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| 1 | Milk exosomes:Nature’s abundant nanoplatform for theranostic applications显示文摘Exosomes are a unique subpopulation of naturally occurring extracellular vesicles which are smaller intracellular membrane nanoparticle vesicles.Exosomes have proven to be excellent nanocarriers for carrying lipids,proteins,mRNAs,non-coding RNAs,and DNAs,and disseminating long-distance intercellular communications in various biological processes.Among various cell-line or biological fluid derived exosomes,milk exosomes are abundant in nature and exhibit many nanocarrier characteristics favorable for theranostic applications.To be an effective delivery carrier for their clinical translation,exosomes must inbuilt loading,release,targeting,and imaging/tracking characteristics.Considering the unmet gaps of milk exosomes in theranostic technology it is essential to focus the current review on drug delivery and imaging applications.This review delineates the efficiency of exosomes to load therapeutic or imaging agents and their successful delivery approaches.It is emphasized on possible modifications of exosomes towards increasing the stability and delivery of agents.This article also summarizes the specific applications and the process of developing milk exosomes as a future pharmaceutical drug delivery vehicle. | Benilde Adriano Nycol M.Cotto Neeraj Chauhan Meena Jaggi Subhash C.Chauhan Murali M.Yallapu | 2021 | Bioactive Materials2021，6，8： | 2 |
| 2 | Update on the predictive value of D-dimer in patients with idiopathic venous thromboembolism显示文摘 | BENILDE C GUALTIERO P | 2010 | Thromb Res2010，125，： | 1 |
| 3 | Diagnosis and treatment of disseminated intravascular coagulation: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET)显示文摘 | Marcello Di Nisio Francesco Baudo Benilde Cosmi Armando D’Angelo Andrea De Gasperi Alessandra Malato Mario Schiavoni Alessandro Squizzato | 2011 | Thrombosis Research2011，，5： | 1 |
| 4 | Influence of age,sex and vitamin status on fasting and postmethionine load plasma homocysteine levels显示文摘 | Simonetta Sassi Benilde Cosmi Gualtiero Palareti | 2002 | Haematologica2002，87，9： | 1 |
| 5 | High plasma lev- els of factor VIII and risk of recurrence of venous thrombo- embolism显示文摘 | Cristina L Benilde C Michela C | 2004 | Br J Haematol2004，124，4： | 1 |
| 6 | Estimation of the surface tension of a solid:application to a liquid crystalline polymer显示文摘 | Nata'lia TC Joaquim J M R Benilde J VS | 1997 | Colloid and Interface Science1997，189，： | 1 |
| 7 | Fe 2 O 3 /aluminum thermite reaction intermediate and final products characterization显示文摘 | Luísa Dur?es Benilde F.O. Costa Regina Santos António Correia José Campos António Portugal | 2007 | Materials Science & Engineering A2007，，1： | 1 |
| 8 | Additive thrombin inhibition by fast moving heparin and dermatan sulfate explains the anticoagulant effect of sulodexide, a natural mixture of glycosaminoglycans显示文摘 | Benilde C Michela C Cristina L | 2003 | Thrombosis Research2003，109，： | 1 |
| 9 | Use of D-dimer testing to determine duration of anticoagulation, risk of cardiovascular events and occult cancer after a first episode of idiopathic venous thromboembolism: the extended follow-up of the PROLONG study显示文摘 | Benilde Cosmi Cristina Legnani Alberto Tosetto Vittorio Pengo Angelo Ghirarduzzi Adriano Alatri Domenico Prisco Daniela Poli Armando Tripodi Gualtiero Palareti | 2009 | Journal of Thrombosis and Thrombolysis2009，，4： | 1 |
| 10 | High plasma levels of factor Ⅷ and risk of recurrence of venous thromboembolism 显示文摘 | BENILDE C MICHELA C | 2004 | Br J Haematol2004，124，4： | 1 |
| 11 | High plasma levels of factorVIII and risk of recurrence of venous thromboembolism显示文摘 | Cristina L Benilde C Michela C | 2004 | Br JHaematol2004，124，4： | 1 |
| 12 | Bleeding with anticoagu- !ation therapy-Who is at risk, and how best to identify such ~atients 显示文摘 | Gqualtiero Palareti Benilde Cosmi | 2009 | Thromb Haemost2009，102，2： | 1 |
| 13 | Wells rule and D-dimer for the diagnosis of islated disral deep vein thrombosis显示文摘 | Michelangelo S Benilde C Cristina L | | 0，，11： | 1 |
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