suleiman Diab Mutlak Yoram Agmon Michael Kapeliovich Rafael Beyar Walter Markiewicz Haim Hammerman Doron Aronson | 2006 | Atherosclerosis2006，，1： | 1 |
| 20 | Three-dimensional automatic quantitative analysis of intravascular ultrasound images显示文摘 | Kovalski G Beyar R Shofti R | 2000 | Ultrasound Med Biol2000，26，： | 1 |
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